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The map label for this gene is glnS [H]

Identifier: 108762145

GI number: 108762145

Start: 2746958

End: 2748646

Strand: Direct

Name: glnS [H]

Synonym: MXAN_2363

Alternate gene names: 108762145

Gene position: 2746958-2748646 (Clockwise)

Preceding gene: 108759841

Following gene: 108763004

Centisome position: 30.06

GC content: 65.54

Gene sequence:

>1689_bases
ATGACGACGACGAACGAAACGCAGGGCCTGAACTTCCTCCAGGAAATCATCGAGGAAGACCAGCGGACGGGAAAGTACGC
GGGCCGCGTGCACACCCGCTTCCCGCCCGAGCCCAACGGCTACCTCCACATCGGCCACGCCAAGTCCATCTGCCTCAACT
TCGGGCTGGCGCAGCAATACGGAGGCAAGTGCAACCTGCGCTTCGACGACACCAACCCCGTCACCGAGGACACCGACTAC
GTCGAGGCCATCCAGCGTGACGTGAAGTGGCTGGGCTTCGAGTGGGAGGACCGGAAGTTCTTCGCGTCCGACTACTTCCC
GAAGCTCTACGACTTCGCCGTGCAGCTCATCAAGCAGGGCAAGGCGTACGTGTGCAGCCTGTCCCCTGAGGAGATTCGCG
AGTACCGCGGCGACTTCACCACGCCGGGGCGCAACAGTCCGTACCGCGAGCGCTCCGTGGAGGAGAACCTGGACCTGTTC
CACCGCATGCGCGCGGGCGAGTTCTCCGACGGCCAGCACACCCTGCGGGCGAAGATCGACATGGCGTCGCCCAACCCCGT
GCTGCGCGACCCGCCCATCTACCGCATCCGTCACGCGCACCATCACCGCACCGGCGACGCGTGGCCCATCTACCCGCTCT
ACGACTTCGCGCACTGCCTGTCGGACGCGATTGAGGGCATCACCCACTCCATCTGCACGCTGGAGTTCGAGAACCGGCGC
GTGCTGTACGACTGGATTGTCGACAACCTCGTCAGCGGGGACCGGCCGTACCAGTACGAGTTCAACCGGCTAAACCTCAA
CTACACGGTGATGAGCAAGCGCAAGCTGCTCAAGCTGGTGACGGAGGGCTTCGTGGCCGGGTGGGATGACCCCCGGATGA
TGACGATTACCGGCCTGCGCCGCCGTGGCTTCACGCCGGCGTCCATCCGGGACTTCGCCACGCGCGTGGGCGTGGGCAAG
GCGCAGCAGCTCATCGACATGAGCCTGTTGGAGCTGTGCATCCGCGAGGACCTCAACGAGACGGCTCCGCGCGCCATGGC
GGTGATGCGCCCGTTGAAGGTGGTCCTGGAGAACTACCCGGAGGGGCAGACGGAGCTGCTGGAGGTGCAGAACCATCCGC
AGAAGCCGGAGATGGGGACGCGCCAGGTGCCTTTCATGCGCGAGCTGTACATCGAGGCGGACGACTTCATGGAGGACCCG
CCGAAGGGGTTCTTCCGGTTGGCGCCCGGCAAGGAGGTGCGGCTGCGCTCGGCGTACTTCATCAAGTGCGAGCAGGTCAT
CAAGGACGCCGCGGGTAACGTGGTGGAGTTGCGTTGCTCGTATGACCCGGCCACGCGCGGCGGCAACGCGCCGGATGGCC
GCAAGGTGAAGGGCACGCTGCACTGGGTACCCGGCAACGCGCCCGTCGCGGAGGTCCGCCTCTATGACCGGCTCTTCTCC
GTGGAGGCGCCGGACGCGGACGACTCCAAGGACTTCACCACGTTCCTCAACCCGACCAGCCTCCAGACGCTGCGCGACGC
CCGCGTCGAGCCGATGCTGGTGGATGCCGCCGTGGAGTCGCGCTACCAGTTCGAGCGCACCGGGTACTTCTACGTGGACC
CGAAGGACTCGAAGCCGGGCAAGCCCGTCTTCAACCGTACGGTGACGCTGAAGGACTCATGGACGAAGGAGCAGGCCAAG
GGGAAGTAG

Upstream 100 bases:

>100_bases
CTTCGGGACGTCCATCTTCGTCCCGGAGGCCCGGCCGGCGGCATCTGGAGCAGGAATCCCTTGCCGGCCCCCGGCTGCTT
CACGAGGATTCGCCCCCATC

Downstream 100 bases:

>100_bases
TCCCTGGCGTGCTTCCGGGTGCCGCCCACGCTGGCGGCACCCGGCACGGTGCTTTCGTCGGAAGGCTCGCGGCCTACCGC
GTCGCGGCGGGCTGCTCGAG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MTTTNETQGLNFLQEIIEEDQRTGKYAGRVHTRFPPEPNGYLHIGHAKSICLNFGLAQQYGGKCNLRFDDTNPVTEDTDY
VEAIQRDVKWLGFEWEDRKFFASDYFPKLYDFAVQLIKQGKAYVCSLSPEEIREYRGDFTTPGRNSPYRERSVEENLDLF
HRMRAGEFSDGQHTLRAKIDMASPNPVLRDPPIYRIRHAHHHRTGDAWPIYPLYDFAHCLSDAIEGITHSICTLEFENRR
VLYDWIVDNLVSGDRPYQYEFNRLNLNYTVMSKRKLLKLVTEGFVAGWDDPRMMTITGLRRRGFTPASIRDFATRVGVGK
AQQLIDMSLLELCIREDLNETAPRAMAVMRPLKVVLENYPEGQTELLEVQNHPQKPEMGTRQVPFMRELYIEADDFMEDP
PKGFFRLAPGKEVRLRSAYFIKCEQVIKDAAGNVVELRCSYDPATRGGNAPDGRKVKGTLHWVPGNAPVAEVRLYDRLFS
VEAPDADDSKDFTTFLNPTSLQTLRDARVEPMLVDAAVESRYQFERTGYFYVDPKDSKPGKPVFNRTVTLKDSWTKEQAK
GK

Sequences:

>Translated_562_residues
MTTTNETQGLNFLQEIIEEDQRTGKYAGRVHTRFPPEPNGYLHIGHAKSICLNFGLAQQYGGKCNLRFDDTNPVTEDTDY
VEAIQRDVKWLGFEWEDRKFFASDYFPKLYDFAVQLIKQGKAYVCSLSPEEIREYRGDFTTPGRNSPYRERSVEENLDLF
HRMRAGEFSDGQHTLRAKIDMASPNPVLRDPPIYRIRHAHHHRTGDAWPIYPLYDFAHCLSDAIEGITHSICTLEFENRR
VLYDWIVDNLVSGDRPYQYEFNRLNLNYTVMSKRKLLKLVTEGFVAGWDDPRMMTITGLRRRGFTPASIRDFATRVGVGK
AQQLIDMSLLELCIREDLNETAPRAMAVMRPLKVVLENYPEGQTELLEVQNHPQKPEMGTRQVPFMRELYIEADDFMEDP
PKGFFRLAPGKEVRLRSAYFIKCEQVIKDAAGNVVELRCSYDPATRGGNAPDGRKVKGTLHWVPGNAPVAEVRLYDRLFS
VEAPDADDSKDFTTFLNPTSLQTLRDARVEPMLVDAAVESRYQFERTGYFYVDPKDSKPGKPVFNRTVTLKDSWTKEQAK
GK
>Mature_561_residues
TTTNETQGLNFLQEIIEEDQRTGKYAGRVHTRFPPEPNGYLHIGHAKSICLNFGLAQQYGGKCNLRFDDTNPVTEDTDYV
EAIQRDVKWLGFEWEDRKFFASDYFPKLYDFAVQLIKQGKAYVCSLSPEEIREYRGDFTTPGRNSPYRERSVEENLDLFH
RMRAGEFSDGQHTLRAKIDMASPNPVLRDPPIYRIRHAHHHRTGDAWPIYPLYDFAHCLSDAIEGITHSICTLEFENRRV
LYDWIVDNLVSGDRPYQYEFNRLNLNYTVMSKRKLLKLVTEGFVAGWDDPRMMTITGLRRRGFTPASIRDFATRVGVGKA
QQLIDMSLLELCIREDLNETAPRAMAVMRPLKVVLENYPEGQTELLEVQNHPQKPEMGTRQVPFMRELYIEADDFMEDPP
KGFFRLAPGKEVRLRSAYFIKCEQVIKDAAGNVVELRCSYDPATRGGNAPDGRKVKGTLHWVPGNAPVAEVRLYDRLFSV
EAPDADDSKDFTTFLNPTSLQTLRDARVEPMLVDAAVESRYQFERTGYFYVDPKDSKPGKPVFNRTVTLKDSWTKEQAKG
K

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=546, Percent_Identity=47.2527472527472, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI62241042, Length=542, Percent_Identity=33.5793357933579, Blast_Score=273, Evalue=3e-73,
Organism=Escherichia coli, GI1786895, Length=552, Percent_Identity=60.1449275362319, Blast_Score=686, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=123, Percent_Identity=30.0813008130081, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=535, Percent_Identity=43.3644859813084, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17511007, Length=374, Percent_Identity=36.8983957219251, Blast_Score=233, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6324742, Length=568, Percent_Identity=41.9014084507042, Blast_Score=415, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321192, Length=522, Percent_Identity=37.1647509578544, Blast_Score=305, Evalue=8e-84,
Organism=Drosophila melanogaster, GI17864488, Length=545, Percent_Identity=44.2201834862385, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24649466, Length=520, Percent_Identity=33.8461538461538, Blast_Score=259, Evalue=4e-69,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64689; Mature: 64558

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTNETQGLNFLQEIIEEDQRTGKYAGRVHTRFPPEPNGYLHIGHAKSICLNFGLAQQY
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEECCHHHHHHHCCHHHHC
GGKCNLRFDDTNPVTEDTDYVEAIQRDVKWLGFEWEDRKFFASDYFPKLYDFAVQLIKQG
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHCCHHHHHHHHHHHHCC
KAYVCSLSPEEIREYRGDFTTPGRNSPYRERSVEENLDLFHRMRAGEFSDGQHTLRAKID
CCEEEECCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
MASPNPVLRDPPIYRIRHAHHHRTGDAWPIYPLYDFAHCLSDAIEGITHSICTLEFENRR
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCE
VLYDWIVDNLVSGDRPYQYEFNRLNLNYTVMSKRKLLKLVTEGFVAGWDDPRMMTITGLR
EEHHHHHHHHHCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECHH
RRGFTPASIRDFATRVGVGKAQQLIDMSLLELCIREDLNETAPRAMAVMRPLKVVLENYP
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGQTELLEVQNHPQKPEMGTRQVPFMRELYIEADDFMEDPPKGFFRLAPGKEVRLRSAYF
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCCEEEECCCCCEEECHHHH
IKCEQVIKDAAGNVVELRCSYDPATRGGNAPDGRKVKGTLHWVPGNAPVAEVRLYDRLFS
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHC
VEAPDADDSKDFTTFLNPTSLQTLRDARVEPMLVDAAVESRYQFERTGYFYVDPKDSKPG
CCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCEEEECCCCCCCC
KPVFNRTVTLKDSWTKEQAKGK
CCHHCEEEEECCCCCCHHCCCC
>Mature Secondary Structure 
TTTNETQGLNFLQEIIEEDQRTGKYAGRVHTRFPPEPNGYLHIGHAKSICLNFGLAQQY
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEECCHHHHHHHCCHHHHC
GGKCNLRFDDTNPVTEDTDYVEAIQRDVKWLGFEWEDRKFFASDYFPKLYDFAVQLIKQG
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHCCHHHHHHHHHHHHCC
KAYVCSLSPEEIREYRGDFTTPGRNSPYRERSVEENLDLFHRMRAGEFSDGQHTLRAKID
CCEEEECCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
MASPNPVLRDPPIYRIRHAHHHRTGDAWPIYPLYDFAHCLSDAIEGITHSICTLEFENRR
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCE
VLYDWIVDNLVSGDRPYQYEFNRLNLNYTVMSKRKLLKLVTEGFVAGWDDPRMMTITGLR
EEHHHHHHHHHCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECHH
RRGFTPASIRDFATRVGVGKAQQLIDMSLLELCIREDLNETAPRAMAVMRPLKVVLENYP
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGQTELLEVQNHPQKPEMGTRQVPFMRELYIEADDFMEDPPKGFFRLAPGKEVRLRSAYF
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCCEEEECCCCCEEECHHHH
IKCEQVIKDAAGNVVELRCSYDPATRGGNAPDGRKVKGTLHWVPGNAPVAEVRLYDRLFS
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHC
VEAPDADDSKDFTTFLNPTSLQTLRDARVEPMLVDAAVESRYQFERTGYFYVDPKDSKPG
CCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCEEEECCCCCCCC
KPVFNRTVTLKDSWTKEQAKGK
CCHHCEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]