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The map label for this gene is yajO [H]

Identifier: 108763103

GI number: 108763103

Start: 452250

End: 453227

Strand: Reverse

Name: yajO [H]

Synonym: MXAN_0391

Alternate gene names: 108763103

Gene position: 453227-452250 (Counterclockwise)

Preceding gene: 108760688

Following gene: 108758203

Centisome position: 4.96

GC content: 67.79

Gene sequence:

>978_bases
ATGCCCCAGACGAAGCTCGAAGCACGCAAGGCACTCGGAACCACGGGCCTTCAGGTATCCCCCCTGTGCCTGGGAGGGAA
CGTCTTCGGTTGGACAGCCGACGAGGCGACCTCGTTCGCGGTGCTCGATGCCTTCGTCGACAACGGCGGCAACTTCATCG
ACACAGCTGACGTCTATTCGAGCTGGGTCCCCGGCAACCGCGGCGGCGAGTCGGAGACGCTCATCGGCAAGTGGCTGAAG
TCGCGCGGCGCTCGGGAGCGCGTCGTCATCGCCACCAAGGTGGGCTCGCAAACAGAGCTGGGGAAGGGCCTGGGCCGCGA
GCACATCCAGCGCAGCGTGGAGGCCTCGCTGCGCCGGTTGCAGGTGGACGTCATCGACCTCTACTACGCGCACTACGAGG
ACCTGGACACGCCAGTGGAGGAGACGATGGCGGCCTTCGACGCGCTGGTGCGCGCCGGCAAGGTCCGCGCACTGGGCACC
AGCAACCACTCCCCGCAGCGGCTCACCGAGTCGCTGGAGGTGTCCCGCCGCAACAACCTCGCCCGGTACGCGGTGCTGCA
ACCGCACTACAACCTCGTCGAGCGCAAGGACTTCGAGTCATCGCTCCGGGGCATCTGCGAACGGGAAGGGCTCGTGGTGG
CGCCCTACTTCGCGTTGGCCTCGGGCTTCCTGACGGGCAAGTACCGCAAGGACCAGCCACCTCCGAAGTCGGCCCGCGCC
GAAGGCGTGCTGAAGCAGTATGGAAACGCGCGAGGCTGGGCGGTGATTGATGCCCTGGAGGCCGTAACGCGCCGGCATCC
GGGAGCGAACTTCGCCCAGGTCGCGCTCGCGTGGCTCGCGGCTCAGCCCACCATCGTGGCGCCCATCGCGAGCGCGACGT
CCGCCAGCCAGACACAGGAACTGCTGGGTGCGTTCACGTTGCAACTGACGGAGGAGGACCTCCGCGCCCTGGACGTTGCG
TCGTCCCGCGAGGCCTGA

Upstream 100 bases:

>100_bases
CCGATGAACGGGGCATTTTGACCTGCACCCTGCCTCGGGACGCGTTAGCTACGCCGGCCACGGCCCGCGGGCCGACCACT
CACCGAGGGAGCGACAGGCA

Downstream 100 bases:

>100_bases
GAAGGCTCGAAGCCCATGAGCACGTTCACCGACTTCAAAACGGCCGACCTCTGCGATGCCCACGCGGGCACGCCGCGGTT
CCAGATTGCCGAGCCCGGGT

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MPQTKLEARKALGTTGLQVSPLCLGGNVFGWTADEATSFAVLDAFVDNGGNFIDTADVYSSWVPGNRGGESETLIGKWLK
SRGARERVVIATKVGSQTELGKGLGREHIQRSVEASLRRLQVDVIDLYYAHYEDLDTPVEETMAAFDALVRAGKVRALGT
SNHSPQRLTESLEVSRRNNLARYAVLQPHYNLVERKDFESSLRGICEREGLVVAPYFALASGFLTGKYRKDQPPPKSARA
EGVLKQYGNARGWAVIDALEAVTRRHPGANFAQVALAWLAAQPTIVAPIASATSASQTQELLGAFTLQLTEEDLRALDVA
SSREA

Sequences:

>Translated_325_residues
MPQTKLEARKALGTTGLQVSPLCLGGNVFGWTADEATSFAVLDAFVDNGGNFIDTADVYSSWVPGNRGGESETLIGKWLK
SRGARERVVIATKVGSQTELGKGLGREHIQRSVEASLRRLQVDVIDLYYAHYEDLDTPVEETMAAFDALVRAGKVRALGT
SNHSPQRLTESLEVSRRNNLARYAVLQPHYNLVERKDFESSLRGICEREGLVVAPYFALASGFLTGKYRKDQPPPKSARA
EGVLKQYGNARGWAVIDALEAVTRRHPGANFAQVALAWLAAQPTIVAPIASATSASQTQELLGAFTLQLTEEDLRALDVA
SSREA
>Mature_324_residues
PQTKLEARKALGTTGLQVSPLCLGGNVFGWTADEATSFAVLDAFVDNGGNFIDTADVYSSWVPGNRGGESETLIGKWLKS
RGARERVVIATKVGSQTELGKGLGREHIQRSVEASLRRLQVDVIDLYYAHYEDLDTPVEETMAAFDALVRAGKVRALGTS
NHSPQRLTESLEVSRRNNLARYAVLQPHYNLVERKDFESSLRGICEREGLVVAPYFALASGFLTGKYRKDQPPPKSARAE
GVLKQYGNARGWAVIDALEAVTRRHPGANFAQVALAWLAAQPTIVAPIASATSASQTQELLGAFTLQLTEEDLRALDVAS
SREA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=315, Percent_Identity=31.4285714285714, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI27436969, Length=307, Percent_Identity=31.5960912052117, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI27436971, Length=324, Percent_Identity=30.8641975308642, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436964, Length=331, Percent_Identity=28.7009063444109, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436962, Length=326, Percent_Identity=28.5276073619632, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=28.3950617283951, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI223718702, Length=209, Percent_Identity=35.4066985645933, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI41152114, Length=274, Percent_Identity=33.5766423357664, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41327764, Length=310, Percent_Identity=32.258064516129, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI223718708, Length=184, Percent_Identity=35.3260869565217, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI87081735, Length=316, Percent_Identity=35.7594936708861, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1789199, Length=332, Percent_Identity=31.9277108433735, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=31.4024390243902, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789375, Length=322, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=29.2253521126761, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17550248, Length=328, Percent_Identity=25.3048780487805, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323998, Length=339, Percent_Identity=28.3185840707965, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=301, Percent_Identity=27.2425249169435, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319951, Length=326, Percent_Identity=25.7668711656442, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=27.5659824046921, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321052, Length=171, Percent_Identity=35.672514619883, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=24.4094488188976, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640980, Length=193, Percent_Identity=31.6062176165803, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45549126, Length=193, Percent_Identity=31.6062176165803, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646159, Length=202, Percent_Identity=31.6831683168317, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=180, Percent_Identity=35, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35329; Mature: 35198

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTKLEARKALGTTGLQVSPLCLGGNVFGWTADEATSFAVLDAFVDNGGNFIDTADVYS
CCCHHHHHHHHHCCCCCEECEEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHH
SWVPGNRGGESETLIGKWLKSRGARERVVIATKVGSQTELGKGLGREHIQRSVEASLRRL
HCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHH
QVDVIDLYYAHYEDLDTPVEETMAAFDALVRAGKVRALGTSNHSPQRLTESLEVSRRNNL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCC
ARYAVLQPHYNLVERKDFESSLRGICEREGLVVAPYFALASGFLTGKYRKDQPPPKSARA
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHH
EGVLKQYGNARGWAVIDALEAVTRRHPGANFAQVALAWLAAQPTIVAPIASATSASQTQE
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHCCCCHHHHHH
LLGAFTLQLTEEDLRALDVASSREA
HHHHHHHEECHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PQTKLEARKALGTTGLQVSPLCLGGNVFGWTADEATSFAVLDAFVDNGGNFIDTADVYS
CCHHHHHHHHHCCCCCEECEEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHH
SWVPGNRGGESETLIGKWLKSRGARERVVIATKVGSQTELGKGLGREHIQRSVEASLRRL
HCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHH
QVDVIDLYYAHYEDLDTPVEETMAAFDALVRAGKVRALGTSNHSPQRLTESLEVSRRNNL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCC
ARYAVLQPHYNLVERKDFESSLRGICEREGLVVAPYFALASGFLTGKYRKDQPPPKSARA
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHH
EGVLKQYGNARGWAVIDALEAVTRRHPGANFAQVALAWLAAQPTIVAPIASATSASQTQE
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHCCCCHHHHHH
LLGAFTLQLTEEDLRALDVASSREA
HHHHHHHEECHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]