Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 108760871

GI number: 108760871

Start: 2291813

End: 2292775

Strand: Direct

Name: trxB [H]

Synonym: MXAN_1954

Alternate gene names: 108760871

Gene position: 2291813-2292775 (Clockwise)

Preceding gene: 108759979

Following gene: 108758343

Centisome position: 25.08

GC content: 67.39

Gene sequence:

>963_bases
GTGGCGGAGGAGAAGATCAACAAGGTGACCATCATCGGCTCGGGGCCCGCGGGCTACACCGCGGCCATCTACGCCGCGCG
CGCCAACCTGCAGCCGGTGGTGTTCGCCGGGGGCCCCACCCTGGAGCACCCGCAGCGGGTGCCGGGCGGCCAGCTCATGG
TGACCACCGACGTGGAGAACTACCCGGGCTTTCCGGAGGCCATCACCGGCCCGGAGCTGATGGATCGCTTCCAGAAGCAG
GCAGAGCGTTTCGGCACCACCATCCACATGGAGAACGTGGTGAAGGTGGACTTCTCCCAGCGCCCCTTCCTCATCCAGGG
GGAGAGCGTCAGCTGCCGCTCGGAGACGGTCATCATCTCCACCGGCGCTACCGCCAAGTGGCTGGGCGTCAAGGGCGAGG
ACACCTACAAGAACCGCGGCGTCTCCGCGTGCGCCACCTGCGACGGTGCCTTCTTCAAGAAGCAGGACGTGCTGGTGGTG
GGCGGCGGTGACACGGCGATGGAGGAGGCGACGTACCTGGCGAAAATCGTCAACCACGTCACCCTCATCCACCGCCGCGA
CACGCTGCGCGCCTCCAAGGTGATGCAGGAGCGCGCCCGCCAGAATCCGAAAATCTCCTTCATGTGGGACTCCGCGGTGG
AGGAGGTCCTCGGCGACGCGAAGGGGATGAATGGCGCGGTGGTGCGCAACCTGAAGACGGGTGACAGCCAGCAGGTGAAG
GCGACCGGCCTGTTCGTGGCCATTGGCCACACGCCCAACACGGAGCTGTTCCAGGGCGTGCTGGAGACGCACCAGGGCGG
CTACCTCAAGACGGTGCCGGGCTCCACGCGCACCAACATCGAGGGCGTGTTCGCCTGCGGTGACGTGCAGGACCACTACT
ACCGCCAGGCCATCACCGCGGCGGGCACGGGCTGCATGGCCGCCATCGACGCGGAGCGCTGGCTCATCGAGCACGGCGAG
TAG

Upstream 100 bases:

>100_bases
CAACCTTCTTGAGGACTGCGGCATCCATGAGGCCAGCTTCGTATCACGCGCCCGAGGCGCTCTGGTACCTTGGGGCCATC
AACGAGATTTGGGAGGAGTC

Downstream 100 bases:

>100_bases
TCCACCCGCTCGCGCGGCTCCGCTGAGCATTCCCAGGCCGGCCCCTTCCCGGGGCCGGCCTTTCCATTCCCGCGAAGGAC
GCAGCAATCCCCATGAGCTC

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAEEKINKVTIIGSGPAGYTAAIYAARANLQPVVFAGGPTLEHPQRVPGGQLMVTTDVENYPGFPEAITGPELMDRFQKQ
AERFGTTIHMENVVKVDFSQRPFLIQGESVSCRSETVIISTGATAKWLGVKGEDTYKNRGVSACATCDGAFFKKQDVLVV
GGGDTAMEEATYLAKIVNHVTLIHRRDTLRASKVMQERARQNPKISFMWDSAVEEVLGDAKGMNGAVVRNLKTGDSQQVK
ATGLFVAIGHTPNTELFQGVLETHQGGYLKTVPGSTRTNIEGVFACGDVQDHYYRQAITAAGTGCMAAIDAERWLIEHGE

Sequences:

>Translated_320_residues
MAEEKINKVTIIGSGPAGYTAAIYAARANLQPVVFAGGPTLEHPQRVPGGQLMVTTDVENYPGFPEAITGPELMDRFQKQ
AERFGTTIHMENVVKVDFSQRPFLIQGESVSCRSETVIISTGATAKWLGVKGEDTYKNRGVSACATCDGAFFKKQDVLVV
GGGDTAMEEATYLAKIVNHVTLIHRRDTLRASKVMQERARQNPKISFMWDSAVEEVLGDAKGMNGAVVRNLKTGDSQQVK
ATGLFVAIGHTPNTELFQGVLETHQGGYLKTVPGSTRTNIEGVFACGDVQDHYYRQAITAAGTGCMAAIDAERWLIEHGE
>Mature_319_residues
AEEKINKVTIIGSGPAGYTAAIYAARANLQPVVFAGGPTLEHPQRVPGGQLMVTTDVENYPGFPEAITGPELMDRFQKQA
ERFGTTIHMENVVKVDFSQRPFLIQGESVSCRSETVIISTGATAKWLGVKGEDTYKNRGVSACATCDGAFFKKQDVLVVG
GGDTAMEEATYLAKIVNHVTLIHRRDTLRASKVMQERARQNPKISFMWDSAVEEVLGDAKGMNGAVVRNLKTGDSQQVKA
TGLFVAIGHTPNTELFQGVLETHQGGYLKTVPGSTRTNIEGVFACGDVQDHYYRQAITAAGTGCMAAIDAERWLIEHGE

Specific function: Component of the thioredoxin-thioredoxin reductase system which may be involved in biosynthesis of penicillins and cephalosporins and may be important in determining the thiol- disulfide redox balance [H]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=323, Percent_Identity=50.4643962848297, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI87081763, Length=332, Percent_Identity=33.433734939759, Blast_Score=151, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=48.2539682539683, Blast_Score=313, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=46.6666666666667, Blast_Score=303, Evalue=3e-83,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34626; Mature: 34494

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEKINKVTIIGSGPAGYTAAIYAARANLQPVVFAGGPTLEHPQRVPGGQLMVTTDVEN
CCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCC
YPGFPEAITGPELMDRFQKQAERFGTTIHMENVVKVDFSQRPFLIQGESVSCRSETVIIS
CCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCEEEECCCCCCCCCEEEEE
TGATAKWLGVKGEDTYKNRGVSACATCDGAFFKKQDVLVVGGGDTAMEEATYLAKIVNHV
CCCCEEEEECCCCCCHHHCCCEEEEECCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHH
TLIHRRDTLRASKVMQERARQNPKISFMWDSAVEEVLGDAKGMNGAVVRNLKTGDSQQVK
HEEECHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCEEEEECCCCCCEEE
ATGLFVAIGHTPNTELFQGVLETHQGGYLKTVPGSTRTNIEGVFACGDVQDHYYRQAITA
EEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHH
AGTGCMAAIDAERWLIEHGE
CCCCEEEEECHHHHEEECCC
>Mature Secondary Structure 
AEEKINKVTIIGSGPAGYTAAIYAARANLQPVVFAGGPTLEHPQRVPGGQLMVTTDVEN
CCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCC
YPGFPEAITGPELMDRFQKQAERFGTTIHMENVVKVDFSQRPFLIQGESVSCRSETVIIS
CCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCEEEECCCCCCCCCEEEEE
TGATAKWLGVKGEDTYKNRGVSACATCDGAFFKKQDVLVVGGGDTAMEEATYLAKIVNHV
CCCCEEEEECCCCCCHHHCCCEEEEECCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHH
TLIHRRDTLRASKVMQERARQNPKISFMWDSAVEEVLGDAKGMNGAVVRNLKTGDSQQVK
HEEECHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCEEEEECCCCCCEEE
ATGLFVAIGHTPNTELFQGVLETHQGGYLKTVPGSTRTNIEGVFACGDVQDHYYRQAITA
EEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHH
AGTGCMAAIDAERWLIEHGE
CCCCEEEEECHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349555; 8423136 [H]