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The map label for this gene is rnhB

Identifier: 108762969

GI number: 108762969

Start: 2994879

End: 2995760

Strand: Reverse

Name: rnhB

Synonym: MXAN_2574

Alternate gene names: 108762969

Gene position: 2995760-2994879 (Counterclockwise)

Preceding gene: 108759345

Following gene: 108761516

Centisome position: 32.78

GC content: 70.07

Gene sequence:

>882_bases
ATGTCCGCAGACACGGTGGAACAGTTGCTTCAGTGCGCGCTGTCCGAGCTGACCGCGCGCTTCGTCACCCAGGCCACCCC
CGTCCCCACCGGCTTGCTGGAGGCGTTGGACGCGGACCCGCGCGCGGGCGCTCATGCGCTCGCCCGGCGCATCCGTTCGC
GCCAGGAGAAGAACCGCGCGGAGGGCCAGCGCATGCGCAAGCTGCTCCGTTTCGAGACGGAGCTCTGGGAGCAGGGCCAC
ACGCACATCGCGGGTGTGGACGAGGCGGGCATGGCGCCCCTGGCGGGGCCCGTCGTGGCCGCCGCGGCCGTGCTGCCCAA
GGGTTTCCGGCTCAAGGGGCTGGATGACTCGAAGAAGATTCTCGACGCCGAGAAGCGCGAGTCGCTGGCCGAGGCCATCA
AGCGCGACGCGGTGGCATGGGCCGTGGGCCGCGCGGAGGTGGAGGAAATCGACCGCATCAACATCTACCACGCGGGCCTG
CTGGCCATGCGCCGCGCGGTGGAGGGGCTGTCGGTGAAGCCGGACCACCTGCTGGTGGATGCTCGCACGGTGCCGGAGTG
CTCGGTGCCGCAGAAGGGCATCATCAAGGGGGACGCACTGTCTCTCAGCATCGCAGCGGCCTCCATCCTGGCGAAGACGA
CGCGCGACCGTTGGATGGCGGAGCTGGATGACCAGTACCCGGGTTATGGGCTCGCCGCGCACAAGGGCTACCCGACGCCG
CACCACCTGCAGGTGCTGCGTGAAAAGGGCGTGCTGCCCATCCACCGACGCAGCTTCGCGCCGGTGCGCGAGGCCCTGGG
CCTGCCGACCGGCTCACCGCCTTCCGCCCTCCAGGCGGAGCTGTTCCCCGAGGCCCCTTCCCGAACAGGGGTGAAGTCAT
GA

Upstream 100 bases:

>100_bases
CTCCGAGCACGGGGCCGCGGGGATGTGTTGCCGCGGTGTGCGCGTTCCCCGCGCAAGGGGTCCTGTCAGCCCACGTTCCA
GGTAGGTCCGGGCCCTCATC

Downstream 100 bases:

>100_bases
GCGCCGACCGGGACATCGACGAGTGGATGGCCGCGCGAGGCATCACCCTGCCCGAGGCCCGCGCTCGCACCCGCGCGGTG
CTGGAGGAAGTGGGCCTCAC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSADTVEQLLQCALSELTARFVTQATPVPTGLLEALDADPRAGAHALARRIRSRQEKNRAEGQRMRKLLRFETELWEQGH
THIAGVDEAGMAPLAGPVVAAAAVLPKGFRLKGLDDSKKILDAEKRESLAEAIKRDAVAWAVGRAEVEEIDRINIYHAGL
LAMRRAVEGLSVKPDHLLVDARTVPECSVPQKGIIKGDALSLSIAAASILAKTTRDRWMAELDDQYPGYGLAAHKGYPTP
HHLQVLREKGVLPIHRRSFAPVREALGLPTGSPPSALQAELFPEAPSRTGVKS

Sequences:

>Translated_293_residues
MSADTVEQLLQCALSELTARFVTQATPVPTGLLEALDADPRAGAHALARRIRSRQEKNRAEGQRMRKLLRFETELWEQGH
THIAGVDEAGMAPLAGPVVAAAAVLPKGFRLKGLDDSKKILDAEKRESLAEAIKRDAVAWAVGRAEVEEIDRINIYHAGL
LAMRRAVEGLSVKPDHLLVDARTVPECSVPQKGIIKGDALSLSIAAASILAKTTRDRWMAELDDQYPGYGLAAHKGYPTP
HHLQVLREKGVLPIHRRSFAPVREALGLPTGSPPSALQAELFPEAPSRTGVKS
>Mature_292_residues
SADTVEQLLQCALSELTARFVTQATPVPTGLLEALDADPRAGAHALARRIRSRQEKNRAEGQRMRKLLRFETELWEQGHT
HIAGVDEAGMAPLAGPVVAAAAVLPKGFRLKGLDDSKKILDAEKRESLAEAIKRDAVAWAVGRAEVEEIDRINIYHAGLL
AMRRAVEGLSVKPDHLLVDARTVPECSVPQKGIIKGDALSLSIAAASILAKTTRDRWMAELDDQYPGYGLAAHKGYPTPH
HLQVLREKGVLPIHRRSFAPVREALGLPTGSPPSALQAELFPEAPSRTGVKS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=190, Percent_Identity=51.5789473684211, Blast_Score=183, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_MYXXD (Q1D980)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_630793.1
- ProteinModelPortal:   Q1D980
- SMR:   Q1D980
- STRING:   Q1D980
- GeneID:   4106723
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_2574
- TIGR:   MXAN_2574
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RINIYHA
- PhylomeDB:   Q1D980
- ProtClustDB:   PRK00015
- BioCyc:   MXAN246197:MXAN_2574-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 31775; Mature: 31644

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADTVEQLLQCALSELTARFVTQATPVPTGLLEALDADPRAGAHALARRIRSRQEKNRA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EGQRMRKLLRFETELWEQGHTHIAGVDEAGMAPLAGPVVAAAAVLPKGFRLKGLDDSKKI
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCHHHH
LDAEKRESLAEAIKRDAVAWAVGRAEVEEIDRINIYHAGLLAMRRAVEGLSVKPDHLLVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ARTVPECSVPQKGIIKGDALSLSIAAASILAKTTRDRWMAELDDQYPGYGLAAHKGYPTP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCH
HHLQVLREKGVLPIHRRSFAPVREALGLPTGSPPSALQAELFPEAPSRTGVKS
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SADTVEQLLQCALSELTARFVTQATPVPTGLLEALDADPRAGAHALARRIRSRQEKNRA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EGQRMRKLLRFETELWEQGHTHIAGVDEAGMAPLAGPVVAAAAVLPKGFRLKGLDDSKKI
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCHHHH
LDAEKRESLAEAIKRDAVAWAVGRAEVEEIDRINIYHAGLLAMRRAVEGLSVKPDHLLVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ARTVPECSVPQKGIIKGDALSLSIAAASILAKTTRDRWMAELDDQYPGYGLAAHKGYPTP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCH
HHLQVLREKGVLPIHRRSFAPVREALGLPTGSPPSALQAELFPEAPSRTGVKS
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA