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The map label for this gene is clpC [H]

Identifier: 108761289

GI number: 108761289

Start: 6046572

End: 6049226

Strand: Reverse

Name: clpC [H]

Synonym: MXAN_4832

Alternate gene names: 108761289

Gene position: 6049226-6046572 (Counterclockwise)

Preceding gene: 108759300

Following gene: 108758815

Centisome position: 66.19

GC content: 68.21

Gene sequence:

>2655_bases
ATGGCCAATGTCTGCGACCTCTGCCACCAGCGCCCGGCGACCACCCGAGTCACCCGCGTCATGGGGAACCGGCGGACCAC
CGAGTCCCTGTGTGACGTCTGTAGCAGCCAGCGCTCGCGCTTCGGCCGCATGGGCCTGGGCACGTCGCTCTTCGACCAGT
TCTTCAGTGACTTCGGAGACGAGGACTTCGGGGGGCTGTCGCGTTCACTCCAGCAGCCGGTGGAGCGCTACGACATCACC
GAGGCCTTCTCCGATGAGACGCGGCGCGTATTGGAAGCGGCCTTCGAGGCGGCGCGAAGCGCGGGGGCGGCTTCCATCGA
CACGGAGCACCTGCTGGTGGCGCTCGCGAAGGACCCGCTGGGCCGGACCGCGCTCAGCCGCATGAAGCTGGACCCGGCCC
GCGTCGCCGAGCGCGCCGAGTCCGAGATGCGCCGTGGGAAGCGCCCCATGGAGCGTCCCGAGCTGTCGCCGCATGCGAAG
CGCGCCCTGGAACTCGCGTACCAGGAGGCCTACGAGCTGGGACATTCCTATGTGGGGCCCGAACACGTGCTGCTGGGGTT
GCTGCACGAAGGGGAAGGCCTGGCGTCGGAGATTCTGCGCGAGCAAGGGGCCCAGCACGGCAAGGCGCGCGCGGCCGTCG
CGGAAGCGCTGGCACCTTCATCCGAGGCACGCCGGTCGCCCACGCCCACGCTGGACGAGTACTGCCGCGACCTGACGAGC
CTGGCCTCGGAAGGGAAGCTGGACCCGGTGGTGGGGCGGGCCAACGAAATCGAGACCACGCTCGAAATCCTCTCGCGTCG
TACGAAGAACAACCCCGTGCTCATTGGTGAGCCGGGCGTGGGCAAGACGGCCATCGTGGAGGGCATTGCCCAGCGCATCA
TCTCCGCCGCGGTCCCGGACACGCTGCGCGACAAACGCGTGCTGCAACTGGACCTGTCCGGCCTGCTCGCGGGCAGCAAG
TACCGCGGTGAGTTCGAGGAGCGGCTGAAGAAGGTCATGGACGAGGTGAAGTCGCACAGCGAGGACATCGTCCTCTTCAT
CGACGAGATTCACACCATCGTCGGGGCGGGCGCGGCGGAGGGGGCCATGGATGCGGGCAACATGCTCAAGCCATCCCTGG
CGCGCGGCGAGCTGCACGTCATCGGCGCGACGACGTTGGATGAATACCGCAAGCGCATCGAGAAGGATGCTGCGCTCGAA
CGCCGCTTCCAGCCCGTGGTCGTCCCGGAGCCGACGGCCGAGCAGGCCATTGAGATTCTGCGAGGCCTCAAGGACCGCTA
CGAGTCCCACCACCGCGTGCGCATCGCGGACGAGGCGCTGGTGGCGGCGGTGGAGCTGTCGGACCGTTACGTCACAGGGC
GCTTCCTGCCGGACAAGGCCATCGACCTGGTGGACCAGGCGGCGGCCCGCGTGCGCTTGCGGCTCACGCTGCCACCGGAG
CGACTGGTGAATGCCGAGCATGAGGTGGTGAAGGTGAAGCGCTCGCTCGACGAGGCTCGCGGCCGGAAGGCGGGGCCGCG
CATCCAGGAGCTGGAGTCGAAGCTGAACGCCGCCGAGCGCGAGGTCCAGAGCGCGCAGAAGGAGCGCCGCACGCAGAAGT
CCGGTGAGACGCCGGAGGTCCGCGCCGAGGACGTGGCGGAGGTGCTGTCGCGCATGACGGGCATCCCCGTGACGCAGATG
ACGGAGGACGAGCGCAAGAAGCTGCTGGAGCTGGAGTCGCGGCTGCACGAGCGCGTCATCGGTCAGGACGAGGCCATCCG
CGTGTTGTCCCAGGCCATCCGGCGGGCGAGGGCGGGGCTCAAGGACGAGTCGCGCCCCATCGGCTCCTTCCTCTTCCTGG
GCCCCACGGGCGTGGGCAAGACGGAGTTGGCGAAGACGCTGGCGGAGCTGCTCTTCGGTGACGAGAAGGCGCTCATCCGC
TTCGACATGAGTGAGTACATGGAGAAGCACACCGTGAGCCGGCTGGTGGGCGCGCCGCCGGGCTATGTCGGCTACGAGGA
GGGCGGGCAGCTCACCGAGGCCGTGCGGCGGCGGCCCTACTCCGTGCTCCTCTTCGACGAGGTGGAGAAGGCCCACCCCG
ACGTGTTCCACATGCTGCTCCAGGTGCTGGATGACGGGCGGCTCACGGACGCGCAGGGCACGGTGGTGAACTTCAAGAAC
ACCGTCATCATCGGCACCAGCAACCTGGGCTCGCACCTCATCCAGGAGTCCACCGCGCGCAAGGAACCGCAGGAGCGCAT
GCGGGAGCGCGTCATGGGCGTGCTCAAGGGGCACTTCCCGCCCGAGTTCCTCAACCGCATCGACGAGACGGTGGTCTTCG
AGCCGCTCAACCGCGCGCAGCTGCGCGCCATCGTGGACCTGATGCTGGAGAAGACGCGCCGCCTGCTGCACGGCCAGGGC
ATTGACCTGGAGGTGACGCCCGCGGCGCTGGAAGCGCTGGTGGACAAGGGATGGGACCCAACCTTCGGCGCGCGTCCGCT
GCGGCGTGAAATCCAGCGCGCCATCGAGGCGCCACTCGCGGAGAAGCTCATCTCGGGCGACATCCATGAGAACAGCCGCG
TGAGAGCGGACTTCAAGGACGGAAAATTCCGGTTCGACGAAGTGGAGGCCGCTGAGGCGGAAGTCGCGCAGGCTGAAGCG
AGTGCCGTTCACTGA

Upstream 100 bases:

>100_bases
TGGGCCACCTTGGACGCCCGGCCCTGCCCTGGGGCCGAGGTGAGGCGCACCGGCCGTCCCTAGCGTTGGCATTGAACCGT
CGTTCGGGGGACCCGAAACC

Downstream 100 bases:

>100_bases
ACCGTCACGTGTGGGGTCATCCTGGCCCCCGAACATTCGCCTTGTAGTTGGTACGGACATGCCGGAGCCTTGGCGTGATG
CAGCCATCTCTTCCGGTCAT

Product: ATP-dependent Clp protease, ATP-binding subunit ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 884; Mature: 883

Protein sequence:

>884_residues
MANVCDLCHQRPATTRVTRVMGNRRTTESLCDVCSSQRSRFGRMGLGTSLFDQFFSDFGDEDFGGLSRSLQQPVERYDIT
EAFSDETRRVLEAAFEAARSAGAASIDTEHLLVALAKDPLGRTALSRMKLDPARVAERAESEMRRGKRPMERPELSPHAK
RALELAYQEAYELGHSYVGPEHVLLGLLHEGEGLASEILREQGAQHGKARAAVAEALAPSSEARRSPTPTLDEYCRDLTS
LASEGKLDPVVGRANEIETTLEILSRRTKNNPVLIGEPGVGKTAIVEGIAQRIISAAVPDTLRDKRVLQLDLSGLLAGSK
YRGEFEERLKKVMDEVKSHSEDIVLFIDEIHTIVGAGAAEGAMDAGNMLKPSLARGELHVIGATTLDEYRKRIEKDAALE
RRFQPVVVPEPTAEQAIEILRGLKDRYESHHRVRIADEALVAAVELSDRYVTGRFLPDKAIDLVDQAAARVRLRLTLPPE
RLVNAEHEVVKVKRSLDEARGRKAGPRIQELESKLNAAEREVQSAQKERRTQKSGETPEVRAEDVAEVLSRMTGIPVTQM
TEDERKKLLELESRLHERVIGQDEAIRVLSQAIRRARAGLKDESRPIGSFLFLGPTGVGKTELAKTLAELLFGDEKALIR
FDMSEYMEKHTVSRLVGAPPGYVGYEEGGQLTEAVRRRPYSVLLFDEVEKAHPDVFHMLLQVLDDGRLTDAQGTVVNFKN
TVIIGTSNLGSHLIQESTARKEPQERMRERVMGVLKGHFPPEFLNRIDETVVFEPLNRAQLRAIVDLMLEKTRRLLHGQG
IDLEVTPAALEALVDKGWDPTFGARPLRREIQRAIEAPLAEKLISGDIHENSRVRADFKDGKFRFDEVEAAEAEVAQAEA
SAVH

Sequences:

>Translated_884_residues
MANVCDLCHQRPATTRVTRVMGNRRTTESLCDVCSSQRSRFGRMGLGTSLFDQFFSDFGDEDFGGLSRSLQQPVERYDIT
EAFSDETRRVLEAAFEAARSAGAASIDTEHLLVALAKDPLGRTALSRMKLDPARVAERAESEMRRGKRPMERPELSPHAK
RALELAYQEAYELGHSYVGPEHVLLGLLHEGEGLASEILREQGAQHGKARAAVAEALAPSSEARRSPTPTLDEYCRDLTS
LASEGKLDPVVGRANEIETTLEILSRRTKNNPVLIGEPGVGKTAIVEGIAQRIISAAVPDTLRDKRVLQLDLSGLLAGSK
YRGEFEERLKKVMDEVKSHSEDIVLFIDEIHTIVGAGAAEGAMDAGNMLKPSLARGELHVIGATTLDEYRKRIEKDAALE
RRFQPVVVPEPTAEQAIEILRGLKDRYESHHRVRIADEALVAAVELSDRYVTGRFLPDKAIDLVDQAAARVRLRLTLPPE
RLVNAEHEVVKVKRSLDEARGRKAGPRIQELESKLNAAEREVQSAQKERRTQKSGETPEVRAEDVAEVLSRMTGIPVTQM
TEDERKKLLELESRLHERVIGQDEAIRVLSQAIRRARAGLKDESRPIGSFLFLGPTGVGKTELAKTLAELLFGDEKALIR
FDMSEYMEKHTVSRLVGAPPGYVGYEEGGQLTEAVRRRPYSVLLFDEVEKAHPDVFHMLLQVLDDGRLTDAQGTVVNFKN
TVIIGTSNLGSHLIQESTARKEPQERMRERVMGVLKGHFPPEFLNRIDETVVFEPLNRAQLRAIVDLMLEKTRRLLHGQG
IDLEVTPAALEALVDKGWDPTFGARPLRREIQRAIEAPLAEKLISGDIHENSRVRADFKDGKFRFDEVEAAEAEVAQAEA
SAVH
>Mature_883_residues
ANVCDLCHQRPATTRVTRVMGNRRTTESLCDVCSSQRSRFGRMGLGTSLFDQFFSDFGDEDFGGLSRSLQQPVERYDITE
AFSDETRRVLEAAFEAARSAGAASIDTEHLLVALAKDPLGRTALSRMKLDPARVAERAESEMRRGKRPMERPELSPHAKR
ALELAYQEAYELGHSYVGPEHVLLGLLHEGEGLASEILREQGAQHGKARAAVAEALAPSSEARRSPTPTLDEYCRDLTSL
ASEGKLDPVVGRANEIETTLEILSRRTKNNPVLIGEPGVGKTAIVEGIAQRIISAAVPDTLRDKRVLQLDLSGLLAGSKY
RGEFEERLKKVMDEVKSHSEDIVLFIDEIHTIVGAGAAEGAMDAGNMLKPSLARGELHVIGATTLDEYRKRIEKDAALER
RFQPVVVPEPTAEQAIEILRGLKDRYESHHRVRIADEALVAAVELSDRYVTGRFLPDKAIDLVDQAAARVRLRLTLPPER
LVNAEHEVVKVKRSLDEARGRKAGPRIQELESKLNAAEREVQSAQKERRTQKSGETPEVRAEDVAEVLSRMTGIPVTQMT
EDERKKLLELESRLHERVIGQDEAIRVLSQAIRRARAGLKDESRPIGSFLFLGPTGVGKTELAKTLAELLFGDEKALIRF
DMSEYMEKHTVSRLVGAPPGYVGYEEGGQLTEAVRRRPYSVLLFDEVEKAHPDVFHMLLQVLDDGRLTDAQGTVVNFKNT
VIIGTSNLGSHLIQESTARKEPQERMRERVMGVLKGHFPPEFLNRIDETVVFEPLNRAQLRAIVDLMLEKTRRLLHGQGI
DLEVTPAALEALVDKGWDPTFGARPLRREIQRAIEAPLAEKLISGDIHENSRVRADFKDGKFRFDEVEAAEAEVAQAEAS
AVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=40.8026755852843, Blast_Score=207, Evalue=3e-53,
Organism=Escherichia coli, GI1788943, Length=767, Percent_Identity=49.4132985658409, Blast_Score=723, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=817, Percent_Identity=37.9436964504284, Blast_Score=516, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6320464, Length=701, Percent_Identity=46.6476462196862, Blast_Score=619, Evalue=1e-178,
Organism=Saccharomyces cerevisiae, GI6323002, Length=810, Percent_Identity=40.2469135802469, Blast_Score=533, Evalue=1e-152,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 98278; Mature: 98147

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVCDLCHQRPATTRVTRVMGNRRTTESLCDVCSSQRSRFGRMGLGTSLFDQFFSDFGD
CCCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
EDFGGLSRSLQQPVERYDITEAFSDETRRVLEAAFEAARSAGAASIDTEHLLVALAKDPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
GRTALSRMKLDPARVAERAESEMRRGKRPMERPELSPHAKRALELAYQEAYELGHSYVGP
CHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH
EHVLLGLLHEGEGLASEILREQGAQHGKARAAVAEALAPSSEARRSPTPTLDEYCRDLTS
HHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHH
LASEGKLDPVVGRANEIETTLEILSRRTKNNPVLIGEPGVGKTAIVEGIAQRIISAAVPD
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCH
TLRDKRVLQLDLSGLLAGSKYRGEFEERLKKVMDEVKSHSEDIVLFIDEIHTIVGAGAAE
HHHCCHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCC
GAMDAGNMLKPSLARGELHVIGATTLDEYRKRIEKDAALERRFQPVVVPEPTAEQAIEIL
CCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
RGLKDRYESHHRVRIADEALVAAVELSDRYVTGRFLPDKAIDLVDQAAARVRLRLTLPPE
HHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHEEEEEECCHH
RLVNAEHEVVKVKRSLDEARGRKAGPRIQELESKLNAAEREVQSAQKERRTQKSGETPEV
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RAEDVAEVLSRMTGIPVTQMTEDERKKLLELESRLHERVIGQDEAIRVLSQAIRRARAGL
CHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
KDESRPIGSFLFLGPTGVGKTELAKTLAELLFGDEKALIRFDMSEYMEKHTVSRLVGAPP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCC
GYVGYEEGGQLTEAVRRRPYSVLLFDEVEKAHPDVFHMLLQVLDDGRLTDAQGTVVNFKN
CCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECC
TVIIGTSNLGSHLIQESTARKEPQERMRERVMGVLKGHFPPEFLNRIDETVVFEPLNRAQ
EEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHH
LRAIVDLMLEKTRRLLHGQGIDLEVTPAALEALVDKGWDPTFGARPLRREIQRAIEAPLA
HHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHH
EKLISGDIHENSRVRADFKDGKFRFDEVEAAEAEVAQAEASAVH
HHHHCCCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANVCDLCHQRPATTRVTRVMGNRRTTESLCDVCSSQRSRFGRMGLGTSLFDQFFSDFGD
CCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
EDFGGLSRSLQQPVERYDITEAFSDETRRVLEAAFEAARSAGAASIDTEHLLVALAKDPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
GRTALSRMKLDPARVAERAESEMRRGKRPMERPELSPHAKRALELAYQEAYELGHSYVGP
CHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH
EHVLLGLLHEGEGLASEILREQGAQHGKARAAVAEALAPSSEARRSPTPTLDEYCRDLTS
HHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHH
LASEGKLDPVVGRANEIETTLEILSRRTKNNPVLIGEPGVGKTAIVEGIAQRIISAAVPD
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCH
TLRDKRVLQLDLSGLLAGSKYRGEFEERLKKVMDEVKSHSEDIVLFIDEIHTIVGAGAAE
HHHCCHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCC
GAMDAGNMLKPSLARGELHVIGATTLDEYRKRIEKDAALERRFQPVVVPEPTAEQAIEIL
CCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
RGLKDRYESHHRVRIADEALVAAVELSDRYVTGRFLPDKAIDLVDQAAARVRLRLTLPPE
HHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHEEEEEECCHH
RLVNAEHEVVKVKRSLDEARGRKAGPRIQELESKLNAAEREVQSAQKERRTQKSGETPEV
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RAEDVAEVLSRMTGIPVTQMTEDERKKLLELESRLHERVIGQDEAIRVLSQAIRRARAGL
CHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
KDESRPIGSFLFLGPTGVGKTELAKTLAELLFGDEKALIRFDMSEYMEKHTVSRLVGAPP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCC
GYVGYEEGGQLTEAVRRRPYSVLLFDEVEKAHPDVFHMLLQVLDDGRLTDAQGTVVNFKN
CCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECC
TVIIGTSNLGSHLIQESTARKEPQERMRERVMGVLKGHFPPEFLNRIDETVVFEPLNRAQ
EEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHH
LRAIVDLMLEKTRRLLHGQGIDLEVTPAALEALVDKGWDPTFGARPLRREIQRAIEAPLA
HHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHH
EKLISGDIHENSRVRADFKDGKFRFDEVEAAEAEVAQAEASAVH
HHHHCCCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]