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The map label for this gene is lgrD [H]

Identifier: 108760771

GI number: 108760771

Start: 5647084

End: 5653548

Strand: Reverse

Name: lgrD [H]

Synonym: MXAN_4532

Alternate gene names: 108760771

Gene position: 5653548-5647084 (Counterclockwise)

Preceding gene: 108764002

Following gene: 108760644

Centisome position: 61.86

GC content: 71.55

Gene sequence:

>6465_bases
ATGACCGAGCACATCGAGCCGCGAGCTCACCGTTTCCCCACCCTGGTGGACGTGTTGTGTCAACGCGCCGAGTCTCAAGG
CGACGCGCTGTTGTATCGCTTCCTGGAGACGGGAGACGTGGACGGCCCGGTGGAGGAGTGGACCTACCGGCGGCTGGATT
CACGGGCGCGGTCGCTGGGGGCTCGGCTGCGTGCCCTGGGGGCGCAGGGGGAGCGGGCGCTGCTGCTCTATCCGCCCGGC
CTGGAGTTCGTCGCGGGCTTCATGGGCTGTCTGTATGGCGGCGTCATCGCCGTGCCGTGTTACCCGCCGGACCCCACGCG
GTTGGAGCGCACGCTGCCGCGCCTTCGCGCCATCGCCCGGGACTGCGGCGCGCGCTACGTGCTGACGACGAGCACCATCC
AGGAGATGGCGGAGTTCCTCACGCCACAGGCTCCCGAGCTGGGTGAATTGCAGTGGATTGCCAGTGACGCGGTGCCGGAA
GCCGAGGCCGCGGACTGGAAGCGCCCGGACCTGACGTCCGAGTCGCTGGCCTTCTTGCAATACACGTCGGGTTCCACGGG
CAACCCGAAGGGGGTCAAGGTCAGCCACGCCAACATCCTCCACAACGAGTCGTTGATTACGCGTGACTTCGGGTTGCAGG
CGGAGCGTTCGGTGGGCGTGGGCTGGTTGCCCATGTTCCATGACATGGGGCTCATCGGTAAGGTGTTGCAGCCGCTCTAC
CTGGGCTTCCCGTGCGTGCTGATGTCGCCCATCGCGTTCCTTCAGCGGCCCTTGCGTTGGCTGGAGGCCGTCTCCCATTT
CAAGGGGACGGTCAGTGGTGGACCCAACTTCGCGTACGACCTGTGCGCGCGAAAGGCCCGCGCCGAAGACGTGGCCCGTC
TGGATTTGAGCCACTGGGACCTGGCCTTCAACGGCGCGGAGCCCGTGCGGCGCGAGACGATGGAGCGCTTCGCGGAGACG
TTCGCGCCCGCTGGCTTCCGGCGCGAGGCCTTCTATCCCTGCTACGGCCTGGCAGAGGCGACGCTCATCGTCAGCGGCGG
CGTGAAGGGAACGCCTTGTGTGCAGGAGCGCTACGACACCGGCTCGCTGGAGCTGGGGCGCGCGAAGCCCGCGTCCGACG
CGGCGGAGGGGCCCACGGCGCGCACGCTGGTGTCCTCCGGTCAGGGCGCGCCGGACCAGCGGCTGCTCATCGTGGACCCG
GAGACGCGGGTGCCTCGGGCCTCGAACGAGGTGGGTGAGGTCTGGGTCGCTGGCCCCAGCGTGGCGGGTGGGTATTGGGA
TCGTCCGGAGGAGACGGCGCATGCCTTCGGCGCGCGGCTCGCCAACGGCGAGGGGCCCTTCCTCCGCACCGGTGACCTGG
CTTTCCTGTCGCCGGAGGGCGAGCTCTTCATCACCGGCCGTCTCAAGGATCTGCTCATCGTCCGGGGTCGGAACCTGTAT
CCGCAGGACCTGGAAATGACCGCGGAGCGCGCGCACCGCGCGGTGCGTCCCGGCTGCAGCGCCGCCTTCTCCGTGGACGT
GGAGGGGGAGGAGCGGCTGGTGGTGGTCTCCGAGGTCGACGTGCGCGAAGGCTTCGACGGCGCGGCGGTGGTGGGCGCCC
TGCGCCGCGCGCTCGCCGATGAGCACCAGGTGCATGCGCACACGGTGGTGCTGCTCCAGGCCCGGAGCATTCCGAAGACA
TCGAGCGGGAAGATTCAGCGCCGCGCCTGTCGTGATGGCTTCCTGGCGGGCTCGCTGGAGGTGGTGGAGGTGTCGGGCGA
GGAGGCCGCTCCGGTGCCGGAGGCCGTGCCTTCCACGCCGTCCGCGCCCCTGCGCGAGCGCCTGGCCCTGGCGTCCGAGG
AGGCCCGTCCGGCGCTGCTGGTGGACTTCCTCCGCGTGGAGGCCGCGCGGGTGCTGCGCGCTGCGCCCGCGTCCCTGGCG
CCGGAGACGTCGCTGGCCAGCCTGGGGCTCGACTCGCTGATGGCGCTGGAGCTCCACGGCCGGCTGGAAGAGGAACTCGG
TGTGTCGCTGCCCGTGGCCTTCCTCTGGCAGCACCCGACGCTGGGGACCGCCGCCGCGCATCTGGTGGACGCGTGGAAGG
GCTCCGCCGCGCCCGCCGCGCCGCCGCTGAAGGCCGGCTCGCTGGAGGGAGAGCTGCCGCTGTCTCCCGGTCAGCAGCGC
CTGTGGTTCCTGGACCGGCTGGTGCCGGAGAGCGCGCTGTACAACGTCCACTTCCAGCTCCGGCTCTCCGGCGCGCTGGA
CGTGCCCGCGCTGGAGCGCGCGCTGCAAGGGCTCCTGTCGCGTCACGCGGTGCTGCGCGCGGCCTTCCCCGAAGTGGAGG
GTCAGCCGCGCCAGCTCCTGCCGCCCCTGCGTCCGCTGGACGTGGCCCGCGAGGACCTGCGGGCGCTGTCGCCCGCCGAG
CGTGACGCGCGGCTGAATCAGTTGGCCCGCGCCCAGGGCGAGGCGCCCTTCAATCTCTCAGAGGGCCTGCTGGTGCGTGC
GGCGCTGGTGGCGCTGGAGGACCAGGAGCACGTGCTCCTGATGACCCAGCACCACATCGTCACCGATGGCTGGTCCATTG
GCGTCCTGGCCCGGGAGCTGGCCGCGCTGTACCGCGCGGAGGTGGCTGGCGCCGCCGCGTCGCTGGGCGCGCCCGCCTTG
CAGTACGTGGACTACGCACGTTGGCAGCGCGGGCTGGGCGGCGCGCTGGACGGGCAGCGTGCCTACTGGGCGCGGAAGCT
GGAGAACCTGCCGCGCCTGGAGTTGCCCACGGACTTCCCGCGTCCCCGGGAGCCGGGCTTCCGCGGCGCGCTCCACCGTT
TCGCGCTGCCGGCCGAGCTGGTGGATTCGCTCAAGGCGGTGGGCCGGAGTGAGGGCTGTACCTTCTTCGTTACGCTGGCG
GCGGCCTGGGCGGCGCTGCTGCACCGCTATAGCGGTCAGGACGACTTCGGCCTGGGCACCATCTTCGCGCAGCGGGACCG
GGCCGAGCTGCGTGACGTGGTGGGGTTCTTCGCCAGCACGCTGGTGCTCCGCGCGGACGTGTCCGGCGCGCCCCGCTTCC
GGGAGCTGCTGGGCCGCATGCGCCACACGTTCCACGAGGCCCTGGCGCACGCGGACCTGCCCTTCGAGGAAGTGGTGGGC
GCGTCGCGCGCGGTCCGTGGCGGCGACAACCCGCTGTTCCAGGCGAACCTGGTGTTGGAGAGCCTGCCGCCGGTGGACAT
GGACGTGCCGGGCATGCAGTGGCGCCCGGTGCTGCCCGTGCCGGACGGCGCGGTGGAGGGCACGGCGAAGTTCGACCTGC
AGCTCGCCGTCGTGGAGACGCCGCGAGGGCTGGAGGGCGCGCTGGAGTACCGCTCGGACCTCTTCTCGGCGGAGACGATG
GCGCGGCTCGCGGGACACCTGGAGGCGTTGCTGAGGGGCATCGTCGCTGCTCCGGACGCGCGTGTGGAGGACCTGCCGCT
GCTCGACGAGGCGGAGCGTCGTTCTCTGCTGGAGCGCTGGAACGACTTCACGGCGCCGCTCTCCCAGGACGCTTCGCACT
GCATCCACGCGCAGTTCCGTGAGCAGGCCGCCCGCACGCCCGACGCGGTGGCGGTGGTCGCCGAGGACGGGACGCTCACC
TACGCGGAGCTGGCGCGCCGTGCGTCCGCGCTGGCCTTGCATCTGAGGGGCCTGGGCGTGGGCCCCGAGGTGCGCGTGGG
CCTGTGCGCCGAGCGCTCGGTGGAGATGGTGGCGGGGATGCTCGGCATCCTCGAGGCGGGCGGCGCCTACGTGCCCCTGG
ACCCGGACTATCCCCGGGAGCGGCTCACGTACATGCTGGAGGACTCGGGCGCGCGCGTGCTCGTCACGCAGTCCCATCTG
GCGGGGACGCTGCCCGTGGCCGGCCTGCACACCGTGCTGCTGGATACGGCGGAGCCCTACGCGGCGATGCCGGCGTCACC
GCTGGCCCTGGGGACCACGCCGGACAACGCGGCGTATGTCATCTACACGTCGGGCTCCACGGGACGGCCCAAGGGCGTGG
TGGTACCGCATGGGGGCGTGGCCAACTTCTTCGCCGCCATGGACGTGCGCGTGGGCCACTCGCCCGCGGGCGCCTGGTTG
GCCGTCACCAGCATCTCCTTCGACATCTCCGTCCTGGAGTTGCTGTGGACGCTCACCCGCGGCTTCAAGGTGGTGGTGCA
AGGGGAGGGGGCTTCGCTCAAGGCGCCCGCTCGCGCCGCGGGGGCCCGGAAGCGCCCCATGGACTTCAGCCTGTTCTACT
TCGCGGATGACGCGGAGGTGTCGCGCGGGGAGAGCAGCTACCGGCTGTTGCTGGAGGGCGCGAAGTTCGCGGACACTCAC
GGCTTCGCGGCGGTGTGGACGCCGGAGCGCCACTTCCACGCCTTCGGCGGCCTGTACCCCAATCCCTCCGTGGTGGGCGC
GGCTGTCGCCACCGTGACGAAGCGCGTGGCCATCCGCGCGGGCAGCGTGGTGCTGCCACTCCACCATCCCGTGCGCGTGG
CGGAGGAGTGGTCCCTGGTGGACAACCTGTCCGGCGGGCGCGTGGGCATCTCCGTCGCTTCCGGCTGGCATGCCAATGAC
TTCGTCTTCGCGCCGGAGAAGTACGAGCAGCGCCGTGAGCTGATGATGGAAGGCATCGACACCGTGCGCCGGCTGTGGCG
TGGGGAGACGGTGCGCTTCCCGGGCGGCGGCGGCGCGCAGGTGGATGTGAAGCTGCGCCCCCGTCCCGTGCAGGCGGAGC
TGCCCGTGTGGCTCACCGCCGCGGGAAACCCGGAGACGTTCATCACCGCGGGCCGGCTGGGGTGCAACATCCTCACGCAC
CTGCTGGGGCAGACGTGGGAGGACCTGGAGAAGAAGCTGTCACTTTACCGTCAGGCCTGGCGCGACGCGGGCCACGCGGG
CGAGGGCCACGTCACCCTCATGCTGCACACCTTCATCGGCGAGGACATGGCGAAGGTGCGCGAGGTGGTGGAGCAGCCCT
TCCGCAACTACCTCAAGAGCTCGGCCGACCTGATGCGCGGCCTGGGGAGCACGCTGGGCATCGACATGGATTCGGCCACG
GAGGCGGACCTGGACCGGCTCGCCGGCCATGCCTTCGACCGCTACTTCGAGACGAGCGGCCTGTTCGGCACGCCGCGTTC
GGTGCGCGAGCGCGTCGGGCAGCTCTACTCTCTGGGCGTGGACGAGGTGGGGTGCCTCATCGACTTCGGTATTCCCGCAG
ACACGGTGCTGGCCAGCCTGCCGCTGCTGGACGAAGTGCGGCAGCGCTGCGTGCGGGACAGCCGCCGCGCGGGCACGGCG
AAGACGATTCCCGAGCAGCTCCGCGAGCACGGCGTGACGCACCTGCAGTGCACGCCGTCCCTGGCGCGCGCGCTGCTGTC
CGAGCCCGAGTCCGTCGAGGCGCTGGGCGGCCTGCAACGGCTGATGGTGGGCGGCGAGGCCCTTCCGGGCGCGTTGGCCG
CGTCCCTGCGCAAGGCGCTGCCGGAGTCCGCCGAGCTGCTCAACATGTACGGCCCCACGGAGACGACCATCTGGTCCTCC
ACGGCGCGCGTGACCCCGGAGGAGACGGCGGCCGTCGTCTCCATTGGCACGCCACTGCTGCGCACGTGCTTGTACGTCCT
CGACGCACGGATGCGGCCGGCGCCGGTGGGCGTGGCGGGTGAGCTGTACATCGGCGGCGCGGGCGTGGTGCGTGGCTATT
TGGGCCGGCCCGAGCTGACGGCGGAGCGCTTCATTCCGGATGCCTGGGCCCGTGAGCCCGGGGCCCGGCTGTATCGCACG
GGGGACCGCGCACGGTGGCGGCCCGACGGCACCATGGAGTTCCTCGGCCGTGTGGACCACCAGCTCAAGGTGCGTGGCTT
CCGCATCGAGGCGGGGGAAATCGAGGCGGCGCTCACCGCCCAGCCCTCGGTGCGCGAGGCGGTGGTGGTGGCGCGCGAGG
ATGTGCCCGGCGACGTGCGGCTCGTGGCCTACGTGGTGCCCGCGCAGGGCGCCACGGTGGAGGCGTCCGCGCTGCGCGAC
GCCCTGGCTCAGCGGTTGCCGGAGCACATGGTTCCGTCGCTCGTCATGGAGCTACCGGCGCTCCCGTTGACGCCCAATGG
CAAGGTGGACCGCAGGGCCCTGCCCACGCCGAACGTGGTGCGCTCCGCGAAAGCGGCCTTCGTGGCGCCGCAGGGGCAAC
TGGAGGAGCAGATTGCCCAGGTGTGGCGCAGCGTCCTCCGTGTGGAGCAGGTGGGCGTGCACGACAACTTCTTCGACCTG
GGCGGCCACTCGCTCCTGATGGTGCAGGTGCACACCCAGCTCAAGTCGGTGCTGGGCCAGGACCTGCCCCTGCTGAAGCT
GCTGGAGCACCCCACCATCAGCACCCTGGCGCGTTTCGCGCGGCAGGGGCCCGCGGCGGCGCAGTCCCAGGTGGAAGCCG
CGCAGGACCGGGCCAAGCGGCAGTTGGAGAGCCTCAAGCGTCAGCGTCAGCGCGCCAGGAAGTAG

Upstream 100 bases:

>100_bases
GGGGGCCTTGGCCGGAAGATGTTTGCCGGGGGGTTCTCCGTGCTCAGCCGGATGTCGTGGCCGCGTGTCAACCCGGGCCG
TGTCCAGCGCAGGAGAAGAC

Downstream 100 bases:

>100_bases
CGGCGCGGGGAGCGCGCGGGCTACGCGCGCGTTTCGTTCAGCGCCTGCCGGATGGCGCGTGCCACCGGCGAGGCGTCGTC
CTCCGGGCCCTGTACCGAGA

Product: non-ribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 2154; Mature: 2153

Protein sequence:

>2154_residues
MTEHIEPRAHRFPTLVDVLCQRAESQGDALLYRFLETGDVDGPVEEWTYRRLDSRARSLGARLRALGAQGERALLLYPPG
LEFVAGFMGCLYGGVIAVPCYPPDPTRLERTLPRLRAIARDCGARYVLTTSTIQEMAEFLTPQAPELGELQWIASDAVPE
AEAADWKRPDLTSESLAFLQYTSGSTGNPKGVKVSHANILHNESLITRDFGLQAERSVGVGWLPMFHDMGLIGKVLQPLY
LGFPCVLMSPIAFLQRPLRWLEAVSHFKGTVSGGPNFAYDLCARKARAEDVARLDLSHWDLAFNGAEPVRRETMERFAET
FAPAGFRREAFYPCYGLAEATLIVSGGVKGTPCVQERYDTGSLELGRAKPASDAAEGPTARTLVSSGQGAPDQRLLIVDP
ETRVPRASNEVGEVWVAGPSVAGGYWDRPEETAHAFGARLANGEGPFLRTGDLAFLSPEGELFITGRLKDLLIVRGRNLY
PQDLEMTAERAHRAVRPGCSAAFSVDVEGEERLVVVSEVDVREGFDGAAVVGALRRALADEHQVHAHTVVLLQARSIPKT
SSGKIQRRACRDGFLAGSLEVVEVSGEEAAPVPEAVPSTPSAPLRERLALASEEARPALLVDFLRVEAARVLRAAPASLA
PETSLASLGLDSLMALELHGRLEEELGVSLPVAFLWQHPTLGTAAAHLVDAWKGSAAPAAPPLKAGSLEGELPLSPGQQR
LWFLDRLVPESALYNVHFQLRLSGALDVPALERALQGLLSRHAVLRAAFPEVEGQPRQLLPPLRPLDVAREDLRALSPAE
RDARLNQLARAQGEAPFNLSEGLLVRAALVALEDQEHVLLMTQHHIVTDGWSIGVLARELAALYRAEVAGAAASLGAPAL
QYVDYARWQRGLGGALDGQRAYWARKLENLPRLELPTDFPRPREPGFRGALHRFALPAELVDSLKAVGRSEGCTFFVTLA
AAWAALLHRYSGQDDFGLGTIFAQRDRAELRDVVGFFASTLVLRADVSGAPRFRELLGRMRHTFHEALAHADLPFEEVVG
ASRAVRGGDNPLFQANLVLESLPPVDMDVPGMQWRPVLPVPDGAVEGTAKFDLQLAVVETPRGLEGALEYRSDLFSAETM
ARLAGHLEALLRGIVAAPDARVEDLPLLDEAERRSLLERWNDFTAPLSQDASHCIHAQFREQAARTPDAVAVVAEDGTLT
YAELARRASALALHLRGLGVGPEVRVGLCAERSVEMVAGMLGILEAGGAYVPLDPDYPRERLTYMLEDSGARVLVTQSHL
AGTLPVAGLHTVLLDTAEPYAAMPASPLALGTTPDNAAYVIYTSGSTGRPKGVVVPHGGVANFFAAMDVRVGHSPAGAWL
AVTSISFDISVLELLWTLTRGFKVVVQGEGASLKAPARAAGARKRPMDFSLFYFADDAEVSRGESSYRLLLEGAKFADTH
GFAAVWTPERHFHAFGGLYPNPSVVGAAVATVTKRVAIRAGSVVLPLHHPVRVAEEWSLVDNLSGGRVGISVASGWHAND
FVFAPEKYEQRRELMMEGIDTVRRLWRGETVRFPGGGGAQVDVKLRPRPVQAELPVWLTAAGNPETFITAGRLGCNILTH
LLGQTWEDLEKKLSLYRQAWRDAGHAGEGHVTLMLHTFIGEDMAKVREVVEQPFRNYLKSSADLMRGLGSTLGIDMDSAT
EADLDRLAGHAFDRYFETSGLFGTPRSVRERVGQLYSLGVDEVGCLIDFGIPADTVLASLPLLDEVRQRCVRDSRRAGTA
KTIPEQLREHGVTHLQCTPSLARALLSEPESVEALGGLQRLMVGGEALPGALAASLRKALPESAELLNMYGPTETTIWSS
TARVTPEETAAVVSIGTPLLRTCLYVLDARMRPAPVGVAGELYIGGAGVVRGYLGRPELTAERFIPDAWAREPGARLYRT
GDRARWRPDGTMEFLGRVDHQLKVRGFRIEAGEIEAALTAQPSVREAVVVAREDVPGDVRLVAYVVPAQGATVEASALRD
ALAQRLPEHMVPSLVMELPALPLTPNGKVDRRALPTPNVVRSAKAAFVAPQGQLEEQIAQVWRSVLRVEQVGVHDNFFDL
GGHSLLMVQVHTQLKSVLGQDLPLLKLLEHPTISTLARFARQGPAAAQSQVEAAQDRAKRQLESLKRQRQRARK

Sequences:

