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The map label for this gene is yacO [H]

Identifier: 108761000

GI number: 108761000

Start: 3592108

End: 3592956

Strand: Direct

Name: yacO [H]

Synonym: MXAN_3063

Alternate gene names: 108761000

Gene position: 3592108-3592956 (Clockwise)

Preceding gene: 108757864

Following gene: 108763678

Centisome position: 39.3

GC content: 70.67

Gene sequence:

>849_bases
ATGCGTGAGCGTTCTTCCAAGGGCGGCCGTGGTGGTGAGCGCGCAAGCGAAGAAGTCCCCCAGCGCGCCAGCCGGGGCGA
GCGCGGAGGCGGCGAAGCCTCCCGTTTCGTCTACGGGGTGAATCCCGTCCTGGCGGCCCTTCGGGCCCGGCCGGACGAGG
TGGAGCGCTTGTTCCTGGTGGAGGGGCAGCTCGGCGCCCGAGCGGCGGGAGAGCTGCTCAGCCGGGCTCGCGAGTTCGGC
ATTCGCGTGGAGAAGGTGACGCGCGAGCGCCTGGGTACGCTGGCGGAGGGCGGCGTTCACCAGGGCGTGGTGGTCGAGCT
GCGCGGCTTCAAGTACGCGGAGCTGGAGGATCTCCTGGAGGCCGCGAAGGCACTGGGACAGCCTCCCCTGGTGGTCGTGC
TGGACGGAATCCAGGACCCGCACAATCTGGGAGCCATCATCCGCTCCGCGGATGCGCTGGGGGCCCACGGCGTGGTGATT
GCCAAGGACCGGGCGGTGCAGGTGACGGGCACCGTGGCCAAGGCGTCCGCCGGGGCCGTGGAGCACAGCCGCATCGCGCG
GGTGGTGAACATCTCCCGGGCTCTGGAGGAACTGAAGGAAGCCGGCCTGTGGGTCGCCGCGGCGGACGTCGACGCCAAGG
AGCCCATGTGGAGTGCCCGGCTCGACGGGCCGTTGGCGCTCGTCGTGGGGGCCGAGGGGGCAGGCGTCCGGGACGGAGTG
CTCAAGCACTGCGACTTCCGCCTCCGGATTCCGATGGCGGGTCAGGTCGGTTCATTGAATGCATCCGTTTCGGCCGGCAT
TCTGCTATACGAGGTCGCCCGCCAGCGGGGCACCGTCTCCGGCCGGTAG

Upstream 100 bases:

>100_bases
CTCCGTGGACGCGAAGCTCGTCTTCTTCATCTGCACGGAGAAGATCTGCGCACGTCAGCAGAAGACCTTCTCCCTTCCTG
TCGAGGTCCTCTGAGTTCCC

Downstream 100 bases:

>100_bases
CTGAAGTTTGGGATCAATCTCCTTGACTTGGGCGAACGGGAATTCTAGAAGGGCGCCCCTCTCAGGGCGGTGACGGGTGG
TTGACGGAGTCGCTGGGGCG

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRERSSKGGRGGERASEEVPQRASRGERGGGEASRFVYGVNPVLAALRARPDEVERLFLVEGQLGARAAGELLSRAREFG
IRVEKVTRERLGTLAEGGVHQGVVVELRGFKYAELEDLLEAAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGVVI
AKDRAVQVTGTVAKASAGAVEHSRIARVVNISRALEELKEAGLWVAAADVDAKEPMWSARLDGPLALVVGAEGAGVRDGV
LKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQRGTVSGR

Sequences:

>Translated_282_residues
MRERSSKGGRGGERASEEVPQRASRGERGGGEASRFVYGVNPVLAALRARPDEVERLFLVEGQLGARAAGELLSRAREFG
IRVEKVTRERLGTLAEGGVHQGVVVELRGFKYAELEDLLEAAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGVVI
AKDRAVQVTGTVAKASAGAVEHSRIARVVNISRALEELKEAGLWVAAADVDAKEPMWSARLDGPLALVVGAEGAGVRDGV
LKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQRGTVSGR
>Mature_282_residues
MRERSSKGGRGGERASEEVPQRASRGERGGGEASRFVYGVNPVLAALRARPDEVERLFLVEGQLGARAAGELLSRAREFG
IRVEKVTRERLGTLAEGGVHQGVVVELRGFKYAELEDLLEAAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGVVI
AKDRAVQVTGTVAKASAGAVEHSRIARVVNISRALEELKEAGLWVAAADVDAKEPMWSARLDGPLALVVGAEGAGVRDGV
LKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQRGTVSGR

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=301, Percent_Identity=32.2259136212625, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1790623, Length=245, Percent_Identity=38.3673469387755, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1788935, Length=239, Percent_Identity=29.2887029288703, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790083, Length=177, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555908, Length=262, Percent_Identity=32.0610687022901, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6324775, Length=285, Percent_Identity=28.7719298245614, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29767; Mature: 29767

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRERSSKGGRGGERASEEVPQRASRGERGGGEASRFVYGVNPVLAALRARPDEVERLFLV
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHEEEECCHHHHHHHCCCCHHHEEEEE
EGQLGARAAGELLSRAREFGIRVEKVTRERLGTLAEGGVHQGVVVELRGFKYAELEDLLE
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHH
AAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGVVIAKDRAVQVTGTVAKASAGAV
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHCCCCH
EHSRIARVVNISRALEELKEAGLWVAAADVDAKEPMWSARLDGPLALVVGAEGAGVRDGV
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCHHHH
LKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQRGTVSGR
HHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRERSSKGGRGGERASEEVPQRASRGERGGGEASRFVYGVNPVLAALRARPDEVERLFLV
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHEEEECCHHHHHHHCCCCHHHEEEEE
EGQLGARAAGELLSRAREFGIRVEKVTRERLGTLAEGGVHQGVVVELRGFKYAELEDLLE
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHH
AAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGVVIAKDRAVQVTGTVAKASAGAV
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHCCCCH
EHSRIARVVNISRALEELKEAGLWVAAADVDAKEPMWSARLDGPLALVVGAEGAGVRDGV
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCHHHH
LKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQRGTVSGR
HHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]