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The map label for this gene is hutU [H]

Identifier: 108762714

GI number: 108762714

Start: 5347868

End: 5349523

Strand: Direct

Name: hutU [H]

Synonym: MXAN_4343

Alternate gene names: 108762714

Gene position: 5347868-5349523 (Clockwise)

Preceding gene: 108759078

Following gene: 108757377

Centisome position: 58.51

GC content: 69.99

Gene sequence:

>1656_bases
ATGTCCCGCGTCATCCGCGCCCCCCACGGTTCCACCCTGTCCTGCAAGGGCTGGGTCCAGGAGGCCGCGCTCCGGATGTT
GATGAACAACCTCGACCCGGACGTCGCCGAGCGCCCCGAGGACCTCGTCGTCTACGGCGGCACCGGCAAGGCCGCCCGCG
ACTGGCCCTCCTTCGACCGCATCGTGTCGAGCCTCCAGAACCTGGGCGACGATGAGACCCTGCTCGTCCAGTCCGGCAAG
CCCGTGGGCATCTTCCGCACGCACCCGGACGCGCCGCGCGTGCTCATCGCCAACTCCAACCTCGTGGGCCGCTGGGCCAA
CTGGGAGCATTTTCACGAGCTGGAGAAGAAGGGCCTGATGATGTACGGCCAGATGACCGCGGGCTCGTGGATCTACATCG
GCACGCAGGGCATCCTCCAGGGCACCTACGAGACCTTCGCCGCCGCCGGCCGCTTCCACTTCGGCACCGACGACCTGGCG
GGCCGCCTCATCCTCTCCGGCGGTCTGGGTGGCATGGGTGGCGCGCAGCCGCTGGCCGCCACCATGAACAACGCGGTGTT
CCTCGGCGTGGAGATCGACCCCACGCGCGCTCGCCGCCGCGTGGAGACGCGCTACCTGGACGTCGTCGCCAAGGACCTGG
ATGAGGCGCTGGCCCTGGTGAAGGACGCCCAGGAGAAGCGCGTGGGCCGCTCCATCGCCGTCATCGGCAACGCGGCGTCG
GTGTTCCGCGAGCTGTACCGCCGTGGCATCAAGCCGGACCTCGTCACGGACCAGACGAGCGCCCATGACCCGCTCAACGG
CTACATCCCCACGGACCTGTCGCTGGAGGCCGCCGCCGAGCTGCGCCAGCGGGATCCGGAGACGTACGTCCGCCGCGCGC
GCGAGTCGATGATGATGCACGTGCAGGCGATGAACGACTTCCAGAAGGCCGGCAGCCACGTCTTCGACTACGGCAACAAC
CTGCGCGGCCAGGCGGAGCTGGGCGGCATGGAGAACGCCTTCGAGTTCCCCGGCTTCGTCCCCGCCTACATCCGTCCCCT
CTTCTGCGAGGGCATGGGGCCCTTCCGCTGGGTGGCGCTCTCGGGTGACCCGGAGGACATCCGCGTCACCGACCGCGTGG
TGCGCGAGCTGTTCCCCCAGAAGGCCTCGCTCCAGCGCTGGCTGAACATGGCCGAGGAGCGCGTGGCGTTCCAGGGCCTG
CCCTCGCGCATCTGCTGGCTGGGGTATGGCGAGCGCGCCAAGGCGGGCCTCGCGTTCAACGAGCTGGTGCGCAAGGGCGA
GGTGAAGGCGCCCATCGTCATCGGCCGGGACCACCTGGACTGCGGCTCGGTGGCATCGCCCAACCGCGAGACGGAGGCGA
TGAAGGACGGCACGGACGCGGTGGCGGACTGGCCCATCCTCAACGCGCTGGTGAACGCGGTGAACGGCGCGTCGTGGGTG
TCCTTCCACCACGGCGGCGGCGTGGGCATGGGCTACTCGCTGCACGCCGGTCAGGTCATCGTCGCGGACGGAACGCCGGA
GGCCGCGCGCCGCATCGAGCGCGTGCTCACCAGCGACCCCGGCATGGGCGTGTTGCGCCACGCGGACGCGGGCTACCCGG
AGGCCATCGAGGTGGCGAAAGAGCGCGGCGTGAAGATTCCCGGCATCACCACCTGA

