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The map label for this gene is macB [H]

Identifier: 108763012

GI number: 108763012

Start: 5124436

End: 5125674

Strand: Reverse

Name: macB [H]

Synonym: MXAN_4173

Alternate gene names: 108763012

Gene position: 5125674-5124436 (Counterclockwise)

Preceding gene: 108756984

Following gene: 108760958

Centisome position: 56.08

GC content: 67.31

Gene sequence:

>1239_bases
ATGAGCCAGCGGTCCGCCTTCCGCGTGGATGTGCTGGAGGGCGCACGCATCGCGGTCTTCTCCCTGAAGGCCAACCGCCT
GCGCACGGTGCTGACCACCCTGGGCATTGGCATCGGCGTGGCCACGCTGCTGGCCATCGTCGGCATCATCCAGGGGCTCA
ACACGTCCTTCCACAAGCAGTTGGCCACCTTCGGGGCGAACACGATGTACGTGTCCAAGTGGCCCTGGATGATCAAGGGC
GACTGGTGGAAGTACCGCAACCGGAAGAACTTCACCCTGGAGCAGATGCAGCGGCTGCGCACGCTGGCGCCCTTCGTGAC
GGCCATGTCCCCGGCGGTGTCTCGCCTGTCGGACGTGGCGCATGGCGGCGAGCAGATGTCCACCGTGCGCATCCAGGGCG
TGACGCACGAGTACCTCAACATCTCTGGCTACGAAATCACCGGCGGGCGCTTCCTCACCGAGGCGGACGACGCGACGACG
CGGCCGGTGGCGGTGGTGGGCGCGGACGTGGTGGACGGGCTCTTCCCGGGCGTCAGTCCGGTGGGGCAGTCGATTCGCAT
CGACAACCGCACCTTCCAGGTGGTGGGCACGCTCAGCCGCAAGGGGAAGATGGTGGGGGAGAGCATGGACCTGCTCGTCT
TCATCCCCTTCAAGACGTTCTATTCGAGCTTCGGCAAGGGCCGCAGTTTCGAGATTGCCATGGCGGTGGAGGATGCCTCG
CAGATGCGGTCCGCGGAGGACCAGCTCACCGGCATCATGCGGCGCGTGCGCTCCACGCCTCCGGGGGCGGAGGACGACTT
CTCCATCAACCGGCCAGAGGCCATGGCGCAGACATACGAGCAGCTCACGGGCGCGTTGTACGGCGTGGCCGTGGGCGTGG
GGCTCATCACGTTGCTGGTGGGCGGTATCGGCATCATGAACATCATGCTGGTGTCGGTGCGCGAGCGGACGCGGGAGATT
GGCGTGCGGCGTGCGCTGGGCGCCCGGAAACGGACCATCGTCTTCCAGTTCCTGATGGAAGCCTCGAGCGTGTCCGCGGT
GGGAGGCCTGCTGGGGACGACCGTGGGATTGGGCACGGCCAAGGTGGTGTCGCTCATCACGCCGCTCGCGGCGGACGTGC
AGCCGATGACCGTGGTGGCGGGGGTGGGCTTCGCCGCGCTGGTGGGCCTGCTGTTCGGCATCTGGCCGGCGGCGCGCGCG
GCGAACCTGGACCCCGTGGAAGCCCTTCGTTACGAGTAG

Upstream 100 bases:

>100_bases
CCCGGGCCATCCGCCTGAGCGACGGAGAGATTGTCGCGGACGGTGACGGCCGCACGGTGGCCATGGGAACGGCGACGGAC
GTACTGAACGCGGGGGGCGC

Downstream 100 bases:

>100_bases
CGCGATGCGAGCGTTCCTGGACAATTTGCGGTTGGCGTTGGGCACCTTCCTGGGCAACCCGCTGCGCTCGCTGTTGACGC
TGCTGGGCATCGTCATTGGC

Product: putative ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSQRSAFRVDVLEGARIAVFSLKANRLRTVLTTLGIGIGVATLLAIVGIIQGLNTSFHKQLATFGANTMYVSKWPWMIKG
DWWKYRNRKNFTLEQMQRLRTLAPFVTAMSPAVSRLSDVAHGGEQMSTVRIQGVTHEYLNISGYEITGGRFLTEADDATT
RPVAVVGADVVDGLFPGVSPVGQSIRIDNRTFQVVGTLSRKGKMVGESMDLLVFIPFKTFYSSFGKGRSFEIAMAVEDAS
QMRSAEDQLTGIMRRVRSTPPGAEDDFSINRPEAMAQTYEQLTGALYGVAVGVGLITLLVGGIGIMNIMLVSVRERTREI
GVRRALGARKRTIVFQFLMEASSVSAVGGLLGTTVGLGTAKVVSLITPLAADVQPMTVVAGVGFAALVGLLFGIWPAARA
ANLDPVEALRYE

Sequences:

>Translated_412_residues
MSQRSAFRVDVLEGARIAVFSLKANRLRTVLTTLGIGIGVATLLAIVGIIQGLNTSFHKQLATFGANTMYVSKWPWMIKG
DWWKYRNRKNFTLEQMQRLRTLAPFVTAMSPAVSRLSDVAHGGEQMSTVRIQGVTHEYLNISGYEITGGRFLTEADDATT
RPVAVVGADVVDGLFPGVSPVGQSIRIDNRTFQVVGTLSRKGKMVGESMDLLVFIPFKTFYSSFGKGRSFEIAMAVEDAS
QMRSAEDQLTGIMRRVRSTPPGAEDDFSINRPEAMAQTYEQLTGALYGVAVGVGLITLLVGGIGIMNIMLVSVRERTREI
GVRRALGARKRTIVFQFLMEASSVSAVGGLLGTTVGLGTAKVVSLITPLAADVQPMTVVAGVGFAALVGLLFGIWPAARA
ANLDPVEALRYE
>Mature_411_residues
SQRSAFRVDVLEGARIAVFSLKANRLRTVLTTLGIGIGVATLLAIVGIIQGLNTSFHKQLATFGANTMYVSKWPWMIKGD
WWKYRNRKNFTLEQMQRLRTLAPFVTAMSPAVSRLSDVAHGGEQMSTVRIQGVTHEYLNISGYEITGGRFLTEADDATTR
PVAVVGADVVDGLFPGVSPVGQSIRIDNRTFQVVGTLSRKGKMVGESMDLLVFIPFKTFYSSFGKGRSFEIAMAVEDASQ
MRSAEDQLTGIMRRVRSTPPGAEDDFSINRPEAMAQTYEQLTGALYGVAVGVGLITLLVGGIGIMNIMLVSVRERTREIG
VRRALGARKRTIVFQFLMEASSVSAVGGLLGTTVGLGTAKVVSLITPLAADVQPMTVVAGVGFAALVGLLFGIWPAARAA
NLDPVEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=403, Percent_Identity=33.2506203473945, Blast_Score=155, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44487; Mature: 44356

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRSAFRVDVLEGARIAVFSLKANRLRTVLTTLGIGIGVATLLAIVGIIQGLNTSFHKQ
CCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LATFGANTMYVSKWPWMIKGDWWKYRNRKNFTLEQMQRLRTLAPFVTAMSPAVSRLSDVA
HHHHCCCEEEEECCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGGEQMSTVRIQGVTHEYLNISGYEITGGRFLTEADDATTRPVAVVGADVVDGLFPGVSP
CCCCCEEEEEEECCEEHHCCCCCEEEECCEEEECCCCCCCCCEEEECHHHHHHHCCCCCC
VGQSIRIDNRTFQVVGTLSRKGKMVGESMDLLVFIPFKTFYSSFGKGRSFEIAMAVEDAS
CCCCEEECCCEEEEEEEHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEEHHHH
QMRSAEDQLTGIMRRVRSTPPGAEDDFSINRPEAMAQTYEQLTGALYGVAVGVGLITLLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGIMNIMLVSVRERTREIGVRRALGARKRTIVFQFLMEASSVSAVGGLLGTTVGLGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KVVSLITPLAADVQPMTVVAGVGFAALVGLLFGIWPAARAANLDPVEALRYE
HHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure 
SQRSAFRVDVLEGARIAVFSLKANRLRTVLTTLGIGIGVATLLAIVGIIQGLNTSFHKQ
CCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LATFGANTMYVSKWPWMIKGDWWKYRNRKNFTLEQMQRLRTLAPFVTAMSPAVSRLSDVA
HHHHCCCEEEEECCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGGEQMSTVRIQGVTHEYLNISGYEITGGRFLTEADDATTRPVAVVGADVVDGLFPGVSP
CCCCCEEEEEEECCEEHHCCCCCEEEECCEEEECCCCCCCCCEEEECHHHHHHHCCCCCC
VGQSIRIDNRTFQVVGTLSRKGKMVGESMDLLVFIPFKTFYSSFGKGRSFEIAMAVEDAS
CCCCEEECCCEEEEEEEHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEEHHHH
QMRSAEDQLTGIMRRVRSTPPGAEDDFSINRPEAMAQTYEQLTGALYGVAVGVGLITLLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGIMNIMLVSVRERTREIGVRRALGARKRTIVFQFLMEASSVSAVGGLLGTTVGLGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KVVSLITPLAADVQPMTVVAGVGFAALVGLLFGIWPAARAANLDPVEALRYE
HHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA