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The map label for this gene is zraR [H]

Identifier: 108761825

GI number: 108761825

Start: 6947304

End: 6947972

Strand: Direct

Name: zraR [H]

Synonym: MXAN_5592

Alternate gene names: 108761825

Gene position: 6947304-6947972 (Clockwise)

Preceding gene: 108764009

Following gene: 108759435

Centisome position: 76.01

GC content: 64.57

Gene sequence:

>669_bases
GTGGTCTGCCGGAATCACCCTCGCCCCCCGGGGGTATTCCGGTCCCATGGCACTGAACTGCAGCGAGGAGACGCTGTGCA
GATTCGCATCCTGGTAGTTGATGATGAGCAGGACAACTGCGACTACCTCAAGCTGGTCCTGACCCGTGAAGGCTACGAGG
TCGTGACCACGACGGACCCCACCCAGACGGTGGAAATCCTCCGGGGCTCCGACTTCCACCTCGTCATCCTCGACATGATG
ATGCCGCAGATGTCGGGCACCGAGGTGCTGGAGCAGATTCGCAAGTACGACACGGACGTGGCCGTCATCGTCGCCACCGC
GTACCCCACGGTGGACACGGCGGTGGCCTCGCTCAAGGCGCAGGCTTCCGACTACGTCAAGAAGCCCATGGAGCCGGAGC
AGTTCATCACCGCGGTCCGCAACGCCCTCCAGAAGAAGGGCTTGTCCCAGGACCCGGAGGCGGACCTGCACCGCGCCATT
GGCCGCACCATCCGCGACGCACGCAAGACGCAGGAGCTCACGCTCAAGCAACTGGCGCGGCGCACGGGCCTGTCGGTGTC
GCTGCTGTCGCAGATTGAGCGCGCGGAGTCCTCCGCCTCCATCTCCTCGCTGTACAAGATTGCCTCGGCCCTGCAACTGC
GCATGGGCGAGCTCTTCGGCGATACCTGA

Upstream 100 bases:

>100_bases
GCGCGGTTCACTACAAGCGATTCCTGGAACTTGCGCCCAATCACGCGTACTACGAGCGCGTGAAGGGTTTGGTCGAGAGT
TACGAGAATCCCAAGAAGTA

Downstream 100 bases:

>100_bases
TGTCGCCGTGGCAGTGCCCCGCCGGCCGCCCTGACTAGCGGCCGGAGAAGCGGGGCGGGCGCTTTTCAAGGAAGGCCGCC
CGCCCCTCCTTCGCGTCCTC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MVCRNHPRPPGVFRSHGTELQRGDAVQIRILVVDDEQDNCDYLKLVLTREGYEVVTTTDPTQTVEILRGSDFHLVILDMM
MPQMSGTEVLEQIRKYDTDVAVIVATAYPTVDTAVASLKAQASDYVKKPMEPEQFITAVRNALQKKGLSQDPEADLHRAI
GRTIRDARKTQELTLKQLARRTGLSVSLLSQIERAESSASISSLYKIASALQLRMGELFGDT

Sequences:

>Translated_222_residues
MVCRNHPRPPGVFRSHGTELQRGDAVQIRILVVDDEQDNCDYLKLVLTREGYEVVTTTDPTQTVEILRGSDFHLVILDMM
MPQMSGTEVLEQIRKYDTDVAVIVATAYPTVDTAVASLKAQASDYVKKPMEPEQFITAVRNALQKKGLSQDPEADLHRAI
GRTIRDARKTQELTLKQLARRTGLSVSLLSQIERAESSASISSLYKIASALQLRMGELFGDT
>Mature_222_residues
MVCRNHPRPPGVFRSHGTELQRGDAVQIRILVVDDEQDNCDYLKLVLTREGYEVVTTTDPTQTVEILRGSDFHLVILDMM
MPQMSGTEVLEQIRKYDTDVAVIVATAYPTVDTAVASLKAQASDYVKKPMEPEQFITAVRNALQKKGLSQDPEADLHRAI
GRTIRDARKTQELTLKQLARRTGLSVSLLSQIERAESSASISSLYKIASALQLRMGELFGDT

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=35.8974358974359, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=32.8358208955224, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=27.1186440677966, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1790863, Length=116, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=29.6610169491525, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=146, Percent_Identity=28.7671232876712, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788905, Length=122, Percent_Identity=30.327868852459, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 24733; Mature: 24733

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCRNHPRPPGVFRSHGTELQRGDAVQIRILVVDDEQDNCDYLKLVLTREGYEVVTTTDP
CCCCCCCCCCCCHHCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCCEEEEECCC
TQTVEILRGSDFHLVILDMMMPQMSGTEVLEQIRKYDTDVAVIVATAYPTVDTAVASLKA
HHHHHHHCCCCCCEEHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
QASDYVKKPMEPEQFITAVRNALQKKGLSQDPEADLHRAIGRTIRDARKTQELTLKQLAR
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGLSVSLLSQIERAESSASISSLYKIASALQLRMGELFGDT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVCRNHPRPPGVFRSHGTELQRGDAVQIRILVVDDEQDNCDYLKLVLTREGYEVVTTTDP
CCCCCCCCCCCCHHCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCCEEEEECCC
TQTVEILRGSDFHLVILDMMMPQMSGTEVLEQIRKYDTDVAVIVATAYPTVDTAVASLKA
HHHHHHHCCCCCCEEHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
QASDYVKKPMEPEQFITAVRNALQKKGLSQDPEADLHRAIGRTIRDARKTQELTLKQLAR
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGLSVSLLSQIERAESSASISSLYKIASALQLRMGELFGDT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]