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The map label for this gene is masK [H]

Identifier: 108761985

GI number: 108761985

Start: 2518119

End: 2519336

Strand: Direct

Name: masK [H]

Synonym: MXAN_2177

Alternate gene names: 108761985

Gene position: 2518119-2519336 (Clockwise)

Preceding gene: 108763095

Following gene: 108757872

Centisome position: 27.55

GC content: 65.76

Gene sequence:

>1218_bases
GTGAGGGCGTTCCCTCAACCGGATGCCGCAGGTAGCGTTTTCCTCGTCGCGTTGGTTGCGAGTTCGCACACGAGGGGCAA
CGGCATGTCGAAGGCAATCGAGTTCAAGATCCCACGGGGGGCGATCCTCTTCTCGGCGGGCGGGGTCGGCTACGAGTACC
GCGAGGACTTAGGGCCGACTCACCACGGGATGGCCCTGTTCGTAGCTCGGCTGCGAACCGCGTCCGGGGCACCGCGCGGG
AAGGTGCTGCTCAAGGCGGTTCCGGCTCCATCGGAAACGGAAGGGGCTCGGGTCATGCGTGCTCGGGCGAAGCTCGATGA
GCAGGTTCGCCTTGCTACCTTCCTCAATCACCCGTCCATCCTCAAGGTGCATGGGCTGCACAAGGTCGAGGGCTATTGGT
ACGTCAGTACGGAGCACCCGGATGGTCACTCCCTGAATGAGCTGCTGACGCTCGTTGGTGAGAGTCAGCGATGGTTCCCG
CCGCTCTTCGTTCTCTACGTCGGCGCTCAGGTCGCAGCGGCCCTTGAGCACGCGCACGCCGCGAAGGACGAGCAGGGACG
GCCACTCAACATCGTTCATCGGGCCGTCGACGTTGAGCACGTCTTCGTCAACTGGGACGGGACGGTTCAGCTCGCCGACT
TCGGCCTCGCGCTGTCTGACTTGCCGGGCCGAGTGGCCTCTTCGGCGCGGGGCCCTTACGGGGACCACTTCTACTCGTCA
CCGGAGATGCTTCTAGGGGGGAGCGTCGATGCGCGCTCCGACCTCTTCATGCTGGGCGTCGTGCTGCTCGAACTGGCAAC
GGGGAAGAACCTGCTCTTTTGCCCGGACGACATCACGCCCGAAGTCATGGGCTCGTTGCCCACGAAGAAGCGTCGTCGGG
TCGCTCGGGCAATCAAGCGGGCCACGCTCGCAGGGGCGCCGCCGTTGGTGGCCGACGCGATTTGGCGCGCGGCGACACTG
ACGGCTGCGGACGTAGACGCGATGACTGAGGGGCTTCCCCAGGGGCTGCGCGTGACGCTGAATCGGCTACTTCGGGTTGC
CCCTCGTGAGCGCTACCAGTCAGCGGGGGAAAGTCATGGGCTCGTTGCCCACGAAGAAGCGTCGTCGGGTCGCTCGGGCA
ATCAAGCGGGCCACGCTCGCAGGGGCGCCGCCGTTGGTGGCCGACGCGATTTGGCGCGCGGCGACACTGACGGCTGCGGA
CGTAGACGCGATGACTGA

Upstream 100 bases:

>100_bases
GGGGCGGCTACGTCGTGGACCGCTGGCCCTGACCGCAGGGGGGACGTAATAGGTAGGAGGTCAAATTCGGGCCGAATACG
CCGTTTTGACCCCATGACCC

Downstream 100 bases:

>100_bases
GGGGCTTCCCCAGGGGCTGCGCGTGACGCTGAATCGGCTACTTCGGGTTGCCCCTCGTGAGCGCTACCAGTCAGCGGGGG
AGTTGGCTGCCGACCTGGCG

Product: putative serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRAFPQPDAAGSVFLVALVASSHTRGNGMSKAIEFKIPRGAILFSAGGVGYEYREDLGPTHHGMALFVARLRTASGAPRG
KVLLKAVPAPSETEGARVMRARAKLDEQVRLATFLNHPSILKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFP
PLFVLYVGAQVAAALEHAHAAKDEQGRPLNIVHRAVDVEHVFVNWDGTVQLADFGLALSDLPGRVASSARGPYGDHFYSS
PEMLLGGSVDARSDLFMLGVVLLELATGKNLLFCPDDITPEVMGSLPTKKRRRVARAIKRATLAGAPPLVADAIWRAATL
TAADVDAMTEGLPQGLRVTLNRLLRVAPRERYQSAGESHGLVAHEEASSGRSGNQAGHARRGAAVGGRRDLARGDTDGCG
RRRDD

Sequences:

