Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 108760958

GI number: 108760958

Start: 5123199

End: 5124431

Strand: Reverse

Name: macB [H]

Synonym: MXAN_4172

Alternate gene names: 108760958

Gene position: 5124431-5123199 (Counterclockwise)

Preceding gene: 108763012

Following gene: 108762019

Centisome position: 56.07

GC content: 67.4

Gene sequence:

>1233_bases
ATGCGAGCGTTCCTGGACAATTTGCGGTTGGCGTTGGGCACCTTCCTGGGCAACCCGCTGCGCTCGCTGTTGACGCTGCT
GGGCATCGTCATTGGCGTGGCGACGGTCATCACCATGATGGGGCTCATCGAGGGCCTGCGGGTCAAGGTGAACAACGACC
TGGGACGGATGGGGGCCCACACCTTCCAGGTGACGAAGTGGCCCGCGGGCGGCTTCGGGCGCATCAACTGGGCCAAGTTC
GCCAAGCGCAAGGACTTCGAGATGCCCGACTCGCGGGCCATCGAGGAGTCCTGCCCGTCGGTGGGGACGGTCGTGCCCAC
CGACGACGAGGGTGGCCAGAAGCTGGCCACGGCGAGCTCGGAGACGCGGCCGTCGGTCCGCGTGTTCGGCACGCCCGCCA
ACTACCCGCTGGTGAGCGGGGTGTCGGTGCAGGCCGGGCGCTACTTCAACGAAGTGGAGGCGCTGGACGGCCGCTATGTG
GCGCTGCTGGGGACGGACGTGTCGGACGCGCTGTTTCCGGGCATGAATCCGGTGGGCCACGAGGTGCGCATCAAGGGCCG
GCCCTTCCGCGTCATCGGCCTGCTCCAGAAGCGGGGGAGCATGCTGGGCATGTTCAGCCTGGACAACCAGGTGATGATTC
CGCTGAGCGTCTTCCACCAGCTCTACGGGAAGAAGCGCTCGCTGGACATCAGCGTGCAGGCGAAGTCCCCGGAGCTGTTC
AGCAAGGCGCAGGACGAGGTGGCCTCGCTGATGCGCCGGCGCCGCGACGTTCCGGCGAACATGCCCAACGACTTTGAATT
ACACACGAACGAGTCGGTGACGGCGTCGTTCAATCAGCTCTCCCAGGTCATCACCATCGCGGGCGTGGGCGTGTGCCTGC
TGTCCCTGGTGGTGGGCGGCATCGGCATCCTCAACATCATGCTGGTGTCGGTGATGGAGCGGACGCGGGAGATTGGCGTG
CGCAAGGCGCTGGGCGCGCGCAAGCGCCGCATCCTGGGACAGTTCGCCACGGAGGCGGTGCTGCTGTCGCTGATGGGCGG
CGCCCTGGGCCTGGGCCTGGGCTTCGGGCTGGTGTTCCTGGGCAACTGGATGATGGGCTTTCCCATGCAGGTGCCCCCGT
GGGCGGTGGGCCTGGCCCTGTTCATGAGCTGCGGCGTGGGGCTCCTGTTCGGCATCTACCCGGCGGCCCGCGCGGCGAAG
TTGGATCCGGTGGAGGCCATGCGGGCGGATTGA

Upstream 100 bases:

>100_bases
GTGGGCTTCGCCGCGCTGGTGGGCCTGCTGTTCGGCATCTGGCCGGCGGCGCGCGCGGCGAACCTGGACCCCGTGGAAGC
CCTTCGTTACGAGTAGCGCG

Downstream 100 bases:

>100_bases
GGGCGGTGGTTCCCGGTGACGGGCGCCACCCTTCGCGTTAAGCACAGCCCATGGCGCCTCGCATTGGAACGCTCTGGGAC
TCCGTCGGAAACACCCCGCT

Product: putative ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRAFLDNLRLALGTFLGNPLRSLLTLLGIVIGVATVITMMGLIEGLRVKVNNDLGRMGAHTFQVTKWPAGGFGRINWAKF
AKRKDFEMPDSRAIEESCPSVGTVVPTDDEGGQKLATASSETRPSVRVFGTPANYPLVSGVSVQAGRYFNEVEALDGRYV
ALLGTDVSDALFPGMNPVGHEVRIKGRPFRVIGLLQKRGSMLGMFSLDNQVMIPLSVFHQLYGKKRSLDISVQAKSPELF
SKAQDEVASLMRRRRDVPANMPNDFELHTNESVTASFNQLSQVITIAGVGVCLLSLVVGGIGILNIMLVSVMERTREIGV
RKALGARKRRILGQFATEAVLLSLMGGALGLGLGFGLVFLGNWMMGFPMQVPPWAVGLALFMSCGVGLLFGIYPAARAAK
LDPVEAMRAD

Sequences:

>Translated_410_residues
MRAFLDNLRLALGTFLGNPLRSLLTLLGIVIGVATVITMMGLIEGLRVKVNNDLGRMGAHTFQVTKWPAGGFGRINWAKF
AKRKDFEMPDSRAIEESCPSVGTVVPTDDEGGQKLATASSETRPSVRVFGTPANYPLVSGVSVQAGRYFNEVEALDGRYV
ALLGTDVSDALFPGMNPVGHEVRIKGRPFRVIGLLQKRGSMLGMFSLDNQVMIPLSVFHQLYGKKRSLDISVQAKSPELF
SKAQDEVASLMRRRRDVPANMPNDFELHTNESVTASFNQLSQVITIAGVGVCLLSLVVGGIGILNIMLVSVMERTREIGV
RKALGARKRRILGQFATEAVLLSLMGGALGLGLGFGLVFLGNWMMGFPMQVPPWAVGLALFMSCGVGLLFGIYPAARAAK
LDPVEAMRAD
>Mature_410_residues
MRAFLDNLRLALGTFLGNPLRSLLTLLGIVIGVATVITMMGLIEGLRVKVNNDLGRMGAHTFQVTKWPAGGFGRINWAKF
AKRKDFEMPDSRAIEESCPSVGTVVPTDDEGGQKLATASSETRPSVRVFGTPANYPLVSGVSVQAGRYFNEVEALDGRYV
ALLGTDVSDALFPGMNPVGHEVRIKGRPFRVIGLLQKRGSMLGMFSLDNQVMIPLSVFHQLYGKKRSLDISVQAKSPELF
SKAQDEVASLMRRRRDVPANMPNDFELHTNESVTASFNQLSQVITIAGVGVCLLSLVVGGIGILNIMLVSVMERTREIGV
RKALGARKRRILGQFATEAVLLSLMGGALGLGLGFGLVFLGNWMMGFPMQVPPWAVGLALFMSCGVGLLFGIYPAARAAK
LDPVEAMRAD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=412, Percent_Identity=33.7378640776699, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44298; Mature: 44298

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFLDNLRLALGTFLGNPLRSLLTLLGIVIGVATVITMMGLIEGLRVKVNNDLGRMGAH
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCCC
TFQVTKWPAGGFGRINWAKFAKRKDFEMPDSRAIEESCPSVGTVVPTDDEGGQKLATASS
EEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCEECCCCCCCCEEECCCC
ETRPSVRVFGTPANYPLVSGVSVQAGRYFNEVEALDGRYVALLGTDVSDALFPGMNPVGH
CCCCCEEEEECCCCCCEECCCEECCCHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCCCC
EVRIKGRPFRVIGLLQKRGSMLGMFSLDNQVMIPLSVFHQLYGKKRSLDISVQAKSPELF
EEEECCCCCHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHCCCCCEEEEEEECCCHHH
SKAQDEVASLMRRRRDVPANMPNDFELHTNESVTASFNQLSQVITIAGVGVCLLSLVVGG
HHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGILNIMLVSVMERTREIGVRKALGARKRRILGQFATEAVLLSLMGGALGLGLGFGLVFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNWMMGFPMQVPPWAVGLALFMSCGVGLLFGIYPAARAAKLDPVEAMRAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
>Mature Secondary Structure
MRAFLDNLRLALGTFLGNPLRSLLTLLGIVIGVATVITMMGLIEGLRVKVNNDLGRMGAH
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCCC
TFQVTKWPAGGFGRINWAKFAKRKDFEMPDSRAIEESCPSVGTVVPTDDEGGQKLATASS
EEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCEECCCCCCCCEEECCCC
ETRPSVRVFGTPANYPLVSGVSVQAGRYFNEVEALDGRYVALLGTDVSDALFPGMNPVGH
CCCCCEEEEECCCCCCEECCCEECCCHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCCCC
EVRIKGRPFRVIGLLQKRGSMLGMFSLDNQVMIPLSVFHQLYGKKRSLDISVQAKSPELF
EEEECCCCCHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHCCCCCEEEEEEECCCHHH
SKAQDEVASLMRRRRDVPANMPNDFELHTNESVTASFNQLSQVITIAGVGVCLLSLVVGG
HHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGILNIMLVSVMERTREIGVRKALGARKRRILGQFATEAVLLSLMGGALGLGLGFGLVFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNWMMGFPMQVPPWAVGLALFMSCGVGLLFGIYPAARAAKLDPVEAMRAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA