Click here to switch to the map view.

The map label for this gene is cfiA [H]

Identifier: 108761465

GI number: 108761465

Start: 1292634

End: 1293143

Strand: Reverse

Name: cfiA [H]

Synonym: MXAN_1110

Alternate gene names: 108761465

Gene position: 1293143-1292634 (Counterclockwise)

Preceding gene: 108762533

Following gene: 108761668

Centisome position: 14.15

GC content: 65.29

Gene sequence:

>510_bases
ATGCGTTACTTCACGAAGCAGCAGGGCCAGAAGGAAGCGGTCCCGGTGGACCTGGAGCCCCTGGGGAACGACCAGTTCAA
AATCACCGTGGGCGCCACCACGTACCAGGTGGACGCGCTGGCGCTGGAGCACGGCACGCTGTCCATGCTGGTAGACGGCC
AGTCGTACAACGTCGAGTTCGAGGAGAACGGCGACGAGCTTGGCGTGCTCCTGCGCGGCCAGGTGAACCGCATCGACGTG
GCGGATGAGCGCCGGCTCCGGCTGCGCGCGGCCAACGCGGCCTTCTCCGTCGAGGGCAAGCAGTTGGTCACCGCGCCCAT
GCCGGGCAAGGTGGTGAAGGTGCTGGTGAAGGTGGGCGACGAGGTGAAGGAGGGCCAGGGCCTCGTGGTGGTGGAAGCCA
TGAAGATGGAGAACGAGCTCAAGAGCCCCAAGGCGGGCAAGGTGACCGAGCTGTTCGCCAAGGAAGGCACCGCCGTGGAG
AACAACGCCAAGCTGGTGATGGTGGAATAG

Upstream 100 bases:

>100_bases
CCTGCTGCCAGTGGCGGCCAGGGCGGTGGCAACGGCGGCGTCTCCCCGTGGAAGCTGGCGCTGCGCGCGCGCCGCTAACC
CCCAGCTCGGAAGGACTCCC

Downstream 100 bases:

>100_bases
CTCCATGGAGATGCTCTGCACCCTGCGCAGCGCCACCGAGGCCCAGCGCGTTGCCCTGCTCCAGGCCCCCGAACAGTTGG
AGGACTTCGTCGACGATGAC

Product: biotin/lipoic acid binding domain-containing protein

Products: NA

Alternate protein names: 2-oxoglutarate carboxylase alpha subunit [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MRYFTKQQGQKEAVPVDLEPLGNDQFKITVGATTYQVDALALEHGTLSMLVDGQSYNVEFEENGDELGVLLRGQVNRIDV
ADERRLRLRAANAAFSVEGKQLVTAPMPGKVVKVLVKVGDEVKEGQGLVVVEAMKMENELKSPKAGKVTELFAKEGTAVE
NNAKLVMVE

Sequences:

>Translated_169_residues
MRYFTKQQGQKEAVPVDLEPLGNDQFKITVGATTYQVDALALEHGTLSMLVDGQSYNVEFEENGDELGVLLRGQVNRIDV
ADERRLRLRAANAAFSVEGKQLVTAPMPGKVVKVLVKVGDEVKEGQGLVVVEAMKMENELKSPKAGKVTELFAKEGTAVE
NNAKLVMVE
>Mature_169_residues
MRYFTKQQGQKEAVPVDLEPLGNDQFKITVGATTYQVDALALEHGTLSMLVDGQSYNVEFEENGDELGVLLRGQVNRIDV
ADERRLRLRAANAAFSVEGKQLVTAPMPGKVVKVLVKVGDEVKEGQGLVVVEAMKMENELKSPKAGKVTELFAKEGTAVE
NNAKLVMVE

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=65, Percent_Identity=49.2307692307692, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17567343, Length=162, Percent_Identity=32.7160493827161, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319695, Length=99, Percent_Identity=35.3535353535354, Blast_Score=61, Evalue=1e-10,
Organism=Drosophila melanogaster, GI281363050, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652224, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652222, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652220, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652218, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652212, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652210, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652214, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19921944, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652216, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.7 [H]

Molecular weight: Translated: 18460; Mature: 18460

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYFTKQQGQKEAVPVDLEPLGNDQFKITVGATTYQVDALALEHGTLSMLVDGQSYNVEF
CCCCCCCCCCCCCCCEECCCCCCCEEEEEECCEEEEEEEEEECCCEEEEEECCCEEEEEE
EENGDELGVLLRGQVNRIDVADERRLRLRAANAAFSVEGKQLVTAPMPGKVVKVLVKVGD
CCCCCEEEEEEECCCCEEECCCCCEEEEEECCCEEEECCCEEEECCCCHHHHHHHHHHCC
EVKEGQGLVVVEAMKMENELKSPKAGKVTELFAKEGTAVENNAKLVMVE
CHHCCCCEEEEEEEHHHHHHCCCCCCCHHHHHHCCCCEEECCEEEEEEC
>Mature Secondary Structure
MRYFTKQQGQKEAVPVDLEPLGNDQFKITVGATTYQVDALALEHGTLSMLVDGQSYNVEF
CCCCCCCCCCCCCCCEECCCCCCCEEEEEECCEEEEEEEEEECCCEEEEEECCCEEEEEE
EENGDELGVLLRGQVNRIDVADERRLRLRAANAAFSVEGKQLVTAPMPGKVVKVLVKVGD
CCCCCEEEEEEECCCCEEECCCCCEEEEEECCCEEEECCCEEEECCCCHHHHHHHHHHCC
EVKEGQGLVVVEAMKMENELKSPKAGKVTELFAKEGTAVENNAKLVMVE
CHHCCCCEEEEEEEHHHHHHCCCCCCCHHHHHHCCCCEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA