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The map label for this gene is kynA [H]

Identifier: 108761141

GI number: 108761141

Start: 832589

End: 833437

Strand: Reverse

Name: kynA [H]

Synonym: MXAN_0731

Alternate gene names: 108761141

Gene position: 833437-832589 (Counterclockwise)

Preceding gene: 108759656

Following gene: 108758309

Centisome position: 9.12

GC content: 69.02

Gene sequence:

>849_bases
ATGAGCGCGTCCATCGATTACAGTCACGCCGAAAAACTACGACTCGAACTGGCAGAACCCCTCTTCAACCCCCTCTTGAA
GAAGTGGGTGGGCAAGGGCGAGCTCGATTACGAGGTCTACCTCAAGACGCCCACGCTGCTGTCGCTGCAGGCGCCGGACG
GCGAGCGCGTCGCCCACGACGAGCTGATGTTCCAGGTGGTGCACCAGGCGCAGGAGCTCTGGCTGAAGCTGGCCTCGCGC
GAGGCGGTGGAAGTCGTAGCCGAGCTGGACCGGGACGCGCTGTGGGCCGCCTCGTCGCGGCTGGAGCGCATCTGCCGGGT
GCTCCAGGCGGTGAAGCAGGAGCTGGCCATCCTGGAGACGATGACGCCGGACACCTACCAGGTCATCCGGCGCAGCCTGG
GCAACGGCAGCGGCCAGGAGTCCCCCGGCTACAACATGCTGCGGCGGGTAGCGCTGGGGCTGGAAGGCGCCCTGGACCGG
CTGCTCGCGCGGCGCGGGCTGGCGCTGGCGTCCGTGTACACCTCGGGTGGCCCGGACGACTTGAAGCGAATCTGCGAGCA
GTTGGTGGACATGGACGAGGCCTTCCAGGGCTGGCTCCATGCGCACTTCCAGCTGGTGCGCCGCACCATTGGCGTGGACC
GCACCGTGAAAGCGCTGGACGGCCTGCCCACGCAGGTGCTCGCGGGGCGGATGATGCTGCCGCTGTTCCGCCAGCTCTGG
GACGTGCGGCTGGAGCTGACGTCCGGGTGGCAGCGCGAGGGCGGCATCGCCCCGGGTGCCAACCGGGCCCCTCCAGGCGG
CGGCTGCCCCATGGCGCACGCGGCCAGAATGCAGGTGGAACAGCCATGA

Upstream 100 bases:

>100_bases
GCTCCCACCAGCTGAACGCCGGATGACATGCCCGCGGGTCCCGTTGGGACGGGGCCCGCGATTCCACACCTTCCGAGCTC
CCCCCACTCAGGAGGGCCGT

Downstream 100 bases:

>100_bases
AGGGGGAGGCCACGGCCCTGGCTTCCACCCCTCGCGCACTGCTTCACCTGCTGTACAACGGCGCCCGCGCCGTGGACGTC
CTGGAGGCCTCCCTGGACCT

Product: hypothetical protein

Products: NA

Alternate protein names: TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSASIDYSHAEKLRLELAEPLFNPLLKKWVGKGELDYEVYLKTPTLLSLQAPDGERVAHDELMFQVVHQAQELWLKLASR
EAVEVVAELDRDALWAASSRLERICRVLQAVKQELAILETMTPDTYQVIRRSLGNGSGQESPGYNMLRRVALGLEGALDR
LLARRGLALASVYTSGGPDDLKRICEQLVDMDEAFQGWLHAHFQLVRRTIGVDRTVKALDGLPTQVLAGRMMLPLFRQLW
DVRLELTSGWQREGGIAPGANRAPPGGGCPMAHAARMQVEQP

Sequences:

>Translated_282_residues
MSASIDYSHAEKLRLELAEPLFNPLLKKWVGKGELDYEVYLKTPTLLSLQAPDGERVAHDELMFQVVHQAQELWLKLASR
EAVEVVAELDRDALWAASSRLERICRVLQAVKQELAILETMTPDTYQVIRRSLGNGSGQESPGYNMLRRVALGLEGALDR
LLARRGLALASVYTSGGPDDLKRICEQLVDMDEAFQGWLHAHFQLVRRTIGVDRTVKALDGLPTQVLAGRMMLPLFRQLW
DVRLELTSGWQREGGIAPGANRAPPGGGCPMAHAARMQVEQP
>Mature_281_residues
SASIDYSHAEKLRLELAEPLFNPLLKKWVGKGELDYEVYLKTPTLLSLQAPDGERVAHDELMFQVVHQAQELWLKLASRE
AVEVVAELDRDALWAASSRLERICRVLQAVKQELAILETMTPDTYQVIRRSLGNGSGQESPGYNMLRRVALGLEGALDRL
LARRGLALASVYTSGGPDDLKRICEQLVDMDEAFQGWLHAHFQLVRRTIGVDRTVKALDGLPTQVLAGRMMLPLFRQLWD
VRLELTSGWQREGGIAPGANRAPPGGGCPMAHAARMQVEQP

Specific function: Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring [H]

COG id: COG3483

COG function: function code E; Tryptophan 2,3-dioxygenase (vermilion)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tryptophan 2,3-dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004981 [H]

Pfam domain/function: PF03301 Trp_dioxygenase [H]

EC number: =1.13.11.11 [H]

Molecular weight: Translated: 31414; Mature: 31282

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASIDYSHAEKLRLELAEPLFNPLLKKWVGKGELDYEVYLKTPTLLSLQAPDGERVAHD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCHHHHH
ELMFQVVHQAQELWLKLASREAVEVVAELDRDALWAASSRLERICRVLQAVKQELAILET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTPDTYQVIRRSLGNGSGQESPGYNMLRRVALGLEGALDRLLARRGLALASVYTSGGPDD
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHH
LKRICEQLVDMDEAFQGWLHAHFQLVRRTIGVDRTVKALDGLPTQVLAGRMMLPLFRQLW
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
DVRLELTSGWQREGGIAPGANRAPPGGGCPMAHAARMQVEQP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SASIDYSHAEKLRLELAEPLFNPLLKKWVGKGELDYEVYLKTPTLLSLQAPDGERVAHD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCHHHHH
ELMFQVVHQAQELWLKLASREAVEVVAELDRDALWAASSRLERICRVLQAVKQELAILET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTPDTYQVIRRSLGNGSGQESPGYNMLRRVALGLEGALDRLLARRGLALASVYTSGGPDD
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHH
LKRICEQLVDMDEAFQGWLHAHFQLVRRTIGVDRTVKALDGLPTQVLAGRMMLPLFRQLW
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
DVRLELTSGWQREGGIAPGANRAPPGGGCPMAHAARMQVEQP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]