Click here to switch to the map view.

The map label for this gene is dnaK [H]

Identifier: 108760854

GI number: 108760854

Start: 6624897

End: 6626759

Strand: Direct

Name: dnaK [H]

Synonym: MXAN_5322

Alternate gene names: 108760854

Gene position: 6624897-6626759 (Clockwise)

Preceding gene: 108757166

Following gene: 108763729

Centisome position: 72.48

GC content: 72.09

Gene sequence:

>1863_bases
ATGGCCCGCTATTCCATTGGCATCGACCTGGGCACTACGCACTCCGCAGCGTCCTACTTCAATCTGGAGGAGGGCAAGCC
CCGCGGCGGCGCGCAGTCCATGCTGCCCGTCCCCCAGTTGACCGCGCCCGGCACCGTCGAGGCCCGCCCGCTGCTCCCCT
CCTTCCTCTATCTCCCCTCCGAGCAGGAGTTCCCCGCCGGCAGCCTGGCGCTGCCGTGGAAGCCGGAGGCCAGCACCCTG
ATGGGTGAGTTCGCCCGCACGCACGGCGCCAAGGTGCCCACGCGGCTGGTGGCCTCCGCCAAGAGCTGGCTGTCCCACCC
CGGCGTGGACCGGCGCGCGGCGCTGCTGCCGTGGCAGGCCCCCGAGGAGGTGCAACGGGTGTCGCCGCTAGACGCCTCCG
CGCGCTACCTCCGCCACCTCAAGGACGCGTGGGACCACACCTTCGCCCGCGAGCGCGAGGAGTCCGACAACGCCCTGGCC
GAACAGGACGTCATCATCACCGTCCCCGCCTCCTTCGACGCGGCGGCGCGCGACCTGACGCTGGAGGCCGCCAAGGCCGC
GGGCATCCCCAACATCACCCTGCTGGAGGAGCCCCAGGCCGCGCTCTACGCGTGGCTGGAGGCCATGGGGGAGAACTTCC
GCAAGCAGGTGCAGCCCGGCGCGGTCATCCTCGTGGTGGACGTGGGCGGCGGCACCTCCGACTTCTCCGTCATCACCGTG
CGCGACAACGCCGGTGACCTGGAGCTGCTCCGCGTGGCCGTGGGCGACCACATCCTGCTGGGCGGCGACAACATGGACCT
GGCGCTGGCGCACACGCTGAACCAGCGCATGGCGGCCGAGGGCAAGAAGCTGGACGCCTGGCAATTCAACGCCCTCACCC
ATGGCTGCCGCCAGGCGAAGGAGGCGCTCTACGCCGACCCGTCCATGGAGCGCGCACCCATCTCCATCCCCGGCCGGGGG
TCGTCGCTCATCGGCGGCACGCTGCGCACGGAGCTGACGCGCGAGGAGCTGGACCGCGTCCTCACCGACGGCTTCTTCCC
CGTGACGCCCGTCACCGAGCTGCCGCGCACCGCGCGCCGCACCGGCCTGGCGCAGATGGCGCTGCCCTACGCCCAGGACG
CCGGGGTATCCCGTCACCTGGCCGCCTTCCTCACCCGGCAGGCGCAGGCGCTCGCGTCCAGCCCGGACGCGCCGGTGGAC
GTCAGCGGCAAGGCCTTCCTCCACCCCACGGCGGTGCTCTTCAACGGCGGCGTCTTCAAGGCCGGCCCGCTGAAGGCGCG
CGTCATGGAGGTGATCAACGGCTGGCTCACGGCGGATGGCGGAGCGCCCGCCGAGGCGCTGGAGGGCGCGGACCTGGACC
TCGCGGTGGCGCGCGGCGCCGCCTATTATGGTTGGGTGCGCCAGGGCCACGGCCTGCGCATCCGCGGCGGCACGGCCCGC
GCCTACTACGTGGGCGTGGAGACGGCGATGCCCGCGGTGCCCGGCATGGAGCCGCCCGTGAAGGCGCTCTGCGTGGCCCC
CTTCGGCATGGAGGAAGGCACGCAGGCGGACGTCCCGCCCCAGGAGTTCGGGCTCGTCACCGGTGAGCCCACCCGCTTCC
GCTTCTTCTCCTCTTCCCTGCGGCGCGACGACAAGGTGGGCGTCATGCTGGAGGACGTCGACACCGAGCTGGCCAGCGGC
GGGCTGGAGGAGCTGGCTCCCATCGAGACGACCATGCCCGGTCAGCCCTCCGTCTTCAGCGACCTGACGCCCGTCAACCT
CCAGGCGGCGGTGACGGAGGTGGGGACGCTGGAGCTCCGGTGCCTGGAGAAGGATGGCCCCGGGCGCTGGAAGCTGGAAC
TCAACGTCCGCATGAAGGAGTAG

Upstream 100 bases:

>100_bases
CCGCGCGTGCTTGCTCCCGCGGAGGTCGAGCTTTCCTGAGCCGGCCACCACGACCTCACAGCGCGAACAAACCCGCGTCT
TCCAGGAGTTCTCGTCCGAT

Downstream 100 bases:

>100_bases
AAAGCCATCCGTCAATCGGAGGCGTATGCGAATCGTTGGCATCGACCTGGGCACCACCCATTGCGCCGTGGCATCCGTGG
ACCCCTCGCGGGGCGCGGGT

Product: heat shock protein 70 family protein

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MARYSIGIDLGTTHSAASYFNLEEGKPRGGAQSMLPVPQLTAPGTVEARPLLPSFLYLPSEQEFPAGSLALPWKPEASTL
MGEFARTHGAKVPTRLVASAKSWLSHPGVDRRAALLPWQAPEEVQRVSPLDASARYLRHLKDAWDHTFAREREESDNALA
EQDVIITVPASFDAAARDLTLEAAKAAGIPNITLLEEPQAALYAWLEAMGENFRKQVQPGAVILVVDVGGGTSDFSVITV
RDNAGDLELLRVAVGDHILLGGDNMDLALAHTLNQRMAAEGKKLDAWQFNALTHGCRQAKEALYADPSMERAPISIPGRG
SSLIGGTLRTELTREELDRVLTDGFFPVTPVTELPRTARRTGLAQMALPYAQDAGVSRHLAAFLTRQAQALASSPDAPVD
VSGKAFLHPTAVLFNGGVFKAGPLKARVMEVINGWLTADGGAPAEALEGADLDLAVARGAAYYGWVRQGHGLRIRGGTAR
AYYVGVETAMPAVPGMEPPVKALCVAPFGMEEGTQADVPPQEFGLVTGEPTRFRFFSSSLRRDDKVGVMLEDVDTELASG
GLEELAPIETTMPGQPSVFSDLTPVNLQAAVTEVGTLELRCLEKDGPGRWKLELNVRMKE

Sequences:

>Translated_620_residues
MARYSIGIDLGTTHSAASYFNLEEGKPRGGAQSMLPVPQLTAPGTVEARPLLPSFLYLPSEQEFPAGSLALPWKPEASTL
MGEFARTHGAKVPTRLVASAKSWLSHPGVDRRAALLPWQAPEEVQRVSPLDASARYLRHLKDAWDHTFAREREESDNALA
EQDVIITVPASFDAAARDLTLEAAKAAGIPNITLLEEPQAALYAWLEAMGENFRKQVQPGAVILVVDVGGGTSDFSVITV
RDNAGDLELLRVAVGDHILLGGDNMDLALAHTLNQRMAAEGKKLDAWQFNALTHGCRQAKEALYADPSMERAPISIPGRG
SSLIGGTLRTELTREELDRVLTDGFFPVTPVTELPRTARRTGLAQMALPYAQDAGVSRHLAAFLTRQAQALASSPDAPVD
VSGKAFLHPTAVLFNGGVFKAGPLKARVMEVINGWLTADGGAPAEALEGADLDLAVARGAAYYGWVRQGHGLRIRGGTAR
AYYVGVETAMPAVPGMEPPVKALCVAPFGMEEGTQADVPPQEFGLVTGEPTRFRFFSSSLRRDDKVGVMLEDVDTELASG
GLEELAPIETTMPGQPSVFSDLTPVNLQAAVTEVGTLELRCLEKDGPGRWKLELNVRMKE
>Mature_619_residues
ARYSIGIDLGTTHSAASYFNLEEGKPRGGAQSMLPVPQLTAPGTVEARPLLPSFLYLPSEQEFPAGSLALPWKPEASTLM
GEFARTHGAKVPTRLVASAKSWLSHPGVDRRAALLPWQAPEEVQRVSPLDASARYLRHLKDAWDHTFAREREESDNALAE
QDVIITVPASFDAAARDLTLEAAKAAGIPNITLLEEPQAALYAWLEAMGENFRKQVQPGAVILVVDVGGGTSDFSVITVR
DNAGDLELLRVAVGDHILLGGDNMDLALAHTLNQRMAAEGKKLDAWQFNALTHGCRQAKEALYADPSMERAPISIPGRGS
SLIGGTLRTELTREELDRVLTDGFFPVTPVTELPRTARRTGLAQMALPYAQDAGVSRHLAAFLTRQAQALASSPDAPVDV
SGKAFLHPTAVLFNGGVFKAGPLKARVMEVINGWLTADGGAPAEALEGADLDLAVARGAAYYGWVRQGHGLRIRGGTARA
YYVGVETAMPAVPGMEPPVKALCVAPFGMEEGTQADVPPQEFGLVTGEPTRFRFFSSSLRRDDKVGVMLEDVDTELASGG
LEELAPIETTMPGQPSVFSDLTPVNLQAAVTEVGTLELRCLEKDGPGRWKLELNVRMKE

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI1788875, Length=277, Percent_Identity=29.6028880866426, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534015, Length=379, Percent_Identity=24.5382585751979, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17534013, Length=379, Percent_Identity=24.5382585751979, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17507981, Length=362, Percent_Identity=24.3093922651934, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320950, Length=361, Percent_Identity=22.9916897506925, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323004, Length=377, Percent_Identity=23.342175066313, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319314, Length=377, Percent_Identity=24.1379310344828, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647515, Length=370, Percent_Identity=25.4054054054054, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24663992, Length=202, Percent_Identity=30.6930693069307, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24663988, Length=202, Percent_Identity=30.6930693069307, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 66561; Mature: 66430

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00297 HSP70_1 ; PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYSIGIDLGTTHSAASYFNLEEGKPRGGAQSMLPVPQLTAPGTVEARPLLPSFLYLPS
CCEEEEEEECCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCC
EQEFPAGSLALPWKPEASTLMGEFARTHGAKVPTRLVASAKSWLSHPGVDRRAALLPWQA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCC
PEEVQRVSPLDASARYLRHLKDAWDHTFAREREESDNALAEQDVIITVPASFDAAARDLT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHH
LEAAKAAGIPNITLLEEPQAALYAWLEAMGENFRKQVQPGAVILVVDVGGGTSDFSVITV
HHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEE
RDNAGDLELLRVAVGDHILLGGDNMDLALAHTLNQRMAAEGKKLDAWQFNALTHGCRQAK
ECCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
EALYADPSMERAPISIPGRGSSLIGGTLRTELTREELDRVLTDGFFPVTPVTELPRTARR
HHHCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHH
TGLAQMALPYAQDAGVSRHLAAFLTRQAQALASSPDAPVDVSGKAFLHPTAVLFNGGVFK
HCHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEECCEEEEECCCEEC
AGPLKARVMEVINGWLTADGGAPAEALEGADLDLAVARGAAYYGWVRQGHGLRIRGGTAR
CCCHHHHHHHHHHCEEECCCCCCHHHHCCCCCEEEECCCCHHHHHHCCCCCEEEECCCCE
AYYVGVETAMPAVPGMEPPVKALCVAPFGMEEGTQADVPPQEFGLVTGEPTRFRFFSSSL
EEEEEHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHH
RRDDKVGVMLEDVDTELASGGLEELAPIETTMPGQPSVFSDLTPVNLQAAVTEVGTLELR
CCCCCCCEEEEHHHHHHHCCCHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHCCEEEEE
CLEKDGPGRWKLELNVRMKE
EEECCCCCEEEEEEEEEECC
>Mature Secondary Structure 
ARYSIGIDLGTTHSAASYFNLEEGKPRGGAQSMLPVPQLTAPGTVEARPLLPSFLYLPS
CEEEEEEECCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCC
EQEFPAGSLALPWKPEASTLMGEFARTHGAKVPTRLVASAKSWLSHPGVDRRAALLPWQA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCC
PEEVQRVSPLDASARYLRHLKDAWDHTFAREREESDNALAEQDVIITVPASFDAAARDLT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHH
LEAAKAAGIPNITLLEEPQAALYAWLEAMGENFRKQVQPGAVILVVDVGGGTSDFSVITV
HHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEE
RDNAGDLELLRVAVGDHILLGGDNMDLALAHTLNQRMAAEGKKLDAWQFNALTHGCRQAK
ECCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
EALYADPSMERAPISIPGRGSSLIGGTLRTELTREELDRVLTDGFFPVTPVTELPRTARR
HHHCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHH
TGLAQMALPYAQDAGVSRHLAAFLTRQAQALASSPDAPVDVSGKAFLHPTAVLFNGGVFK
HCHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEECCEEEEECCCEEC
AGPLKARVMEVINGWLTADGGAPAEALEGADLDLAVARGAAYYGWVRQGHGLRIRGGTAR
CCCHHHHHHHHHHCEEECCCCCCHHHHCCCCCEEEECCCCHHHHHHCCCCCEEEECCCCE
AYYVGVETAMPAVPGMEPPVKALCVAPFGMEEGTQADVPPQEFGLVTGEPTRFRFFSSSL
EEEEEHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHH
RRDDKVGVMLEDVDTELASGGLEELAPIETTMPGQPSVFSDLTPVNLQAAVTEVGTLELR
CCCCCCCEEEEHHHHHHHCCCHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHCCEEEEE
CLEKDGPGRWKLELNVRMKE
EEECCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12835416 [H]