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The map label for this gene is fabD [H]

Identifier: 108762809

GI number: 108762809

Start: 5971044

End: 5971985

Strand: Reverse

Name: fabD [H]

Synonym: MXAN_4771

Alternate gene names: 108762809

Gene position: 5971985-5971044 (Counterclockwise)

Preceding gene: 108758340

Following gene: 108763318

Centisome position: 65.34

GC content: 71.87

Gene sequence:

>942_bases
ATGTCGAAGGTCGCGTTCGTGTTCCCCGGGCAAGGCAGCCAGGCCGTGGGGATGGGCAAGGACCTGTATGAGAAGTTCCC
CGAGGCCCGGGCCGTGTTCGACGCGGTTGATGCCGCCCTGGGGGAGAAGCTCTCCACCCTCTGTTTCGAGGGCCCGGACG
AGGCGCTGAAGCTCACGGCCAACACCCAGCCGGCCATCCTCACGGTGTCGCTGGCGGCGCACGCGGTGTTCGCGAAGCGG
GGACCGGCGCCGTCCTTCGTGGCGGGGCACTCGCTGGGCGAGTACTCGGCGCTGGTGGCGGCGGGCGCCATGGACCTGGG
CGACGCGGTCCGGGTGGTGCGCGCGCGCGGCACCTTCATGCAGGAGGCGGTGCCCGCGGGCGTGGGCGCCATGGCCGCGG
TGCTGGGCCTGGTTCCGGAGAAGGTGAAGGCGGCCTGTGACGCGGCGGCCGAGGGGCAGGTGGTGTCGCCGGCGAACTAC
AACTCGCCCGAGCAGACGGTCATCGCCGGTGACGCGGCGGCCGTGGAGCGCGCCGGGGTGAAGTGCAAGGAGGCCGGCGC
CAAGCGCGTGATGCCCCTGCCGGTATCCGCCCCCTTCCACTGCGCGCTGATGGCGCCGGTGCAGCCCCGGCTGGCGGAGG
TGCTGGGCGGCATCCAGGTGTCCGCGCCGTCCGTGCCGGTGGTGACCAACGTGGAGGCCCGTCCCAACGCGGACGCGTCG
CGGGTGGTGCCGCTGCTCCTGGAGCAGGTGAGCTCGCCGGTGCGCTGGATTGAGTGCGTGGAGGCGCTGAAGGCCGAAGG
CGTCACCCGCATCATCGAGCTGGGGCCGGGCAAGGTGCTGGTGGGCCTGGTCAAGCGCATCACCAAGGACATCGAGCTGT
TCAACGTCGAGGACTCCGCGAGCCTGGACAAGGCGCTCGCGGCACTGGGGGTGGCAGCATGA

Upstream 100 bases:

>100_bases
GGCGGGGCGCCTCGCGGAAATTGCTGGCTCAACCTGGTCAGGTACGGCAACAGGGCGTCCAGCCTGCGGCCCCGGCCGCT
GAAGAGGAGGCAGAGTCCGC

Downstream 100 bases:

>100_bases
GCGGCTTCAAGGACAAGGTCGTGCTCGTGACGGGTGGCTCGCGCGGCATCGGCCGGGCGTGCGCGGTGGCCTTCGCCAAG
GCGGGGGCCTCCACCGTGGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSKVAFVFPGQGSQAVGMGKDLYEKFPEARAVFDAVDAALGEKLSTLCFEGPDEALKLTANTQPAILTVSLAAHAVFAKR
GPAPSFVAGHSLGEYSALVAAGAMDLGDAVRVVRARGTFMQEAVPAGVGAMAAVLGLVPEKVKAACDAAAEGQVVSPANY
NSPEQTVIAGDAAAVERAGVKCKEAGAKRVMPLPVSAPFHCALMAPVQPRLAEVLGGIQVSAPSVPVVTNVEARPNADAS
RVVPLLLEQVSSPVRWIECVEALKAEGVTRIIELGPGKVLVGLVKRITKDIELFNVEDSASLDKALAALGVAA

Sequences:

>Translated_313_residues
MSKVAFVFPGQGSQAVGMGKDLYEKFPEARAVFDAVDAALGEKLSTLCFEGPDEALKLTANTQPAILTVSLAAHAVFAKR
GPAPSFVAGHSLGEYSALVAAGAMDLGDAVRVVRARGTFMQEAVPAGVGAMAAVLGLVPEKVKAACDAAAEGQVVSPANY
NSPEQTVIAGDAAAVERAGVKCKEAGAKRVMPLPVSAPFHCALMAPVQPRLAEVLGGIQVSAPSVPVVTNVEARPNADAS
RVVPLLLEQVSSPVRWIECVEALKAEGVTRIIELGPGKVLVGLVKRITKDIELFNVEDSASLDKALAALGVAA
>Mature_312_residues
SKVAFVFPGQGSQAVGMGKDLYEKFPEARAVFDAVDAALGEKLSTLCFEGPDEALKLTANTQPAILTVSLAAHAVFAKRG
PAPSFVAGHSLGEYSALVAAGAMDLGDAVRVVRARGTFMQEAVPAGVGAMAAVLGLVPEKVKAACDAAAEGQVVSPANYN
SPEQTVIAGDAAAVERAGVKCKEAGAKRVMPLPVSAPFHCALMAPVQPRLAEVLGGIQVSAPSVPVVTNVEARPNADASR
VVPLLLEQVSSPVRWIECVEALKAEGVTRIIELGPGKVLVGLVKRITKDIELFNVEDSASLDKALAALGVAA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=298, Percent_Identity=35.2348993288591, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI27477045, Length=113, Percent_Identity=42.4778761061947, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=51.4657980456026, Blast_Score=279, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=30.6122448979592, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=300, Percent_Identity=31, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI212642053, Length=332, Percent_Identity=27.710843373494, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24665753, Length=299, Percent_Identity=33.7792642140468, Blast_Score=151, Evalue=6e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32154; Mature: 32022

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVAFVFPGQGSQAVGMGKDLYEKFPEARAVFDAVDAALGEKLSTLCFEGPDEALKLTA
CCCEEEEECCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
NTQPAILTVSLAAHAVFAKRGPAPSFVAGHSLGEYSALVAAGAMDLGDAVRVVRARGTFM
CCCCEEEEEHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCHHH
QEAVPAGVGAMAAVLGLVPEKVKAACDAAAEGQVVSPANYNSPEQTVIAGDAAAVERAGV
HHHHCCCHHHHHHHHHHCHHHHHHHHCCCCCCCEECCCCCCCCCCEEEECCHHHHHHHCC
KCKEAGAKRVMPLPVSAPFHCALMAPVQPRLAEVLGGIQVSAPSVPVVTNVEARPNADAS
CHHHCCCCCEEECCCCCCCCEEEECCCCHHHHHHHCCCEECCCCCCEEECCCCCCCCCHH
RVVPLLLEQVSSPVRWIECVEALKAEGVTRIIELGPGKVLVGLVKRITKDIELFNVEDSA
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHEEEECCCHH
SLDKALAALGVAA
HHHHHHHHHHCCC
>Mature Secondary Structure 
SKVAFVFPGQGSQAVGMGKDLYEKFPEARAVFDAVDAALGEKLSTLCFEGPDEALKLTA
CCEEEEECCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
NTQPAILTVSLAAHAVFAKRGPAPSFVAGHSLGEYSALVAAGAMDLGDAVRVVRARGTFM
CCCCEEEEEHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCHHH
QEAVPAGVGAMAAVLGLVPEKVKAACDAAAEGQVVSPANYNSPEQTVIAGDAAAVERAGV
HHHHCCCHHHHHHHHHHCHHHHHHHHCCCCCCCEECCCCCCCCCCEEEECCHHHHHHHCC
KCKEAGAKRVMPLPVSAPFHCALMAPVQPRLAEVLGGIQVSAPSVPVVTNVEARPNADAS
CHHHCCCCCEEECCCCCCCCEEEECCCCHHHHHHHCCCEECCCCCCEEECCCCCCCCCHH
RVVPLLLEQVSSPVRWIECVEALKAEGVTRIIELGPGKVLVGLVKRITKDIELFNVEDSA
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHEEEECCCHH
SLDKALAALGVAA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]