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The map label for this gene is nprT [H]

Identifier: 108762324

GI number: 108762324

Start: 3207432

End: 3209609

Strand: Reverse

Name: nprT [H]

Synonym: MXAN_2754

Alternate gene names: 108762324

Gene position: 3209609-3207432 (Counterclockwise)

Preceding gene: 108763395

Following gene: 108759266

Centisome position: 35.12

GC content: 66.71

Gene sequence:

>2178_bases
ATGACGATTCGCCGCACCGAAGGTCCGAAGCCCACGATTCGCTCCACTGCTGCTTCCGAGGCTCAGTCGAAGACGGCCGC
GAAGCCCGCGACCATCGCCCCGAACGTCATCAAGGACGGGTTCGGCCCCGCGGCCAAGACGTCGGACCTGGCGCGCGCGG
AGAAGACGCTGAAGCCGCTGCCGCCTCCCGTGGGCCGGCTCTCCCTGGAAAGCCGCGAGGCGCAGACCGCCATCCAGACG
TCGCTGGCGCACCTGGCCCCCTCCACCCAGACCTCCATCCGCAACCCCGGCATCATCGGCGGCGTGCAGTTCCCGGCGTA
CACGCCGAAGAGCGTGGAGCGTGACTCGCTGGGCATGACGCACGTGCGTCTGGACCGCCAGCACGAGGGCGTGAAGGTCT
TCGGCGAGCAGGTCGTCACGCACCTCGACGCCGAGGGCAAGGTCAAGAGCACCACCGGCGACCAGTCTGAGATCCCGGCC
GGCCTGGGCAAGGAGAAGCCCAAGGTGTCGCACAGCCAGGCGCTGGACATCGCGATGAAGGCGTTCGACGGCAAGCCGGA
CCGCCAGCCGAACTCCGAGCGCGTCATCTACAAGGACATCTCCGGTGAGTACCACTCCGCCTACCGGGTGGAAGTCACCA
ACGTGGATGGCACCGACAATCCGCGCAAGATGAACTACCTGGTGGACGCCAACACCGGGAAGCTCTTCGAGCAGTTCAAC
ACCATTGACGGCTTCGCCCGCCAGCACGGCGCCGCGCATGGCCACACCCACGCCGAAGGCGCGGACCACGCCGACCACGC
CCACGGCGCTGCCGCGACGGCTTCCGAGATCAAGGCCTCGGCCACGCCGAAGGCGGAGATCGCCGACCTGGCCACCGTCA
CGTCGAAGATCAACGTGACCCAGGACGGCACCGTGGACCAGCTGAAGCTGGACCTGGACATCGACCACACGTTCAAGGGC
GACCTGTCGGTCACGCTCACCAGCCCCTCCGGCAAGTCGGAGACGGTGCACAACCGCAAGGGTGGCAGCGCGGACCACAT
CAAGGGCAGCTTCGACCTGAGCGGCTTCGCGGGCGAGTCCGCGAAGGGCGAGTGGACGCTGTCGGTGAAGGACAACGCGC
GCCGCGACACGGGCACGCTGAACAGCTGGGGCCTGACCATCACCCCGAAGGCCGTTGAGCCCAACGAGCCCGGTCCCGGC
GAGAAGATCGCGGACGACACGTCCATGTACAGCGGCAAGGTCGCGCTGGAAACGAAGAAGCAGGCGGACGGCACGTACAC
GCTCGAGGACGGCACGCGCGGCAAGGGCGTGGCGACCTACGACGCGATGAACCGCGAGCGCGCCAGCGGCCAGACGCAGA
TCAAGGACAACAACGACGTCTGGGGCGAGGCCACGGACCCGGAGCGCAACAAGGCCGCGGTGGACGCGCACTACGGCGGC
CAGATGATGTACGACTACATGAAGGACATCCTCGGCCGTGACTCCATCGACGGCGCGGGTGAGAAGCTGGTGTCCTACGT
CCACGTCAGCAACAACTACGTGAACGCGTACTGGGACGGCGAGAAGATGAGCTACGGCGACGGCGACGGCCGCAACTCCG
GTCCGCTCACCGCGCTGGACATCGCGGGCCATGAGATTGCCCACGGCCTCACCGAGCGCACCGCCGGCCTCATCTACCGC
GGCGAGTCCGGTGGTCTGAACGAGGCGATGAGCGACATCATGGGCGCTGGCCTCGAGTGGTACGCGTCCCAGAAGAACCC
CGACGTGAAGTTCAACTGGACGGTGGGCGAGACGGCCTGGACGCCGAAGAACGGCGACCCCACCGACGGCCTGCGCTACA
TGGACGATCCGACGAAGGACAACTACTCGGTCGACAACTACAAGAACTACCCGAAGCAGACCGAGGTGCACGGCTCCAGC
GGCATCGCGAACAACGCCTTCTACCTGCTGACCAACGGCGGAACCAACCGCACGTCCGGCATCGAAGTGAAGGACGCCAT
CGGCATGGAGAAGGGCCTGAAGATCTACTACCGCGCCCTGGCTCACTACATGACGCCGAGCACCACGTTCGCCCAGGCCC
GCACCGCGACCATCAACGCGGCGACGGACCTCTACGGCGCGGACTCCGCTGAAGTGGCGAAGGTCAAGGAGAGCTGGACC
GCCGTCGGCGTGAACTAG

