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The map label for this gene is helD [H]

Identifier: 108761595

GI number: 108761595

Start: 6821731

End: 6823851

Strand: Direct

Name: helD [H]

Synonym: MXAN_5482

Alternate gene names: 108761595

Gene position: 6821731-6823851 (Clockwise)

Preceding gene: 108758694

Following gene: 108758011

Centisome position: 74.64

GC content: 71.62

Gene sequence:

>2121_bases
ATGAGCCACGTCGAGGCGTCGCTGCCGGACCATGCCCGCGCCATCATCGCCGAGGAAGAGGCCTTGCTGGCCCGTGTTCA
GTCCACGCTGGAAGCCGCGCGGCGCAAGTCCGCACGCGGACAGGACGCCCAGGGACTTGTCGCCCAGTTGCAGGTGCTGC
GGGACGACGCCTCCACCGCGGCCGTGGCCGACCTGCCGCACATCTTCGCGCAGATGAACCAGATGCGCTCCCTCCTGGAA
CGTCAGGAGGGAGTGAAGCTTCCCGACCCACAGGCCCCCTACTTCGCGCACCTGCGCCTCAATGGCGAAGGCGGCCCGCG
CGACTACCTGCTGGGCCGCACCACGTTCGCGGACGTGGGCGCCGGTGTGCGCGTCATCGACTGGCGCTTCGCCCCCGTGG
CCCGTGTCTTCTATTGCTACGAGGAAGGCGACGACTACGAGGAGTACTTCGGTGAGCGGCTCGCCGAGGGCAGCGTGGAG
ACGCGCCGGCTGGTCATCATCGAGCGCGGCGTGTTGACGCGCATCATCTCCGGCGCGCTGGTGCTGGAGCGCCTGGCGGA
CGGTACATGGCGCAGCGTGAGCCGCGACTTCGCCACGCTCCAGTCGGGCGGCGCGGGGACGGCGGCGCGGCCGGAGTTCC
TGGGCACCGGCAAGGGCGCGCGGCGCATCGAGGATGCCTTTGGCGTCACCGCCATGCTGGACGCCGAGCAGTACGAGGCC
CTCAGCACCGGCCCGGACCGGCCGCTGCTGGTGCTGGGCAGCGCGGGCAGTGGGAAGACGACCGTGGCGCTGCACCGGCT
GGCGAAGCTGGCCTTCGACGACCCGAGGACGTTCCCCCAGGCCCGCATGAAGCTCATCGTCCCGGAAGAAGGGCTGGCGC
GGCTGTCCCGCCGGCTGCTGGCGCCGCTGGGCCTGGGCAACGTGGCCGTGCAGACGCGGGATGCCTGGCTGCTCGCCACC
GCGCGCTCCGCCTTCAACGTGCCCGGCATCAAGCTGTGGAATGACACGCCGCCGCTGGTGTCCCGCCTCAAGCGCCACCC
CACCCTGCGGCGCGCGTTGGCCGCCCGGGTGGGCGTGCCAAAGACAGACGCGGGCACCACGCTGGAGCGGTTGCGCACGC
GGATGGCGGACGCATACATGGACCGGCGCTTCTTGGAGAGCGTGGTCACCGCCGCCAAGGGCGAGATTCCTCGCACCGCC
ATCGACGAGACGCTGGAGCACACGCGCCTCCAGCTCGCCACGCCGCTGTCCAAGGTGCTCAAGGACATCACCGACGCGGA
GCGGCTCATCACCGTGGATGGGCGCTCCATCGAGGACGACACGCCGGACGCCATGGCCGGCACCGTGGACCTGGACGACC
TGCCCGTCCTGATGTTCCTCAAGGCCCAGCACACCTCGCTGGGCCTGGAGCGGCTGGCGCACGTGGTGCTCGACGAGGCC
GAGGACTTCTCCCTCTTCGAGCTCTTCGCCGTCCGCCAACTGCTGGGCAAGGGCAAGAGCTGCACGCTGGCGGGCGACGA
GATGCAGCAGACGGACGCGGGCTTCGCGGGCTGGCCCGCCGTCCTCAACGAGCTCAACATCCGTGACGCCGCCACCTGCC
GGCTTCAGGTCTCCTACCGGTGCCCCCGGCCCGTGGTGGAGCTGGCGCGGCAGGTGCTGGGCGCGCAGGCCCCGGAGGCC
GCCGCCACCGGCCGCGCGGGCGCTCCGGTGGGCTTCCACCACTTCCCCGACGAGGCCCAGGCCCAGCTCTTCATCGGCGA
GGCGCTCCGGGACCTCGTCGCCCGCGAGCCCCACGCCTCCGTGGGCGTCATCGCCAGCAGCCCAGAGTCCGCGCAGGCCA
TCTACCGCGTCGTCGCCGACCAGCGCTGGGCGCGGCTGGTGAGCGACGGCGAGTTCACCTTCGAGCCCGGCGTGGACGTC
ACCGACGTGGGCAGCGTGAAGGGCCTGGAGTTCGACTACGTCATCCTCCCGGACGCGACGGCGCGGGCCTACCCGGTGGA
CGACGAGTCACGCCGCCGCCTGCACGTGGCGGTGACGCGCACCTCCCATCAGCTCTGGGTGGTGTCCTCCGGCGTCCGCT
CGCACCTGGTCACGCAGGGTGGCGCGGCAGCTCCACGATGA

Upstream 100 bases:

>100_bases
ATGTCCATCCCTTCCTGGTACAGAGTACCAAAAAGACAGCATTTCCTTCAGGAAAAACAACAGGTTGACGCATACGGCGC
CGAGGTTCACCTTGCCGCGC

Downstream 100 bases:

>100_bases
AGGTGGAGCCCTGGCCGGGCACGCTCTCCACGAGGATGCGACCCTCCATGGCGTCCACAATCTGCTTCACGATCCACAGG
CCCAGCCCCAGTCCGCCGTA

Product: putative helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MSHVEASLPDHARAIIAEEEALLARVQSTLEAARRKSARGQDAQGLVAQLQVLRDDASTAAVADLPHIFAQMNQMRSLLE
RQEGVKLPDPQAPYFAHLRLNGEGGPRDYLLGRTTFADVGAGVRVIDWRFAPVARVFYCYEEGDDYEEYFGERLAEGSVE
TRRLVIIERGVLTRIISGALVLERLADGTWRSVSRDFATLQSGGAGTAARPEFLGTGKGARRIEDAFGVTAMLDAEQYEA
LSTGPDRPLLVLGSAGSGKTTVALHRLAKLAFDDPRTFPQARMKLIVPEEGLARLSRRLLAPLGLGNVAVQTRDAWLLAT
ARSAFNVPGIKLWNDTPPLVSRLKRHPTLRRALAARVGVPKTDAGTTLERLRTRMADAYMDRRFLESVVTAAKGEIPRTA
IDETLEHTRLQLATPLSKVLKDITDAERLITVDGRSIEDDTPDAMAGTVDLDDLPVLMFLKAQHTSLGLERLAHVVLDEA
EDFSLFELFAVRQLLGKGKSCTLAGDEMQQTDAGFAGWPAVLNELNIRDAATCRLQVSYRCPRPVVELARQVLGAQAPEA
AATGRAGAPVGFHHFPDEAQAQLFIGEALRDLVAREPHASVGVIASSPESAQAIYRVVADQRWARLVSDGEFTFEPGVDV
TDVGSVKGLEFDYVILPDATARAYPVDDESRRRLHVAVTRTSHQLWVVSSGVRSHLVTQGGAAAPR

Sequences:

>Translated_706_residues
MSHVEASLPDHARAIIAEEEALLARVQSTLEAARRKSARGQDAQGLVAQLQVLRDDASTAAVADLPHIFAQMNQMRSLLE
RQEGVKLPDPQAPYFAHLRLNGEGGPRDYLLGRTTFADVGAGVRVIDWRFAPVARVFYCYEEGDDYEEYFGERLAEGSVE
TRRLVIIERGVLTRIISGALVLERLADGTWRSVSRDFATLQSGGAGTAARPEFLGTGKGARRIEDAFGVTAMLDAEQYEA
LSTGPDRPLLVLGSAGSGKTTVALHRLAKLAFDDPRTFPQARMKLIVPEEGLARLSRRLLAPLGLGNVAVQTRDAWLLAT
ARSAFNVPGIKLWNDTPPLVSRLKRHPTLRRALAARVGVPKTDAGTTLERLRTRMADAYMDRRFLESVVTAAKGEIPRTA
IDETLEHTRLQLATPLSKVLKDITDAERLITVDGRSIEDDTPDAMAGTVDLDDLPVLMFLKAQHTSLGLERLAHVVLDEA
EDFSLFELFAVRQLLGKGKSCTLAGDEMQQTDAGFAGWPAVLNELNIRDAATCRLQVSYRCPRPVVELARQVLGAQAPEA
AATGRAGAPVGFHHFPDEAQAQLFIGEALRDLVAREPHASVGVIASSPESAQAIYRVVADQRWARLVSDGEFTFEPGVDV
TDVGSVKGLEFDYVILPDATARAYPVDDESRRRLHVAVTRTSHQLWVVSSGVRSHLVTQGGAAAPR
>Mature_705_residues
SHVEASLPDHARAIIAEEEALLARVQSTLEAARRKSARGQDAQGLVAQLQVLRDDASTAAVADLPHIFAQMNQMRSLLER
QEGVKLPDPQAPYFAHLRLNGEGGPRDYLLGRTTFADVGAGVRVIDWRFAPVARVFYCYEEGDDYEEYFGERLAEGSVET
RRLVIIERGVLTRIISGALVLERLADGTWRSVSRDFATLQSGGAGTAARPEFLGTGKGARRIEDAFGVTAMLDAEQYEAL
STGPDRPLLVLGSAGSGKTTVALHRLAKLAFDDPRTFPQARMKLIVPEEGLARLSRRLLAPLGLGNVAVQTRDAWLLATA
RSAFNVPGIKLWNDTPPLVSRLKRHPTLRRALAARVGVPKTDAGTTLERLRTRMADAYMDRRFLESVVTAAKGEIPRTAI
DETLEHTRLQLATPLSKVLKDITDAERLITVDGRSIEDDTPDAMAGTVDLDDLPVLMFLKAQHTSLGLERLAHVVLDEAE
DFSLFELFAVRQLLGKGKSCTLAGDEMQQTDAGFAGWPAVLNELNIRDAATCRLQVSYRCPRPVVELARQVLGAQAPEAA
ATGRAGAPVGFHHFPDEAQAQLFIGEALRDLVAREPHASVGVIASSPESAQAIYRVVADQRWARLVSDGEFTFEPGVDVT
DVGSVKGLEFDYVILPDATARAYPVDDESRRRLHVAVTRTSHQLWVVSSGVRSHLVTQGGAAAPR

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76935; Mature: 76804

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVEASLPDHARAIIAEEEALLARVQSTLEAARRKSARGQDAQGLVAQLQVLRDDASTA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHH
AVADLPHIFAQMNQMRSLLERQEGVKLPDPQAPYFAHLRLNGEGGPRDYLLGRTTFADVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEECCCHHHHCC
AGVRVIDWRFAPVARVFYCYEEGDDYEEYFGERLAEGSVETRRLVIIERGVLTRIISGAL
CCEEEEEEECHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHH
VLERLADGTWRSVSRDFATLQSGGAGTAARPEFLGTGKGARRIEDAFGVTAMLDAEQYEA
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECHHHHHH
LSTGPDRPLLVLGSAGSGKTTVALHRLAKLAFDDPRTFPQARMKLIVPEEGLARLSRRLL
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHCEEEECCCHHHHHHHHHHH
APLGLGNVAVQTRDAWLLATARSAFNVPGIKLWNDTPPLVSRLKRHPTLRRALAARVGVP
CCCCCCCEEEEECCEEEEEEHHHHCCCCCEEECCCCCHHHHHHHHCHHHHHHHHHHCCCC
KTDAGTTLERLRTRMADAYMDRRFLESVVTAAKGEIPRTAIDETLEHTRLQLATPLSKVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KDITDAERLITVDGRSIEDDTPDAMAGTVDLDDLPVLMFLKAQHTSLGLERLAHVVLDEA
HHHCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCC
EDFSLFELFAVRQLLGKGKSCTLAGDEMQQTDAGFAGWPAVLNELNIRDAATCRLQVSYR
CCCHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECC
CPRPVVELARQVLGAQAPEAAATGRAGAPVGFHHFPDEAQAQLFIGEALRDLVAREPHAS
CCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
VGVIASSPESAQAIYRVVADQRWARLVSDGEFTFEPGVDVTDVGSVKGLEFDYVILPDAT
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCC
ARAYPVDDESRRRLHVAVTRTSHQLWVVSSGVRSHLVTQGGAAAPR
CCCCCCCCCCCCEEEEEEEECCCEEEEEECCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SHVEASLPDHARAIIAEEEALLARVQSTLEAARRKSARGQDAQGLVAQLQVLRDDASTA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHH
AVADLPHIFAQMNQMRSLLERQEGVKLPDPQAPYFAHLRLNGEGGPRDYLLGRTTFADVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEECCCHHHHCC
AGVRVIDWRFAPVARVFYCYEEGDDYEEYFGERLAEGSVETRRLVIIERGVLTRIISGAL
CCEEEEEEECHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHH
VLERLADGTWRSVSRDFATLQSGGAGTAARPEFLGTGKGARRIEDAFGVTAMLDAEQYEA
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECHHHHHH
LSTGPDRPLLVLGSAGSGKTTVALHRLAKLAFDDPRTFPQARMKLIVPEEGLARLSRRLL
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHCEEEECCCHHHHHHHHHHH
APLGLGNVAVQTRDAWLLATARSAFNVPGIKLWNDTPPLVSRLKRHPTLRRALAARVGVP
CCCCCCCEEEEECCEEEEEEHHHHCCCCCEEECCCCCHHHHHHHHCHHHHHHHHHHCCCC
KTDAGTTLERLRTRMADAYMDRRFLESVVTAAKGEIPRTAIDETLEHTRLQLATPLSKVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KDITDAERLITVDGRSIEDDTPDAMAGTVDLDDLPVLMFLKAQHTSLGLERLAHVVLDEA
HHHCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCC
EDFSLFELFAVRQLLGKGKSCTLAGDEMQQTDAGFAGWPAVLNELNIRDAATCRLQVSYR
CCCHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECC
CPRPVVELARQVLGAQAPEAAATGRAGAPVGFHHFPDEAQAQLFIGEALRDLVAREPHAS
CCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
VGVIASSPESAQAIYRVVADQRWARLVSDGEFTFEPGVDVTDVGSVKGLEFDYVILPDAT
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCC
ARAYPVDDESRRRLHVAVTRTSHQLWVVSSGVRSHLVTQGGAAAPR
CCCCCCCCCCCCEEEEEEEECCCEEEEEECCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]