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The map label for this gene is degP [H]

Identifier: 108761977

GI number: 108761977

Start: 4909347

End: 4910669

Strand: Reverse

Name: degP [H]

Synonym: MXAN_4006

Alternate gene names: 108761977

Gene position: 4910669-4909347 (Counterclockwise)

Preceding gene: 108759057

Following gene: 108759528

Centisome position: 53.73

GC content: 69.84

Gene sequence:

>1323_bases
ATGTTCGCCTTCATCCTCGCAGCGGTGCTCACGCAGTCGCCGGTGGTGCCGGCGGCGCCGAGCCCGCCTCCCGCACCTGG
CACCCCCGAAGCCGTGCCCGCCGTGCCCTTGAGCACGCTGCCACCCGCCACGCACGAGCTGTTCCAGCGCATCGAGGGAC
AGGTCGCGCAGGTGCGCATCATCGAGCGGCGCTCTGGCACGCGCTCGTCCATCGGCTCGGCCTTCTTCGTGTCGGCCGCC
GGGCACGCGGTGACGAACTACCACGTGATTTCCGACGTGGTCATCCACCCGGAGGACTACACGGCGGAGCTGGTCCTGAA
GGGCGGCGCAGAGCCCGTGCCGGTGCGCCTGGTGGACGTGGACGTCGTGCACGACCTGGCCATCATCCAGACGGCCACCC
CGGTGCAGAGCTTCTTCGACCTGGACGACCGCGAGCCGCCGCAGGGCGCGCGCCTGTTCGCCATGGGCAATCCGCGCGAT
CTGGGCACCACCATCGTGGAGGGGACGTACAACGGCTTCATCCACGACGCGCTCTATGAGCGGCTGCACTTCAGCGGGGC
CATCAATCCGGGCATGAGCGGCGGCCCCACGCTCACGGGAGAGGGCCGCGTGGTGGGCGTCAACGTGGCGACCATGGGCA
ACCAGGTGGGCTTTCTGGTGCCGGTGAAGCACGCGCGCGCGCTGCTGGCCCGCGCGCTGGAAGCCAAGGACTCCGGCGCG
CAGGCGCTGCTGGATACCGTGCGCGCGCAGCTCCTGGACAACCAGCAGCGCGTCACCGAAAGGCTGCTGGGCGCGCCCGT
GCCGCAGCAGACGCTGGGCAGCTACCGCGTGCCGGGGCGCTGGGGCACGTTTCTCAAGTGCTGGGGGGACACGCCGCATG
ACCCCGAGGTGCCGTACACGGTGACGAACTACCAGTGCTCGTCGGAGGAGGACATCTTCGTGTCCTCGCGCCACCGGACG
GGCGTGGTGGCCTTCCTGCATCAACACGCCACCAGCCAGAAGCTGGGGGCGCTGCGCTTCTCCGCGCTCTACAGCGCGCT
CTTCTCACAGGACCCGGACGCGGTGGAGGCCACACGGCAGGACGTCACCAACTACCGCTGCCAGTCGGAGTTCGTGGACG
TGGCGGGCCTGCCCGTCCGTGCCGCGCTGTGCATGCGTGCCTACCGGAAGTTCCCCGGCCTCTATGACCTGGTGCTGCGC
GCGGCCACGCTCAATGGCAGCACCAGCGGCGTGGACACGTCGCTCACGCTGGCTGGCTTCACCGCGGACAATGGCCGCAA
GCTGGCGCGCCGCTACCTGGAGGGGCTGTCGTGGACGAAGTAA

Upstream 100 bases:

>100_bases
CGCGTCGGTGGGTGGACGGACCGCCCGGCCGCCTGCCTGGCGCGAGACATGAGGCTGCACGTCCGTCGGAGGGCGCGGTG
GGGTAGGGTGCGCCGCATCC

Downstream 100 bases:

>100_bases
TCTTCCTGGAGGTGTTGGAAGGGGACTCCGTCCAGGCCCGTCATCGCCTGGAGCGCTTCCCCGTCAACGTCGGCCGGGGT
TACGGCAACGACGTCATCCT

Product: S1C family peptidase

Products: NA

Alternate protein names: Antigen htrA [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MFAFILAAVLTQSPVVPAAPSPPPAPGTPEAVPAVPLSTLPPATHELFQRIEGQVAQVRIIERRSGTRSSIGSAFFVSAA
GHAVTNYHVISDVVIHPEDYTAELVLKGGAEPVPVRLVDVDVVHDLAIIQTATPVQSFFDLDDREPPQGARLFAMGNPRD
LGTTIVEGTYNGFIHDALYERLHFSGAINPGMSGGPTLTGEGRVVGVNVATMGNQVGFLVPVKHARALLARALEAKDSGA
QALLDTVRAQLLDNQQRVTERLLGAPVPQQTLGSYRVPGRWGTFLKCWGDTPHDPEVPYTVTNYQCSSEEDIFVSSRHRT
GVVAFLHQHATSQKLGALRFSALYSALFSQDPDAVEATRQDVTNYRCQSEFVDVAGLPVRAALCMRAYRKFPGLYDLVLR
AATLNGSTSGVDTSLTLAGFTADNGRKLARRYLEGLSWTK