Upstream 100 bases:

>100_bases
ACGCGACGCGGCGCGACGCGGATATCGCGGTGGCCCGGAAGCACCCCGGTTCAGGTAGTGTGCCGGGCCTTTCCGTCCGC
CACACGCTAGGAGTCCGTTC

Downstream 100 bases:

>100_bases
AGATGAAGCAGGAGGCCGCAGTGAAGCGCTTGTGCGCGGCAGGGGTCGGACTGTGGGGCGCCGCCGTCGTGGGACTGACG
GGGTGCGCCCCCACGGCGAT

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MSRVIRAPHGSTLSCKGWVQEAALRMLMNNLDPDVAERPEDLVVYGGTGKAARDWPSFDRIVSSLQNLGDDETLLVQSGK
PVGIFRTHPDAPRVLIANSNLVGRWANWEHFHELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFAAAGRFHFGTDDLA
GRLILSGGLGGMGGAQPLAATMNNAVFLGVEIDPTRARRRVETRYLDVVAKDLDEALALVKDAQEKRVGRSIAVIGNAAS
VFRELYRRGIKPDLVTDQTSAHDPLNGYIPTDLSLEAAAELRQRDPETYVRRARESMMMHVQAMNDFQKAGSHVFDYGNN
LRGQAELGGMENAFEFPGFVPAYIRPLFCEGMGPFRWVALSGDPEDIRVTDRVVRELFPQKASLQRWLNMAEERVAFQGL
PSRICWLGYGERAKAGLAFNELVRKGEVKAPIVIGRDHLDCGSVASPNRETEAMKDGTDAVADWPILNALVNAVNGASWV
SFHHGGGVGMGYSLHAGQVIVADGTPEAARRIERVLTSDPGMGVLRHADAGYPEAIEVAKERGVKIPGITT

Sequences:

>Translated_551_residues
MSRVIRAPHGSTLSCKGWVQEAALRMLMNNLDPDVAERPEDLVVYGGTGKAARDWPSFDRIVSSLQNLGDDETLLVQSGK
PVGIFRTHPDAPRVLIANSNLVGRWANWEHFHELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFAAAGRFHFGTDDLA
GRLILSGGLGGMGGAQPLAATMNNAVFLGVEIDPTRARRRVETRYLDVVAKDLDEALALVKDAQEKRVGRSIAVIGNAAS
VFRELYRRGIKPDLVTDQTSAHDPLNGYIPTDLSLEAAAELRQRDPETYVRRARESMMMHVQAMNDFQKAGSHVFDYGNN
LRGQAELGGMENAFEFPGFVPAYIRPLFCEGMGPFRWVALSGDPEDIRVTDRVVRELFPQKASLQRWLNMAEERVAFQGL
PSRICWLGYGERAKAGLAFNELVRKGEVKAPIVIGRDHLDCGSVASPNRETEAMKDGTDAVADWPILNALVNAVNGASWV
SFHHGGGVGMGYSLHAGQVIVADGTPEAARRIERVLTSDPGMGVLRHADAGYPEAIEVAKERGVKIPGITT
>Mature_550_residues
SRVIRAPHGSTLSCKGWVQEAALRMLMNNLDPDVAERPEDLVVYGGTGKAARDWPSFDRIVSSLQNLGDDETLLVQSGKP
VGIFRTHPDAPRVLIANSNLVGRWANWEHFHELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFAAAGRFHFGTDDLAG
RLILSGGLGGMGGAQPLAATMNNAVFLGVEIDPTRARRRVETRYLDVVAKDLDEALALVKDAQEKRVGRSIAVIGNAASV
FRELYRRGIKPDLVTDQTSAHDPLNGYIPTDLSLEAAAELRQRDPETYVRRARESMMMHVQAMNDFQKAGSHVFDYGNNL
RGQAELGGMENAFEFPGFVPAYIRPLFCEGMGPFRWVALSGDPEDIRVTDRVVRELFPQKASLQRWLNMAEERVAFQGLP
SRICWLGYGERAKAGLAFNELVRKGEVKAPIVIGRDHLDCGSVASPNRETEAMKDGTDAVADWPILNALVNAVNGASWVS
FHHGGGVGMGYSLHAGQVIVADGTPEAARRIERVLTSDPGMGVLRHADAGYPEAIEVAKERGVKIPGITT

