Click here to switch to the map view.

The map label for this gene is pit [H]

Identifier: 108763086

GI number: 108763086

Start: 2647770

End: 2648795

Strand: Reverse

Name: pit [H]

Synonym: MXAN_2280

Alternate gene names: 108763086

Gene position: 2648795-2647770 (Counterclockwise)

Preceding gene: 108763879

Following gene: 108757768

Centisome position: 28.98

GC content: 67.25

Gene sequence:

>1026_bases
ATGCTACTCGCCGCCGTCATCCTCATTGTCGCGGTCGCACTCATCTTCGATTTCATCAATGGATTCCACGACGCGGCGAA
CTCCATCGCCACCGTGGTCTCCACCCGAGTGCTGTCCCCCAACCTCGCCGTGGCCTGGGCCGCGTTCTTCAACTTCGTGG
CGGCCTTTGGCGGGAACGTCCACGTGGCCAACACCATGGGCAAGGGCATCATCAACTTCGAGATGCTCCGGGCTCAGGGC
CCCAGCGCGGTGCTCGCCGTCATCTTCTCCGCCCTCATGGGCGCCATCGTCTGGAACCTGTTGACGTGGTGGTGGGGCCT
GCCCTCCTCGTCGTCGCACGCGCTGGCCGGAGGCATGATTGGCGCCACGCTGCCGGTGCTTGGCTTCGCGGGCCTGGTGG
GCTCGGGCATCGCGAAGATCGCCGCCTTCATCGTGCTGTCGCCGCTCATTGGCATGACGCTGGGCATCGGTCTGATGGTG
TTGAGCACGTGGGCGGTGCACCGCCAGACACCGCTGAAGGTGGACTCGTGGTTCCGCCGGCTGCAGCTCGTGTCGTCCGC
CATCTTCTCCTACAGCCACGGCACCAATGACGCGCAGAAGGTGATGGGCATCATCGCGGTGGTGCTCTTCGGCACCATCT
GGCAGGACCGGCCGTTCCACATCGACTGGTGGATGATCATCTCCTGCCACGCGGCCATCGCCCTGGGGACCTTCTTCGGC
GGGTGGCGCATCGTCCGCACCATGGGCCACAGCCTCACCAAGCTGGCGCCCATCGGCGGCTTCGCCGCGGAGACGGGCGG
CGGCGTCACCATCATCGCGCTGGCCCAACTGGGCATCCCCGTGTCCACCACGCACACCATCACCGGCGCCATCGTCGGCG
TGGGCGCCACCCGGGGCTGGCGCGCGGTGAAGTGGGGCGTCGCCGGCCGCATCATCTGGGCCTGGGTGGTCACCATCCCG
GCCGCGGCGCTGACCGCGGTGGTCTTCTACGGACTCACCCAGGTGGTCATGCGCCTGGCAAGCTGA

Upstream 100 bases:

>100_bases
CATCAAGTGGAAGGAGATTTACGACTTCATTGAGACCGCCACCGACAAGTGCCAGTCGGTGGCGAACGTCATCGAAGGCG
TGGTGCTGGAGCACAGCTAA

Downstream 100 bases:

>100_bases
GCGCTGGGGAGGGCTCGCATTGACCTCCGCGAGCCCTTCCCCGTCATGCATGGACCTGCCGGGTCCCCTGCTTGACTTGC
CGCGGCAAGTTCGGCCAGCC

Product: phosphate transporter family protein

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLLAAVILIVAVALIFDFINGFHDAANSIATVVSTRVLSPNLAVAWAAFFNFVAAFGGNVHVANTMGKGIINFEMLRAQG
PSAVLAVIFSALMGAIVWNLLTWWWGLPSSSSHALAGGMIGATLPVLGFAGLVGSGIAKIAAFIVLSPLIGMTLGIGLMV
LSTWAVHRQTPLKVDSWFRRLQLVSSAIFSYSHGTNDAQKVMGIIAVVLFGTIWQDRPFHIDWWMIISCHAAIALGTFFG
GWRIVRTMGHSLTKLAPIGGFAAETGGGVTIIALAQLGIPVSTTHTITGAIVGVGATRGWRAVKWGVAGRIIWAWVVTIP
AAALTAVVFYGLTQVVMRLAS

Sequences:

>Translated_341_residues
MLLAAVILIVAVALIFDFINGFHDAANSIATVVSTRVLSPNLAVAWAAFFNFVAAFGGNVHVANTMGKGIINFEMLRAQG
PSAVLAVIFSALMGAIVWNLLTWWWGLPSSSSHALAGGMIGATLPVLGFAGLVGSGIAKIAAFIVLSPLIGMTLGIGLMV
LSTWAVHRQTPLKVDSWFRRLQLVSSAIFSYSHGTNDAQKVMGIIAVVLFGTIWQDRPFHIDWWMIISCHAAIALGTFFG
GWRIVRTMGHSLTKLAPIGGFAAETGGGVTIIALAQLGIPVSTTHTITGAIVGVGATRGWRAVKWGVAGRIIWAWVVTIP
AAALTAVVFYGLTQVVMRLAS
>Mature_341_residues
MLLAAVILIVAVALIFDFINGFHDAANSIATVVSTRVLSPNLAVAWAAFFNFVAAFGGNVHVANTMGKGIINFEMLRAQG
PSAVLAVIFSALMGAIVWNLLTWWWGLPSSSSHALAGGMIGATLPVLGFAGLVGSGIAKIAAFIVLSPLIGMTLGIGLMV
LSTWAVHRQTPLKVDSWFRRLQLVSSAIFSYSHGTNDAQKVMGIIAVVLFGTIWQDRPFHIDWWMIISCHAAIALGTFFG
GWRIVRTMGHSLTKLAPIGGFAAETGGGVTIIALAQLGIPVSTTHTITGAIVGVGATRGWRAVKWGVAGRIIWAWVVTIP
AAALTAVVFYGLTQVVMRLAS

Specific function: Low-affinity inorganic phosphate transport (Probable) [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=186, Percent_Identity=30.6451612903226, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI5803173, Length=168, Percent_Identity=31.547619047619, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789360, Length=222, Percent_Identity=36.9369369369369, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789907, Length=219, Percent_Identity=36.0730593607306, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17539280, Length=149, Percent_Identity=30.8724832214765, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146401, Length=159, Percent_Identity=27.0440251572327, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71981576, Length=154, Percent_Identity=26.6233766233766, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566716, Length=156, Percent_Identity=29.4871794871795, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536725, Length=174, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17557328, Length=150, Percent_Identity=29.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319773, Length=170, Percent_Identity=28.8235294117647, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356511, Length=186, Percent_Identity=27.9569892473118, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 35973; Mature: 35973

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAAVILIVAVALIFDFINGFHDAANSIATVVSTRVLSPNLAVAWAAFFNFVAAFGGNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCE
HVANTMGKGIINFEMLRAQGPSAVLAVIFSALMGAIVWNLLTWWWGLPSSSSHALAGGMI
EEEHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
GATLPVLGFAGLVGSGIAKIAAFIVLSPLIGMTLGIGLMVLSTWAVHRQTPLKVDSWFRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LQLVSSAIFSYSHGTNDAQKVMGIIAVVLFGTIWQDRPFHIDWWMIISCHAAIALGTFFG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHH
GWRIVRTMGHSLTKLAPIGGFAAETGGGVTIIALAQLGIPVSTTHTITGAIVGVGATRGW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCCCCCCCHHHHHHHEECCCCCCC
RAVKWGVAGRIIWAWVVTIPAAALTAVVFYGLTQVVMRLAS
HHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLAAVILIVAVALIFDFINGFHDAANSIATVVSTRVLSPNLAVAWAAFFNFVAAFGGNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCE
HVANTMGKGIINFEMLRAQGPSAVLAVIFSALMGAIVWNLLTWWWGLPSSSSHALAGGMI
EEEHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
GATLPVLGFAGLVGSGIAKIAAFIVLSPLIGMTLGIGLMVLSTWAVHRQTPLKVDSWFRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LQLVSSAIFSYSHGTNDAQKVMGIIAVVLFGTIWQDRPFHIDWWMIISCHAAIALGTFFG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHH
GWRIVRTMGHSLTKLAPIGGFAAETGGGVTIIALAQLGIPVSTTHTITGAIVGVGATRGW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCCCCCCCHHHHHHHEECCCCCCC
RAVKWGVAGRIIWAWVVTIPAAALTAVVFYGLTQVVMRLAS
HHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9696772; 11481430 [H]