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The map label for this gene is aspS [H]

Identifier: 108761988

GI number: 108761988

Start: 5870358

End: 5872178

Strand: Reverse

Name: aspS [H]

Synonym: MXAN_4684

Alternate gene names: 108761988

Gene position: 5872178-5870358 (Counterclockwise)

Preceding gene: 108761402

Following gene: 108759878

Centisome position: 64.25

GC content: 67.22

Gene sequence:

>1821_bases
ATGGCAGTCCCGTTCATCTCCGAGGTCAAGCGTACCCACACTTGCGGTCAGCTCACCGCGACCAACGTCGGCGAGGAAGT
CGTCCTCTTCGGCTGGGTGCACAACCGCCGAGACCACGGCGGCGCGGTGTTCATCGACCTGCGAGATCGGGATGGCCTCA
CGCAGGTGGTGTTCGAGCCGGACCACGCGGAGGCGCACGCGCTCGCCGGCAGCCTCCGGCTGGAGTACTGCGTGGGCGTG
CGCGGCAAGGTCGTCTCGCGCGGGAAGAACGTGAACCCGAAGATGAAGACGGGTGAAATCGAGGTCCGGGCCAGCGACCT
CACCATCTTCAACCGTTCGGAGCCGACGCCGTTCCCCGTCGAGGACAGCATCGACACGTCCGAGGAGAAGCGCCTGGCCC
ACCGCTTCCTGGACCTGCGCCGCGCGCCGCTCCAGCACTCGCTGATGACGCGCTCGAAGATGAACGCGCTGACGCGCTCG
TACATGGTGGGCAACGGGTTCCTGGAGCTGGAGACGCCCTTCATGGGCAAGTACACGCCGGGCGGCGCGCGCAACTTCCT
GGTCCCCAGCCGTCTCAACGCGGGCAAGTTCTACGCGCTGGCGGAGAGCCCGCAGCTCTACAAGCAGTTGTTCATGGTGG
CGGGCTTCGACCGGTACTTCCAGATCGTCAAGTGCTTCCGCGACGAGGACCTGCGCGTGGACCGGCAGCCGGAGTTCACG
CAGATCGACGTGGAGATGAGCTTCGTCACCCAGGACGACATCTTCACGATGATTGAGGGCCTGCTGAAGAAGCTGTGGGG
CGAGGTGCTGGGCATCGACATCCCCACGCCCTTCATGCGGATGGACTTCTACGAGTCCATGGCGAAGTACGGCAACGACA
AGCCGGACCTGCGCTTCGGGCTGGAGCACGTGGTGCTCACCGACCTCATTCGTGAGCACGGCGAGGGCGGCGGCGTCCCG
ATGATTTGGGAGGCGGTGCAGAACAAGGGCATCGTCAAGGCCATGGTCGTCCCCGCGGAGAAGGCGATGAGCCGCGCGGA
GAGCGACAAGCTGGAGGAGTTCGCCAAGCAGGCGGGCGCCAAGGGCCTGGCCCGCGCGAAGGTGGCGGACGGGGGTGAGT
GGACGCAGTCCCCGCTGTCCAAGACGATCAGCCCCGCGCTGCGGCAGGCCATCAACCAGGCCGTGGGCGCGAAGACGGGC
GACCTCCTCCTGTTCCAGTTCGGCAAGGAGGCGCTGGTCCACACGGTGATGGCCAACCTGCGCGTGCACGTGGCCAAGAA
GCTGGGCCTGATTCCGGAGTACGGCAGCGGCGGCCAGTGGAAGTTCCTGTGGGTCGTGAACCCGCCGCTGTTCGAGTACG
ACGACGAGACGAACACCTGGGCGGCGGCGCACCACGCCTTCACGCGTCCGCACGACGAGGACGTGGCCTACCTGCTCACG
GACCCGGGCCGGGTGAAGTGCCACCGCTACGACGTGGTGCTCAACGGCTTCGAGATTGGCGGCGGCTCCATCCGTCTCCA
TGACCCGAAGGTGCAGGCGGAGGTGTTCAAGGCGCTGGGCATCAGCGACGAGGACGCGCGCGCCAAGTTCGGCTTCCTGC
TGGACGCGCTGAAGTTCGGCGCTCCGCCGCATGGCGGCATCGCGCTGGGCATGGACCGGCTGGCCATGCTGCTCACGGGC
GCCGAGTCCCTGCGCGACGTGATTCCGTTCCCGAAGTCGAAGACGGGCACCGACCTGATGACGGGCGCCCCCGGCGACGT
GGACGACCGGCAGCTGCGTGAGATCCACGTGCGGCCGGTGCCCGTGGCGCCCAAGGCCTAG

Upstream 100 bases:

>100_bases
GTTTGAGACGTACCCGGGGCGCTCGGACTCCTTGACGCGTCGTTTCCGCGATCCGTATGGTGCTTCGCCTTTTCCCCCTT
CGAATCCAGCAGGCGGTGCC

Downstream 100 bases:

>100_bases
TTCGTCAGACGCGAGCCCTCGCTCGCGCGGTCCCGCCACCCCTTTTGACGCGGGGTGGCGGCAGGCCCGCCGTGCCCTGA
ACATGGCCACGGAGTGGAGT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MAVPFISEVKRTHTCGQLTATNVGEEVVLFGWVHNRRDHGGAVFIDLRDRDGLTQVVFEPDHAEAHALAGSLRLEYCVGV
RGKVVSRGKNVNPKMKTGEIEVRASDLTIFNRSEPTPFPVEDSIDTSEEKRLAHRFLDLRRAPLQHSLMTRSKMNALTRS
YMVGNGFLELETPFMGKYTPGGARNFLVPSRLNAGKFYALAESPQLYKQLFMVAGFDRYFQIVKCFRDEDLRVDRQPEFT
QIDVEMSFVTQDDIFTMIEGLLKKLWGEVLGIDIPTPFMRMDFYESMAKYGNDKPDLRFGLEHVVLTDLIREHGEGGGVP
MIWEAVQNKGIVKAMVVPAEKAMSRAESDKLEEFAKQAGAKGLARAKVADGGEWTQSPLSKTISPALRQAINQAVGAKTG
DLLLFQFGKEALVHTVMANLRVHVAKKLGLIPEYGSGGQWKFLWVVNPPLFEYDDETNTWAAAHHAFTRPHDEDVAYLLT
DPGRVKCHRYDVVLNGFEIGGGSIRLHDPKVQAEVFKALGISDEDARAKFGFLLDALKFGAPPHGGIALGMDRLAMLLTG
AESLRDVIPFPKSKTGTDLMTGAPGDVDDRQLREIHVRPVPVAPKA

Sequences:

>Translated_606_residues
MAVPFISEVKRTHTCGQLTATNVGEEVVLFGWVHNRRDHGGAVFIDLRDRDGLTQVVFEPDHAEAHALAGSLRLEYCVGV
RGKVVSRGKNVNPKMKTGEIEVRASDLTIFNRSEPTPFPVEDSIDTSEEKRLAHRFLDLRRAPLQHSLMTRSKMNALTRS
YMVGNGFLELETPFMGKYTPGGARNFLVPSRLNAGKFYALAESPQLYKQLFMVAGFDRYFQIVKCFRDEDLRVDRQPEFT
QIDVEMSFVTQDDIFTMIEGLLKKLWGEVLGIDIPTPFMRMDFYESMAKYGNDKPDLRFGLEHVVLTDLIREHGEGGGVP
MIWEAVQNKGIVKAMVVPAEKAMSRAESDKLEEFAKQAGAKGLARAKVADGGEWTQSPLSKTISPALRQAINQAVGAKTG
DLLLFQFGKEALVHTVMANLRVHVAKKLGLIPEYGSGGQWKFLWVVNPPLFEYDDETNTWAAAHHAFTRPHDEDVAYLLT
DPGRVKCHRYDVVLNGFEIGGGSIRLHDPKVQAEVFKALGISDEDARAKFGFLLDALKFGAPPHGGIALGMDRLAMLLTG
AESLRDVIPFPKSKTGTDLMTGAPGDVDDRQLREIHVRPVPVAPKA
>Mature_605_residues
AVPFISEVKRTHTCGQLTATNVGEEVVLFGWVHNRRDHGGAVFIDLRDRDGLTQVVFEPDHAEAHALAGSLRLEYCVGVR
GKVVSRGKNVNPKMKTGEIEVRASDLTIFNRSEPTPFPVEDSIDTSEEKRLAHRFLDLRRAPLQHSLMTRSKMNALTRSY
MVGNGFLELETPFMGKYTPGGARNFLVPSRLNAGKFYALAESPQLYKQLFMVAGFDRYFQIVKCFRDEDLRVDRQPEFTQ
IDVEMSFVTQDDIFTMIEGLLKKLWGEVLGIDIPTPFMRMDFYESMAKYGNDKPDLRFGLEHVVLTDLIREHGEGGGVPM
IWEAVQNKGIVKAMVVPAEKAMSRAESDKLEEFAKQAGAKGLARAKVADGGEWTQSPLSKTISPALRQAINQAVGAKTGD
LLLFQFGKEALVHTVMANLRVHVAKKLGLIPEYGSGGQWKFLWVVNPPLFEYDDETNTWAAAHHAFTRPHDEDVAYLLTD
PGRVKCHRYDVVLNGFEIGGGSIRLHDPKVQAEVFKALGISDEDARAKFGFLLDALKFGAPPHGGIALGMDRLAMLLTGA
ESLRDVIPFPKSKTGTDLMTGAPGDVDDRQLREIHVRPVPVAPKA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=604, Percent_Identity=40.5629139072848, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI45439306, Length=327, Percent_Identity=27.217125382263, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI5031815, Length=290, Percent_Identity=26.8965517241379, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI194272210, Length=290, Percent_Identity=26.8965517241379, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1788173, Length=599, Percent_Identity=47.4123539232053, Blast_Score=530, Evalue=1e-151,
Organism=Escherichia coli, GI1790571, Length=314, Percent_Identity=28.9808917197452, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789256, Length=314, Percent_Identity=28.343949044586, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32566633, Length=607, Percent_Identity=34.2668863261944, Blast_Score=314, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI71994340, Length=305, Percent_Identity=25.5737704918033, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17535927, Length=305, Percent_Identity=25.5737704918033, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=305, Percent_Identity=25.5737704918033, Blast_Score=87, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6325153, Length=314, Percent_Identity=35.9872611464968, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323011, Length=253, Percent_Identity=31.6205533596838, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320242, Length=260, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584738, Length=601, Percent_Identity=37.7703826955075, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17136276, Length=237, Percent_Identity=26.1603375527426, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640849, Length=319, Percent_Identity=25.0783699059561, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640851, Length=319, Percent_Identity=25.0783699059561, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67344; Mature: 67213

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPFISEVKRTHTCGQLTATNVGEEVVLFGWVHNRRDHGGAVFIDLRDRDGLTQVVFEP
CCCCCHHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEECC
DHAEAHALAGSLRLEYCVGVRGKVVSRGKNVNPKMKTGEIEVRASDLTIFNRSEPTPFPV
CCCHHHHHHHHCEEEEEECCCCHHHHCCCCCCCCEECCEEEEEEEEEEEEECCCCCCCCC
EDSIDTSEEKRLAHRFLDLRRAPLQHSLMTRSKMNALTRSYMVGNGFLELETPFMGKYTP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCC
GGARNFLVPSRLNAGKFYALAESPQLYKQLFMVAGFDRYFQIVKCFRDEDLRVDRQPEFT
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCE
QIDVEMSFVTQDDIFTMIEGLLKKLWGEVLGIDIPTPFMRMDFYESMAKYGNDKPDLRFG
EEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
LEHVVLTDLIREHGEGGGVPMIWEAVQNKGIVKAMVVPAEKAMSRAESDKLEEFAKQAGA
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCC
KGLARAKVADGGEWTQSPLSKTISPALRQAINQAVGAKTGDLLLFQFGKEALVHTVMANL
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCHHHHHHHHHHHH
RVHVAKKLGLIPEYGSGGQWKFLWVVNPPLFEYDDETNTWAAAHHAFTRPHDEDVAYLLT
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEE
DPGRVKCHRYDVVLNGFEIGGGSIRLHDPKVQAEVFKALGISDEDARAKFGFLLDALKFG
CCCCEEEEEEEEEEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
APPHGGIALGMDRLAMLLTGAESLRDVIPFPKSKTGTDLMTGAPGDVDDRQLREIHVRPV
CCCCCCEEHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHEECCCC
PVAPKA
CCCCCC
>Mature Secondary Structure 
AVPFISEVKRTHTCGQLTATNVGEEVVLFGWVHNRRDHGGAVFIDLRDRDGLTQVVFEP
CCCCHHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEECC
DHAEAHALAGSLRLEYCVGVRGKVVSRGKNVNPKMKTGEIEVRASDLTIFNRSEPTPFPV
CCCHHHHHHHHCEEEEEECCCCHHHHCCCCCCCCEECCEEEEEEEEEEEEECCCCCCCCC
EDSIDTSEEKRLAHRFLDLRRAPLQHSLMTRSKMNALTRSYMVGNGFLELETPFMGKYTP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCC
GGARNFLVPSRLNAGKFYALAESPQLYKQLFMVAGFDRYFQIVKCFRDEDLRVDRQPEFT
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCE
QIDVEMSFVTQDDIFTMIEGLLKKLWGEVLGIDIPTPFMRMDFYESMAKYGNDKPDLRFG
EEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
LEHVVLTDLIREHGEGGGVPMIWEAVQNKGIVKAMVVPAEKAMSRAESDKLEEFAKQAGA
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCC
KGLARAKVADGGEWTQSPLSKTISPALRQAINQAVGAKTGDLLLFQFGKEALVHTVMANL
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCHHHHHHHHHHHH
RVHVAKKLGLIPEYGSGGQWKFLWVVNPPLFEYDDETNTWAAAHHAFTRPHDEDVAYLLT
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEE
DPGRVKCHRYDVVLNGFEIGGGSIRLHDPKVQAEVFKALGISDEDARAKFGFLLDALKFG
CCCCEEEEEEEEEEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
APPHGGIALGMDRLAMLLTGAESLRDVIPFPKSKTGTDLMTGAPGDVDDRQLREIHVRPV
CCCCCCEEHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHEECCCC
PVAPKA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA