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The map label for this gene is yisQ [H]

Identifier: 108762689

GI number: 108762689

Start: 3245211

End: 3246623

Strand: Reverse

Name: yisQ [H]

Synonym: MXAN_2789

Alternate gene names: 108762689

Gene position: 3246623-3245211 (Counterclockwise)

Preceding gene: 108758507

Following gene: 108761502

Centisome position: 35.52

GC content: 66.95

Gene sequence:

>1413_bases
ATGGAAGTCGCAGCATCCCCGAATGCCGATCCACACGGCGCACCGTCGCTGGGGCTGTTCCGGCTCACGTGGCCCATCTT
CCTGGAGCTGCTGCTCTTCATGATGATGGGCACGGCGGACACGCTGATGCTCAGCGGCGTGTCGGATGACGCCGTCGCCT
CGGTGGGCGTCGTCAATCAGTACGTCTTCATCTGCATCCTCATCATGGAGGTCGTGGGTCACGGCGCGGCCATCGTCGTG
GCCCAGTACCTGGGCGCGCGCAGGCAGACAGAGGCCGCGCGCATCTCCGCCATCGCCGTCACCCTGAACCTCGCGCTCGG
CATCACCGTCAGCGCGGGGCTGCTGCTCAGCGGGGATGCCATCCTGGGCGGGATGAACCTTCAGGGCCACATGCTGGCGT
ACGCCAAGACGTACCTGCACATCGTCGGCGGCTTCCTGTTCATCCAGGCCCTCATCAACGTCTTCGCCGGGCTGCTGCGC
ACCTACGGCTTCACGCGCGCGTCCATGTTCGTCTCGCTGGGAATGAACGTGCTGCACGTGGGTGGCAACTACGTGCTCAT
CGCCGGCCACTTCGGCTTCCCCGCGATGGGCGTGGCGGGCGCCGCCATCTCCACCGTCGTGAGCCGGGCCATCGCGCTGG
GCGTCTTCGTCTACGTCCTGTACCGGGTGATGCCGGTGAAGATGGCGCCGCGCGACTACGTGACGTTCTCCAAGGACTAC
GTCCGCAAGATTCTCAAGGTCGGCCTGCCCTCCGCCTTCGAGCAGGCCACGTACCAGGGCTGCCAGACGGTGTTCCTGTA
CTACGTGACGTTCCTGGGCGCGGTGGCGCTGGCGTCCCGGCAGTACGCACACGCCATCTCCCAGTATGTCTTCCTGTGCA
GCCTGGCCATTGGCATGGGGACGTCCATCATCGTGGGCAGGCTGGTGGGCGCCAACCGCGCCGACGACGCGTACCAGCAG
GCCCTGCGCAGCCTGAAGTGGGGCCTGGCCATCACCCTGGTCGTGGACGTGGCCGTCGTCCTCCTCCGCGTCCCCATCGT
CTCGCTCTTCACCGAGAACGCCGACATCGTCCGGCTGACAGCGCAGGTCATCGTCATCGGGCTCGCGCTGGAGACGGGGC
GCTGCTTCAACCTGGTGCTCATCAACGCCCTGCGCGCCGCGGGTGACGCGACATTCACCGTCTACATGGGCATCGCGTCC
ATGGTCTGCATGAGCCTGCCGCTGGGCTACTACCTCGTCTTCCACATGGGCCTGGGACTGGCCGGCGTGTGGATGGCGGT
GGCCGCGGATGAATGGGTGCGCGGCATCACCATGTGGCTGCGCTGGAAGAGCCGCGCCTGGGAGAAGCAGGTCCTGGTCT
CCCTCGACGCGGAGACGGAGGCGGAGGCCGCGCCCGTCGCAGCGCACGCCTGA

Upstream 100 bases:

>100_bases
GCGCCCACACCTCGATGTCACTCGACGCGCTCTGCGCGACATGCGAGACGCTGGCGCGAGCCGAGGCATTGCCGCGCCCG
CCTCTCGGAGTCGACGCACC

Downstream 100 bases:

>100_bases
GCCGCGTGCTCAGCCGGTGACGACGATGCCGTCACGCACCGTCACCGGCCACGGCGTGAGTCGCCCGCCCGAACACGGCC
CGCCCACGCACAGCCCGTCC

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MEVAASPNADPHGAPSLGLFRLTWPIFLELLLFMMMGTADTLMLSGVSDDAVASVGVVNQYVFICILIMEVVGHGAAIVV
AQYLGARRQTEAARISAIAVTLNLALGITVSAGLLLSGDAILGGMNLQGHMLAYAKTYLHIVGGFLFIQALINVFAGLLR
TYGFTRASMFVSLGMNVLHVGGNYVLIAGHFGFPAMGVAGAAISTVVSRAIALGVFVYVLYRVMPVKMAPRDYVTFSKDY
VRKILKVGLPSAFEQATYQGCQTVFLYYVTFLGAVALASRQYAHAISQYVFLCSLAIGMGTSIIVGRLVGANRADDAYQQ
ALRSLKWGLAITLVVDVAVVLLRVPIVSLFTENADIVRLTAQVIVIGLALETGRCFNLVLINALRAAGDATFTVYMGIAS
MVCMSLPLGYYLVFHMGLGLAGVWMAVAADEWVRGITMWLRWKSRAWEKQVLVSLDAETEAEAAPVAAHA

Sequences:

>Translated_470_residues
MEVAASPNADPHGAPSLGLFRLTWPIFLELLLFMMMGTADTLMLSGVSDDAVASVGVVNQYVFICILIMEVVGHGAAIVV
AQYLGARRQTEAARISAIAVTLNLALGITVSAGLLLSGDAILGGMNLQGHMLAYAKTYLHIVGGFLFIQALINVFAGLLR
TYGFTRASMFVSLGMNVLHVGGNYVLIAGHFGFPAMGVAGAAISTVVSRAIALGVFVYVLYRVMPVKMAPRDYVTFSKDY
VRKILKVGLPSAFEQATYQGCQTVFLYYVTFLGAVALASRQYAHAISQYVFLCSLAIGMGTSIIVGRLVGANRADDAYQQ
ALRSLKWGLAITLVVDVAVVLLRVPIVSLFTENADIVRLTAQVIVIGLALETGRCFNLVLINALRAAGDATFTVYMGIAS
MVCMSLPLGYYLVFHMGLGLAGVWMAVAADEWVRGITMWLRWKSRAWEKQVLVSLDAETEAEAAPVAAHA
>Mature_470_residues
MEVAASPNADPHGAPSLGLFRLTWPIFLELLLFMMMGTADTLMLSGVSDDAVASVGVVNQYVFICILIMEVVGHGAAIVV
AQYLGARRQTEAARISAIAVTLNLALGITVSAGLLLSGDAILGGMNLQGHMLAYAKTYLHIVGGFLFIQALINVFAGLLR
TYGFTRASMFVSLGMNVLHVGGNYVLIAGHFGFPAMGVAGAAISTVVSRAIALGVFVYVLYRVMPVKMAPRDYVTFSKDY
VRKILKVGLPSAFEQATYQGCQTVFLYYVTFLGAVALASRQYAHAISQYVFLCSLAIGMGTSIIVGRLVGANRADDAYQQ
ALRSLKWGLAITLVVDVAVVLLRVPIVSLFTENADIVRLTAQVIVIGLALETGRCFNLVLINALRAAGDATFTVYMGIAS
MVCMSLPLGYYLVFHMGLGLAGVWMAVAADEWVRGITMWLRWKSRAWEKQVLVSLDAETEAEAAPVAAHA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=461, Percent_Identity=24.295010845987, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI48994890, Length=443, Percent_Identity=24.1534988713318, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50355; Mature: 50355

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVAASPNADPHGAPSLGLFRLTWPIFLELLLFMMMGTADTLMLSGVSDDAVASVGVVNQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHHH
YVFICILIMEVVGHGAAIVVAQYLGARRQTEAARISAIAVTLNLALGITVSAGLLLSGDA
HHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHEEHHHHHHHHHHCCEEEECCE
ILGGMNLQGHMLAYAKTYLHIVGGFLFIQALINVFAGLLRTYGFTRASMFVSLGMNVLHV
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEE
GGNYVLIAGHFGFPAMGVAGAAISTVVSRAIALGVFVYVLYRVMPVKMAPRDYVTFSKDY
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHH
VRKILKVGLPSAFEQATYQGCQTVFLYYVTFLGAVALASRQYAHAISQYVFLCSLAIGMG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSIIVGRLVGANRADDAYQQALRSLKWGLAITLVVDVAVVLLRVPIVSLFTENADIVRLT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AQVIVIGLALETGRCFNLVLINALRAAGDATFTVYMGIASMVCMSLPLGYYLVFHMGLGL
HHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AGVWMAVAADEWVRGITMWLRWKSRAWEKQVLVSLDAETEAEAAPVAAHA
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MEVAASPNADPHGAPSLGLFRLTWPIFLELLLFMMMGTADTLMLSGVSDDAVASVGVVNQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHHH
YVFICILIMEVVGHGAAIVVAQYLGARRQTEAARISAIAVTLNLALGITVSAGLLLSGDA
HHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHEEHHHHHHHHHHCCEEEECCE
ILGGMNLQGHMLAYAKTYLHIVGGFLFIQALINVFAGLLRTYGFTRASMFVSLGMNVLHV
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEE
GGNYVLIAGHFGFPAMGVAGAAISTVVSRAIALGVFVYVLYRVMPVKMAPRDYVTFSKDY
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHH
VRKILKVGLPSAFEQATYQGCQTVFLYYVTFLGAVALASRQYAHAISQYVFLCSLAIGMG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSIIVGRLVGANRADDAYQQALRSLKWGLAITLVVDVAVVLLRVPIVSLFTENADIVRLT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AQVIVIGLALETGRCFNLVLINALRAAGDATFTVYMGIASMVCMSLPLGYYLVFHMGLGL
HHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AGVWMAVAADEWVRGITMWLRWKSRAWEKQVLVSLDAETEAEAAPVAAHA
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]