>Translated_2154_residues
MTEHIEPRAHRFPTLVDVLCQRAESQGDALLYRFLETGDVDGPVEEWTYRRLDSRARSLGARLRALGAQGERALLLYPPG
LEFVAGFMGCLYGGVIAVPCYPPDPTRLERTLPRLRAIARDCGARYVLTTSTIQEMAEFLTPQAPELGELQWIASDAVPE
AEAADWKRPDLTSESLAFLQYTSGSTGNPKGVKVSHANILHNESLITRDFGLQAERSVGVGWLPMFHDMGLIGKVLQPLY
LGFPCVLMSPIAFLQRPLRWLEAVSHFKGTVSGGPNFAYDLCARKARAEDVARLDLSHWDLAFNGAEPVRRETMERFAET
FAPAGFRREAFYPCYGLAEATLIVSGGVKGTPCVQERYDTGSLELGRAKPASDAAEGPTARTLVSSGQGAPDQRLLIVDP
ETRVPRASNEVGEVWVAGPSVAGGYWDRPEETAHAFGARLANGEGPFLRTGDLAFLSPEGELFITGRLKDLLIVRGRNLY
PQDLEMTAERAHRAVRPGCSAAFSVDVEGEERLVVVSEVDVREGFDGAAVVGALRRALADEHQVHAHTVVLLQARSIPKT
SSGKIQRRACRDGFLAGSLEVVEVSGEEAAPVPEAVPSTPSAPLRERLALASEEARPALLVDFLRVEAARVLRAAPASLA
PETSLASLGLDSLMALELHGRLEEELGVSLPVAFLWQHPTLGTAAAHLVDAWKGSAAPAAPPLKAGSLEGELPLSPGQQR
LWFLDRLVPESALYNVHFQLRLSGALDVPALERALQGLLSRHAVLRAAFPEVEGQPRQLLPPLRPLDVAREDLRALSPAE
RDARLNQLARAQGEAPFNLSEGLLVRAALVALEDQEHVLLMTQHHIVTDGWSIGVLARELAALYRAEVAGAAASLGAPAL
QYVDYARWQRGLGGALDGQRAYWARKLENLPRLELPTDFPRPREPGFRGALHRFALPAELVDSLKAVGRSEGCTFFVTLA
AAWAALLHRYSGQDDFGLGTIFAQRDRAELRDVVGFFASTLVLRADVSGAPRFRELLGRMRHTFHEALAHADLPFEEVVG
ASRAVRGGDNPLFQANLVLESLPPVDMDVPGMQWRPVLPVPDGAVEGTAKFDLQLAVVETPRGLEGALEYRSDLFSAETM
ARLAGHLEALLRGIVAAPDARVEDLPLLDEAERRSLLERWNDFTAPLSQDASHCIHAQFREQAARTPDAVAVVAEDGTLT
YAELARRASALALHLRGLGVGPEVRVGLCAERSVEMVAGMLGILEAGGAYVPLDPDYPRERLTYMLEDSGARVLVTQSHL
AGTLPVAGLHTVLLDTAEPYAAMPASPLALGTTPDNAAYVIYTSGSTGRPKGVVVPHGGVANFFAAMDVRVGHSPAGAWL
AVTSISFDISVLELLWTLTRGFKVVVQGEGASLKAPARAAGARKRPMDFSLFYFADDAEVSRGESSYRLLLEGAKFADTH
GFAAVWTPERHFHAFGGLYPNPSVVGAAVATVTKRVAIRAGSVVLPLHHPVRVAEEWSLVDNLSGGRVGISVASGWHAND
FVFAPEKYEQRRELMMEGIDTVRRLWRGETVRFPGGGGAQVDVKLRPRPVQAELPVWLTAAGNPETFITAGRLGCNILTH
LLGQTWEDLEKKLSLYRQAWRDAGHAGEGHVTLMLHTFIGEDMAKVREVVEQPFRNYLKSSADLMRGLGSTLGIDMDSAT
EADLDRLAGHAFDRYFETSGLFGTPRSVRERVGQLYSLGVDEVGCLIDFGIPADTVLASLPLLDEVRQRCVRDSRRAGTA
KTIPEQLREHGVTHLQCTPSLARALLSEPESVEALGGLQRLMVGGEALPGALAASLRKALPESAELLNMYGPTETTIWSS
TARVTPEETAAVVSIGTPLLRTCLYVLDARMRPAPVGVAGELYIGGAGVVRGYLGRPELTAERFIPDAWAREPGARLYRT
GDRARWRPDGTMEFLGRVDHQLKVRGFRIEAGEIEAALTAQPSVREAVVVAREDVPGDVRLVAYVVPAQGATVEASALRD
ALAQRLPEHMVPSLVMELPALPLTPNGKVDRRALPTPNVVRSAKAAFVAPQGQLEEQIAQVWRSVLRVEQVGVHDNFFDL
GGHSLLMVQVHTQLKSVLGQDLPLLKLLEHPTISTLARFARQGPAAAQSQVEAAQDRAKRQLESLKRQRQRARK
>Mature_2153_residues
TEHIEPRAHRFPTLVDVLCQRAESQGDALLYRFLETGDVDGPVEEWTYRRLDSRARSLGARLRALGAQGERALLLYPPGL
EFVAGFMGCLYGGVIAVPCYPPDPTRLERTLPRLRAIARDCGARYVLTTSTIQEMAEFLTPQAPELGELQWIASDAVPEA
EAADWKRPDLTSESLAFLQYTSGSTGNPKGVKVSHANILHNESLITRDFGLQAERSVGVGWLPMFHDMGLIGKVLQPLYL
GFPCVLMSPIAFLQRPLRWLEAVSHFKGTVSGGPNFAYDLCARKARAEDVARLDLSHWDLAFNGAEPVRRETMERFAETF
APAGFRREAFYPCYGLAEATLIVSGGVKGTPCVQERYDTGSLELGRAKPASDAAEGPTARTLVSSGQGAPDQRLLIVDPE
TRVPRASNEVGEVWVAGPSVAGGYWDRPEETAHAFGARLANGEGPFLRTGDLAFLSPEGELFITGRLKDLLIVRGRNLYP
QDLEMTAERAHRAVRPGCSAAFSVDVEGEERLVVVSEVDVREGFDGAAVVGALRRALADEHQVHAHTVVLLQARSIPKTS
SGKIQRRACRDGFLAGSLEVVEVSGEEAAPVPEAVPSTPSAPLRERLALASEEARPALLVDFLRVEAARVLRAAPASLAP
ETSLASLGLDSLMALELHGRLEEELGVSLPVAFLWQHPTLGTAAAHLVDAWKGSAAPAAPPLKAGSLEGELPLSPGQQRL
WFLDRLVPESALYNVHFQLRLSGALDVPALERALQGLLSRHAVLRAAFPEVEGQPRQLLPPLRPLDVAREDLRALSPAER
DARLNQLARAQGEAPFNLSEGLLVRAALVALEDQEHVLLMTQHHIVTDGWSIGVLARELAALYRAEVAGAAASLGAPALQ
YVDYARWQRGLGGALDGQRAYWARKLENLPRLELPTDFPRPREPGFRGALHRFALPAELVDSLKAVGRSEGCTFFVTLAA
AWAALLHRYSGQDDFGLGTIFAQRDRAELRDVVGFFASTLVLRADVSGAPRFRELLGRMRHTFHEALAHADLPFEEVVGA
SRAVRGGDNPLFQANLVLESLPPVDMDVPGMQWRPVLPVPDGAVEGTAKFDLQLAVVETPRGLEGALEYRSDLFSAETMA
RLAGHLEALLRGIVAAPDARVEDLPLLDEAERRSLLERWNDFTAPLSQDASHCIHAQFREQAARTPDAVAVVAEDGTLTY
AELARRASALALHLRGLGVGPEVRVGLCAERSVEMVAGMLGILEAGGAYVPLDPDYPRERLTYMLEDSGARVLVTQSHLA
GTLPVAGLHTVLLDTAEPYAAMPASPLALGTTPDNAAYVIYTSGSTGRPKGVVVPHGGVANFFAAMDVRVGHSPAGAWLA
VTSISFDISVLELLWTLTRGFKVVVQGEGASLKAPARAAGARKRPMDFSLFYFADDAEVSRGESSYRLLLEGAKFADTHG
FAAVWTPERHFHAFGGLYPNPSVVGAAVATVTKRVAIRAGSVVLPLHHPVRVAEEWSLVDNLSGGRVGISVASGWHANDF
VFAPEKYEQRRELMMEGIDTVRRLWRGETVRFPGGGGAQVDVKLRPRPVQAELPVWLTAAGNPETFITAGRLGCNILTHL
LGQTWEDLEKKLSLYRQAWRDAGHAGEGHVTLMLHTFIGEDMAKVREVVEQPFRNYLKSSADLMRGLGSTLGIDMDSATE
ADLDRLAGHAFDRYFETSGLFGTPRSVRERVGQLYSLGVDEVGCLIDFGIPADTVLASLPLLDEVRQRCVRDSRRAGTAK
TIPEQLREHGVTHLQCTPSLARALLSEPESVEALGGLQRLMVGGEALPGALAASLRKALPESAELLNMYGPTETTIWSST
ARVTPEETAAVVSIGTPLLRTCLYVLDARMRPAPVGVAGELYIGGAGVVRGYLGRPELTAERFIPDAWAREPGARLYRTG
DRARWRPDGTMEFLGRVDHQLKVRGFRIEAGEIEAALTAQPSVREAVVVAREDVPGDVRLVAYVVPAQGATVEASALRDA
LAQRLPEHMVPSLVMELPALPLTPNGKVDRRALPTPNVVRSAKAAFVAPQGQLEEQIAQVWRSVLRVEQVGVHDNFFDLG
GHSLLMVQVHTQLKSVLGQDLPLLKLLEHPTISTLARFARQGPAAAQSQVEAAQDRAKRQLESLKRQRQRARK