Upstream 100 bases:

>100_bases
TTTCGAGAATGGCTTATTGCGTTGAAAATATCGCAAGAAACTCCGCGCCACACTGCGGCGATAACTCTTCAACCCCCTTG
CACTGAGTTCGAGACCCCCA

Downstream 100 bases:

>100_bases
TCCTCCCGCTTCACTGAAGACACCCGAGCCCGGCCCGGCCCGCGACACACCGCGGACTGGCGCCGGGCTTCGGCTTTCCA
GCGGCCGCTCAGGCCGGCGA

Product: M4 family peptidase

Products: NA

Alternate protein names: Thermostable neutral proteinase [H]

Number of amino acids: Translated: 725; Mature: 724

Protein sequence:

>725_residues
MTIRRTEGPKPTIRSTAASEAQSKTAAKPATIAPNVIKDGFGPAAKTSDLARAEKTLKPLPPPVGRLSLESREAQTAIQT
SLAHLAPSTQTSIRNPGIIGGVQFPAYTPKSVERDSLGMTHVRLDRQHEGVKVFGEQVVTHLDAEGKVKSTTGDQSEIPA
GLGKEKPKVSHSQALDIAMKAFDGKPDRQPNSERVIYKDISGEYHSAYRVEVTNVDGTDNPRKMNYLVDANTGKLFEQFN
TIDGFARQHGAAHGHTHAEGADHADHAHGAAATASEIKASATPKAEIADLATVTSKINVTQDGTVDQLKLDLDIDHTFKG
DLSVTLTSPSGKSETVHNRKGGSADHIKGSFDLSGFAGESAKGEWTLSVKDNARRDTGTLNSWGLTITPKAVEPNEPGPG
EKIADDTSMYSGKVALETKKQADGTYTLEDGTRGKGVATYDAMNRERASGQTQIKDNNDVWGEATDPERNKAAVDAHYGG
QMMYDYMKDILGRDSIDGAGEKLVSYVHVSNNYVNAYWDGEKMSYGDGDGRNSGPLTALDIAGHEIAHGLTERTAGLIYR
GESGGLNEAMSDIMGAGLEWYASQKNPDVKFNWTVGETAWTPKNGDPTDGLRYMDDPTKDNYSVDNYKNYPKQTEVHGSS
GIANNAFYLLTNGGTNRTSGIEVKDAIGMEKGLKIYYRALAHYMTPSTTFAQARTATINAATDLYGADSAEVAKVKESWT
AVGVN

Sequences:

>Translated_725_residues
MTIRRTEGPKPTIRSTAASEAQSKTAAKPATIAPNVIKDGFGPAAKTSDLARAEKTLKPLPPPVGRLSLESREAQTAIQT
SLAHLAPSTQTSIRNPGIIGGVQFPAYTPKSVERDSLGMTHVRLDRQHEGVKVFGEQVVTHLDAEGKVKSTTGDQSEIPA
GLGKEKPKVSHSQALDIAMKAFDGKPDRQPNSERVIYKDISGEYHSAYRVEVTNVDGTDNPRKMNYLVDANTGKLFEQFN
TIDGFARQHGAAHGHTHAEGADHADHAHGAAATASEIKASATPKAEIADLATVTSKINVTQDGTVDQLKLDLDIDHTFKG
DLSVTLTSPSGKSETVHNRKGGSADHIKGSFDLSGFAGESAKGEWTLSVKDNARRDTGTLNSWGLTITPKAVEPNEPGPG
EKIADDTSMYSGKVALETKKQADGTYTLEDGTRGKGVATYDAMNRERASGQTQIKDNNDVWGEATDPERNKAAVDAHYGG
QMMYDYMKDILGRDSIDGAGEKLVSYVHVSNNYVNAYWDGEKMSYGDGDGRNSGPLTALDIAGHEIAHGLTERTAGLIYR
GESGGLNEAMSDIMGAGLEWYASQKNPDVKFNWTVGETAWTPKNGDPTDGLRYMDDPTKDNYSVDNYKNYPKQTEVHGSS
GIANNAFYLLTNGGTNRTSGIEVKDAIGMEKGLKIYYRALAHYMTPSTTFAQARTATINAATDLYGADSAEVAKVKESWT
AVGVN
>Mature_724_residues
TIRRTEGPKPTIRSTAASEAQSKTAAKPATIAPNVIKDGFGPAAKTSDLARAEKTLKPLPPPVGRLSLESREAQTAIQTS
LAHLAPSTQTSIRNPGIIGGVQFPAYTPKSVERDSLGMTHVRLDRQHEGVKVFGEQVVTHLDAEGKVKSTTGDQSEIPAG
LGKEKPKVSHSQALDIAMKAFDGKPDRQPNSERVIYKDISGEYHSAYRVEVTNVDGTDNPRKMNYLVDANTGKLFEQFNT
IDGFARQHGAAHGHTHAEGADHADHAHGAAATASEIKASATPKAEIADLATVTSKINVTQDGTVDQLKLDLDIDHTFKGD
LSVTLTSPSGKSETVHNRKGGSADHIKGSFDLSGFAGESAKGEWTLSVKDNARRDTGTLNSWGLTITPKAVEPNEPGPGE
KIADDTSMYSGKVALETKKQADGTYTLEDGTRGKGVATYDAMNRERASGQTQIKDNNDVWGEATDPERNKAAVDAHYGGQ
MMYDYMKDILGRDSIDGAGEKLVSYVHVSNNYVNAYWDGEKMSYGDGDGRNSGPLTALDIAGHEIAHGLTERTAGLIYRG
ESGGLNEAMSDIMGAGLEWYASQKNPDVKFNWTVGETAWTPKNGDPTDGLRYMDDPTKDNYSVDNYKNYPKQTEVHGSSG
IANNAFYLLTNGGTNRTSGIEVKDAIGMEKGLKIYYRALAHYMTPSTTFAQARTATINAATDLYGADSAEVAKVKESWTA
VGVN

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.27 [H]

