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The map label for this gene is recQ [H]

Identifier: 108761530

GI number: 108761530

Start: 2287969

End: 2290047

Strand: Reverse

Name: recQ [H]

Synonym: MXAN_1950

Alternate gene names: 108761530

Gene position: 2290047-2287969 (Counterclockwise)

Preceding gene: 108763555

Following gene: 108761475

Centisome position: 25.06

GC content: 70.32

Gene sequence:

>2079_bases
ATGCGCGCGATGCCGGTGGCCCTGCCCTACCTCGAGGAAGCACAGCAGGGGCTGGTCCGCCACTTCGGCCTGTCCCAGTT
CCGGCCGGGGCAGGACCAGGTCATCTCCTCCGTCTTGAGCGGCCGCAACACGGTGGTGGTGATGCCCACCGGCGCGGGCA
AGAGCCTGTGTTACCAGTTGCCCGCCACGCTGCTGCCGGGGCTGACACTGGTGGTGTCGCCGCTGATTGCCCTGATGAAG
GACCAGGTGGAGCAGCTCACCGCGCGCGGCATCCCGGCGACCTTCATCAACTCATCGCTGTCCGACCTGGAGCGCGCGGA
GCGGATGCGCAAGCTGCGCGCGCATGAGTACAAGCTGCTCTACGTGGCGCCCGAGCGCTTCCGCAGCCAGAGCTTCCTGG
AGACGGTGTCCGCGCTGGGCGTGGACCTGCTCGCCGTGGACGAAGCGCACTGCATCTCCCAGTGGGGGCACGACTTCAGG
CCGGACTACGCGCTGCTCGGACAGGTGCGAAAGCGGCTGCGTCCGCCGCGCACGGTGGCGCTCACCGCCACGGCCACGCC
GGAGGTCCGCGCGGACATCGTGCGTGTGCTGCTGATGAAGGACCCGCAGGAATTCGCCATGGGCTTCGACCGCCCCAACC
TCTTCCTGGGCAAGCAGGAGGTGGGCGGCGACGCGGACCGGCACGAGGCCTGCGCACGACTGGCGTCCGCGGGCGGGAGC
GGCATCGTGTACTGCTCCACGCGGCGCGCGGCAGAGGGCATCTTCTCCGAACTGCATGGGCGCGGAGTGAAGGCGGTGCT
GTACCACGCGGGCATGGACGATGACGCCCGTCGCCGCGCCCAGGACACCTTCATGTCCGCGAAGGAAGCGGTGGCGGTGG
CCACCAACGCCTTCGGCATGGGCATCGACAAGCCGGACATCCGCTTCGTCGGCCACGCCAACATCCCGCGGGCGGTGGAG
GCGTACTACCAGGAGATTGGCCGCGCGGGCCGCGACGGACAGGCCGCGCGCGCGGTGCTCCTCTTCAACCACTCGGATGT
CTTCACCCAGGAGCGGCTCATCCAGAGCAGCCACCCGGCCGAGGCCATCTTCGGGGACGTGTGGAACGTGCTCCAGTCGG
TGGAGGAATTCGAGAGAGGCGTGCACGCGCTCGCGGGCACGGTGAACGCCAGCGAGTTCGAGGTCTCCGCGGCGCTGCGC
ATCCTCGAACGCGAGGGAAAGGTGGAGCGCGGTGGCCGAGGCGAGGGCGAGCACGGCATCACCCTGCTGGAGAAGGCCGC
CTCGGCGCAGCCGCACTCGCCGGACGCACAGCGGCTGCTCAAGTCCTTGCTGGAGACATTCCCCGTGGGCCGGCAGGTCA
CCACGGAGCTGCCCATCCTCGCGCGCCGCATCGGTCTGTCGGTGGACGAGGTCCGCCACGCGCTGGGCTTGTTGGAGAAG
GCCCACGTGGCCAAGGTACGGCGCCCCTTCGCCGGCCGCTCCATTCGCGCGCTGGAGCGGGTGCCCTTCCGCGAGCTGGG
GCTCGACCTGAGCCGCGTGCGGGAGCAGGAGCGGCAGAACCTGGCGCTGCTGCGCCGGATGACCGAGTACGCCTATACGG
ACCGGGACAAGAAGTGCCGGCGCTCGGCCATCCTCCGCTACTTCGGCCAACGCGACACCCACACGTCGTGCGGCAACTGC
GACGTGTGCGCGCCGGAGAAGATGCCCACGCTGCTGGCCCACGGGCCGGCCGCGTCTCGCGCCCGAGGCACGAGCTCCGC
GGCGGCGCCGGTGGTGACGAACTACAGCGAGCTGGCCTCCACGGAGCTACGGCGCTGGCGCAAGGAGCTGGCGAAGGACC
TGGGCGTTGCCCCCTTCATCATCTTCAACGACGCCACGCTGCTGGGCCTGTCCGCGGCGCTACCGGTGGACCGGGAGGGC
TTCCTCGCGGTGAAGGGCACCGGGGAGAGCCGCTGGGAGCGCTTTGGCCCCAAGGTGGTGGAAATCTGCCTGATGGCGCG
CGCCGCGGGCCACGAGCCCCAAGCCGTACCAGACGCCGCGGTGCGCGCGCGCAAGCCCACGATTCGTCGCCGGAGCTGA

Upstream 100 bases:

>100_bases
CGAACGCGGCTGGCTGTTCCGGTTCCACCAGGGCTCGACCTGTGAGTGGAGGCCGCGCGGCGGCCTCGTTTCCGTTGACG
GCTGGACCAGGATGATGAAC

Downstream 100 bases:

>100_bases
AGCCGCGGCCTCCTCAGGGGTGCCGACGTCCGCCCTCGCGCAGGGCCCGGCGCGCCAGCAGCGTTCGGACGCCGCCCATC
AACGTGCCCACCACCATCGC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MRAMPVALPYLEEAQQGLVRHFGLSQFRPGQDQVISSVLSGRNTVVVMPTGAGKSLCYQLPATLLPGLTLVVSPLIALMK
DQVEQLTARGIPATFINSSLSDLERAERMRKLRAHEYKLLYVAPERFRSQSFLETVSALGVDLLAVDEAHCISQWGHDFR
PDYALLGQVRKRLRPPRTVALTATATPEVRADIVRVLLMKDPQEFAMGFDRPNLFLGKQEVGGDADRHEACARLASAGGS
GIVYCSTRRAAEGIFSELHGRGVKAVLYHAGMDDDARRRAQDTFMSAKEAVAVATNAFGMGIDKPDIRFVGHANIPRAVE
AYYQEIGRAGRDGQAARAVLLFNHSDVFTQERLIQSSHPAEAIFGDVWNVLQSVEEFERGVHALAGTVNASEFEVSAALR
ILEREGKVERGGRGEGEHGITLLEKAASAQPHSPDAQRLLKSLLETFPVGRQVTTELPILARRIGLSVDEVRHALGLLEK
AHVAKVRRPFAGRSIRALERVPFRELGLDLSRVREQERQNLALLRRMTEYAYTDRDKKCRRSAILRYFGQRDTHTSCGNC
DVCAPEKMPTLLAHGPAASRARGTSSAAAPVVTNYSELASTELRRWRKELAKDLGVAPFIIFNDATLLGLSAALPVDREG
FLAVKGTGESRWERFGPKVVEICLMARAAGHEPQAVPDAAVRARKPTIRRRS

Sequences:

>Translated_692_residues
MRAMPVALPYLEEAQQGLVRHFGLSQFRPGQDQVISSVLSGRNTVVVMPTGAGKSLCYQLPATLLPGLTLVVSPLIALMK
DQVEQLTARGIPATFINSSLSDLERAERMRKLRAHEYKLLYVAPERFRSQSFLETVSALGVDLLAVDEAHCISQWGHDFR
PDYALLGQVRKRLRPPRTVALTATATPEVRADIVRVLLMKDPQEFAMGFDRPNLFLGKQEVGGDADRHEACARLASAGGS
GIVYCSTRRAAEGIFSELHGRGVKAVLYHAGMDDDARRRAQDTFMSAKEAVAVATNAFGMGIDKPDIRFVGHANIPRAVE
AYYQEIGRAGRDGQAARAVLLFNHSDVFTQERLIQSSHPAEAIFGDVWNVLQSVEEFERGVHALAGTVNASEFEVSAALR
ILEREGKVERGGRGEGEHGITLLEKAASAQPHSPDAQRLLKSLLETFPVGRQVTTELPILARRIGLSVDEVRHALGLLEK
AHVAKVRRPFAGRSIRALERVPFRELGLDLSRVREQERQNLALLRRMTEYAYTDRDKKCRRSAILRYFGQRDTHTSCGNC
DVCAPEKMPTLLAHGPAASRARGTSSAAAPVVTNYSELASTELRRWRKELAKDLGVAPFIIFNDATLLGLSAALPVDREG
FLAVKGTGESRWERFGPKVVEICLMARAAGHEPQAVPDAAVRARKPTIRRRS
>Mature_692_residues
MRAMPVALPYLEEAQQGLVRHFGLSQFRPGQDQVISSVLSGRNTVVVMPTGAGKSLCYQLPATLLPGLTLVVSPLIALMK
DQVEQLTARGIPATFINSSLSDLERAERMRKLRAHEYKLLYVAPERFRSQSFLETVSALGVDLLAVDEAHCISQWGHDFR
PDYALLGQVRKRLRPPRTVALTATATPEVRADIVRVLLMKDPQEFAMGFDRPNLFLGKQEVGGDADRHEACARLASAGGS
GIVYCSTRRAAEGIFSELHGRGVKAVLYHAGMDDDARRRAQDTFMSAKEAVAVATNAFGMGIDKPDIRFVGHANIPRAVE
AYYQEIGRAGRDGQAARAVLLFNHSDVFTQERLIQSSHPAEAIFGDVWNVLQSVEEFERGVHALAGTVNASEFEVSAALR
ILEREGKVERGGRGEGEHGITLLEKAASAQPHSPDAQRLLKSLLETFPVGRQVTTELPILARRIGLSVDEVRHALGLLEK
AHVAKVRRPFAGRSIRALERVPFRELGLDLSRVREQERQNLALLRRMTEYAYTDRDKKCRRSAILRYFGQRDTHTSCGNC
DVCAPEKMPTLLAHGPAASRARGTSSAAAPVVTNYSELASTELRRWRKELAKDLGVAPFIIFNDATLLGLSAALPVDREG
FLAVKGTGESRWERFGPKVVEICLMARAAGHEPQAVPDAAVRARKPTIRRRS

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=392, Percent_Identity=40.5612244897959, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI51242947, Length=348, Percent_Identity=45.4022988505747, Blast_Score=269, Evalue=5e-72,
Organism=Homo sapiens, GI51242943, Length=348, Percent_Identity=45.4022988505747, Blast_Score=269, Evalue=7e-72,
Organism=Homo sapiens, GI148612816, Length=348, Percent_Identity=45.4022988505747, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI14591902, Length=354, Percent_Identity=39.8305084745763, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI14591904, Length=354, Percent_Identity=39.8305084745763, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI110735439, Length=351, Percent_Identity=41.025641025641, Blast_Score=255, Evalue=9e-68,
Organism=Homo sapiens, GI169218196, Length=351, Percent_Identity=41.025641025641, Blast_Score=255, Evalue=1e-67,
Organism=Homo sapiens, GI284005309, Length=384, Percent_Identity=37.7604166666667, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI55749865, Length=362, Percent_Identity=22.9281767955801, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI222352149, Length=360, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI48994977, Length=334, Percent_Identity=50.2994011976048, Blast_Score=331, Evalue=8e-92,
Organism=Escherichia coli, GI87082221, Length=344, Percent_Identity=25, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787016, Length=374, Percent_Identity=25.4010695187166, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71987997, Length=359, Percent_Identity=42.0612813370474, Blast_Score=281, Evalue=6e-76,
Organism=Caenorhabditis elegans, GI71987993, Length=359, Percent_Identity=42.0612813370474, Blast_Score=281, Evalue=6e-76,
Organism=Caenorhabditis elegans, GI25145561, Length=385, Percent_Identity=41.2987012987013, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI32564293, Length=376, Percent_Identity=38.8297872340425, Blast_Score=261, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI17552866, Length=340, Percent_Identity=38.8235294117647, Blast_Score=234, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6323844, Length=360, Percent_Identity=39.4444444444444, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6324217, Length=340, Percent_Identity=24.4117647058824, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320224, Length=340, Percent_Identity=21.4705882352941, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646066, Length=353, Percent_Identity=43.9093484419263, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24664226, Length=366, Percent_Identity=39.0710382513661, Blast_Score=246, Evalue=4e-65,
Organism=Drosophila melanogaster, GI62472181, Length=368, Percent_Identity=38.8586956521739, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24664230, Length=368, Percent_Identity=38.8586956521739, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI21358123, Length=362, Percent_Identity=38.3977900552486, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21355075, Length=375, Percent_Identity=25.3333333333333, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76188; Mature: 76188

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50967 HRDC ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMPVALPYLEEAQQGLVRHFGLSQFRPGQDQVISSVLSGRNTVVVMPTGAGKSLCYQL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
PATLLPGLTLVVSPLIALMKDQVEQLTARGIPATFINSSLSDLERAERMRKLRAHEYKLL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEE
YVAPERFRSQSFLETVSALGVDLLAVDEAHCISQWGHDFRPDYALLGQVRKRLRPPRTVA
EECHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEE
LTATATPEVRADIVRVLLMKDPQEFAMGFDRPNLFLGKQEVGGDADRHEACARLASAGGS
EEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCHHCCCCCHHHHHHHHHHHCCCC
GIVYCSTRRAAEGIFSELHGRGVKAVLYHAGMDDDARRRAQDTFMSAKEAVAVATNAFGM
EEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIDKPDIRFVGHANIPRAVEAYYQEIGRAGRDGQAARAVLLFNHSDVFTQERLIQSSHPA
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCH
EAIFGDVWNVLQSVEEFERGVHALAGTVNASEFEVSAALRILEREGKVERGGRGEGEHGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
TLLEKAASAQPHSPDAQRLLKSLLETFPVGRQVTTELPILARRIGLSVDEVRHALGLLEK
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AHVAKVRRPFAGRSIRALERVPFRELGLDLSRVREQERQNLALLRRMTEYAYTDRDKKCR
HHHHHHHCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RSAILRYFGQRDTHTSCGNCDVCAPEKMPTLLAHGPAASRARGTSSAAAPVVTNYSELAS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHCCCCCCCCCCHHCCHHHHHH
TELRRWRKELAKDLGVAPFIIFNDATLLGLSAALPVDREGFLAVKGTGESRWERFGPKVV
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCHHHH
EICLMARAAGHEPQAVPDAAVRARKPTIRRRS
HHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRAMPVALPYLEEAQQGLVRHFGLSQFRPGQDQVISSVLSGRNTVVVMPTGAGKSLCYQL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
PATLLPGLTLVVSPLIALMKDQVEQLTARGIPATFINSSLSDLERAERMRKLRAHEYKLL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEE
YVAPERFRSQSFLETVSALGVDLLAVDEAHCISQWGHDFRPDYALLGQVRKRLRPPRTVA
EECHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEE
LTATATPEVRADIVRVLLMKDPQEFAMGFDRPNLFLGKQEVGGDADRHEACARLASAGGS
EEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCHHCCCCCHHHHHHHHHHHCCCC
GIVYCSTRRAAEGIFSELHGRGVKAVLYHAGMDDDARRRAQDTFMSAKEAVAVATNAFGM
EEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIDKPDIRFVGHANIPRAVEAYYQEIGRAGRDGQAARAVLLFNHSDVFTQERLIQSSHPA
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCH
EAIFGDVWNVLQSVEEFERGVHALAGTVNASEFEVSAALRILEREGKVERGGRGEGEHGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
TLLEKAASAQPHSPDAQRLLKSLLETFPVGRQVTTELPILARRIGLSVDEVRHALGLLEK
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AHVAKVRRPFAGRSIRALERVPFRELGLDLSRVREQERQNLALLRRMTEYAYTDRDKKCR
HHHHHHHCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RSAILRYFGQRDTHTSCGNCDVCAPEKMPTLLAHGPAASRARGTSSAAAPVVTNYSELAS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHCCCCCCCCCCHHCCHHHHHH
TELRRWRKELAKDLGVAPFIIFNDATLLGLSAALPVDREGFLAVKGTGESRWERFGPKVV
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCHHHH
EICLMARAAGHEPQAVPDAAVRARKPTIRRRS
HHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]