>Translated_405_residues
MRAFPQPDAAGSVFLVALVASSHTRGNGMSKAIEFKIPRGAILFSAGGVGYEYREDLGPTHHGMALFVARLRTASGAPRG
KVLLKAVPAPSETEGARVMRARAKLDEQVRLATFLNHPSILKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFP
PLFVLYVGAQVAAALEHAHAAKDEQGRPLNIVHRAVDVEHVFVNWDGTVQLADFGLALSDLPGRVASSARGPYGDHFYSS
PEMLLGGSVDARSDLFMLGVVLLELATGKNLLFCPDDITPEVMGSLPTKKRRRVARAIKRATLAGAPPLVADAIWRAATL
TAADVDAMTEGLPQGLRVTLNRLLRVAPRERYQSAGESHGLVAHEEASSGRSGNQAGHARRGAAVGGRRDLARGDTDGCG
RRRDD
>Mature_405_residues
MRAFPQPDAAGSVFLVALVASSHTRGNGMSKAIEFKIPRGAILFSAGGVGYEYREDLGPTHHGMALFVARLRTASGAPRG
KVLLKAVPAPSETEGARVMRARAKLDEQVRLATFLNHPSILKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFP
PLFVLYVGAQVAAALEHAHAAKDEQGRPLNIVHRAVDVEHVFVNWDGTVQLADFGLALSDLPGRVASSARGPYGDHFYSS
PEMLLGGSVDARSDLFMLGVVLLELATGKNLLFCPDDITPEVMGSLPTKKRRRVARAIKRATLAGAPPLVADAIWRAATL
TAADVDAMTEGLPQGLRVTLNRLLRVAPRERYQSAGESHGLVAHEEASSGRSGNQAGHARRGAAVGGRRDLARGDTDGCG
RRRDD

Specific function: Essential for growth. Interacts with mglA to control social gliding motility [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI19424132, Length=195, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4505373, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI24308326, Length=171, Percent_Identity=24.5614035087719, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI261244921, Length=175, Percent_Identity=28, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI261244925, Length=175, Percent_Identity=28, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI261244929, Length=175, Percent_Identity=28, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI222418622, Length=175, Percent_Identity=28, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI261244927, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI261244923, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI19923407, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI41872673, Length=182, Percent_Identity=29.6703296703297, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994328, Length=162, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI133951912, Length=182, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133951926, Length=182, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325047, Length=177, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649791, Length=166, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008266 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.10.2 [H]

Molecular weight: Translated: 43535; Mature: 43535

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFPQPDAAGSVFLVALVASSHTRGNGMSKAIEFKIPRGAILFSAGGVGYEYREDLGPT
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCC
HHGMALFVARLRTASGAPRGKVLLKAVPAPSETEGARVMRARAKLDEQVRLATFLNHPSI
CCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFPPLFVLYVGAQVAAALEHAHA
EEEECCEEECEEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKDEQGRPLNIVHRAVDVEHVFVNWDGTVQLADFGLALSDLPGRVASSARGPYGDHFYSS
CCCCCCCCHHHHHHHCCEEEEEEECCCEEEEEECCCHHHHCCCHHHHCCCCCCCCCCCCC
PEMLLGGSVDARSDLFMLGVVLLELATGKNLLFCPDDITPEVMGSLPTKKRRRVARAIKR
CCEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCCCHHHHHHHHHHHH
ATLAGAPPLVADAIWRAATLTAADVDAMTEGLPQGLRVTLNRLLRVAPRERYQSAGESHG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCC
LVAHEEASSGRSGNQAGHARRGAAVGGRRDLARGDTDGCGRRRDD
EEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRAFPQPDAAGSVFLVALVASSHTRGNGMSKAIEFKIPRGAILFSAGGVGYEYREDLGPT
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCC
HHGMALFVARLRTASGAPRGKVLLKAVPAPSETEGARVMRARAKLDEQVRLATFLNHPSI
CCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFPPLFVLYVGAQVAAALEHAHA
EEEECCEEECEEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKDEQGRPLNIVHRAVDVEHVFVNWDGTVQLADFGLALSDLPGRVASSARGPYGDHFYSS
CCCCCCCCHHHHHHHCCEEEEEEECCCEEEEEECCCHHHHCCCHHHHCCCCCCCCCCCCC
PEMLLGGSVDARSDLFMLGVVLLELATGKNLLFCPDDITPEVMGSLPTKKRRRVARAIKR
CCEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCCCHHHHHHHHHHHH
ATLAGAPPLVADAIWRAATLTAADVDAMTEGLPQGLRVTLNRLLRVAPRERYQSAGESHG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCC
LVAHEEASSGRSGNQAGHARRGAAVGGRRDLARGDTDGCGRRRDD
EEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2464581 [H]