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The map label for this gene is malF [H]

Identifier: 108760888

GI number: 108760888

Start: 6697789

End: 6699969

Strand: Direct

Name: malF [H]

Synonym: MXAN_5378

Alternate gene names: 108760888

Gene position: 6697789-6699969 (Clockwise)

Preceding gene: 108763267

Following gene: 108762278

Centisome position: 73.28

GC content: 68.73

Gene sequence:

>2181_bases
GTGAGCCGGTGGCTCGGCCTGGCGCTGCTCGCCACGGCGCTGAGCGCGCACGCGGCGCCTGCGGCGGAGAAGCCGCTGAA
GCTGTGGCACGCGTACCGCGGCGGCGAGGAGATGGCGCTCGTCCAGGCCACGGAGCTCTTCACCTCGAAGACGGGCGTCC
AGGTGGAGCTGCTCGCCCTGCCCTACGACGCCTACGCTGCCAAGCTGACCAACGCCATTCCCCATGGCGTGGGCCCGGAC
GTCTTCATCTTCAACCACGAGCGGCTGCTCAACTTCCACGCGATGCACCTGGTGGCTCCCGCCAGTGGCCTGGCGCGCGA
GGACTACTTCCCCAACGCCGTGGAGGCGCTGGAGGTGGATGGCCAGGTGTACGGCTATCCCATGTCGCTCAAGTCGCTAG
CGCTCTACGTCAATACGAAGCTCGTGCCCCAGCCGCCAGAGACGACGGACGCGCTGCTGGCGATGCTGCCCGCGCTGTCG
GACGCGGACGCGGGCCGCTTCGGGCTGGCCTACGAGAGCGGCGACTTCTACTTCCACGCGGGGTTCCTCTTCGGCTTCGG
CGGCGAGCTGTTCGATGCAAACGGCCGCGCGAGCTTCGACACACAGGGGATGGCCCGTTCCCTGGCCTTTGTGAAGGACC
TGCAGGACCAGCGCTTCATTCCCCAGGAGGCATCGGGCGCGCTGGTGAAGAGCCTCTTCAACGACGGCCGTGCCGCCATG
ATCATCAGCGGGCCGTGGTTCGCTGGGGAGATTGCCCCCCAGGTGGACTACCGCGTGGTGGGGCTGCCGGCGGTGAGCAC
CACGAACATCCCCATCCGCCCCTTCCTGGGCGTGGAGACGGCCTACGTATCCGCGCGCTCCGAGCGAGCGGAGCAGGCCC
AGGCGCTGGCGCGCTTCATCTCCCTGGGCGAGGCCTCTCGCGTGCGAGCCATGGTGGGCCGGCAGATTCCGGCGGACGTG
GCCGCGTACACGCTGAAGGAGGTGCGGGAGGACACGCTCATCTCCTCCTTCCGCGAGGCGGCCCGCCACGCCACGCCCAT
GCCCAACACGCTGGAGATGGCGCGCGTCTGGGAGCCCATGAAGCTGGCGCTGCGCGCGGTGCTCCAGGGCGGCACCGCGC
CCCAGGACGCCGGCGCGCTGGCGGACCGGCGCTACCGCGCGCTGCACCGCGAGCGCCCTCCCGACGCCAGCCCTCTGCCC
TGGCTGGGATTGGTGGGCGCCATGGCGCTGGGCGGCTCCGTCTGGGTCCTGCGGCGCCCGGCGGCGACGCTGCCTTTCAA
GCAGCGGTACCCTGACGTGGCGCAGGCGGTGGCGTACATCACCCCCGCGGCGACTGGCGTGGCGCTGCTGGTGTTCGTCC
CCTTCGCGGTGGGTCTCAGCCTGTCGCTGTTCCACCACGAGGCGGGGGGATACGCCTTCGTGGGCCTGGCCAACTTCGTG
GATATCCTGGCCAGCCGCGGCTACAGCATCACCGAGCCCCTCTCCTTCTATTTCACGCTGGCCGTGACGCTACTGTGGGC
GGTGGTCAACGTGGTGCTCCACGTCAGCATCGGCCTGTTCCTGGCGCTGCTGTTGAAGGATCCGCTGCTGAAGCTGCGGG
GTGTCTACCGGGTGCTGCTCATCATCCCCTGGGCCGTGCCCAACTACATCACCGCGCTCATGTGGAAGGGCATGTTCCAC
CGGCAGTTCGGCGCCATCAACGGCCTGCTGGTCGCCCTGGACCTGGAGCCGGTGAGCTGGTTCACGCGCTTCTCCACAGC
CTTCGCGGCCAACGTGGTCACCAACACCTGGCTGGGGTTTCCCTTCATGATGGTGGTGGCGCTGGGCGCGCTCCAGTCCA
TCCCCCAGGAGCTCTACGAAGCCGCGGAGGTGGACGGCGCGAGCAAGTGGACGCAGTTCCGCCGCATCACCCTGCCGCTG
CTGAGGCCCGCCATGCTGCCCGCCGTCATCTTGGGCAGCGTGTGGACCTTCAACATGTTCAACATCATCTACCTGGTGTC
CGGCGGGGAGCCGGGCGGCGGCACCGACATCCTGGTGTCCGAGGCCTACCGTTGGGCCTTCCAGCGCAACGAGCAGTACG
GCTTCGCGGCGGCGTACTCGGTCCTCATCTTCGTGGTGCTGCTGGTCTGGTCCGCCTTCACCAGGCGATTGATGCGGTCG
TCCTCGGAGGTGATGGGATGA

Upstream 100 bases:

>100_bases
TGCACCTGGCCCCCGTGGCGGACGCGCTGCACGTCTTCTCCAAGGACGGCGCGAAGGCGCTGCGCCATCCGGAGCAGCGC
GCCGCGCTGGAGATCGCGTC

Downstream 100 bases:

>100_bases
ACCGCCCCTCGCGCATGAAGATGGCCGCCATCCACGCCGGACTGACGCTGCTGTGCATGGCCACGCTCTACCCGGTGCTC
TGGGTGGTGAAGATGGCGCT

Product: putative sugar ABC transporter permease/periplasmic sugar-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSRWLGLALLATALSAHAAPAAEKPLKLWHAYRGGEEMALVQATELFTSKTGVQVELLALPYDAYAAKLTNAIPHGVGPD
VFIFNHERLLNFHAMHLVAPASGLAREDYFPNAVEALEVDGQVYGYPMSLKSLALYVNTKLVPQPPETTDALLAMLPALS
DADAGRFGLAYESGDFYFHAGFLFGFGGELFDANGRASFDTQGMARSLAFVKDLQDQRFIPQEASGALVKSLFNDGRAAM
IISGPWFAGEIAPQVDYRVVGLPAVSTTNIPIRPFLGVETAYVSARSERAEQAQALARFISLGEASRVRAMVGRQIPADV
AAYTLKEVREDTLISSFREAARHATPMPNTLEMARVWEPMKLALRAVLQGGTAPQDAGALADRRYRALHRERPPDASPLP
WLGLVGAMALGGSVWVLRRPAATLPFKQRYPDVAQAVAYITPAATGVALLVFVPFAVGLSLSLFHHEAGGYAFVGLANFV
DILASRGYSITEPLSFYFTLAVTLLWAVVNVVLHVSIGLFLALLLKDPLLKLRGVYRVLLIIPWAVPNYITALMWKGMFH
RQFGAINGLLVALDLEPVSWFTRFSTAFAANVVTNTWLGFPFMMVVALGALQSIPQELYEAAEVDGASKWTQFRRITLPL
LRPAMLPAVILGSVWTFNMFNIIYLVSGGEPGGGTDILVSEAYRWAFQRNEQYGFAAAYSVLIFVVLLVWSAFTRRLMRS
SSEVMG

Sequences:

>Translated_726_residues
MSRWLGLALLATALSAHAAPAAEKPLKLWHAYRGGEEMALVQATELFTSKTGVQVELLALPYDAYAAKLTNAIPHGVGPD
VFIFNHERLLNFHAMHLVAPASGLAREDYFPNAVEALEVDGQVYGYPMSLKSLALYVNTKLVPQPPETTDALLAMLPALS
DADAGRFGLAYESGDFYFHAGFLFGFGGELFDANGRASFDTQGMARSLAFVKDLQDQRFIPQEASGALVKSLFNDGRAAM
IISGPWFAGEIAPQVDYRVVGLPAVSTTNIPIRPFLGVETAYVSARSERAEQAQALARFISLGEASRVRAMVGRQIPADV
AAYTLKEVREDTLISSFREAARHATPMPNTLEMARVWEPMKLALRAVLQGGTAPQDAGALADRRYRALHRERPPDASPLP
WLGLVGAMALGGSVWVLRRPAATLPFKQRYPDVAQAVAYITPAATGVALLVFVPFAVGLSLSLFHHEAGGYAFVGLANFV
DILASRGYSITEPLSFYFTLAVTLLWAVVNVVLHVSIGLFLALLLKDPLLKLRGVYRVLLIIPWAVPNYITALMWKGMFH
RQFGAINGLLVALDLEPVSWFTRFSTAFAANVVTNTWLGFPFMMVVALGALQSIPQELYEAAEVDGASKWTQFRRITLPL
LRPAMLPAVILGSVWTFNMFNIIYLVSGGEPGGGTDILVSEAYRWAFQRNEQYGFAAAYSVLIFVVLLVWSAFTRRLMRS
SSEVMG
>Mature_725_residues
SRWLGLALLATALSAHAAPAAEKPLKLWHAYRGGEEMALVQATELFTSKTGVQVELLALPYDAYAAKLTNAIPHGVGPDV
FIFNHERLLNFHAMHLVAPASGLAREDYFPNAVEALEVDGQVYGYPMSLKSLALYVNTKLVPQPPETTDALLAMLPALSD
ADAGRFGLAYESGDFYFHAGFLFGFGGELFDANGRASFDTQGMARSLAFVKDLQDQRFIPQEASGALVKSLFNDGRAAMI
ISGPWFAGEIAPQVDYRVVGLPAVSTTNIPIRPFLGVETAYVSARSERAEQAQALARFISLGEASRVRAMVGRQIPADVA
AYTLKEVREDTLISSFREAARHATPMPNTLEMARVWEPMKLALRAVLQGGTAPQDAGALADRRYRALHRERPPDASPLPW
LGLVGAMALGGSVWVLRRPAATLPFKQRYPDVAQAVAYITPAATGVALLVFVPFAVGLSLSLFHHEAGGYAFVGLANFVD
ILASRGYSITEPLSFYFTLAVTLLWAVVNVVLHVSIGLFLALLLKDPLLKLRGVYRVLLIIPWAVPNYITALMWKGMFHR
QFGAINGLLVALDLEPVSWFTRFSTAFAANVVTNTWLGFPFMMVVALGALQSIPQELYEAAEVDGASKWTQFRRITLPLL
RPAMLPAVILGSVWTFNMFNIIYLVSGGEPGGGTDILVSEAYRWAFQRNEQYGFAAAYSVLIFVVLLVWSAFTRRLMRSS
SEVMG

Specific function: Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side. Note=A substantial portion of it protrudes into the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=244, Percent_Identity=38.5245901639344, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI1787570, Length=248, Percent_Identity=32.6612903225806, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790466, Length=410, Percent_Identity=26.5853658536585, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 79302; Mature: 79171

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRWLGLALLATALSAHAAPAAEKPLKLWHAYRGGEEMALVQATELFTSKTGVQVELLAL
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEEEEE
PYDAYAAKLTNAIPHGVGPDVFIFNHERLLNFHAMHLVAPASGLAREDYFPNAVEALEVD
CCHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCC
GQVYGYPMSLKSLALYVNTKLVPQPPETTDALLAMLPALSDADAGRFGLAYESGDFYFHA
CEEEECCCCHHHEEEEEECEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEE
GFLFGFGGELFDANGRASFDTQGMARSLAFVKDLQDQRFIPQEASGALVKSLFNDGRAAM
EEHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEE
IISGPWFAGEIAPQVDYRVVGLPAVSTTNIPIRPFLGVETAYVSARSERAEQAQALARFI
EEECCCCCCCCCCCCCEEEEECCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLGEASRVRAMVGRQIPADVAAYTLKEVREDTLISSFREAARHATPMPNTLEMARVWEPM
HCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KLALRAVLQGGTAPQDAGALADRRYRALHRERPPDASPLPWLGLVGAMALGGSVWVLRRP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
AATLPFKQRYPDVAQAVAYITPAATGVALLVFVPFAVGLSLSLFHHEAGGYAFVGLANFV
CCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHH
DILASRGYSITEPLSFYFTLAVTLLWAVVNVVLHVSIGLFLALLLKDPLLKLRGVYRVLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IIPWAVPNYITALMWKGMFHRQFGAINGLLVALDLEPVSWFTRFSTAFAANVVTNTWLGF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
PFMMVVALGALQSIPQELYEAAEVDGASKWTQFRRITLPLLRPAMLPAVILGSVWTFNMF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
NIIYLVSGGEPGGGTDILVSEAYRWAFQRNEQYGFAAAYSVLIFVVLLVWSAFTRRLMRS
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSEVMG
HHHCCC
>Mature Secondary Structure 
SRWLGLALLATALSAHAAPAAEKPLKLWHAYRGGEEMALVQATELFTSKTGVQVELLAL
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEEEEE
PYDAYAAKLTNAIPHGVGPDVFIFNHERLLNFHAMHLVAPASGLAREDYFPNAVEALEVD
CCHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCC
GQVYGYPMSLKSLALYVNTKLVPQPPETTDALLAMLPALSDADAGRFGLAYESGDFYFHA
CEEEECCCCHHHEEEEEECEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEE
GFLFGFGGELFDANGRASFDTQGMARSLAFVKDLQDQRFIPQEASGALVKSLFNDGRAAM
EEHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEE
IISGPWFAGEIAPQVDYRVVGLPAVSTTNIPIRPFLGVETAYVSARSERAEQAQALARFI
EEECCCCCCCCCCCCCEEEEECCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLGEASRVRAMVGRQIPADVAAYTLKEVREDTLISSFREAARHATPMPNTLEMARVWEPM
HCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KLALRAVLQGGTAPQDAGALADRRYRALHRERPPDASPLPWLGLVGAMALGGSVWVLRRP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
AATLPFKQRYPDVAQAVAYITPAATGVALLVFVPFAVGLSLSLFHHEAGGYAFVGLANFV
CCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHH
DILASRGYSITEPLSFYFTLAVTLLWAVVNVVLHVSIGLFLALLLKDPLLKLRGVYRVLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IIPWAVPNYITALMWKGMFHRQFGAINGLLVALDLEPVSWFTRFSTAFAANVVTNTWLGF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
PFMMVVALGALQSIPQELYEAAEVDGASKWTQFRRITLPLLRPAMLPAVILGSVWTFNMF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
NIIYLVSGGEPGGGTDILVSEAYRWAFQRNEQYGFAAAYSVLIFVVLLVWSAFTRRLMRS
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSEVMG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2674653 [H]