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The map label for this gene is ligA [H]

Identifier: 108762460

GI number: 108762460

Start: 713535

End: 714608

Strand: Reverse

Name: ligA [H]

Synonym: MXAN_0615

Alternate gene names: 108762460

Gene position: 714608-713535 (Counterclockwise)

Preceding gene: 108763237

Following gene: 108759164

Centisome position: 7.82

GC content: 71.42

Gene sequence:

>1074_bases
ATGCGGCACGGAGGGTCGGTCATGGCGGACATCGCGGACGGGGAGCAGGTCTCGGTTCAGGGCTCGGGTTCCAAGCCCTA
CATCCTCAAGAACACCGGCGGTGTGTATTCGTGTTCATGCCCCGCCTGGCGCAACCAGTCGGTGGCCATCGAGCGGCGCA
CCTGCAAGCACCTGCGCCGCGTGCGCGGAGACGCCGCGGAGGACGCGCGCATCGGCGGTGACGGGTCCGGCGCTCCCGCG
GTCCCCGCGCGTCCGACGAGGAGCACGTCGGCCAGCGACGACACCAAGGCCCCACCCCTGCTGCTGGCCCAGTCGTGGGA
GAACGACGTGGACCTCACCGGCTGGTGGATGAGCGAGAAGCTGGACGGCGTGCGCGCGTACTGGGACGGGAAGCAGTTCT
GGTCGCGGCTGGGCAACGCGTTCCTCGCGCCGGAGTGGTTCACCGCGGGGCTGCCGGACTTCCCGCTCGACGGTGAGCTG
TTCGGCGGGCGCAAGCGCTTCCAGCGCACGGTGAGCATCGTCCGCCGGCAGGACCGCAGCGACGATTGGAAGGAGCTGGC
CTTCGTCGCCTTCGACGCGCCCGGCGTGGAAGGCACCTTCGAGGCGCGGCTGGAGCGCTGCCGGCAGTGGATGGAGGAGG
CGAAGCCCGCGTATGCGCAGTGGCACGCCCACGCGCGCTGTGACGGCACGCCGCACCTGCGCACGGAGCTGGCGCGCGTG
GAGTCGCTGGGTGGAGAAGGCCTCATGCTGCGCCAGCCCGGGTCGCGCTACGAGGCGGGCCGCTCCCACACGCTGCTCAA
GGTGAAGAGCTTCAAGGACGACGAAGCGCGCGTGGTGGGACACGTGGCTGGCGCGGGCCGCCACAAGGGCCGCCTGGGCG
CGCTGGAGGTGGAGCTGCGTAACGGCACGCGCTTCAGCGTGGGCACGGGCCTGTCGGACGCGGAGCGCGCATCGCCGCCA
CCCGTGGGTGCCATCATCACCTTCCGCTACCAGGAGCTGTCCAACGACGGCGTGCCACGCTTCCCGTCGTACGTGGGTGT
GCGCGTCGACGCCGCCCCCTTCGCCGCGAGCTGA

Upstream 100 bases:

>100_bases
CCAACGGCCTCGCGCCACCCCATCCGAGGCGGAATGCCCACCGCATCACGTCCTGAAACGTCGGCCCCGGGGGGTATGCT
TCATCCCATCGCCGCTCCGG

Downstream 100 bases:

>100_bases
GGCCAGCCGTCCCACGGCAGGAGTCACCGGTCCGCTGGTCGACGGAGCGGCGCCACAGTGCCACCTGACAGACGGTGCGT
GCCCGGGGTGATGCGCGCCC

Product: DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRHGGSVMADIADGEQVSVQGSGSKPYILKNTGGVYSCSCPAWRNQSVAIERRTCKHLRRVRGDAAEDARIGGDGSGAPA
VPARPTRSTSASDDTKAPPLLLAQSWENDVDLTGWWMSEKLDGVRAYWDGKQFWSRLGNAFLAPEWFTAGLPDFPLDGEL
FGGRKRFQRTVSIVRRQDRSDDWKELAFVAFDAPGVEGTFEARLERCRQWMEEAKPAYAQWHAHARCDGTPHLRTELARV
ESLGGEGLMLRQPGSRYEAGRSHTLLKVKSFKDDEARVVGHVAGAGRHKGRLGALEVELRNGTRFSVGTGLSDAERASPP
PVGAIITFRYQELSNDGVPRFPSYVGVRVDAAPFAAS

Sequences:

>Translated_357_residues
MRHGGSVMADIADGEQVSVQGSGSKPYILKNTGGVYSCSCPAWRNQSVAIERRTCKHLRRVRGDAAEDARIGGDGSGAPA
VPARPTRSTSASDDTKAPPLLLAQSWENDVDLTGWWMSEKLDGVRAYWDGKQFWSRLGNAFLAPEWFTAGLPDFPLDGEL
FGGRKRFQRTVSIVRRQDRSDDWKELAFVAFDAPGVEGTFEARLERCRQWMEEAKPAYAQWHAHARCDGTPHLRTELARV
ESLGGEGLMLRQPGSRYEAGRSHTLLKVKSFKDDEARVVGHVAGAGRHKGRLGALEVELRNGTRFSVGTGLSDAERASPP
PVGAIITFRYQELSNDGVPRFPSYVGVRVDAAPFAAS
>Mature_357_residues
MRHGGSVMADIADGEQVSVQGSGSKPYILKNTGGVYSCSCPAWRNQSVAIERRTCKHLRRVRGDAAEDARIGGDGSGAPA
VPARPTRSTSASDDTKAPPLLLAQSWENDVDLTGWWMSEKLDGVRAYWDGKQFWSRLGNAFLAPEWFTAGLPDFPLDGEL
FGGRKRFQRTVSIVRRQDRSDDWKELAFVAFDAPGVEGTFEARLERCRQWMEEAKPAYAQWHAHARCDGTPHLRTELARV
ESLGGEGLMLRQPGSRYEAGRSHTLLKVKSFKDDEARVVGHVAGAGRHKGRLGALEVELRNGTRFSVGTGLSDAERASPP
PVGAIITFRYQELSNDGVPRFPSYVGVRVDAAPFAAS

Specific function: Catalyzes efficient strand joining on a single nicked DNA [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 39155; Mature: 39155

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50966 ZF_SWIM ; PS00333 DNA_LIGASE_A2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHGGSVMADIADGEQVSVQGSGSKPYILKNTGGVYSCSCPAWRNQSVAIERRTCKHLRR
CCCCCCEEEEECCCCEEEEECCCCCCEEEECCCCEEEECCCCCCCCCEEEHHHHHHHHHH
VRGDAAEDARIGGDGSGAPAVPARPTRSTSASDDTKAPPLLLAQSWENDVDLTGWWMSEK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEHHHH
LDGVRAYWDGKQFWSRLGNAFLAPEWFTAGLPDFPLDGELFGGRKRFQRTVSIVRRQDRS
CCCHHEEECHHHHHHHHCCCEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DDWKELAFVAFDAPGVEGTFEARLERCRQWMEEAKPAYAQWHAHARCDGTPHLRTELARV
CCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHH
ESLGGEGLMLRQPGSRYEAGRSHTLLKVKSFKDDEARVVGHVAGAGRHKGRLGALEVELR
HHCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCHHEEEEHHCCCCCCCCCEEEEEEEC
NGTRFSVGTGLSDAERASPPPVGAIITFRYQELSNDGVPRFPSYVGVRVDAAPFAAS
CCCEEEECCCCCCHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MRHGGSVMADIADGEQVSVQGSGSKPYILKNTGGVYSCSCPAWRNQSVAIERRTCKHLRR
CCCCCCEEEEECCCCEEEEECCCCCCEEEECCCCEEEECCCCCCCCCEEEHHHHHHHHHH
VRGDAAEDARIGGDGSGAPAVPARPTRSTSASDDTKAPPLLLAQSWENDVDLTGWWMSEK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEHHHH
LDGVRAYWDGKQFWSRLGNAFLAPEWFTAGLPDFPLDGELFGGRKRFQRTVSIVRRQDRS
CCCHHEEECHHHHHHHHCCCEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DDWKELAFVAFDAPGVEGTFEARLERCRQWMEEAKPAYAQWHAHARCDGTPHLRTELARV
CCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHH
ESLGGEGLMLRQPGSRYEAGRSHTLLKVKSFKDDEARVVGHVAGAGRHKGRLGALEVELR
HHCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCHHEEEEHHCCCCCCCCCEEEEEEEC
NGTRFSVGTGLSDAERASPPPVGAIITFRYQELSNDGVPRFPSYVGVRVDAAPFAAS
CCCEEEECCCCCCHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550458; 7542800; 9060431 [H]