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=551, Percent_Identity=34.3012704174229, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI260306182, Length=345, Percent_Identity=32.1739130434783, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71997891, Length=567, Percent_Identity=34.9206349206349, Blast_Score=342, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 60264; Mature: 60133

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVIRAPHGSTLSCKGWVQEAALRMLMNNLDPDVAERPEDLVVYGGTGKAARDWPSFDR
CCCCEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEECCCCCCCCCCCCHHH
IVSSLQNLGDDETLLVQSGKPVGIFRTHPDAPRVLIANSNLVGRWANWEHFHELEKKGLM
HHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEECCCEEECCCCHHHHHHHHHCCEE
MYGQMTAGSWIYIGTQGILQGTYETFAAAGRFHFGTDDLAGRLILSGGLGGMGGAQPLAA
EEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHCCEEEEECCCCCCCCCCHHHH
TMNNAVFLGVEIDPTRARRRVETRYLDVVAKDLDEALALVKDAQEKRVGRSIAVIGNAAS
HCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHH
VFRELYRRGIKPDLVTDQTSAHDPLNGYIPTDLSLEAAAELRQRDPETYVRRARESMMMH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VQAMNDFQKAGSHVFDYGNNLRGQAELGGMENAFEFPGFVPAYIRPLFCEGMGPFRWVAL
HHHHHHHHHCCCHHHHCCCCCCCCHHCCCCCCHHCCCCCCHHHHHHHHHCCCCCEEEEEE
SGDPEDIRVTDRVVRELFPQKASLQRWLNMAEERVAFQGLPSRICWLGYGERAKAGLAFN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCHHHH
ELVRKGEVKAPIVIGRDHLDCGSVASPNRETEAMKDGTDAVADWPILNALVNAVNGASWV
HHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEE
SFHHGGGVGMGYSLHAGQVIVADGTPEAARRIERVLTSDPGMGVLRHADAGYPEAIEVAK
EEECCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHH
ERGVKIPGITT
HCCCCCCCCCC
>Mature Secondary Structure 
SRVIRAPHGSTLSCKGWVQEAALRMLMNNLDPDVAERPEDLVVYGGTGKAARDWPSFDR
CCCEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEECCCCCCCCCCCCHHH
IVSSLQNLGDDETLLVQSGKPVGIFRTHPDAPRVLIANSNLVGRWANWEHFHELEKKGLM
HHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEECCCEEECCCCHHHHHHHHHCCEE
MYGQMTAGSWIYIGTQGILQGTYETFAAAGRFHFGTDDLAGRLILSGGLGGMGGAQPLAA
EEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHCCEEEEECCCCCCCCCCHHHH
TMNNAVFLGVEIDPTRARRRVETRYLDVVAKDLDEALALVKDAQEKRVGRSIAVIGNAAS
HCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHH
VFRELYRRGIKPDLVTDQTSAHDPLNGYIPTDLSLEAAAELRQRDPETYVRRARESMMMH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VQAMNDFQKAGSHVFDYGNNLRGQAELGGMENAFEFPGFVPAYIRPLFCEGMGPFRWVAL
HHHHHHHHHCCCHHHHCCCCCCCCHHCCCCCCHHCCCCCCHHHHHHHHHCCCCCEEEEEE
SGDPEDIRVTDRVVRELFPQKASLQRWLNMAEERVAFQGLPSRICWLGYGERAKAGLAFN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCHHHH
ELVRKGEVKAPIVIGRDHLDCGSVASPNRETEAMKDGTDAVADWPILNALVNAVNGASWV
HHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEE
SFHHGGGVGMGYSLHAGQVIVADGTPEAARRIERVLTSDPGMGVLRHADAGYPEAIEVAK
EEECCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHH
ERGVKIPGITT
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA