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The map label for this gene is yfhM [H]

Identifier: 108762454

GI number: 108762454

Start: 1947997

End: 1948953

Strand: Direct

Name: yfhM [H]

Synonym: MXAN_1644

Alternate gene names: 108762454

Gene position: 1947997-1948953 (Clockwise)

Preceding gene: 108763227

Following gene: 108757517

Centisome position: 21.31

GC content: 66.46

Gene sequence:

>957_bases
ATGGCTGACATCACGCATCGAACCGTAAAGACGAATGGCATCAACCTGCACCTCGCGGAGGCGGGTTCAGGGCCGCTCGT
GTTGCTCCTGCATGGTTGGCCGGAGTCCTGGTACTCGTGGCGCCATCAGCTTCCGGCGTTGGCGGCGGCGGGGTACCACG
CGGTGGCCCCAGACGTCCGTGGCTACGGCCAGAGCGACAAGCCGGAGGCCATCGAGGCGTACAGCATGAAGCAGTTGGTG
GGTGATGCGGTTGGCCTGCTGGATGCGCTGGGGGAGAGGACGGCCATCGTCATCGGCCACGACTGGGGCTCGGCGATTGC
CTGGAACTGTGCCGCCCTGCATCCCGACCGCTTCCGCGCGGTGGTGGGAATGAGCGTTCCCCATCTGGGGCGCGCGCCCA
TGCCGCCCATGCAGTTGTTTCAGCGCATGTTCGGTGAGAAGTGGTTCTACATCCTCTACTTCCAGGAGCCCGGCGTGGCC
GAGGCCGAGTTCGAGGCGGACGTCCCGAGGACGGTCCGGGCGATTCTCACGGGCACCCCCGGCTTCGATGTGACGAATCC
CGCCGTGCTGGCGAAGAAGAAGGGGGAAGGCTTCCTCGCGAGGCTCGACGTACCTGAGACGTTGCCCGGCTGGCTCACCG
AGGCGGACGTCGCGTACTTCGCGAAGGAGCTCGCCGGCAGTGGATTCCGGGGCGGGCTCAATCGCTACCGCAACATGGAC
CGGGACTGGCACGAACTGCCGGAGCTGGCGACGGCGGTCATCTCGCAGCCGGCCCTCTACATCGTCGGAGAGAAGGACCC
GGTGCGTGCCTTCTCTCCCGTTGACCCGATGAAGGCCCTGGTGCCGAACCTGGCCGACATCCACGTCATTCCCGGCGCGG
GTCATTGGGTTCAGCAGGAGCACGCCGCCGAGGTGAATGCCGCGCTGCTGGCCTTCCTGAAGAAGCTGCCGGCCTGA

Upstream 100 bases:

>100_bases
CCGTCACGCTCGTGCCGCGAAGCGGCGCGTCAAGCCTCGTGCCTGACGCGCCTGGCGCGATTGTGCGCCCCCACCGTACC
GTCACCTCTGGAGCACACCC

Downstream 100 bases:

>100_bases
GCCGCGCCCTCCATATGTTTTCGGCACGCGGACCGCGGAGTTCCACACCTGTGGCCGGTGCGGCGTCGTTCCCGTGGTGA
CCAGCCTCATCGACGGCCAG

Product: putative epoxide hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MADITHRTVKTNGINLHLAEAGSGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDVRGYGQSDKPEAIEAYSMKQLV
GDAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFRAVVGMSVPHLGRAPMPPMQLFQRMFGEKWFYILYFQEPGVA
EAEFEADVPRTVRAILTGTPGFDVTNPAVLAKKKGEGFLARLDVPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRNMD
RDWHELPELATAVISQPALYIVGEKDPVRAFSPVDPMKALVPNLADIHVIPGAGHWVQQEHAAEVNAALLAFLKKLPA

Sequences:

>Translated_318_residues
MADITHRTVKTNGINLHLAEAGSGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDVRGYGQSDKPEAIEAYSMKQLV
GDAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFRAVVGMSVPHLGRAPMPPMQLFQRMFGEKWFYILYFQEPGVA
EAEFEADVPRTVRAILTGTPGFDVTNPAVLAKKKGEGFLARLDVPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRNMD
RDWHELPELATAVISQPALYIVGEKDPVRAFSPVDPMKALVPNLADIHVIPGAGHWVQQEHAAEVNAALLAFLKKLPA
>Mature_317_residues
ADITHRTVKTNGINLHLAEAGSGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDVRGYGQSDKPEAIEAYSMKQLVG
DAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFRAVVGMSVPHLGRAPMPPMQLFQRMFGEKWFYILYFQEPGVAE
AEFEADVPRTVRAILTGTPGFDVTNPAVLAKKKGEGFLARLDVPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRNMDR
DWHELPELATAVISQPALYIVGEKDPVRAFSPVDPMKALVPNLADIHVIPGAGHWVQQEHAAEVNAALLAFLKKLPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=318, Percent_Identity=39.622641509434, Blast_Score=221, Evalue=5e-58,
Organism=Homo sapiens, GI218777840, Length=315, Percent_Identity=31.1111111111111, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI13376164, Length=315, Percent_Identity=31.1111111111111, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI218777837, Length=310, Percent_Identity=28.7096774193548, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17554012, Length=312, Percent_Identity=29.4871794871795, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17562298, Length=323, Percent_Identity=26.9349845201238, Blast_Score=114, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34734; Mature: 34603

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADITHRTVKTNGINLHLAEAGSGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDVR
CCCCCCCEEEECCCEEEEEECCCCCEEEEEECCCHHHHHHHHHCCHHHHCCCHHCCCCHH
GYGQSDKPEAIEAYSMKQLVGDAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFRA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECHHHHHH
VVGMSVPHLGRAPMPPMQLFQRMFGEKWFYILYFQEPGVAEAEFEADVPRTVRAILTGTP
HHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCC
GFDVTNPAVLAKKKGEGFLARLDVPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRNMD
CCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
RDWHELPELATAVISQPALYIVGEKDPVRAFSPVDPMKALVPNLADIHVIPGAGHWVQQE
CHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHH
HAAEVNAALLAFLKKLPA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADITHRTVKTNGINLHLAEAGSGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDVR
CCCCCCEEEECCCEEEEEECCCCCEEEEEECCCHHHHHHHHHCCHHHHCCCHHCCCCHH
GYGQSDKPEAIEAYSMKQLVGDAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFRA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECHHHHHH
VVGMSVPHLGRAPMPPMQLFQRMFGEKWFYILYFQEPGVAEAEFEADVPRTVRAILTGTP
HHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCC
GFDVTNPAVLAKKKGEGFLARLDVPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRNMD
CCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
RDWHELPELATAVISQPALYIVGEKDPVRAFSPVDPMKALVPNLADIHVIPGAGHWVQQE
CHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHH
HAAEVNAALLAFLKKLPA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]