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The map label for this gene is fabF [H]

Identifier: 108761812

GI number: 108761812

Start: 5968613

End: 5969866

Strand: Reverse

Name: fabF [H]

Synonym: MXAN_4768

Alternate gene names: 108761812

Gene position: 5969866-5968613 (Counterclockwise)

Preceding gene: 108761267

Following gene: 108758725

Centisome position: 65.32

GC content: 66.43

Gene sequence:

>1254_bases
GTGTCACAACGTCGAGTCGTCGTCACCGGAACCGGGCTTGTTTCGGCTCTGGGAACCGGAACCGAGAAGAACTGGCAGGC
GTTGATCGCCGGCAAGTCGGGTATTGCCCAGGTCACGCGCTTTGACGTTGGCAAAATCGACACGCGCATCGCGGGCGAGG
TGAAGGACTTCGAGCCCGAGGCGTTCATCGAAAAGCGCGAAGTGCGCCGGATGGACCTGTATGCGCAGTTCGCGTTGGCC
GCCGCGCAGATGGCCGTGACGGAGTCGGGCATTCCCATTGGCCCGGATGCTCCGCACGGCTACATCCCGGAGAAGGTCGG
CGTCATCGTCGGCTCGGGCATCGGCGGTATCTCTTCGCTGGAAGAGCAGCACCGCAAGGGGTTGGAGAAGGGGTTCGACC
GGTTGTCGCCCTTCTTCATCATCCAGATGATCATCAACATGGCGCCGGGCCTCATCTCCATGCGGTACAACTGCAAGGGG
CCGAACTGGGCGCCGGTGTCCGCGTGTGCCACCAGTGCCCACGCCATTGGCGAGGCCTGGAAGTCCATCCGCCTGGGTGA
GACGGACGCGGTCATCGCCGGCGGCGCCGAGGCGGCCATCACCCCGTTGGGGCTGGGTGGCTTCTCGGTGATGAAGGCGC
TGTCCACACGCAATGATGATCCGGCCGGGGCCAGCCGTCCCTTCGACAAGGACCGTGACGGCTTCGTCATGGGCGAGGGC
GCGGGCATCCTGGTGCTGGAGGAGATGGAGGCCGCGAAGAAGCGCGGCGCCAACATCCTCGCGGAGGTGGTGGGGTACGG
TGCCAACTCGGACGCGTACCACGTCACCCAGCCGGCGCCGGAAGGCGAGGGCGCGGCGCGCTGCATGCGGCTGGCGCTCC
AGTCCGCGGGGATGAACCCGGAGGACGTGGGCTACATCAACGCTCACGGCACCTCGACGCCGTTCAACGACGCGAATGAG
ACGAAGGCCATCAAGACGGTGTTCGGCGACCACGCGCGGAAGATCGCCGTGTCGTCGACCAAGTCGATGACGGGCCACAT
GCTCGGCGCGGCGGGCGGCTTCGAGGGCGTGGTCAGCGCGCTGGCGCTGGCGCGCAACATCCTGCCGCCCACCATCAACC
AGACGACGCCTGATCCGGACTGCGACCTGGACTACGTGCCCAACCAGGCGCGTGAGGCCCGGGTGGACGCGGTGATGAGC
AACTCGTTTGGCTTCGGCGGCACCAACGCCGTGCTGGTGTTCAAGCGCTTCTAG

Upstream 100 bases:

>100_bases
CACCCACAAGAAGTAGGTAGCACCACGGCGTGCCGGGGTGCGGGGCGGCGCCGCGTGATGCGCGGCGTCCCCGGTGTCCC
AGGCGCCACCGGAGAGGACC

Downstream 100 bases:

>100_bases
CTGTCTCAGGAGAAACCCGCGTGAAAGTCATCCTCGCTTCAGACCACGCGGGACTGGAGCTCCGGCAGGAGCTGGTGGCC
GCGCTCACCGCGCGGGGCGT

Product: beta-ketoacyl-acyl carrier protein synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSQRRVVVTGTGLVSALGTGTEKNWQALIAGKSGIAQVTRFDVGKIDTRIAGEVKDFEPEAFIEKREVRRMDLYAQFALA
AAQMAVTESGIPIGPDAPHGYIPEKVGVIVGSGIGGISSLEEQHRKGLEKGFDRLSPFFIIQMIINMAPGLISMRYNCKG
PNWAPVSACATSAHAIGEAWKSIRLGETDAVIAGGAEAAITPLGLGGFSVMKALSTRNDDPAGASRPFDKDRDGFVMGEG
AGILVLEEMEAAKKRGANILAEVVGYGANSDAYHVTQPAPEGEGAARCMRLALQSAGMNPEDVGYINAHGTSTPFNDANE
TKAIKTVFGDHARKIAVSSTKSMTGHMLGAAGGFEGVVSALALARNILPPTINQTTPDPDCDLDYVPNQAREARVDAVMS
NSFGFGGTNAVLVFKRF

Sequences:

>Translated_417_residues
MSQRRVVVTGTGLVSALGTGTEKNWQALIAGKSGIAQVTRFDVGKIDTRIAGEVKDFEPEAFIEKREVRRMDLYAQFALA
AAQMAVTESGIPIGPDAPHGYIPEKVGVIVGSGIGGISSLEEQHRKGLEKGFDRLSPFFIIQMIINMAPGLISMRYNCKG
PNWAPVSACATSAHAIGEAWKSIRLGETDAVIAGGAEAAITPLGLGGFSVMKALSTRNDDPAGASRPFDKDRDGFVMGEG
AGILVLEEMEAAKKRGANILAEVVGYGANSDAYHVTQPAPEGEGAARCMRLALQSAGMNPEDVGYINAHGTSTPFNDANE
TKAIKTVFGDHARKIAVSSTKSMTGHMLGAAGGFEGVVSALALARNILPPTINQTTPDPDCDLDYVPNQAREARVDAVMS
NSFGFGGTNAVLVFKRF
>Mature_416_residues
SQRRVVVTGTGLVSALGTGTEKNWQALIAGKSGIAQVTRFDVGKIDTRIAGEVKDFEPEAFIEKREVRRMDLYAQFALAA
AQMAVTESGIPIGPDAPHGYIPEKVGVIVGSGIGGISSLEEQHRKGLEKGFDRLSPFFIIQMIINMAPGLISMRYNCKGP
NWAPVSACATSAHAIGEAWKSIRLGETDAVIAGGAEAAITPLGLGGFSVMKALSTRNDDPAGASRPFDKDRDGFVMGEGA
GILVLEEMEAAKKRGANILAEVVGYGANSDAYHVTQPAPEGEGAARCMRLALQSAGMNPEDVGYINAHGTSTPFNDANET
KAIKTVFGDHARKIAVSSTKSMTGHMLGAAGGFEGVVSALALARNILPPTINQTTPDPDCDLDYVPNQAREARVDAVMSN
SFGFGGTNAVLVFKRF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=421, Percent_Identity=46.3182897862233, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI223972627, Length=168, Percent_Identity=50.5952380952381, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI41872631, Length=380, Percent_Identity=27.3684210526316, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1787337, Length=418, Percent_Identity=49.7607655502392, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1788663, Length=418, Percent_Identity=38.0382775119617, Blast_Score=254, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71983541, Length=424, Percent_Identity=36.7924528301887, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71983535, Length=256, Percent_Identity=44.921875, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI212642053, Length=365, Percent_Identity=27.6712328767123, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=280, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=448, Percent_Identity=34.1517857142857, Blast_Score=255, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6325025, Length=234, Percent_Identity=29.0598290598291, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24644341, Length=423, Percent_Identity=42.789598108747, Blast_Score=333, Evalue=9e-92,
Organism=Drosophila melanogaster, GI19920632, Length=382, Percent_Identity=26.7015706806283, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221330659, Length=382, Percent_Identity=26.7015706806283, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24581345, Length=414, Percent_Identity=24.1545893719807, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43914; Mature: 43783

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRRVVVTGTGLVSALGTGTEKNWQALIAGKSGIAQVTRFDVGKIDTRIAGEVKDFEPE
CCCCEEEEECCHHHHHHCCCCCCCCEEEEECCCCHHHHHHCCCCCCCHHHCCCCCCCCHH
AFIEKREVRRMDLYAQFALAAAQMAVTESGIPIGPDAPHGYIPEKVGVIVGSGIGGISSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCEEEECCCCCHHHH
EEQHRKGLEKGFDRLSPFFIIQMIINMAPGLISMRYNCKGPNWAPVSACATSAHAIGEAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
KSIRLGETDAVIAGGAEAAITPLGLGGFSVMKALSTRNDDPAGASRPFDKDRDGFVMGEG
HHCCCCCCCEEEECCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC
AGILVLEEMEAAKKRGANILAEVVGYGANSDAYHVTQPAPEGEGAARCMRLALQSAGMNP
CCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCH
EDVGYINAHGTSTPFNDANETKAIKTVFGDHARKIAVSSTKSMTGHMLGAAGGFEGVVSA
HHCEEEECCCCCCCCCCCCHHHHHHHHHCCHHHEEEECCCHHHHHHHHCCCCCHHHHHHH
LALARNILPPTINQTTPDPDCDLDYVPNQAREARVDAVMSNSFGFGGTNAVLVFKRF
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
SQRRVVVTGTGLVSALGTGTEKNWQALIAGKSGIAQVTRFDVGKIDTRIAGEVKDFEPE
CCCEEEEECCHHHHHHCCCCCCCCEEEEECCCCHHHHHHCCCCCCCHHHCCCCCCCCHH
AFIEKREVRRMDLYAQFALAAAQMAVTESGIPIGPDAPHGYIPEKVGVIVGSGIGGISSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCEEEECCCCCHHHH
EEQHRKGLEKGFDRLSPFFIIQMIINMAPGLISMRYNCKGPNWAPVSACATSAHAIGEAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
KSIRLGETDAVIAGGAEAAITPLGLGGFSVMKALSTRNDDPAGASRPFDKDRDGFVMGEG
HHCCCCCCCEEEECCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC
AGILVLEEMEAAKKRGANILAEVVGYGANSDAYHVTQPAPEGEGAARCMRLALQSAGMNP
CCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCH
EDVGYINAHGTSTPFNDANETKAIKTVFGDHARKIAVSSTKSMTGHMLGAAGGFEGVVSA
HHCEEEECCCCCCCCCCCCHHHHHHHHHCCHHHEEEECCCHHHHHHHHCCCCCHHHHHHH
LALARNILPPTINQTTPDPDCDLDYVPNQAREARVDAVMSNSFGFGGTNAVLVFKRF
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]