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The map label for this gene is degP [H]

Identifier: 108761691

GI number: 108761691

Start: 1069625

End: 1071127

Strand: Reverse

Name: degP [H]

Synonym: MXAN_0934

Alternate gene names: 108761691

Gene position: 1071127-1069625 (Counterclockwise)

Preceding gene: 108763352

Following gene: 108757330

Centisome position: 11.72

GC content: 73.25

Gene sequence:

>1503_bases
ATGGCCTGCTCGCTCCCCTCCCGCCGCTTCCTCAGTGCGCTGGTCCTTCTTCCCGCCGCCACGCTTGGCGCTTGTGGCCA
AGCCATTGGCACCGCGTCCGCGGCATCGCCCGCTCCCACCGCCCAGGTCGCCGCCGCTGTTCCGGCGCAGGCGGCGCCGC
CCATCCAGAAGGCGCTCTTCAATCCGGCCGTGGCCGGAAGCCAGGGCGGCATCACCTCGCTGGCGCCGCTGGTGGACGCG
GTGAAGGGCGCGGTGGTCAACGTGGAGGTGCGCGCACGGCCCCGCAGGTCAGCCGCCATGCAGCGCCTGCCACCCGGCAT
GGCGGAGCGCTTCGGCCTGCCGCCCGGGTTCGGCGGTGAAGGCAACGGCCCGGCGCGACAGGGCGCGGGCTCCGGCTTCA
TCATCGACGCCTCGGGCATCGTCCTCACCAACAACCACGTGGTGGAGGACGCCGACCAGGTGCGCGTGAAGCTGGATGAC
GGACGTGCCTTCGACGCGGAGGTGATGGGCCGCGACCCGCTCACCGACGTGGCCCTGCTGAAGCTGAAGGGGGCGCCGGG
CAACCTGCCGGCGGTGCCGCTGGGGGACTCGGACGCGCTGCGCGTGGGCGACGCCGTCATGGCCATTGGCAATCCCTTCG
GCCTGGCGTCCAGCGTGAGCGCGGGCATCCTCTCCGCGCGGGCCCGCGACATCCAGGCGGGCCCCTATGACGAATTCCTC
CAGACGGACGCCGCCATCAACCCCGGCAACTCCGGCGGGCCGCTCTTCAACATGCAGGGCGAGGTGGTGGGCATGAACAC
CGCCATCGTCGGCGGCGCCACGGGCATCGGCTTCGCGGTGCCCAGCAAGCTCATCCAGGCGCTGCTGCCGCAGCTCAAGG
AGACGGGCGTGGTGCGTCGCGGCTGGCTGGGCCTGGCCGTACAGGACCTCACGCCGGACCTGGCGCGGGCGCTGGGCCTG
GAAGCGATGAAGGGCGCGGTGGTGGCGGGCGTCAACCGCGGCAGCCCGGGTGAGCGCGCCGGCCTGCGCGAGGAGGACGT
CATCACCTCCGTCAACGGCAAGCCGGTGGAGTCCGCGGGCGGACTGACGCGCGCCGTGGCCCTGCTCCAGCCCGACAGCC
GCGTGAAGGTGAACCTGCTGCGCGGTGGCAAGGCGCAGTCGCTGGACGTCACCCTGGGCACGCGGCCCGCGCAGAATGGC
GAGCAAGAGGTACTTCCGCGCAACGCTTCCGCTTCCGCGCCGAGGCGGCTGGGCGTGCAACTGTCGGACGCGCGGGACGG
CGGCGCGCAGGTAGTCGCCGTGGAGCCGGGCAGCCCCGCCGAGCGCGGGGGACTGGTGCCAGGCATGGTGCTGGTCCAGG
TGGGCGACCAGAAAATCGCCAGCGTGTCGGACGCCGCCCAGGCGCTGACGGCCGCGAAGCCCGGCGCCGCACTGCTCCTG
CGCGTGCGCATGCCGGGGTCGGAGTCCACGCTGCTGCGCGCGGTGGAAGTCCCGGAGCGCTGA

Upstream 100 bases:

>100_bases
CGGCCGCAGGGCATCACCTTCCACCCCTCCAAGGTGGGACCTTTCTCGCGCAGGCCCCTCGCCTGGACCGGCATTTTCCC
TCTCGATTGGAGAACGAACG

Downstream 100 bases:

>100_bases
ACACGGTGGTGGGAAACTGTGGACCCCCGGGATGGTACGTAGACGACCCCGGGGGTTCTGAAACCGGAGGACACCTGACG
TAGAGTCCCCTCCGTGCCGC

Product: protease DO family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MACSLPSRRFLSALVLLPAATLGACGQAIGTASAASPAPTAQVAAAVPAQAAPPIQKALFNPAVAGSQGGITSLAPLVDA
VKGAVVNVEVRARPRRSAAMQRLPPGMAERFGLPPGFGGEGNGPARQGAGSGFIIDASGIVLTNNHVVEDADQVRVKLDD
GRAFDAEVMGRDPLTDVALLKLKGAPGNLPAVPLGDSDALRVGDAVMAIGNPFGLASSVSAGILSARARDIQAGPYDEFL
QTDAAINPGNSGGPLFNMQGEVVGMNTAIVGGATGIGFAVPSKLIQALLPQLKETGVVRRGWLGLAVQDLTPDLARALGL
EAMKGAVVAGVNRGSPGERAGLREEDVITSVNGKPVESAGGLTRAVALLQPDSRVKVNLLRGGKAQSLDVTLGTRPAQNG
EQEVLPRNASASAPRRLGVQLSDARDGGAQVVAVEPGSPAERGGLVPGMVLVQVGDQKIASVSDAAQALTAAKPGAALLL
RVRMPGSESTLLRAVEVPER

Sequences:

>Translated_500_residues
MACSLPSRRFLSALVLLPAATLGACGQAIGTASAASPAPTAQVAAAVPAQAAPPIQKALFNPAVAGSQGGITSLAPLVDA
VKGAVVNVEVRARPRRSAAMQRLPPGMAERFGLPPGFGGEGNGPARQGAGSGFIIDASGIVLTNNHVVEDADQVRVKLDD
GRAFDAEVMGRDPLTDVALLKLKGAPGNLPAVPLGDSDALRVGDAVMAIGNPFGLASSVSAGILSARARDIQAGPYDEFL
QTDAAINPGNSGGPLFNMQGEVVGMNTAIVGGATGIGFAVPSKLIQALLPQLKETGVVRRGWLGLAVQDLTPDLARALGL
EAMKGAVVAGVNRGSPGERAGLREEDVITSVNGKPVESAGGLTRAVALLQPDSRVKVNLLRGGKAQSLDVTLGTRPAQNG
EQEVLPRNASASAPRRLGVQLSDARDGGAQVVAVEPGSPAERGGLVPGMVLVQVGDQKIASVSDAAQALTAAKPGAALLL
RVRMPGSESTLLRAVEVPER
>Mature_499_residues
ACSLPSRRFLSALVLLPAATLGACGQAIGTASAASPAPTAQVAAAVPAQAAPPIQKALFNPAVAGSQGGITSLAPLVDAV
KGAVVNVEVRARPRRSAAMQRLPPGMAERFGLPPGFGGEGNGPARQGAGSGFIIDASGIVLTNNHVVEDADQVRVKLDDG
RAFDAEVMGRDPLTDVALLKLKGAPGNLPAVPLGDSDALRVGDAVMAIGNPFGLASSVSAGILSARARDIQAGPYDEFLQ
TDAAINPGNSGGPLFNMQGEVVGMNTAIVGGATGIGFAVPSKLIQALLPQLKETGVVRRGWLGLAVQDLTPDLARALGLE
AMKGAVVAGVNRGSPGERAGLREEDVITSVNGKPVESAGGLTRAVALLQPDSRVKVNLLRGGKAQSLDVTLGTRPAQNGE
QEVLPRNASASAPRRLGVQLSDARDGGAQVVAVEPGSPAERGGLVPGMVLVQVGDQKIASVSDAAQALTAAKPGAALLLR
VRMPGSESTLLRAVEVPER

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=253, Percent_Identity=37.9446640316205, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI22129776, Length=261, Percent_Identity=36.0153256704981, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI24308541, Length=269, Percent_Identity=35.6877323420074, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI7019477, Length=278, Percent_Identity=37.410071942446, Blast_Score=145, Evalue=1e-34,
Organism=Escherichia coli, GI1789629, Length=497, Percent_Identity=38.0281690140845, Blast_Score=268, Evalue=7e-73,
Organism=Escherichia coli, GI1786356, Length=445, Percent_Identity=38.2022471910112, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI1789630, Length=278, Percent_Identity=41.0071942446043, Blast_Score=192, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24646839, Length=303, Percent_Identity=33.993399339934, Blast_Score=152, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 50499; Mature: 50368

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACSLPSRRFLSALVLLPAATLGACGQAIGTASAASPAPTAQVAAAVPAQAAPPIQKALF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHC
NPAVAGSQGGITSLAPLVDAVKGAVVNVEVRARPRRSAAMQRLPPGMAERFGLPPGFGGE
CCCCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHCCCCHHHHCCCCCCCCCC
GNGPARQGAGSGFIIDASGIVLTNNHVVEDADQVRVKLDDGRAFDAEVMGRDPLTDVALL
CCCCCCCCCCCEEEEECCCEEEECCCEECCCCEEEEEECCCCEECHHHCCCCCCCCEEEE
KLKGAPGNLPAVPLGDSDALRVGDAVMAIGNPFGLASSVSAGILSARARDIQAGPYDEFL
EEECCCCCCCEEECCCCCCHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
QTDAAINPGNSGGPLFNMQGEVVGMNTAIVGGATGIGFAVPSKLIQALLPQLKETGVVRR
HCCCCCCCCCCCCCEEECCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
GWLGLAVQDLTPDLARALGLEAMKGAVVAGVNRGSPGERAGLREEDVITSVNGKPVESAG
CCCEEEHHHCCHHHHHHHCHHHHCCEEEEECCCCCCCCCCCCCHHHEEECCCCCCCHHCC
GLTRAVALLQPDSRVKVNLLRGGKAQSLDVTLGTRPAQNGEQEVLPRNASASAPRRLGVQ
CHHHEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCHHHCCE
LSDARDGGAQVVAVEPGSPAERGGLVPGMVLVQVGDQKIASVSDAAQALTAAKPGAALLL
EECCCCCCCEEEEECCCCCHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEE
RVRMPGSESTLLRAVEVPER
EEECCCCCCCEEEEECCCCC
>Mature Secondary Structure 
ACSLPSRRFLSALVLLPAATLGACGQAIGTASAASPAPTAQVAAAVPAQAAPPIQKALF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHC
NPAVAGSQGGITSLAPLVDAVKGAVVNVEVRARPRRSAAMQRLPPGMAERFGLPPGFGGE
CCCCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHCCCCHHHHCCCCCCCCCC
GNGPARQGAGSGFIIDASGIVLTNNHVVEDADQVRVKLDDGRAFDAEVMGRDPLTDVALL
CCCCCCCCCCCEEEEECCCEEEECCCEECCCCEEEEEECCCCEECHHHCCCCCCCCEEEE
KLKGAPGNLPAVPLGDSDALRVGDAVMAIGNPFGLASSVSAGILSARARDIQAGPYDEFL
EEECCCCCCCEEECCCCCCHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
QTDAAINPGNSGGPLFNMQGEVVGMNTAIVGGATGIGFAVPSKLIQALLPQLKETGVVRR
HCCCCCCCCCCCCCEEECCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
GWLGLAVQDLTPDLARALGLEAMKGAVVAGVNRGSPGERAGLREEDVITSVNGKPVESAG
CCCEEEHHHCCHHHHHHHCHHHHCCEEEEECCCCCCCCCCCCCHHHEEECCCCCCCHHCC
GLTRAVALLQPDSRVKVNLLRGGKAQSLDVTLGTRPAQNGEQEVLPRNASASAPRRLGVQ
CHHHEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCHHHCCE
LSDARDGGAQVVAVEPGSPAERGGLVPGMVLVQVGDQKIASVSDAAQALTAAKPGAALLL
EECCCCCCCEEEEECCCCCHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEE
RVRMPGSESTLLRAVEVPER
EEECCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]