Sequences:

>Translated_440_residues
MFAFILAAVLTQSPVVPAAPSPPPAPGTPEAVPAVPLSTLPPATHELFQRIEGQVAQVRIIERRSGTRSSIGSAFFVSAA
GHAVTNYHVISDVVIHPEDYTAELVLKGGAEPVPVRLVDVDVVHDLAIIQTATPVQSFFDLDDREPPQGARLFAMGNPRD
LGTTIVEGTYNGFIHDALYERLHFSGAINPGMSGGPTLTGEGRVVGVNVATMGNQVGFLVPVKHARALLARALEAKDSGA
QALLDTVRAQLLDNQQRVTERLLGAPVPQQTLGSYRVPGRWGTFLKCWGDTPHDPEVPYTVTNYQCSSEEDIFVSSRHRT
GVVAFLHQHATSQKLGALRFSALYSALFSQDPDAVEATRQDVTNYRCQSEFVDVAGLPVRAALCMRAYRKFPGLYDLVLR
AATLNGSTSGVDTSLTLAGFTADNGRKLARRYLEGLSWTK
>Mature_440_residues
MFAFILAAVLTQSPVVPAAPSPPPAPGTPEAVPAVPLSTLPPATHELFQRIEGQVAQVRIIERRSGTRSSIGSAFFVSAA
GHAVTNYHVISDVVIHPEDYTAELVLKGGAEPVPVRLVDVDVVHDLAIIQTATPVQSFFDLDDREPPQGARLFAMGNPRD
LGTTIVEGTYNGFIHDALYERLHFSGAINPGMSGGPTLTGEGRVVGVNVATMGNQVGFLVPVKHARALLARALEAKDSGA
QALLDTVRAQLLDNQQRVTERLLGAPVPQQTLGSYRVPGRWGTFLKCWGDTPHDPEVPYTVTNYQCSSEEDIFVSSRHRT
GVVAFLHQHATSQKLGALRFSALYSALFSQDPDAVEATRQDVTNYRCQSEFVDVAGLPVRAALCMRAYRKFPGLYDLVLR
AATLNGSTSGVDTSLTLAGFTADNGRKLARRYLEGLSWTK

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 47436; Mature: 47436

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAFILAAVLTQSPVVPAAPSPPPAPGTPEAVPAVPLSTLPPATHELFQRIEGQVAQVRI
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
IERRSGTRSSIGSAFFVSAAGHAVTNYHVISDVVIHPEDYTAELVLKGGAEPVPVRLVDV
EECCCCCCHHCCCEEEEECCCCHHEEEEEEEEEEECCCCCCEEEEEECCCCCCCEEEEEH
DVVHDLAIIQTATPVQSFFDLDDREPPQGARLFAMGNPRDLGTTIVEGTYNGFIHDALYE
HHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEECCCCCCHHHHHHHH
RLHFSGAINPGMSGGPTLTGEGRVVGVNVATMGNQVGFLVPVKHARALLARALEAKDSGA
HHHHCCCCCCCCCCCCEECCCCEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCHH
QALLDTVRAQLLDNQQRVTERLLGAPVPQQTLGSYRVPGRWGTFLKCWGDTPHDPEVPYT
HHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCEECCCCCCCEEEEECCCCCCCCCCEE
VTNYQCSSEEDIFVSSRHRTGVVAFLHQHATSQKLGALRFSALYSALFSQDPDAVEATRQ
EECEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DVTNYRCQSEFVDVAGLPVRAALCMRAYRKFPGLYDLVLRAATLNGSTSGVDTSLTLAGF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEE
TADNGRKLARRYLEGLSWTK
ECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFAFILAAVLTQSPVVPAAPSPPPAPGTPEAVPAVPLSTLPPATHELFQRIEGQVAQVRI
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
IERRSGTRSSIGSAFFVSAAGHAVTNYHVISDVVIHPEDYTAELVLKGGAEPVPVRLVDV
EECCCCCCHHCCCEEEEECCCCHHEEEEEEEEEEECCCCCCEEEEEECCCCCCCEEEEEH
DVVHDLAIIQTATPVQSFFDLDDREPPQGARLFAMGNPRDLGTTIVEGTYNGFIHDALYE
HHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEECCCCCCHHHHHHHH
RLHFSGAINPGMSGGPTLTGEGRVVGVNVATMGNQVGFLVPVKHARALLARALEAKDSGA
HHHHCCCCCCCCCCCCEECCCCEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCHH
QALLDTVRAQLLDNQQRVTERLLGAPVPQQTLGSYRVPGRWGTFLKCWGDTPHDPEVPYT
HHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCEECCCCCCCEEEEECCCCCCCCCCEE
VTNYQCSSEEDIFVSSRHRTGVVAFLHQHATSQKLGALRFSALYSALFSQDPDAVEATRQ
EECEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DVTNYRCQSEFVDVAGLPVRAALCMRAYRKFPGLYDLVLRAATLNGSTSGVDTSLTLAGF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEE
TADNGRKLARRYLEGLSWTK
ECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8027347 [H]