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The map label for this gene is gatA [H]

Identifier: 108761318

GI number: 108761318

Start: 6053772

End: 6055445

Strand: Reverse

Name: gatA [H]

Synonym: MXAN_4838

Alternate gene names: 108761318

Gene position: 6055445-6053772 (Counterclockwise)

Preceding gene: 108757780

Following gene: 108762121

Centisome position: 66.25

GC content: 70.13

Gene sequence:

>1674_bases
ATGACCTACCAACGCAATCCCGTGAAGGCGCCCCGTGTGTCGGGCCTGGCGCTCAAGGCTTTCGTGAACGCGCTCGAGAG
CGGCGTCGGGTCGGTGATGCTGGACAAGCTGACGCGGGACAGCGGCATCGAGCGATGGCGTGAGCTCCCGGCGGGGGACG
CGCCGCCGCTCCAGTTTCCGTTGGCCCAGGGAACTGCCGCCACGGAGTCGCAGACACCCACGGAGCAGGCCGCGCGCGCC
ATCGCCGCGTCCGCCAGTCCACCGGAGCGTGAGAGCGTTGCGGCCTATGTCCGCGCCTACCGCGAGGGCGCCACGGACCC
GGTGGCCGTGGTGAATCGAATTCATGAATCCATTGCCCGGATGGACAGTGGGAAGCAGCGCCTGGGCTTGTTCATCGCCC
GCAAGCCGGACGACGTGCACCGGGCCGCGGAGGCTTCCTCCGAGCGGCTGCGCGAGGGCCGTCCGCTGAGCGTGCTCGAC
GGGATTCCCGTCGTGCTGAAGGACGAGGTCGACCTGGCCGGGTTCCCCACCACGCTGGGCACGCGGTTTCGCACGCAGGT
GGCCGCCGCGGACTCGACGGTGGCGGCCCGGCTCAAGGCCGCGGGCGCCATCATCCTCGGCAAGGCCAACATGAATGAGA
TTGGCATCAACCCCATCGGGTTGAATCCCCATCACGGCGCCGCTCGCAACCCCTGGGACACGGGCCGCATCACCGGTGGC
AGTTCCAGTGCCTCCGCCGCCGCCGTGGCCGCCGGCCTGTGCCCCTTGAGCATCGGTGCCGACGGCGGCGGTTCCATCCG
CATCCCCGCGGCCCTTTGCGGCATCGTGGGCCTCAAGGCGACGTGGGGCCGCATCCCGGAGACGGGCGTACCGCCGCTGT
GCTGGAACGTGGGCCACGTGGGGCCCATGGGCCTCACCGTGGACGATGTCGCCGCGGCGTATGCGGTGCTCGCGGGGCCG
GATGGGCATGACCTCGTCTCGCAGGGGCAGTCACCGCATCACCTGTCTGGCTACGAGGATGAAGGCCTGAGCGGCGTGCG
GCTGGGCATCTGCTGGGACTACTTCGAGGACGCCGACGCGGACGTCGTCGCCCGCTGCAAGGAGGCCGTGGCCGCGCTGT
CGGCCGCGGGCGCGCGCGTGGTGGAGATTCCGCCTCCCGACCTCAACACCGTGCTGTGGACGCACAGTTGCATCATCCTG
AGCGAGATGTCGGAGGTGATGCTCCCCCACGTGAAGGCGCATCCGTCGGAGTTCGGGCTCGACACGCGCACCAACCTGGC
CATTGGCCGGCACTTCCGGGCCACGGACCTGGTGCATGCCCTGCGGCACCGGCACCGCCTGACGCGTGAGCTGCTGGCGC
AGATGGCGGGCGTGGACGTCCTCGTCACGCCCACGACGGCCACCACGGCGCCCCTCATTCCGGAGGCAGCGCTTCCGGAT
GGCGAGTCGAACCTGCCTGTCGTCGATGCCCTGATGCGCTTCGTGCGCCTGGCCAACCTGACGGGCTTCCCCTCGCTGTC
GGTGCCAGCCGGCTTCGATGAAGAGGGGCTCCCGGTGGGTGTCCAGCTCACAGGTCGCCCCTATGAGGAGCACCTGCTGC
TGCGCCTGGGCCGCGTGGTGGAGCAGGCCTCCGAGTACCGCGTCCCGCCTGTTCATCTGCGCGCACTTCGGTGA

Upstream 100 bases:

>100_bases
GCGTAGCCACGAAGTCCACGAAGACGCGAACGATGCGTGCTGCTGAATTGGCCACCATCGCCCATGCGGTATCGCCGGCT
CGGGGATAGGCTGCGGCGCC

Downstream 100 bases:

>100_bases
GCCGCGGTGGATTGAAGGGCTGAAAAACGAGTAAACCGTGTAAGTGTGGCCCCGCGTGCTCGCGGGGCCACCCACGGGCC
ACGCACTCGACACAGCCCGC

Product: amidase family protein

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MTYQRNPVKAPRVSGLALKAFVNALESGVGSVMLDKLTRDSGIERWRELPAGDAPPLQFPLAQGTAATESQTPTEQAARA
IAASASPPERESVAAYVRAYREGATDPVAVVNRIHESIARMDSGKQRLGLFIARKPDDVHRAAEASSERLREGRPLSVLD
GIPVVLKDEVDLAGFPTTLGTRFRTQVAAADSTVAARLKAAGAIILGKANMNEIGINPIGLNPHHGAARNPWDTGRITGG
SSSASAAAVAAGLCPLSIGADGGGSIRIPAALCGIVGLKATWGRIPETGVPPLCWNVGHVGPMGLTVDDVAAAYAVLAGP
DGHDLVSQGQSPHHLSGYEDEGLSGVRLGICWDYFEDADADVVARCKEAVAALSAAGARVVEIPPPDLNTVLWTHSCIIL
SEMSEVMLPHVKAHPSEFGLDTRTNLAIGRHFRATDLVHALRHRHRLTRELLAQMAGVDVLVTPTTATTAPLIPEAALPD
GESNLPVVDALMRFVRLANLTGFPSLSVPAGFDEEGLPVGVQLTGRPYEEHLLLRLGRVVEQASEYRVPPVHLRALR

Sequences:

>Translated_557_residues
MTYQRNPVKAPRVSGLALKAFVNALESGVGSVMLDKLTRDSGIERWRELPAGDAPPLQFPLAQGTAATESQTPTEQAARA
IAASASPPERESVAAYVRAYREGATDPVAVVNRIHESIARMDSGKQRLGLFIARKPDDVHRAAEASSERLREGRPLSVLD
GIPVVLKDEVDLAGFPTTLGTRFRTQVAAADSTVAARLKAAGAIILGKANMNEIGINPIGLNPHHGAARNPWDTGRITGG
SSSASAAAVAAGLCPLSIGADGGGSIRIPAALCGIVGLKATWGRIPETGVPPLCWNVGHVGPMGLTVDDVAAAYAVLAGP
DGHDLVSQGQSPHHLSGYEDEGLSGVRLGICWDYFEDADADVVARCKEAVAALSAAGARVVEIPPPDLNTVLWTHSCIIL
SEMSEVMLPHVKAHPSEFGLDTRTNLAIGRHFRATDLVHALRHRHRLTRELLAQMAGVDVLVTPTTATTAPLIPEAALPD
GESNLPVVDALMRFVRLANLTGFPSLSVPAGFDEEGLPVGVQLTGRPYEEHLLLRLGRVVEQASEYRVPPVHLRALR
>Mature_556_residues
TYQRNPVKAPRVSGLALKAFVNALESGVGSVMLDKLTRDSGIERWRELPAGDAPPLQFPLAQGTAATESQTPTEQAARAI
AASASPPERESVAAYVRAYREGATDPVAVVNRIHESIARMDSGKQRLGLFIARKPDDVHRAAEASSERLREGRPLSVLDG
IPVVLKDEVDLAGFPTTLGTRFRTQVAAADSTVAARLKAAGAIILGKANMNEIGINPIGLNPHHGAARNPWDTGRITGGS
SSASAAAVAAGLCPLSIGADGGGSIRIPAALCGIVGLKATWGRIPETGVPPLCWNVGHVGPMGLTVDDVAAAYAVLAGPD
GHDLVSQGQSPHHLSGYEDEGLSGVRLGICWDYFEDADADVVARCKEAVAALSAAGARVVEIPPPDLNTVLWTHSCIILS
EMSEVMLPHVKAHPSEFGLDTRTNLAIGRHFRATDLVHALRHRHRLTRELLAQMAGVDVLVTPTTATTAPLIPEAALPDG
ESNLPVVDALMRFVRLANLTGFPSLSVPAGFDEEGLPVGVQLTGRPYEEHLLLRLGRVVEQASEYRVPPVHLRALR

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=508, Percent_Identity=26.7716535433071, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI195972892, Length=490, Percent_Identity=25.3061224489796, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI166795287, Length=156, Percent_Identity=35.8974358974359, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17543272, Length=467, Percent_Identity=25.6959314775161, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17537465, Length=484, Percent_Identity=26.2396694214876, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17556264, Length=558, Percent_Identity=24.0143369175627, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990152, Length=576, Percent_Identity=22.7430555555556, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538252, Length=468, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538254, Length=447, Percent_Identity=26.1744966442953, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556278, Length=149, Percent_Identity=32.2147651006711, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17556276, Length=149, Percent_Identity=32.2147651006711, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319685, Length=395, Percent_Identity=29.3670886075949, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323950, Length=457, Percent_Identity=22.9759299781182, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24648113, Length=496, Percent_Identity=30.241935483871, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI161078093, Length=455, Percent_Identity=29.010989010989, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644968, Length=502, Percent_Identity=24.9003984063745, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356731, Length=517, Percent_Identity=25.9187620889749, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24652985, Length=438, Percent_Identity=24.6575342465753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19922090, Length=438, Percent_Identity=24.6575342465753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652981, Length=438, Percent_Identity=24.6575342465753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652983, Length=438, Percent_Identity=24.6575342465753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648435, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24648437, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45550774, Length=447, Percent_Identity=25.503355704698, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24648441, Length=434, Percent_Identity=25.3456221198157, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24648439, Length=434, Percent_Identity=25.3456221198157, Blast_Score=93, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 58875; Mature: 58744

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQRNPVKAPRVSGLALKAFVNALESGVGSVMLDKLTRDSGIERWRELPAGDAPPLQFP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LAQGTAATESQTPTEQAARAIAASASPPERESVAAYVRAYREGATDPVAVVNRIHESIAR
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MDSGKQRLGLFIARKPDDVHRAAEASSERLREGRPLSVLDGIPVVLKDEVDLAGFPTTLG
HCCCCHHEEEEEECCCHHHHHHHHHHHHHHHCCCCEEHHCCCCEEEECCCCCCCCCHHHH
TRFRTQVAAADSTVAARLKAAGAIILGKANMNEIGINPIGLNPHHGAARNPWDTGRITGG
HHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSSASAAAVAAGLCPLSIGADGGGSIRIPAALCGIVGLKATWGRIPETGVPPLCWNVGHV
CCCCHHHHHHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCC
GPMGLTVDDVAAAYAVLAGPDGHDLVSQGQSPHHLSGYEDEGLSGVRLGICWDYFEDADA
CCCCCCHHHHHHHHHHEECCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCH
DVVARCKEAVAALSAAGARVVEIPPPDLNTVLWTHSCIILSEMSEVMLPHVKAHPSEFGL
HHHHHHHHHHHHHHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCHHHCCCHHCCC
DTRTNLAIGRHFRATDLVHALRHRHRLTRELLAQMAGVDVLVTPTTATTAPLIPEAALPD
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCC
GESNLPVVDALMRFVRLANLTGFPSLSVPAGFDEEGLPVGVQLTGRPYEEHLLLRLGRVV
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
EQASEYRVPPVHLRALR
HHHHHCCCCCHHHEECC
>Mature Secondary Structure 
TYQRNPVKAPRVSGLALKAFVNALESGVGSVMLDKLTRDSGIERWRELPAGDAPPLQFP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LAQGTAATESQTPTEQAARAIAASASPPERESVAAYVRAYREGATDPVAVVNRIHESIAR
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MDSGKQRLGLFIARKPDDVHRAAEASSERLREGRPLSVLDGIPVVLKDEVDLAGFPTTLG
HCCCCHHEEEEEECCCHHHHHHHHHHHHHHHCCCCEEHHCCCCEEEECCCCCCCCCHHHH
TRFRTQVAAADSTVAARLKAAGAIILGKANMNEIGINPIGLNPHHGAARNPWDTGRITGG
HHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSSASAAAVAAGLCPLSIGADGGGSIRIPAALCGIVGLKATWGRIPETGVPPLCWNVGHV
CCCCHHHHHHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCC
GPMGLTVDDVAAAYAVLAGPDGHDLVSQGQSPHHLSGYEDEGLSGVRLGICWDYFEDADA
CCCCCCHHHHHHHHHHEECCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCH
DVVARCKEAVAALSAAGARVVEIPPPDLNTVLWTHSCIILSEMSEVMLPHVKAHPSEFGL
HHHHHHHHHHHHHHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCHHHCCCHHCCC
DTRTNLAIGRHFRATDLVHALRHRHRLTRELLAQMAGVDVLVTPTTATTAPLIPEAALPD
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCC
GESNLPVVDALMRFVRLANLTGFPSLSVPAGFDEEGLPVGVQLTGRPYEEHLLLRLGRVV
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
EQASEYRVPPVHLRALR
HHHHHCCCCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA