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The map label for this gene is agmH [H]

Identifier: 108761899

GI number: 108761899

Start: 5817792

End: 5818631

Strand: Reverse

Name: agmH [H]

Synonym: MXAN_4638

Alternate gene names: 108761899

Gene position: 5818631-5817792 (Counterclockwise)

Preceding gene: 108757730

Following gene: 108763141

Centisome position: 63.66

GC content: 68.45

Gene sequence:

>840_bases
ATGGCGCGTAGCGACGAGGGCTTCTTTCCCGGCAGGGACGGGACACGACTGTACTGGAAGTCCATCCTTCCAGACGCCGA
GCCTCGCGCGCATGTCGCGGTGGTGCACGGGTATGGTGACCACTTCGGGCGCTATGGCTTCGTGACGGACGCACTGCTGG
CGGACGGCTTCGCGGTCCACGGCTTCGACTACCGGGGCCACGGTAAGGCCGACGGGCGCCGGGCCTACTGTGAGAAGTGG
CCGGACTACCTGGAGGACCTGGAGGTCTTCTGGGAGCGGGTGCGCGCGGTGTCGGAGGGCAAGAAGGCCTTCGTGCTGGC
GCACAGCCACGGCGGCCTGATGTCGGCGACGTGGGCTTCCAGCCGGCGGGTGGAGGGGTTGACGGGGCTGGTGCTGTCGG
CGCCGTACCTCAAGCTGGCCATCACCCCTCCGGCCTCGAAGCTGATGGCCGCGCGCGCGGTGGGCAAGCTGGTGCCATGG
CTGAGCATCTCCTCCGGACTGAAGGTGGAGGACCTCACCCATGACACCGACGTGCAGCGGGCCACCCGGGAGGACCCGCT
CCATCAGGCCATCGCCACGCCACGGTGGTTCGTCGAATCCACCCGGGCGCAGGGTGAGGCCGTGCTGCTGGCGCCGAAGA
TTCAAGTGCCGCTGTTCGTCCTGTGTGGCGCGGAGGATGGGGTGGCCGCTCCGGCGGCGGCGCGGGAGTACTTCGAGCGG
GCGGGGTCGCCGGACAAGAAGTTCAAGGAGTACCCCGGAATGCGGCATGAGCCGCTCAACGAGGTGGGCCGTGCGGAGGT
ATTCCGGGATATCTCCGGCTGGATCTCCGCGCATCTCTGA

Upstream 100 bases:

>100_bases
GGATCCTGAGTCCGCCGAGCCACCCGGCCAGCGCGCCGCGTTGGAGCGCAAGCTCAATGCGCTACCCACGCGTGCGCCAG
ACCGCTAAGTTGGTGGGCCT

Downstream 100 bases:

>100_bases
CATAATCAGGTCGCCCGGCTCCTAGGGAGGAGCTGGCGCTGGGTGAGGTCACCGCATGGCAACGGGTGAAACGGGCATCA
TCGGCAAGGGCATCGTCATC

Product: lysophospholipase AgmH

Products: NA

Alternate protein names: Bacilysocin biosynthesis protein ytpA [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MARSDEGFFPGRDGTRLYWKSILPDAEPRAHVAVVHGYGDHFGRYGFVTDALLADGFAVHGFDYRGHGKADGRRAYCEKW
PDYLEDLEVFWERVRAVSEGKKAFVLAHSHGGLMSATWASSRRVEGLTGLVLSAPYLKLAITPPASKLMAARAVGKLVPW
LSISSGLKVEDLTHDTDVQRATREDPLHQAIATPRWFVESTRAQGEAVLLAPKIQVPLFVLCGAEDGVAAPAAAREYFER
AGSPDKKFKEYPGMRHEPLNEVGRAEVFRDISGWISAHL

Sequences:

>Translated_279_residues
MARSDEGFFPGRDGTRLYWKSILPDAEPRAHVAVVHGYGDHFGRYGFVTDALLADGFAVHGFDYRGHGKADGRRAYCEKW
PDYLEDLEVFWERVRAVSEGKKAFVLAHSHGGLMSATWASSRRVEGLTGLVLSAPYLKLAITPPASKLMAARAVGKLVPW
LSISSGLKVEDLTHDTDVQRATREDPLHQAIATPRWFVESTRAQGEAVLLAPKIQVPLFVLCGAEDGVAAPAAAREYFER
AGSPDKKFKEYPGMRHEPLNEVGRAEVFRDISGWISAHL
>Mature_278_residues
ARSDEGFFPGRDGTRLYWKSILPDAEPRAHVAVVHGYGDHFGRYGFVTDALLADGFAVHGFDYRGHGKADGRRAYCEKWP
DYLEDLEVFWERVRAVSEGKKAFVLAHSHGGLMSATWASSRRVEGLTGLVLSAPYLKLAITPPASKLMAARAVGKLVPWL
SISSGLKVEDLTHDTDVQRATREDPLHQAIATPRWFVESTRAQGEAVLLAPKIQVPLFVLCGAEDGVAAPAAAREYFERA
GSPDKKFKEYPGMRHEPLNEVGRAEVFRDISGWISAHL

Specific function: Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis react

COG id: COG2267

COG function: function code I; Lysophospholipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI51242953, Length=272, Percent_Identity=27.9411764705882, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI6005786, Length=272, Percent_Identity=27.9411764705882, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1787678, Length=275, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR022742 [H]

Pfam domain/function: PF12146 Hydrolase_4 [H]

EC number: NA

Molecular weight: Translated: 30813; Mature: 30682

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00697 DNA_LIGASE_A1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSDEGFFPGRDGTRLYWKSILPDAEPRAHVAVVHGYGDHFGRYGFVTDALLADGFAVH
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCHHCCCHHHHHHHHHCCEEEE
GFDYRGHGKADGRRAYCEKWPDYLEDLEVFWERVRAVSEGKKAFVLAHSHGGLMSATWAS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEHHCC
SRRVEGLTGLVLSAPYLKLAITPPASKLMAARAVGKLVPWLSISSGLKVEDLTHDTDVQR
CCCCCCHHHHEEECCEEEEEECCCHHHHHHHHHHHHHHCHHCCCCCCEEECCCCCHHHHH
ATREDPLHQAIATPRWFVESTRAQGEAVLLAPKIQVPLFVLCGAEDGVAAPAAAREYFER
HHHCCHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHH
AGSPDKKFKEYPGMRHEPLNEVGRAEVFRDISGWISAHL
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARSDEGFFPGRDGTRLYWKSILPDAEPRAHVAVVHGYGDHFGRYGFVTDALLADGFAVH
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCHHCCCHHHHHHHHHCCEEEE
GFDYRGHGKADGRRAYCEKWPDYLEDLEVFWERVRAVSEGKKAFVLAHSHGGLMSATWAS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEHHCC
SRRVEGLTGLVLSAPYLKLAITPPASKLMAARAVGKLVPWLSISSGLKVEDLTHDTDVQR
CCCCCCHHHHEEECCEEEEEECCCHHHHHHHHHHHHHHCHHCCCCCCEEECCCCCHHHHH
ATREDPLHQAIATPRWFVESTRAQGEAVLLAPKIQVPLFVLCGAEDGVAAPAAAREYFER
HHHCCHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHH
AGSPDKKFKEYPGMRHEPLNEVGRAEVFRDISGWISAHL
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]