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The map label for this gene is yabD [H]

Identifier: 108762295

GI number: 108762295

Start: 3275223

End: 3275999

Strand: Direct

Name: yabD [H]

Synonym: MXAN_2806

Alternate gene names: 108762295

Gene position: 3275223-3275999 (Clockwise)

Preceding gene: 108763671

Following gene: 108759289

Centisome position: 35.83

GC content: 70.79

Gene sequence:

>777_bases
ATGAAATTCGTCGACGCCCACTGTCACCTCGAGGTGAAGGACTACCCGGACGTCGTGGCCGTGCTCGACGCGGCTCGCGC
GGCGGGGCTGGTCCATGCCGTCGTGGTGGGGCAGTTCCACGGCCCGGGTAACTGGGGCAACGCGCTGGAGGTGGCGGCGG
CGCACCCGGAGTTCCTGTCGCCCACGTTGGGCATCCACCCGCACGAGGCCGCCCGGGCCACCGAGGAGGACCTGGCCACG
CTGGAGCGCACCTGCGCGCGTCCCGAGGTCCGGGCGGTGGGGGAGGCGGGCCTGGACTACTACTACGACCACTCACCGCG
TGAGGCGCAGGCGGAGGTCTTCCGGCGGCAGTGCGCGCTGGCGCTCCGGCTGGGCAAGCCGCTGGTGGTGCACGTGCGCG
ACGCGCATGACGACTGTGACGCCATCCTCGGCGAGACGGGCGTGGCGAAGGGCGTCATCCACTGCTTCACCGGTGACACG
GACGCGGCGCGGCGCTACCTGGACCGGGGCTTCCTGCTGTCGCTGTCGGGCGTCATCACCTACAAGAAGACGGAGGCGCT
CCAGGACGCGGTGCGCTTCGCGCCGTTGGACAGGCTGATGGTGGAGACGGACAGCCCGTACCTGGCGCCGGTGCCGCACC
GGGGGCGGAAGAACCAGCCCTCGCACGTGGTGGAGACGGCGAAGAAGGTCGCCGAACTCAAGGGCGTGACGCTGGAGGAG
GTGGCCTCGGTCACCACCGCCAACGCCGCCGCCCTCTTCAACCTCAACCTGCGTTGA

Upstream 100 bases:

>100_bases
TGGGCGGGGCTGAGGCGCGTGAGGCCGTTCGCAACGCGGTGAGTACCTTTCCCTCACCAGAGGCCCGCGCCGAACTGGAA
GAGCTGTTGCAGGAGGAGCC

Downstream 100 bases:

>100_bases
GGCCGCCGGCCAGGGCCGCGAGGTCCTGGTCCATCTGCGGCACGTCCAGCAGCAACGCGTCCGGGTCGTACTGGAAGTCC
GCCTGCTTCAGCTTCAGCAG

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKFVDAHCHLEVKDYPDVVAVLDAARAAGLVHAVVVGQFHGPGNWGNALEVAAAHPEFLSPTLGIHPHEAARATEEDLAT
LERTCARPEVRAVGEAGLDYYYDHSPREAQAEVFRRQCALALRLGKPLVVHVRDAHDDCDAILGETGVAKGVIHCFTGDT
DAARRYLDRGFLLSLSGVITYKKTEALQDAVRFAPLDRLMVETDSPYLAPVPHRGRKNQPSHVVETAKKVAELKGVTLEE
VASVTTANAAALFNLNLR

Sequences:

>Translated_258_residues
MKFVDAHCHLEVKDYPDVVAVLDAARAAGLVHAVVVGQFHGPGNWGNALEVAAAHPEFLSPTLGIHPHEAARATEEDLAT
LERTCARPEVRAVGEAGLDYYYDHSPREAQAEVFRRQCALALRLGKPLVVHVRDAHDDCDAILGETGVAKGVIHCFTGDT
DAARRYLDRGFLLSLSGVITYKKTEALQDAVRFAPLDRLMVETDSPYLAPVPHRGRKNQPSHVVETAKKVAELKGVTLEE
VASVTTANAAALFNLNLR
>Mature_258_residues
MKFVDAHCHLEVKDYPDVVAVLDAARAAGLVHAVVVGQFHGPGNWGNALEVAAAHPEFLSPTLGIHPHEAARATEEDLAT
LERTCARPEVRAVGEAGLDYYYDHSPREAQAEVFRRQCALALRLGKPLVVHVRDAHDDCDAILGETGVAKGVIHCFTGDT
DAARRYLDRGFLLSLSGVITYKKTEALQDAVRFAPLDRLMVETDSPYLAPVPHRGRKNQPSHVVETAKKVAELKGVTLEE
VASVTTANAAALFNLNLR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=32.4626865671642, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=32.4626865671642, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=32.2344322344322, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=31.5384615384615, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI225903424, Length=268, Percent_Identity=28.7313432835821, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=31.304347826087, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI225903439, Length=239, Percent_Identity=24.2677824267782, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI14042943, Length=239, Percent_Identity=24.2677824267782, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1787342, Length=267, Percent_Identity=43.0711610486891, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI87082439, Length=262, Percent_Identity=29.3893129770992, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI48994985, Length=205, Percent_Identity=33.1707317073171, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=267, Percent_Identity=32.5842696629214, Blast_Score=141, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=29.4339622641509, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=227, Percent_Identity=32.15859030837, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17565396, Length=303, Percent_Identity=27.0627062706271, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=32.1678321678322, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI221330018, Length=278, Percent_Identity=28.7769784172662, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24586117, Length=278, Percent_Identity=28.7769784172662, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28026; Mature: 28026

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDAHCHLEVKDYPDVVAVLDAARAAGLVHAVVVGQFHGPGNWGNALEVAAAHPEFLS
CCEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEECCCHHCC
PTLGIHPHEAARATEEDLATLERTCARPEVRAVGEAGLDYYYDHSPREAQAEVFRRQCAL
CCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ALRLGKPLVVHVRDAHDDCDAILGETGVAKGVIHCFTGDTDAARRYLDRGFLLSLSGVIT
HHHCCCCEEEEEECCCCHHHHHHCCCCHHHCEEEEECCCHHHHHHHHHCCCEEEECCEEE
YKKTEALQDAVRFAPLDRLMVETDSPYLAPVPHRGRKNQPSHVVETAKKVAELKGVTLEE
EHHHHHHHHHHHHCCHHHHEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
VASVTTANAAALFNLNLR
HHHHHCCCEEEEEEECCC
>Mature Secondary Structure
MKFVDAHCHLEVKDYPDVVAVLDAARAAGLVHAVVVGQFHGPGNWGNALEVAAAHPEFLS
CCEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEECCCHHCC
PTLGIHPHEAARATEEDLATLERTCARPEVRAVGEAGLDYYYDHSPREAQAEVFRRQCAL
CCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ALRLGKPLVVHVRDAHDDCDAILGETGVAKGVIHCFTGDTDAARRYLDRGFLLSLSGVIT
HHHCCCCEEEEEECCCCHHHHHHCCCCHHHCEEEEECCCHHHHHHHHHCCCEEEECCEEE
YKKTEALQDAVRFAPLDRLMVETDSPYLAPVPHRGRKNQPSHVVETAKKVAELKGVTLEE
EHHHHHHHHHHHHCCHHHHEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
VASVTTANAAALFNLNLR
HHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]