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The map label for this gene is proA [H]

Identifier: 108761630

GI number: 108761630

Start: 917355

End: 918845

Strand: Direct

Name: proA [H]

Synonym: MXAN_0805

Alternate gene names: 108761630

Gene position: 917355-918845 (Clockwise)

Preceding gene: 108762483

Following gene: 108760867

Centisome position: 10.04

GC content: 67.2

Gene sequence:

>1491_bases
ATGTCCATGTCACAGTCCAAGTTCGTCGGCGCCCTCACGGGCCTGGCGCTGCTCGCCGGTTGCGGCGGTAGCGATGGCAC
CACCCCCGCCTCCGAGGAGACGCTCGGTCAGGGGATGTCGTGGGAGGAGTTCCTCTCTCTCGTGTACCAGGAGCCCGACA
CGGGCATCTTCATCGCTGACGGTGACACGACGTTCGCGACCGAGAAGCACCTGCGCGAGTTCTATGACAACAACGTCAAG
AACGGGCAGCTCATCGTCCACCGCGTGGGCGGGGCGGACGCGAAGTGGAACGACACGCAGAAGCTGAACCTCACCTACTG
TGTGAGCACCACCTTCGGTAGCAACTACCAGGCGGTGGTCAACGCCATGGCCAGCGCGACGGGCGCGTGGGAGGCCGCCG
GCCACGTGAAGTTCGTCCACGTGAGCGCGCAGGACTCCAACTGCACCGCCTCCAACAACAACGTGCTGTTCGACGTGCGC
CCCATCAACGTGAATGGCCAGTACATCGCCCGCGCGTTCTTCCCGGGTGACGCGCGCTCCAGCCGCAACGTCCTCTTCGA
CAACAGCGCCTTCGGCCCCATGGGCGTCTGGACGCTGGCGGGCGTGACGCGCCACGAGCTGGGCCACGTGCTTGGCTTCC
GTCACGAGCACACCCGTCCCGAGGCCGGCGGCCAGTGCTTCGAGGACAGCAACTGGGGCGTGCTGACGACCTACGACAGC
GCGTCCGTCATGCACTACCCGCACTGCAACGGCACGCAGACGGGTGACCTCGTGCTGACCACGAAGGACGTCCAGGGCAT
CCAGGCGCTCTATGGCACGCCGAACGGTGAGCCGCCCCCGCCGCCCCCGCCGCCCCCGGAAGGTGTGCCCACCACGGAGA
CCCGCACGGGCTCTGTCGGCGCGAACGCGAACGTCAACTACGGTCCCTTCACCGTCGTTCCCCGCTCGACCTTCAAGGTC
GTGATGACGGGGACGGGCTCGGGTGACCCGGACCTCTACGTCCGCTTTGGCGCGGCTCCCACCACGACCGCGTACACCTG
CCGTCCGTACCTCGCCGGCGCCAACGAGACCTGCGAGCTCGAGGTCCCGGAAGGCGAGACCAGCGCGTACATCATGGTGC
GTGGCTACTCGGCCGCCAGCTTCAGCCTGACCATCAACTACCTCGCGCCCCTGGGCGGTGGTAGCGGCACGCCCACGAGC
GAGACGCGCTCTGGTTCCGTGACCTCGGGTGGCAGCCAGAACTACGGCCCCTTCAGCGTGAAGGCCGGCACCAACTTCAA
GGTCGTGATGACGGGCTCGGGTGACCCGGACCTCTACGTCCGCTTTGGCGCGGCCCCCACCACGAGCGCGTACAACTGCC
GTCCGTACCTCGCCGGCGCTTCCGAGACGTGCGACATCGCCGTGCCCGCGGGCCAGACCACCGCGTACATCATGGTGCGT
GGCTACTCGTCCGGTACGTTCAACCTGGCCATCAACTACACCAAGCCGTAG

Upstream 100 bases:

>100_bases
CGTTGAGCGGGGAGCCATCAGAAATCCTGAATGACGGCGATGGCTTGGATGCTGGCATGGCGGCTGCTTAATCGGCTGCG
AACCACTCATCCCAACAAGG

Downstream 100 bases:

>100_bases
TCCAGGCTTCGACGTGAAGTGAACGACGGGCGGTCTTCCTTCACGGGAAGGCCGCCCGTTTCTTTTTCCGCATGTCGCTG
GAGTCCGACGCGGCGGGCTG

Product: peptidase, M10A/M12A subfamilies

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSMSQSKFVGALTGLALLAGCGGSDGTTPASEETLGQGMSWEEFLSLVYQEPDTGIFIADGDTTFATEKHLREFYDNNVK
NGQLIVHRVGGADAKWNDTQKLNLTYCVSTTFGSNYQAVVNAMASATGAWEAAGHVKFVHVSAQDSNCTASNNNVLFDVR
PINVNGQYIARAFFPGDARSSRNVLFDNSAFGPMGVWTLAGVTRHELGHVLGFRHEHTRPEAGGQCFEDSNWGVLTTYDS
ASVMHYPHCNGTQTGDLVLTTKDVQGIQALYGTPNGEPPPPPPPPPEGVPTTETRTGSVGANANVNYGPFTVVPRSTFKV
VMTGTGSGDPDLYVRFGAAPTTTAYTCRPYLAGANETCELEVPEGETSAYIMVRGYSAASFSLTINYLAPLGGGSGTPTS
ETRSGSVTSGGSQNYGPFSVKAGTNFKVVMTGSGDPDLYVRFGAAPTTSAYNCRPYLAGASETCDIAVPAGQTTAYIMVR
GYSSGTFNLAINYTKP

Sequences:

>Translated_496_residues
MSMSQSKFVGALTGLALLAGCGGSDGTTPASEETLGQGMSWEEFLSLVYQEPDTGIFIADGDTTFATEKHLREFYDNNVK
NGQLIVHRVGGADAKWNDTQKLNLTYCVSTTFGSNYQAVVNAMASATGAWEAAGHVKFVHVSAQDSNCTASNNNVLFDVR
PINVNGQYIARAFFPGDARSSRNVLFDNSAFGPMGVWTLAGVTRHELGHVLGFRHEHTRPEAGGQCFEDSNWGVLTTYDS
ASVMHYPHCNGTQTGDLVLTTKDVQGIQALYGTPNGEPPPPPPPPPEGVPTTETRTGSVGANANVNYGPFTVVPRSTFKV
VMTGTGSGDPDLYVRFGAAPTTTAYTCRPYLAGANETCELEVPEGETSAYIMVRGYSAASFSLTINYLAPLGGGSGTPTS
ETRSGSVTSGGSQNYGPFSVKAGTNFKVVMTGSGDPDLYVRFGAAPTTSAYNCRPYLAGASETCDIAVPAGQTTAYIMVR
GYSSGTFNLAINYTKP
>Mature_495_residues
SMSQSKFVGALTGLALLAGCGGSDGTTPASEETLGQGMSWEEFLSLVYQEPDTGIFIADGDTTFATEKHLREFYDNNVKN
GQLIVHRVGGADAKWNDTQKLNLTYCVSTTFGSNYQAVVNAMASATGAWEAAGHVKFVHVSAQDSNCTASNNNVLFDVRP
INVNGQYIARAFFPGDARSSRNVLFDNSAFGPMGVWTLAGVTRHELGHVLGFRHEHTRPEAGGQCFEDSNWGVLTTYDSA
SVMHYPHCNGTQTGDLVLTTKDVQGIQALYGTPNGEPPPPPPPPPEGVPTTETRTGSVGANANVNYGPFTVVPRSTFKVV
MTGTGSGDPDLYVRFGAAPTTTAYTCRPYLAGANETCELEVPEGETSAYIMVRGYSAASFSLTINYLAPLGGGSGTPTSE
TRSGSVTSGGSQNYGPFSVKAGTNFKVVMTGSGDPDLYVRFGAAPTTSAYNCRPYLAGASETCDIAVPAGQTTAYIMVRG
YSSGTFNLAINYTKP

Specific function: Unknown

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 52386; Mature: 52255

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSQSKFVGALTGLALLAGCGGSDGTTPASEETLGQGMSWEEFLSLVYQEPDTGIFIAD
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCEEEEEC
GDTTFATEKHLREFYDNNVKNGQLIVHRVGGADAKWNDTQKLNLTYCVSTTFGSNYQAVV
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCHHHHH
NAMASATGAWEAAGHVKFVHVSAQDSNCTASNNNVLFDVRPINVNGQYIARAFFPGDARS
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCC
SRNVLFDNSAFGPMGVWTLAGVTRHELGHVLGFRHEHTRPEAGGQCFEDSNWGVLTTYDS
CCCEEEECCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEEECC
ASVMHYPHCNGTQTGDLVLTTKDVQGIQALYGTPNGEPPPPPPPPPEGVPTTETRTGSVG
CCEEECCCCCCCCCCCEEEEECCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANANVNYGPFTVVPRSTFKVVMTGTGSGDPDLYVRFGAAPTTTAYTCRPYLAGANETCEL
CCCCCCCCCEEEEECCEEEEEEEECCCCCCCEEEEECCCCCCCEEEECCEECCCCCEEEE
EVPEGETSAYIMVRGYSAASFSLTINYLAPLGGGSGTPTSETRSGSVTSGGSQNYGPFSV
ECCCCCCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KAGTNFKVVMTGSGDPDLYVRFGAAPTTSAYNCRPYLAGASETCDIAVPAGQTTAYIMVR
ECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCEEECCCCCCEEEEECCCCCEEEEEEE
GYSSGTFNLAINYTKP
ECCCCEEEEEEEECCC
>Mature Secondary Structure 
SMSQSKFVGALTGLALLAGCGGSDGTTPASEETLGQGMSWEEFLSLVYQEPDTGIFIAD
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCEEEEEC
GDTTFATEKHLREFYDNNVKNGQLIVHRVGGADAKWNDTQKLNLTYCVSTTFGSNYQAVV
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCHHHHH
NAMASATGAWEAAGHVKFVHVSAQDSNCTASNNNVLFDVRPINVNGQYIARAFFPGDARS
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCC
SRNVLFDNSAFGPMGVWTLAGVTRHELGHVLGFRHEHTRPEAGGQCFEDSNWGVLTTYDS
CCCEEEECCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEEECC
ASVMHYPHCNGTQTGDLVLTTKDVQGIQALYGTPNGEPPPPPPPPPEGVPTTETRTGSVG
CCEEECCCCCCCCCCCEEEEECCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANANVNYGPFTVVPRSTFKVVMTGTGSGDPDLYVRFGAAPTTTAYTCRPYLAGANETCEL
CCCCCCCCCEEEEECCEEEEEEEECCCCCCCEEEEECCCCCCCEEEECCEECCCCCEEEE
EVPEGETSAYIMVRGYSAASFSLTINYLAPLGGGSGTPTSETRSGSVTSGGSQNYGPFSV
ECCCCCCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KAGTNFKVVMTGSGDPDLYVRFGAAPTTSAYNCRPYLAGASETCDIAVPAGQTTAYIMVR
ECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCEEECCCCCCEEEEECCCCCEEEEEEE
GYSSGTFNLAINYTKP
ECCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2546861 [H]