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The map label for this gene is degS [H]

Identifier: 108761766

GI number: 108761766

Start: 349748

End: 350689

Strand: Reverse

Name: degS [H]

Synonym: MXAN_0296

Alternate gene names: 108761766

Gene position: 350689-349748 (Counterclockwise)

Preceding gene: 108761852

Following gene: 108759219

Centisome position: 3.84

GC content: 71.02

Gene sequence:

>942_bases
GTGGCGCCTTTTCGAGGCCTTTACCTTGTGCCTCGAAAGGAACACACCATGTCCACCGGCCTCCTCCAGTCGCTGTCCCA
CTCCCTCGCCTCCATCGTCGAGCGCACCGCGCCTGGCATCGTCCGCGTGGAGACGCGGCGCAGGCGCGGCACCACCGGCA
TCGTCTGGGATGCCGAGGGCCACATCCTCACCACCAGCCAGGCCGTGGAGCACGAGGGCCGGCTCCCTATCGGCTTGCCG
GATGGCCGCACCGTCTCCGCCGAGTTCGTCGGCCGCGACGCCAGCACCGACCTGGCCCTGCTCAAGGCCGAAGCCACCGG
CCTCGCGCCGCTGACCTCCGCGCCGTTGGATGACGTGAAGGTCGGTCACCTCGTCATCGCCGTGGGCCGCCCTGGCCGCA
CGGCTCGCGCGACGCTCGGCATGGTCAGCACCCACGGCGAGGGCTGGCGCACCCATGCCGGAGGCCGCGTGGAGCGCTAC
CTGGAGACGGATGCCGACCTCCCGCCCGGCTTCTCCGGCGGCGCGCTGGTGGACACCGAGGGACGCCTTGTCGGTCTGCT
CACCGCCGCCTTCTCTCGCACCGCCGCCGTCGTCATCGCCACGGACACGCTCACGCGCGTGATTGCATCGCTGAAGGAAC
ACGGGGGCATCCGGCGTGGCTACCTGGGCGTGGGCGCCTACCCCGTGCGTCTGCCCCCACACCTGGGCACGGGGAACGAA
CACGGCCTCATCTGCCTCTCCGTGGACCCGAACGGCCCGGCGCATGACGCGGGTCTGCTGCTCGGAGACGTCCTGGTGAG
TCTGGGAGGTCAGCCCCTCCACGGCGTGGAGGACCTGCTCGGAGCCCTGAGCGACGAGAAGGTGGGCACCACCCTCCAGG
TCCGCGTGCTGCGCGCCGGAGAGGTTCGCGAAGTGCCCATCACCGTGGGCAAGCGCTCGTGA

Upstream 100 bases:

>100_bases
ACCTGGAAGCGCGCTACGAGCGTTTCCGCATGACAGGCTGAACCAAAGACGAGGTGACCTCCCCGAATGGGGAGGTTCCC
GACCTGACCGGTCCGCCGAT

Downstream 100 bases:

>100_bases
AGGGAGGCCACCGTGAAACTGCTGCAACACTTCTCGGATGATTTGGAGTCGCTGGTGGCGCGTGCCTCGCCCGCCGTCGT
GGGCGTGGAGCACGCACGCG

Product: S1C family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAPFRGLYLVPRKEHTMSTGLLQSLSHSLASIVERTAPGIVRVETRRRRGTTGIVWDAEGHILTTSQAVEHEGRLPIGLP
DGRTVSAEFVGRDASTDLALLKAEATGLAPLTSAPLDDVKVGHLVIAVGRPGRTARATLGMVSTHGEGWRTHAGGRVERY
LETDADLPPGFSGGALVDTEGRLVGLLTAAFSRTAAVVIATDTLTRVIASLKEHGGIRRGYLGVGAYPVRLPPHLGTGNE
HGLICLSVDPNGPAHDAGLLLGDVLVSLGGQPLHGVEDLLGALSDEKVGTTLQVRVLRAGEVREVPITVGKRS

Sequences:

>Translated_313_residues
MAPFRGLYLVPRKEHTMSTGLLQSLSHSLASIVERTAPGIVRVETRRRRGTTGIVWDAEGHILTTSQAVEHEGRLPIGLP
DGRTVSAEFVGRDASTDLALLKAEATGLAPLTSAPLDDVKVGHLVIAVGRPGRTARATLGMVSTHGEGWRTHAGGRVERY
LETDADLPPGFSGGALVDTEGRLVGLLTAAFSRTAAVVIATDTLTRVIASLKEHGGIRRGYLGVGAYPVRLPPHLGTGNE
HGLICLSVDPNGPAHDAGLLLGDVLVSLGGQPLHGVEDLLGALSDEKVGTTLQVRVLRAGEVREVPITVGKRS
>Mature_312_residues
APFRGLYLVPRKEHTMSTGLLQSLSHSLASIVERTAPGIVRVETRRRRGTTGIVWDAEGHILTTSQAVEHEGRLPIGLPD
GRTVSAEFVGRDASTDLALLKAEATGLAPLTSAPLDDVKVGHLVIAVGRPGRTARATLGMVSTHGEGWRTHAGGRVERYL
ETDADLPPGFSGGALVDTEGRLVGLLTAAFSRTAAVVIATDTLTRVIASLKEHGGIRRGYLGVGAYPVRLPPHLGTGNEH
GLICLSVDPNGPAHDAGLLLGDVLVSLGGQPLHGVEDLLGALSDEKVGTTLQVRVLRAGEVREVPITVGKRS

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=317, Percent_Identity=26.1829652996845, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI24308541, Length=310, Percent_Identity=25.4838709677419, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7019477, Length=313, Percent_Identity=27.4760383386581, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI22129776, Length=290, Percent_Identity=25.5172413793103, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789630, Length=310, Percent_Identity=29.3548387096774, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786356, Length=273, Percent_Identity=28.9377289377289, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789629, Length=268, Percent_Identity=29.4776119402985, Blast_Score=109, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646839, Length=315, Percent_Identity=25.0793650793651, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011783
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 32828; Mature: 32697

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPFRGLYLVPRKEHTMSTGLLQSLSHSLASIVERTAPGIVRVETRRRRGTTGIVWDAEG
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCC
HILTTSQAVEHEGRLPIGLPDGRTVSAEFVGRDASTDLALLKAEATGLAPLTSAPLDDVK
CEEECCHHHHCCCCCCEECCCCCEEEHHEECCCCCCCEEEEEECCCCCCCCCCCCCCCEE
VGHLVIAVGRPGRTARATLGMVSTHGEGWRTHAGGRVERYLETDADLPPGFSGGALVDTE
EEEEEEEECCCCCCHHEEEEEEEECCCCCEECCCCHHHHHHHCCCCCCCCCCCCEEEECC
GRLVGLLTAAFSRTAAVVIATDTLTRVIASLKEHGGIRRGYLGVGAYPVRLPPHLGTGNE
CCEEEHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCEECEECCCCEEEECCCCCCCCCC
HGLICLSVDPNGPAHDAGLLLGDVLVSLGGQPLHGVEDLLGALSDEKVGTTLQVRVLRAG
CCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECC
EVREVPITVGKRS
CEEEEEEEECCCC
>Mature Secondary Structure 
APFRGLYLVPRKEHTMSTGLLQSLSHSLASIVERTAPGIVRVETRRRRGTTGIVWDAEG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCC
HILTTSQAVEHEGRLPIGLPDGRTVSAEFVGRDASTDLALLKAEATGLAPLTSAPLDDVK
CEEECCHHHHCCCCCCEECCCCCEEEHHEECCCCCCCEEEEEECCCCCCCCCCCCCCCEE
VGHLVIAVGRPGRTARATLGMVSTHGEGWRTHAGGRVERYLETDADLPPGFSGGALVDTE
EEEEEEEECCCCCCHHEEEEEEEECCCCCEECCCCHHHHHHHCCCCCCCCCCCCEEEECC
GRLVGLLTAAFSRTAAVVIATDTLTRVIASLKEHGGIRRGYLGVGAYPVRLPPHLGTGNE
CCEEEHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCEECEECCCCEEEECCCCCCCCCC
HGLICLSVDPNGPAHDAGLLLGDVLVSLGGQPLHGVEDLLGALSDEKVGTTLQVRVLRAG
CCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECC
EVREVPITVGKRS
CEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]