Molecular weight: Translated: 77862; Mature: 77730

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRRTEGPKPTIRSTAASEAQSKTAAKPATIAPNVIKDGFGPAAKTSDLARAEKTLKPL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCC
PPPVGRLSLESREAQTAIQTSLAHLAPSTQTSIRNPGIIGGVQFPAYTPKSVERDSLGMT
CCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHCCCCCEEECEECCCCCCCCCCCCCCCCE
HVRLDRQHEGVKVFGEQVVTHLDAEGKVKSTTGDQSEIPAGLGKEKPKVSHSQALDIAMK
EEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHH
AFDGKPDRQPNSERVIYKDISGEYHSAYRVEVTNVDGTDNPRKMNYLVDANTGKLFEQFN
HHCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHH
TIDGFARQHGAAHGHTHAEGADHADHAHGAAATASEIKASATPKAEIADLATVTSKINVT
HHHHHHHHCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHEEEEC
QDGTVDQLKLDLDIDHTFKGDLSVTLTSPSGKSETVHNRKGGSADHIKGSFDLSGFAGES
CCCCCEEEEEEEEECCEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKGEWTLSVKDNARRDTGTLNSWGLTITPKAVEPNEPGPGEKIADDTSMYSGKVALETKK
CCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHCCCEEEEEECC
QADGTYTLEDGTRGKGVATYDAMNRERASGQTQIKDNNDVWGEATDPERNKAAVDAHYGG
CCCCEEEECCCCCCCCEEEHHHHCHHHCCCCCEECCCCCCCCCCCCCCCCCEEEEECCCC
QMMYDYMKDILGRDSIDGAGEKLVSYVHVSNNYVNAYWDGEKMSYGDGDGRNSGPLTALD
HHHHHHHHHHHCCCCCCCHHHHEEEEEEECCCEEEEEECCCEECCCCCCCCCCCCEEEEE
IAGHEIAHGLTERTAGLIYRGESGGLNEAMSDIMGAGLEWYASQKNPDVKFNWTVGETAW
CCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCEE
TPKNGDPTDGLRYMDDPTKDNYSVDNYKNYPKQTEVHGSSGIANNAFYLLTNGGTNRTSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
IEVKDAIGMEKGLKIYYRALAHYMTPSTTFAQARTATINAATDLYGADSAEVAKVKESWT
EEHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECHHHCCCCCCHHHHHHHHCCE
AVGVN
EECCC
>Mature Secondary Structure 
TIRRTEGPKPTIRSTAASEAQSKTAAKPATIAPNVIKDGFGPAAKTSDLARAEKTLKPL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCC
PPPVGRLSLESREAQTAIQTSLAHLAPSTQTSIRNPGIIGGVQFPAYTPKSVERDSLGMT
CCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHCCCCCEEECEECCCCCCCCCCCCCCCCE
HVRLDRQHEGVKVFGEQVVTHLDAEGKVKSTTGDQSEIPAGLGKEKPKVSHSQALDIAMK
EEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHH
AFDGKPDRQPNSERVIYKDISGEYHSAYRVEVTNVDGTDNPRKMNYLVDANTGKLFEQFN
HHCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHH
TIDGFARQHGAAHGHTHAEGADHADHAHGAAATASEIKASATPKAEIADLATVTSKINVT
HHHHHHHHCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHEEEEC
QDGTVDQLKLDLDIDHTFKGDLSVTLTSPSGKSETVHNRKGGSADHIKGSFDLSGFAGES
CCCCCEEEEEEEEECCEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKGEWTLSVKDNARRDTGTLNSWGLTITPKAVEPNEPGPGEKIADDTSMYSGKVALETKK
CCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHCCCEEEEEECC
QADGTYTLEDGTRGKGVATYDAMNRERASGQTQIKDNNDVWGEATDPERNKAAVDAHYGG
CCCCEEEECCCCCCCCEEEHHHHCHHHCCCCCEECCCCCCCCCCCCCCCCCEEEEECCCC
QMMYDYMKDILGRDSIDGAGEKLVSYVHVSNNYVNAYWDGEKMSYGDGDGRNSGPLTALD
HHHHHHHHHHHCCCCCCCHHHHEEEEEEECCCEEEEEECCCEECCCCCCCCCCCCEEEEE
IAGHEIAHGLTERTAGLIYRGESGGLNEAMSDIMGAGLEWYASQKNPDVKFNWTVGETAW
CCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCEE
TPKNGDPTDGLRYMDDPTKDNYSVDNYKNYPKQTEVHGSSGIANNAFYLLTNGGTNRTSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
IEVKDAIGMEKGLKIYYRALAHYMTPSTTFAQARTATINAATDLYGADSAEVAKVKESWT
EEHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECHHHCCCCCCHHHHHHHHCCE
AVGVN
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2993245 [H]