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The map label for this gene is plsC [H]

Identifier: 108761281

GI number: 108761281

Start: 3872898

End: 3873692

Strand: Reverse

Name: plsC [H]

Synonym: MXAN_3330

Alternate gene names: 108761281

Gene position: 3873692-3872898 (Counterclockwise)

Preceding gene: 108762434

Following gene: 108761841

Centisome position: 42.38

GC content: 67.8

Gene sequence:

>795_bases
ATGCGCAAGCTCTTTTGCATTTTCGTGGCGGGCGTCTGGACGCTCTTCTGTTTCCCCCTTGCCATCTTGGCGATGCTGCT
CACGCTCAACCCATCGCGCTCCGTCTGGGTGGCGCGCGAGCTCTGGTCGCCCGTGCTGCTGTGGGCAGGGGGCGCGAAGC
TGGAAGTCATCGGCCAGGAGAACGTGGACCCGAATCGGCCCACCATCTACGTGGCCAACCACCAGTCCACCATCGACATC
CCGGCGCACTTCCTGGCCGTCCCCATCCCTTTCCGCTACGTCGCCAAGACGCAGCTCAAGTGGGTGCCCCTTATCGGCTG
GTACCTCGCGCTCGCAGGCCACGTTTTCATCAACCGGTCCAACCGCTCCAAGGCCATCGCCTCGCTCAACGCGGCAGCGG
CCAAGATTCGCGGCGGCACCAGCATCTTCCTGTATCCGGAAGGCACCCGCTCGACGGACGGCCGCGTCCTGCCCTTCAAG
AAGGGCCCCTTCGCCCTGGCGCTGAAGGCCCGCGTCCCCGTCTGCCCCGTCACCATCGAGGGCTCCGGCGACCTGATGCC
CAAGTCCACCTGGAACATCACCCCCGGTCCCATCCGCGTGAAGATTGGCAAGCCCATCGACACGACCACGTTCGCCGAGA
ACGACCGCGAAGGGCTGGCCCGAGCCGTCCGCGCCGTCATCATCGCGGACAGCCTGTCCCTCGGGGGCAAGGGCGGCGAC
GTGGATGACGCCGTGGCCGCCGCGGGCGCCGAGGGCGTCAGCGACGCGCGCGCCCGAGCCCTCTCCTCCCCCTGA

Upstream 100 bases:

>100_bases
TCGCCGCCTGACCGTCTGGCCAGGGAGCTTCGGCGGGCAAGCCCGCGGGCCCGGGCACCTTCCGGCCCTGAACATCGGCC
CCCAGGAGGCGGGCTGAGGG

Downstream 100 bases:

>100_bases
GACGCCTCTCCGAGATGACCATTCGCCACCTCCGTTCCCGTCCCTGGATTCGCGCCGCGGTACTCGGCGTGGGCCTCCTG
ACTGGTTGCAGCACCACCTC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRKLFCIFVAGVWTLFCFPLAILAMLLTLNPSRSVWVARELWSPVLLWAGGAKLEVIGQENVDPNRPTIYVANHQSTIDI
PAHFLAVPIPFRYVAKTQLKWVPLIGWYLALAGHVFINRSNRSKAIASLNAAAAKIRGGTSIFLYPEGTRSTDGRVLPFK
KGPFALALKARVPVCPVTIEGSGDLMPKSTWNITPGPIRVKIGKPIDTTTFAENDREGLARAVRAVIIADSLSLGGKGGD
VDDAVAAAGAEGVSDARARALSSP

Sequences:

>Translated_264_residues
MRKLFCIFVAGVWTLFCFPLAILAMLLTLNPSRSVWVARELWSPVLLWAGGAKLEVIGQENVDPNRPTIYVANHQSTIDI
PAHFLAVPIPFRYVAKTQLKWVPLIGWYLALAGHVFINRSNRSKAIASLNAAAAKIRGGTSIFLYPEGTRSTDGRVLPFK
KGPFALALKARVPVCPVTIEGSGDLMPKSTWNITPGPIRVKIGKPIDTTTFAENDREGLARAVRAVIIADSLSLGGKGGD
VDDAVAAAGAEGVSDARARALSSP
>Mature_264_residues
MRKLFCIFVAGVWTLFCFPLAILAMLLTLNPSRSVWVARELWSPVLLWAGGAKLEVIGQENVDPNRPTIYVANHQSTIDI
PAHFLAVPIPFRYVAKTQLKWVPLIGWYLALAGHVFINRSNRSKAIASLNAAAAKIRGGTSIFLYPEGTRSTDGRVLPFK
KGPFALALKARVPVCPVTIEGSGDLMPKSTWNITPGPIRVKIGKPIDTTTFAENDREGLARAVRAVIIADSLSLGGKGGD
VDDAVAAAGAEGVSDARARALSSP

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=232, Percent_Identity=31.0344827586207, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI15100175, Length=232, Percent_Identity=31.0344827586207, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI6041665, Length=252, Percent_Identity=27.3809523809524, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1789395, Length=203, Percent_Identity=29.5566502463054, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17568319, Length=198, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17564032, Length=181, Percent_Identity=28.7292817679558, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320151, Length=212, Percent_Identity=33.0188679245283, Blast_Score=121, Evalue=9e-29,
Organism=Drosophila melanogaster, GI281364648, Length=241, Percent_Identity=29.8755186721992, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24582856, Length=241, Percent_Identity=29.8755186721992, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24582854, Length=241, Percent_Identity=29.8755186721992, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24641614, Length=196, Percent_Identity=30.1020408163265, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641612, Length=196, Percent_Identity=30.1020408163265, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28338; Mature: 28338

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLFCIFVAGVWTLFCFPLAILAMLLTLNPSRSVWVARELWSPVLLWAGGAKLEVIGQE
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCEEEEECCCEEEEEECC
NVDPNRPTIYVANHQSTIDIPAHFLAVPIPFRYVAKTQLKWVPLIGWYLALAGHVFINRS
CCCCCCCEEEEECCCCEEECCCEEEEECCCHHHHHHCCCEEEHHHHHHHHHHCEEEEECC
NRSKAIASLNAAAAKIRGGTSIFLYPEGTRSTDGRVLPFKKGPFALALKARVPVCPVTIE
CCCHHHHHHHHHHHEECCCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCEEEEEEC
GSGDLMPKSTWNITPGPIRVKIGKPIDTTTFAENDREGLARAVRAVIIADSLSLGGKGGD
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
VDDAVAAAGAEGVSDARARALSSP
HHHHHHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MRKLFCIFVAGVWTLFCFPLAILAMLLTLNPSRSVWVARELWSPVLLWAGGAKLEVIGQE
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCEEEEECCCEEEEEECC
NVDPNRPTIYVANHQSTIDIPAHFLAVPIPFRYVAKTQLKWVPLIGWYLALAGHVFINRS
CCCCCCCEEEEECCCCEEECCCEEEEECCCHHHHHHCCCEEEHHHHHHHHHHCEEEEECC
NRSKAIASLNAAAAKIRGGTSIFLYPEGTRSTDGRVLPFKKGPFALALKARVPVCPVTIE
CCCHHHHHHHHHHHEECCCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCEEEEEEC
GSGDLMPKSTWNITPGPIRVKIGKPIDTTTFAENDREGLARAVRAVIIADSLSLGGKGGD
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
VDDAVAAAGAEGVSDARARALSSP
HHHHHHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]