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The map label for this gene is cysQ [H]

Identifier: 108761261

GI number: 108761261

Start: 2756966

End: 2757799

Strand: Direct

Name: cysQ [H]

Synonym: MXAN_2369

Alternate gene names: 108761261

Gene position: 2756966-2757799 (Clockwise)

Preceding gene: 108758204

Following gene: 108763696

Centisome position: 30.16

GC content: 71.46

Gene sequence:

>834_bases
ATGCATCCGCTCGACGCCGAACTCGACATCGCCCGCCGCGTAGCCCGCCAGGCGGGAGCCATCCTCCTGGAGGTCTACGC
CACGCCCTTCGCCGTCCATGACAAGGCGGGAGGCATGGGGCCCGTCACCGAGGCCGACGAGCGCGCCAACGCCTTCATCG
TGGAAGCGCTGCGCGACGCATTTCCTTCCGACGGTGTCGTGGCCGAGGAGTCCGACAACACCTCCGGCGCGAGCCGCTTC
GAGCGCTGCTGGTTCGTGGACCCCATGGACGGCACGCAGGAGTTCGTCAACCGCAACGGCGAGTTCGCCATCCACATCGG
GCTCGCCATCGCGGGGAAGGCCACGCTGGGCGTCGTGTACCGGCCCGTTGGAGACACGCTGTACTGGGGCGTGGTGGGGC
AGGGCGGCTTCGTGGAGCACGCGAAGGGGCGCCGCGCCCTGCGGGTGTCGGACACGGCGGAGCCGTCCGCGCTGCGGCTG
GTGGTGTCCCGCTCACACCGCTCGCGCCTGACGGACGCGGTGGTCCGGCGGCTGGGCATCACGCACGAGCAGGCGTGCGG
CTCCGTGGGCCTCAAGTGCGGTCTGCTGGCGGAGGCCGCCTGCGACCTCTACCTGCACGTCAGCGACAAGAGCTATCGCT
GGGACAACTGCGCGCCCGAAGCGGTTCTGCGCGCGGCGGGCGGCATCCTCACGGACCTGGGCGGGACGCCGTACGCCTAT
GACGGTTCGGAGCTCCAGAACCGCCGCGGCCTGCTGGCCTGCAACGCCGCCGCCTTCGAGCACGTGGCGCCCGTGGTGGC
CGGATTCGCCCGCGAGGCCGGCATCCTTCGCTGA

Upstream 100 bases:

>100_bases
AGCCAGCCAGGGAAGGGCGCCACCTTCGTCGTCGACCTTCCCCTGGAGGCTCGCTGACCCGTGACTGGAGGAGGACGGAG
GGGCAGACTTCGGCCACCGC

Downstream 100 bases:

>100_bases
GGCCTCGCGGACGCCGCTCGCGTCAGGACGCCGTCGTCTCGCAGCGCTGGATGATGGTGCGCAACTGGGACTGCACGCCG
GAGAGCATGCTGCGCAGTCG

Product: putative 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MHPLDAELDIARRVARQAGAILLEVYATPFAVHDKAGGMGPVTEADERANAFIVEALRDAFPSDGVVAEESDNTSGASRF
ERCWFVDPMDGTQEFVNRNGEFAIHIGLAIAGKATLGVVYRPVGDTLYWGVVGQGGFVEHAKGRRALRVSDTAEPSALRL
VVSRSHRSRLTDAVVRRLGITHEQACGSVGLKCGLLAEAACDLYLHVSDKSYRWDNCAPEAVLRAAGGILTDLGGTPYAY
DGSELQNRRGLLACNAAAFEHVAPVVAGFAREAGILR

Sequences:

>Translated_277_residues
MHPLDAELDIARRVARQAGAILLEVYATPFAVHDKAGGMGPVTEADERANAFIVEALRDAFPSDGVVAEESDNTSGASRF
ERCWFVDPMDGTQEFVNRNGEFAIHIGLAIAGKATLGVVYRPVGDTLYWGVVGQGGFVEHAKGRRALRVSDTAEPSALRL
VVSRSHRSRLTDAVVRRLGITHEQACGSVGLKCGLLAEAACDLYLHVSDKSYRWDNCAPEAVLRAAGGILTDLGGTPYAY
DGSELQNRRGLLACNAAAFEHVAPVVAGFAREAGILR
>Mature_277_residues
MHPLDAELDIARRVARQAGAILLEVYATPFAVHDKAGGMGPVTEADERANAFIVEALRDAFPSDGVVAEESDNTSGASRF
ERCWFVDPMDGTQEFVNRNGEFAIHIGLAIAGKATLGVVYRPVGDTLYWGVVGQGGFVEHAKGRRALRVSDTAEPSALRL
VVSRSHRSRLTDAVVRRLGITHEQACGSVGLKCGLLAEAACDLYLHVSDKSYRWDNCAPEAVLRAAGGILTDLGGTPYAY
DGSELQNRRGLLACNAAAFEHVAPVVAGFAREAGILR

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=272, Percent_Identity=27.9411764705882, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI5031789, Length=272, Percent_Identity=27.9411764705882, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7657236, Length=254, Percent_Identity=29.5275590551181, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI116812595, Length=283, Percent_Identity=27.208480565371, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI221625507, Length=142, Percent_Identity=30.9859154929577, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI157388900, Length=243, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1790659, Length=241, Percent_Identity=36.9294605809129, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788882, Length=251, Percent_Identity=30.2788844621514, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193202572, Length=261, Percent_Identity=27.9693486590038, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193202570, Length=264, Percent_Identity=27.6515151515151, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71995905, Length=246, Percent_Identity=30.0813008130081, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71995897, Length=246, Percent_Identity=30.0813008130081, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17537869, Length=289, Percent_Identity=31.4878892733564, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24651149, Length=286, Percent_Identity=29.3706293706294, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24664922, Length=282, Percent_Identity=27.6595744680851, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357957, Length=248, Percent_Identity=27.0161290322581, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24664918, Length=242, Percent_Identity=28.5123966942149, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24664926, Length=236, Percent_Identity=26.6949152542373, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357329, Length=285, Percent_Identity=25.2631578947368, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29619; Mature: 29619

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPLDAELDIARRVARQAGAILLEVYATPFAVHDKAGGMGPVTEADERANAFIVEALRDA
CCCCCCHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
FPSDGVVAEESDNTSGASRFERCWFVDPMDGTQEFVNRNGEFAIHIGLAIAGKATLGVVY
CCCCCEEEECCCCCCCHHHHHHEEEECCCCHHHHHHCCCCCEEEEEEEEEECCCEEEEEE
RPVGDTLYWGVVGQGGFVEHAKGRRALRVSDTAEPSALRLVVSRSHRSRLTDAVVRRLGI
ECCCCEEEEEEECCCCCEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
THEQACGSVGLKCGLLAEAACDLYLHVSDKSYRWDNCAPEAVLRAAGGILTDLGGTPYAY
CHHHHHHCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEECCCCCCCEE
DGSELQNRRGLLACNAAAFEHVAPVVAGFAREAGILR
CCHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHPLDAELDIARRVARQAGAILLEVYATPFAVHDKAGGMGPVTEADERANAFIVEALRDA
CCCCCCHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
FPSDGVVAEESDNTSGASRFERCWFVDPMDGTQEFVNRNGEFAIHIGLAIAGKATLGVVY
CCCCCEEEECCCCCCCHHHHHHEEEECCCCHHHHHHCCCCCEEEEEEEEEECCCEEEEEE
RPVGDTLYWGVVGQGGFVEHAKGRRALRVSDTAEPSALRLVVSRSHRSRLTDAVVRRLGI
ECCCCEEEEEEECCCCCEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
THEQACGSVGLKCGLLAEAACDLYLHVSDKSYRWDNCAPEAVLRAAGGILTDLGGTPYAY
CHHHHHHCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEECCCCCCCEE
DGSELQNRRGLLACNAAAFEHVAPVVAGFAREAGILR
CCHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]