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The map label for this gene is yycF [H]

Identifier: 108761671

GI number: 108761671

Start: 1583035

End: 1583733

Strand: Reverse

Name: yycF [H]

Synonym: MXAN_1349

Alternate gene names: 108761671

Gene position: 1583733-1583035 (Counterclockwise)

Preceding gene: 108760501

Following gene: 108758484

Centisome position: 17.33

GC content: 69.67

Gene sequence:

>699_bases
ATGAGCGACAAGACGCGGAGCATCCTGGTCGTGGAGGACGACCTGTCCATCCTCACGGGCCTGTCCATGAACCTGCGCTT
CGAGGGCTACGAGGTGCTCCAGGCCCAGGATGGCCGCACCGGCCTGGCGCGCGCGCTGGACGAGTCGCCAGACCTGGTGG
TGCTGGACGTCATGCTGCCGGAGCTCAATGGCTTCGAGGTCCTCAAGGAGCTGCGCCAGCGCGGCCGGGACACGCCCGTC
GTCGTGCTCTCCGCCAAGGGCATGGAGACGGACAAGATTGTCGGCCTCAACCTGGGCGCGGACGACTACGTGGTGAAGCC
GTTCGGCCTCCAGGAGCTGCTGGCCCGAATCAAGGCCGTGCTGCGCCGGCGCTACCCCTCCGCGGGGGCGGGTTCGCCGC
CGCCGGTGACCTTCGGCGACGTGAGCGTGGACATGGCCGCCCGCACGGTGGCACGCGCGAGGACGCCGGTGGAGCTCACC
GCGCAGGAGTTCAAGCTGCTGGCGCACTTCCTCGCGCACCCTGGACGCACCTTCACCCGCGAGGAGCTGCTGTCCGGCGC
GTGGGGCTACCACTACGAAGGCAGCGCCCGCACCGTGGACAACTTCATGCGCCAGCTGCGCCTGAAGTTCGAGCCCGACC
CGGAAGCCCCCCGCCACTTCCTCACCGTGCGCGGACTGGGCTACCGCTTCGAGCGCTGA

Upstream 100 bases:

>100_bases
TTACCCGGCGCATCATCGAAACCCACGGAGGCCGCATCTCCGTGCAGAGCGAGCCAGGCAAGGGAAGCCGGTTCACCATC
CACCTGCCGGCGGGGAAGGC

Downstream 100 bases:

>100_bases
CGGGCGCTCACGTTCCGGCGATGCCGATGTGGCGCGAGTCCTCCAGGTCGAAGGGCTTGCCGTCGAAGCGGCCGTAGCGC
TCGCGCGGCACCAACCCCGC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSDKTRSILVVEDDLSILTGLSMNLRFEGYEVLQAQDGRTGLARALDESPDLVVLDVMLPELNGFEVLKELRQRGRDTPV
VVLSAKGMETDKIVGLNLGADDYVVKPFGLQELLARIKAVLRRRYPSAGAGSPPPVTFGDVSVDMAARTVARARTPVELT
AQEFKLLAHFLAHPGRTFTREELLSGAWGYHYEGSARTVDNFMRQLRLKFEPDPEAPRHFLTVRGLGYRFER

Sequences:

>Translated_232_residues
MSDKTRSILVVEDDLSILTGLSMNLRFEGYEVLQAQDGRTGLARALDESPDLVVLDVMLPELNGFEVLKELRQRGRDTPV
VVLSAKGMETDKIVGLNLGADDYVVKPFGLQELLARIKAVLRRRYPSAGAGSPPPVTFGDVSVDMAARTVARARTPVELT
AQEFKLLAHFLAHPGRTFTREELLSGAWGYHYEGSARTVDNFMRQLRLKFEPDPEAPRHFLTVRGLGYRFER
>Mature_231_residues
SDKTRSILVVEDDLSILTGLSMNLRFEGYEVLQAQDGRTGLARALDESPDLVVLDVMLPELNGFEVLKELRQRGRDTPVV
VLSAKGMETDKIVGLNLGADDYVVKPFGLQELLARIKAVLRRRYPSAGAGSPPPVTFGDVSVDMAARTVARARTPVELTA
QEFKLLAHFLAHPGRTFTREELLSGAWGYHYEGSARTVDNFMRQLRLKFEPDPEAPRHFLTVRGLGYRFER

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=43.3035714285714, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=40.9691629955947, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=37.8854625550661, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.5291479820628, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=34.3347639484979, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=33.7552742616034, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.1351351351351, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=33.7837837837838, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=35.5555555555556, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=28.8888888888889, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.0396475770925, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=29.1845493562232, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=38.6792452830189, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790437, Length=133, Percent_Identity=33.8345864661654, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787487, Length=123, Percent_Identity=34.1463414634146, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25914; Mature: 25783

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKTRSILVVEDDLSILTGLSMNLRFEGYEVLQAQDGRTGLARALDESPDLVVLDVMLP
CCCCCCEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHCCCCCEEEEEEECC
ELNGFEVLKELRQRGRDTPVVVLSAKGMETDKIVGLNLGADDYVVKPFGLQELLARIKAV
CCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHH
LRRRYPSAGAGSPPPVTFGDVSVDMAARTVARARTPVELTAQEFKLLAHFLAHPGRTFTR
HHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
EELLSGAWGYHYEGSARTVDNFMRQLRLKFEPDPEAPRHFLTVRGLGYRFER
HHHHCCCCCEEECCCCHHHHHHHHHHEECCCCCCCCCCEEEEEECCCEECCC
>Mature Secondary Structure 
SDKTRSILVVEDDLSILTGLSMNLRFEGYEVLQAQDGRTGLARALDESPDLVVLDVMLP
CCCCCEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHCCCCCEEEEEEECC
ELNGFEVLKELRQRGRDTPVVVLSAKGMETDKIVGLNLGADDYVVKPFGLQELLARIKAV
CCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHH
LRRRYPSAGAGSPPPVTFGDVSVDMAARTVARARTPVELTAQEFKLLAHFLAHPGRTFTR
HHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
EELLSGAWGYHYEGSARTVDNFMRQLRLKFEPDPEAPRHFLTVRGLGYRFER
HHHHCCCCCEEECCCCHHHHHHHHHHEECCCCCCCCCCEEEEEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]