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The map label for this gene is cysI

Identifier: 108763120

GI number: 108763120

Start: 2712415

End: 2714103

Strand: Reverse

Name: cysI

Synonym: MXAN_2334

Alternate gene names: 108763120

Gene position: 2714103-2712415 (Counterclockwise)

Preceding gene: 108761948

Following gene: 108760971

Centisome position: 29.7

GC content: 69.15

Gene sequence:

>1689_bases
ATGAGCCACCAGCCCAAGCCTCTCTCCGAAGTGGAGCACATCAAGACCCAGAGCCGCCTGCTCCGGGGAAGTCTGGCGGA
GAGCCTGGAGGACCCGGTGACGGGCGGCCTCGCCACGCCGGACACCAACCTCATCAAGTTCCACGGCAGCTATCAGCAGG
ACGACCGCGACGTGCGCGAGGAGCGGCGTCAGCAGAAGCTGGAGCCCGACTACAGCTTCATGCTCCGCACCCGCCTGCCT
GGAGGCGTGTGCACACCGGCCCAGTGGCTGGTGATGGACGCCCTGGCGCGCGAGCACGCCAACCACACGCTGCGCATCAC
CACGCGGCAGGCCTTTCAGTTACACGGCGTCATCAAGGATGACCTCCGGCCCACCATCGCCCGCATCAACGAAGCGATGA
TGGACACGCTGGCCGCCTGCGGCGACGTGAACCGCAACGTGCTGTGCAACCCCAATCCGGTGGACTCGCGCGTCCACGAG
ACGGTGTACCAGTGGGCGGTGCGCATCTCCGAGCACCTGCTGCCGAAGACGCGCGCCTACTACGAAGTCTGGCTGGGGAA
GGAGAAGGTGGCCGGCGGTGAGGACGAGCCCATCTACGGCGCCACGTACCTGCCCCGGAAGTTCAAGGCCGCCGTGGCGG
TGCCGCCCCTCAACGACGTGGATGTCTTCGCGCAGGACCTGGGCTTCATCGCCATCATCGAAGGCGACGCGCTCGTGGGC
TTCAACGTCTCCGTGGGCGGCGGCATGGGCGCCACGCATGGTGACGCGGCCACCTATCCCCGGCTGGCGGACGTCGTCGG
CTTCATCCCGCCGGAGCAGACGCTCGCCGTCGCCGAGGAGGTGGTGAAGATTCACCGCGACTTCGGGGACCGCACCAACC
GCAAGCACGCGCGCCTGAAGTACGTCCTGGAGGAGCGCGGCGTTCCCTGGTTCACGGCAGAGCTGGAGAAGCGGCTCGGC
TTCCCGCTCCAGCCAGCGCGCCCCTTCGCTTTCGAGCACAACGGAGACCGCTTCGGGTGGACAGAGGGCCATGACGGCCG
GTGGCATCTGACGTTGCACCTGGACAGCGGCCGCGTGGCGGACCGGCCCGGCGCGCCGCACTTGACGGGCCTGCGGGAGA
TTGCGCGCATCCACACCGGGGACTTCCGGCTCACGGCGAACCAGAACCTCGTCATCGCAGGTGTGACGCCCGAGGCTCGC
GACGCCATCGGCGCGCTGGTGACGGCGCACGCGCTGGACAGCTTCCGCAGCGCCAGCCCGGTGCGTCGCAACGCGCTGGC
GTGCGTGGCGCTGCCGACGTGCGGGCTCGCCATGGCGGAGGCGGAGCGCTACCTGCCTACCTTCGTGGGACGGCTGGAGG
ACCGGCTGCGGGCGCATGGCCTGCAGGACGCCAACCTGCTGCTCCGCATCACCGGGTGCCCCAACGGCTGCGCGAGGCCG
TACCTGGCGGAGGTGGGACTCGTGGGCAAGGCGCCGGGCCGCTACAACCTGCACCTGGGCGGAGATGCGCGAGGCCAGCG
CCTCAGTCACCTCTACAGGGAGAACATCGACGAGGACGCCATCCTCGCCGCGCTGGAGCCATTGTTCGAAGGCTACGCAC
GCGAACGTCAGCCCGGTGAAGGCTTTGGCGACTTCGTGGTGCGCGCTGGCCACGTCCCCAGCCCAGCCGTTCAGCCTCGG
CCGTCCTGA

Upstream 100 bases:

>100_bases
CAAGAGCCGCGAGGACGCGCACGCCTGGCTCGAATCCCTGCGCGAGCAGCGGCGCTACCTGCGCGACGTCTACTGACCCA
TTCCGATTGCGAGCAACGAC

Downstream 100 bases:

>100_bases
GCCAACGCGGACCACGCGCGTGTTCAATCACTCGCGCCCCGCACCGCGGTGAGGAGCAGGTCGTACTTGCCGCCCAGGAA
CGTACGGAAGCCGTGCTGGT

Product: sulfite reductase subunit beta

Products: NA

Alternate protein names: SiR-HP; SiRHP

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSHQPKPLSEVEHIKTQSRLLRGSLAESLEDPVTGGLATPDTNLIKFHGSYQQDDRDVREERRQQKLEPDYSFMLRTRLP
GGVCTPAQWLVMDALAREHANHTLRITTRQAFQLHGVIKDDLRPTIARINEAMMDTLAACGDVNRNVLCNPNPVDSRVHE
TVYQWAVRISEHLLPKTRAYYEVWLGKEKVAGGEDEPIYGATYLPRKFKAAVAVPPLNDVDVFAQDLGFIAIIEGDALVG
FNVSVGGGMGATHGDAATYPRLADVVGFIPPEQTLAVAEEVVKIHRDFGDRTNRKHARLKYVLEERGVPWFTAELEKRLG
FPLQPARPFAFEHNGDRFGWTEGHDGRWHLTLHLDSGRVADRPGAPHLTGLREIARIHTGDFRLTANQNLVIAGVTPEAR
DAIGALVTAHALDSFRSASPVRRNALACVALPTCGLAMAEAERYLPTFVGRLEDRLRAHGLQDANLLLRITGCPNGCARP
YLAEVGLVGKAPGRYNLHLGGDARGQRLSHLYRENIDEDAILAALEPLFEGYARERQPGEGFGDFVVRAGHVPSPAVQPR
PS

Sequences:

>Translated_562_residues
MSHQPKPLSEVEHIKTQSRLLRGSLAESLEDPVTGGLATPDTNLIKFHGSYQQDDRDVREERRQQKLEPDYSFMLRTRLP
GGVCTPAQWLVMDALAREHANHTLRITTRQAFQLHGVIKDDLRPTIARINEAMMDTLAACGDVNRNVLCNPNPVDSRVHE
TVYQWAVRISEHLLPKTRAYYEVWLGKEKVAGGEDEPIYGATYLPRKFKAAVAVPPLNDVDVFAQDLGFIAIIEGDALVG
FNVSVGGGMGATHGDAATYPRLADVVGFIPPEQTLAVAEEVVKIHRDFGDRTNRKHARLKYVLEERGVPWFTAELEKRLG
FPLQPARPFAFEHNGDRFGWTEGHDGRWHLTLHLDSGRVADRPGAPHLTGLREIARIHTGDFRLTANQNLVIAGVTPEAR
DAIGALVTAHALDSFRSASPVRRNALACVALPTCGLAMAEAERYLPTFVGRLEDRLRAHGLQDANLLLRITGCPNGCARP
YLAEVGLVGKAPGRYNLHLGGDARGQRLSHLYRENIDEDAILAALEPLFEGYARERQPGEGFGDFVVRAGHVPSPAVQPR
PS
>Mature_561_residues
SHQPKPLSEVEHIKTQSRLLRGSLAESLEDPVTGGLATPDTNLIKFHGSYQQDDRDVREERRQQKLEPDYSFMLRTRLPG
GVCTPAQWLVMDALAREHANHTLRITTRQAFQLHGVIKDDLRPTIARINEAMMDTLAACGDVNRNVLCNPNPVDSRVHET
VYQWAVRISEHLLPKTRAYYEVWLGKEKVAGGEDEPIYGATYLPRKFKAAVAVPPLNDVDVFAQDLGFIAIIEGDALVGF
NVSVGGGMGATHGDAATYPRLADVVGFIPPEQTLAVAEEVVKIHRDFGDRTNRKHARLKYVLEERGVPWFTAELEKRLGF
PLQPARPFAFEHNGDRFGWTEGHDGRWHLTLHLDSGRVADRPGAPHLTGLREIARIHTGDFRLTANQNLVIAGVTPEARD
AIGALVTAHALDSFRSASPVRRNALACVALPTCGLAMAEAERYLPTFVGRLEDRLRAHGLQDANLLLRITGCPNGCARPY
LAEVGLVGKAPGRYNLHLGGDARGQRLSHLYRENIDEDAILAALEPLFEGYARERQPGEGFGDFVVRAGHVPSPAVQPRP
S

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family

Homologues:

Organism=Escherichia coli, GI1789122, Length=553, Percent_Identity=52.0795660036166, Blast_Score=610, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6322597, Length=583, Percent_Identity=46.3121783876501, Blast_Score=548, Evalue=1e-157,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): CYSI_MYXXD (Q1D9W9)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_630554.1
- ProteinModelPortal:   Q1D9W9
- SMR:   Q1D9W9
- STRING:   Q1D9W9
- GeneID:   4106874
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_2334
- TIGR:   MXAN_2334
- eggNOG:   COG0155
- HOGENOM:   HBG626671
- OMA:   ESERVFP
- PhylomeDB:   Q1D9W9
- ProtClustDB:   PRK13504
- BioCyc:   MXAN246197:MXAN_2334-MONOMER
- HAMAP:   MF_01540
- InterPro:   IPR011786
- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066
- PRINTS:   PR00397
- TIGRFAMs:   TIGR02041

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr; SSF55124 NiR_SiRalpha_1/3

EC number: =1.8.1.2

Molecular weight: Translated: 62087; Mature: 61956

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00365 NIR_SIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQPKPLSEVEHIKTQSRLLRGSLAESLEDPVTGGLATPDTNLIKFHGSYQQDDRDVRE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
ERRQQKLEPDYSFMLRTRLPGGVCTPAQWLVMDALAREHANHTLRITTRQAFQLHGVIKD
HHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCHHH
DLRPTIARINEAMMDTLAACGDVNRNVLCNPNPVDSRVHETVYQWAVRISEHLLPKTRAY
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
YEVWLGKEKVAGGEDEPIYGATYLPRKFKAAVAVPPLNDVDVFAQDLGFIAIIEGDALVG
HHHHCCCHHCCCCCCCCCCCCCCCCHHHCCEEECCCCCHHHHHHHCCCEEEEEECCEEEE
FNVSVGGGMGATHGDAATYPRLADVVGFIPPEQTLAVAEEVVKIHRDFGDRTNRKHARLK
EEEEECCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
YVLEERGVPWFTAELEKRLGFPLQPARPFAFEHNGDRFGWTEGHDGRWHLTLHLDSGRVA
HHHHHCCCCEEHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEEEEECCCCCC
DRPGAPHLTGLREIARIHTGDFRLTANQNLVIAGVTPEARDAIGALVTAHALDSFRSASP
CCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
VRRNALACVALPTCGLAMAEAERYLPTFVGRLEDRLRAHGLQDANLLLRITGCPNGCARP
HHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
YLAEVGLVGKAPGRYNLHLGGDARGQRLSHLYRENIDEDAILAALEPLFEGYARERQPGE
HHHHCCCEECCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GFGDFVVRAGHVPSPAVQPRPS
CCHHHHEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SHQPKPLSEVEHIKTQSRLLRGSLAESLEDPVTGGLATPDTNLIKFHGSYQQDDRDVRE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
ERRQQKLEPDYSFMLRTRLPGGVCTPAQWLVMDALAREHANHTLRITTRQAFQLHGVIKD
HHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCHHH
DLRPTIARINEAMMDTLAACGDVNRNVLCNPNPVDSRVHETVYQWAVRISEHLLPKTRAY
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
YEVWLGKEKVAGGEDEPIYGATYLPRKFKAAVAVPPLNDVDVFAQDLGFIAIIEGDALVG
HHHHCCCHHCCCCCCCCCCCCCCCCHHHCCEEECCCCCHHHHHHHCCCEEEEEECCEEEE
FNVSVGGGMGATHGDAATYPRLADVVGFIPPEQTLAVAEEVVKIHRDFGDRTNRKHARLK
EEEEECCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
YVLEERGVPWFTAELEKRLGFPLQPARPFAFEHNGDRFGWTEGHDGRWHLTLHLDSGRVA
HHHHHCCCCEEHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEEEEECCCCCC
DRPGAPHLTGLREIARIHTGDFRLTANQNLVIAGVTPEARDAIGALVTAHALDSFRSASP
CCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
VRRNALACVALPTCGLAMAEAERYLPTFVGRLEDRLRAHGLQDANLLLRITGCPNGCARP
HHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
YLAEVGLVGKAPGRYNLHLGGDARGQRLSHLYRENIDEDAILAALEPLFEGYARERQPGE
HHHHCCCEECCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GFGDFVVRAGHVPSPAVQPRPS
CCHHHHEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA