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The map label for this gene is fadR [H]

Identifier: 108761069

GI number: 108761069

Start: 3164307

End: 3165008

Strand: Direct

Name: fadR [H]

Synonym: MXAN_2711

Alternate gene names: 108761069

Gene position: 3164307-3165008 (Clockwise)

Preceding gene: 108759436

Following gene: 108757470

Centisome position: 34.62

GC content: 69.52

Gene sequence:

>702_bases
GTGGGTCAGCAGAGCAAGCCGGCGGCGGAGAGTGGCACGCGCGAAAGCGAGCGCCGCCGCACCATCCTCCGCGCGGCCAT
CGACGTGTTCGCGCGCAAGGGCTACCACGGCTGCCGCATCGCGGACGTGGCGAAGGAGGCCGGCGTCGCGTACGGGCTCG
TCTACCACTACTTCAAGAACAAGGATGAGCTGCTCGAGACGGTGTTCGACACTGGCTGGAGCGGCTTCGTCACGCGCGTG
CGCGCGGTGGTGGAGGGCGAAGGCCCCCTGGCGGAGAAGGTCCGCGGCATCGTCGAGGTGGCCTTCGAGGCCTACCGGGT
GGATCCGCGCGCGGTGAAGGTGCTCATCCTGGAGATTGCGCGCAGCCCGGCGGGCTCGCGCATCAACCGGCAGACGGCCT
TCGTGGATGCCATCCGGCTCAGCTCGGCGCTCTTCAACGCCGCGCAGGAGCGGGGCGAGCTGCGGCCGGGGTTGGACCCG
CACCTGGCCTCCGCGCTCCTCTTCGGCAACATCGAAATGGCGCTCACCGCCTTCGTCGTGGGGCTGGCCGACGCGCGCGA
CCCCGACGCCCTGGAGCGGGCGAAGTCGCAGATTGCCGACTCCTTCCTTTACGGCGTCCTCACGGGTGCCCAGGCAGCGG
AGGTGTCCGAATGGAAGCCGGAGAAGTCCGCTACGAAGTCCAAGGCACCCAAGCGCTCCTGA

Upstream 100 bases:

>100_bases
GTTTCGCCGGGCGGGCCCACGAAGGCATTGACCCCAGGGCCCGCCCTCCGTAGGTTCTCCGCTGGTTGACTGGCGAATCA
CCCGCCGGTGGAGGACAACC

Downstream 100 bases:

>100_bases
CCATTGACCGGCCCAAGGCCCGCAACGCCTTGTCCCCGGCGGTGGTGCGCGAGCTGATGGCCGCGCTGGAGCGGGCCGAA
TCCGACACCTCGGTGCGCGT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MGQQSKPAAESGTRESERRRTILRAAIDVFARKGYHGCRIADVAKEAGVAYGLVYHYFKNKDELLETVFDTGWSGFVTRV
RAVVEGEGPLAEKVRGIVEVAFEAYRVDPRAVKVLILEIARSPAGSRINRQTAFVDAIRLSSALFNAAQERGELRPGLDP
HLASALLFGNIEMALTAFVVGLADARDPDALERAKSQIADSFLYGVLTGAQAAEVSEWKPEKSATKSKAPKRS

Sequences:

>Translated_233_residues
MGQQSKPAAESGTRESERRRTILRAAIDVFARKGYHGCRIADVAKEAGVAYGLVYHYFKNKDELLETVFDTGWSGFVTRV
RAVVEGEGPLAEKVRGIVEVAFEAYRVDPRAVKVLILEIARSPAGSRINRQTAFVDAIRLSSALFNAAQERGELRPGLDP
HLASALLFGNIEMALTAFVVGLADARDPDALERAKSQIADSFLYGVLTGAQAAEVSEWKPEKSATKSKAPKRS
>Mature_232_residues
GQQSKPAAESGTRESERRRTILRAAIDVFARKGYHGCRIADVAKEAGVAYGLVYHYFKNKDELLETVFDTGWSGFVTRVR
AVVEGEGPLAEKVRGIVEVAFEAYRVDPRAVKVLILEIARSPAGSRINRQTAFVDAIRLSSALFNAAQERGELRPGLDPH
LASALLFGNIEMALTAFVVGLADARDPDALERAKSQIADSFLYGVLTGAQAAEVSEWKPEKSATKSKAPKRS

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25378; Mature: 25247

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQSKPAAESGTRESERRRTILRAAIDVFARKGYHGCRIADVAKEAGVAYGLVYHYFKN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
KDELLETVFDTGWSGFVTRVRAVVEGEGPLAEKVRGIVEVAFEAYRVDPRAVKVLILEIA
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RSPAGSRINRQTAFVDAIRLSSALFNAAQERGELRPGLDPHLASALLFGNIEMALTAFVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
GLADARDPDALERAKSQIADSFLYGVLTGAQAAEVSEWKPEKSATKSKAPKRS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
GQQSKPAAESGTRESERRRTILRAAIDVFARKGYHGCRIADVAKEAGVAYGLVYHYFKN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
KDELLETVFDTGWSGFVTRVRAVVEGEGPLAEKVRGIVEVAFEAYRVDPRAVKVLILEIA
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RSPAGSRINRQTAFVDAIRLSSALFNAAQERGELRPGLDPHLASALLFGNIEMALTAFVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
GLADARDPDALERAKSQIADSFLYGVLTGAQAAEVSEWKPEKSATKSKAPKRS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]