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI225735629, Length=609, Percent_Identity=29.3924466338259, Blast_Score=181, Evalue=6e-45,
Organism=Homo sapiens, GI45827692, Length=609, Percent_Identity=29.3924466338259, Blast_Score=181, Evalue=7e-45,
Organism=Homo sapiens, GI44888818, Length=613, Percent_Identity=27.8955954323002, Blast_Score=180, Evalue=2e-44,
Organism=Homo sapiens, GI55749758, Length=610, Percent_Identity=28.0327868852459, Blast_Score=169, Evalue=4e-41,
Organism=Homo sapiens, GI225735625, Length=613, Percent_Identity=26.4274061990212, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI45827694, Length=545, Percent_Identity=26.4220183486239, Blast_Score=105, Evalue=6e-22,
Organism=Homo sapiens, GI45580730, Length=412, Percent_Identity=24.7572815533981, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI225735627, Length=513, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=4e-19,
Organism=Homo sapiens, GI45827696, Length=513, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=5e-19,
Organism=Homo sapiens, GI45827698, Length=483, Percent_Identity=25.6728778467909, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI38505220, Length=291, Percent_Identity=28.5223367697594, Blast_Score=79, Evalue=6e-14,
Organism=Homo sapiens, GI157311624, Length=297, Percent_Identity=26.2626262626263, Blast_Score=74, Evalue=2e-12,
Organism=Homo sapiens, GI157311622, Length=297, Percent_Identity=26.2626262626263, Blast_Score=74, Evalue=2e-12,
Organism=Homo sapiens, GI187761345, Length=259, Percent_Identity=28.1853281853282, Blast_Score=73, Evalue=3e-12,
Organism=Homo sapiens, GI187761343, Length=259, Percent_Identity=28.1853281853282, Blast_Score=73, Evalue=3e-12,
Organism=Homo sapiens, GI58082049, Length=297, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=5e-11,
Organism=Escherichia coli, GI1786801, Length=362, Percent_Identity=41.4364640883978, Blast_Score=212, Evalue=2e-55,
Organism=Escherichia coli, GI1788107, Length=608, Percent_Identity=26.1513157894737, Blast_Score=131, Evalue=6e-31,
Organism=Escherichia coli, GI145693145, Length=559, Percent_Identity=23.7924865831843, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1786810, Length=251, Percent_Identity=29.8804780876494, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI221142682, Length=282, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193202679, Length=598, Percent_Identity=26.2541806020067, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17556356, Length=359, Percent_Identity=26.7409470752089, Blast_Score=130, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=330, Percent_Identity=24.8484848484848, Blast_Score=100, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559526, Length=559, Percent_Identity=24.5080500894454, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531443, Length=412, Percent_Identity=24.5145631067961, Blast_Score=91, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560308, Length=275, Percent_Identity=25.0909090909091, Blast_Score=69, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=458, Percent_Identity=28.82096069869, Blast_Score=177, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319699, Length=271, Percent_Identity=25.0922509225092, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648676, Length=360, Percent_Identity=30.5555555555556, Blast_Score=120, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24654656, Length=469, Percent_Identity=25.1599147121535, Blast_Score=119, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18859661, Length=558, Percent_Identity=24.1935483870968, Blast_Score=108, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24581924, Length=606, Percent_Identity=25.4125412541254, Blast_Score=103, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667955, Length=137, Percent_Identity=34.3065693430657, Blast_Score=73, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62472339, Length=137, Percent_Identity=34.3065693430657, Blast_Score=73, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24667959, Length=137, Percent_Identity=34.3065693430657, Blast_Score=72, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356947, Length=274, Percent_Identity=25.9124087591241, Blast_Score=69, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 233802; Mature: 233671

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHIEPRAHRFPTLVDVLCQRAESQGDALLYRFLETGDVDGPVEEWTYRRLDSRARSLG
CCCCCCCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ARLRALGAQGERALLLYPPGLEFVAGFMGCLYGGVIAVPCYPPDPTRLERTLPRLRAIAR
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHH
DCGARYVLTTSTIQEMAEFLTPQAPELGELQWIASDAVPEAEAADWKRPDLTSESLAFLQ
HCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEE
YTSGSTGNPKGVKVSHANILHNESLITRDFGLQAERSVGVGWLPMFHDMGLIGKVLQPLY
ECCCCCCCCCCEEEEHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGFPCVLMSPIAFLQRPLRWLEAVSHFKGTVSGGPNFAYDLCARKARAEDVARLDLSHWD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LAFNGAEPVRRETMERFAETFAPAGFRREAFYPCYGLAEATLIVSGGVKGTPCVQERYDT
EEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCC
GSLELGRAKPASDAAEGPTARTLVSSGQGAPDQRLLIVDPETRVPRASNEVGEVWVAGPS
CCEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCC
VAGGYWDRPEETAHAFGARLANGEGPFLRTGDLAFLSPEGELFITGRLKDLLIVRGRNLY
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCEEEEECCCEEEEECCCCCC
PQDLEMTAERAHRAVRPGCSAAFSVDVEGEERLVVVSEVDVREGFDGAAVVGALRRALAD
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHC
EHQVHAHTVVLLQARSIPKTSSGKIQRRACRDGFLAGSLEVVEVSGEEAAPVPEAVPSTP
CHHHHHEEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC
SAPLRERLALASEEARPALLVDFLRVEAARVLRAAPASLAPETSLASLGLDSLMALELHG
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHH
RLEEELGVSLPVAFLWQHPTLGTAAAHLVDAWKGSAAPAAPPLKAGSLEGELPLSPGQQR
HHHHHCCCCCCHHHEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LWFLDRLVPESALYNVHFQLRLSGALDVPALERALQGLLSRHAVLRAAFPEVEGQPRQLL
HHHHHHHCCCHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
PPLRPLDVAREDLRALSPAERDARLNQLARAQGEAPFNLSEGLLVRAALVALEDQEHVLL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEE
MTQHHIVTDGWSIGVLARELAALYRAEVAGAAASLGAPALQYVDYARWQRGLGGALDGQR
EEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHH
AYWARKLENLPRLELPTDFPRPREPGFRGALHRFALPAELVDSLKAVGRSEGCTFFVTLA
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEHHHHH
AAWAALLHRYSGQDDFGLGTIFAQRDRAELRDVVGFFASTLVLRADVSGAPRFRELLGRM
HHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
RHTFHEALAHADLPFEEVVGASRAVRGGDNPLFQANLVLESLPPVDMDVPGMQWRPVLPV
HHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCEECCCC
PDGAVEGTAKFDLQLAVVETPRGLEGALEYRSDLFSAETMARLAGHLEALLRGIVAAPDA
CCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RVEDLPLLDEAERRSLLERWNDFTAPLSQDASHCIHAQFREQAARTPDAVAVVAEDGTLT
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
YAELARRASALALHLRGLGVGPEVRVGLCAERSVEMVAGMLGILEAGGAYVPLDPDYPRE
HHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHH
RLTYMLEDSGARVLVTQSHLAGTLPVAGLHTVLLDTAEPYAAMPASPLALGTTPDNAAYV
HHHEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEE
IYTSGSTGRPKGVVVPHGGVANFFAAMDVRVGHSPAGAWLAVTSISFDISVLELLWTLTR
EEECCCCCCCCEEEECCCCHHHHHHHHHEEECCCCCCCEEEEEEECCHHHHHHHHHHHHC
GFKVVVQGEGASLKAPARAAGARKRPMDFSLFYFADDAEVSRGESSYRLLLEGAKFADTH
CCEEEEECCCCCCCCCHHHCCCCCCCCCEEEEEEECCCHHCCCCCCEEEEEECCCCCCCC
GFAAVWTPERHFHAFGGLYPNPSVVGAAVATVTKRVAIRAGSVVLPLHHPVRVAEEWSLV
CEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
DNLSGGRVGISVASGWHANDFVFAPEKYEQRRELMMEGIDTVRRLWRGETVRFPGGGGAQ
HCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCE
VDVKLRPRPVQAELPVWLTAAGNPETFITAGRLGCNILTHLLGQTWEDLEKKLSLYRQAW
EEEEECCCCCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RDAGHAGEGHVTLMLHTFIGEDMAKVREVVEQPFRNYLKSSADLMRGLGSTLGIDMDSAT
HCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
EADLDRLAGHAFDRYFETSGLFGTPRSVRERVGQLYSLGVDEVGCLIDFGIPADTVLASL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCEEEECCCCHHHHHHHC
PLLDEVRQRCVRDSRRAGTAKTIPEQLREHGVTHLQCTPSLARALLSEPESVEALGGLQR
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHHHH
LMVGGEALPGALAASLRKALPESAELLNMYGPTETTIWSSTARVTPEETAAVVSIGTPLL
HHHCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCCCCCHHHHEEEEECCHHHH
RTCLYVLDARMRPAPVGVAGELYIGGAGVVRGYLGRPELTAERFIPDAWAREPGARLYRT
HHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCHHHCCCCHHCCCCCCHHEEC
GDRARWRPDGTMEFLGRVDHQLKVRGFRIEAGEIEAALTAQPSVREAVVVAREDVPGDVR
CCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCEEEECCCCHHHEEEEEECCCCCCEE
LVAYVVPAQGATVEASALRDALAQRLPEHMVPSLVMELPALPLTPNGKVDRRALPTPNVV
EEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
RSAKAAFVAPQGQLEEQIAQVWRSVLRVEQVGVHDNFFDLGGHSLLMVQVHTQLKSVLGQ
HHCHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHCC
DLPLLKLLEHPTISTLARFARQGPAAAQSQVEAAQDRAKRQLESLKRQRQRARK
CCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEHIEPRAHRFPTLVDVLCQRAESQGDALLYRFLETGDVDGPVEEWTYRRLDSRARSLG
CCCCCCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ARLRALGAQGERALLLYPPGLEFVAGFMGCLYGGVIAVPCYPPDPTRLERTLPRLRAIAR
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHH
DCGARYVLTTSTIQEMAEFLTPQAPELGELQWIASDAVPEAEAADWKRPDLTSESLAFLQ
HCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEE
YTSGSTGNPKGVKVSHANILHNESLITRDFGLQAERSVGVGWLPMFHDMGLIGKVLQPLY
ECCCCCCCCCCEEEEHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGFPCVLMSPIAFLQRPLRWLEAVSHFKGTVSGGPNFAYDLCARKARAEDVARLDLSHWD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LAFNGAEPVRRETMERFAETFAPAGFRREAFYPCYGLAEATLIVSGGVKGTPCVQERYDT
EEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCC
GSLELGRAKPASDAAEGPTARTLVSSGQGAPDQRLLIVDPETRVPRASNEVGEVWVAGPS
CCEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCC
VAGGYWDRPEETAHAFGARLANGEGPFLRTGDLAFLSPEGELFITGRLKDLLIVRGRNLY
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCEEEEECCCEEEEECCCCCC
PQDLEMTAERAHRAVRPGCSAAFSVDVEGEERLVVVSEVDVREGFDGAAVVGALRRALAD
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHC
EHQVHAHTVVLLQARSIPKTSSGKIQRRACRDGFLAGSLEVVEVSGEEAAPVPEAVPSTP
CHHHHHEEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC
SAPLRERLALASEEARPALLVDFLRVEAARVLRAAPASLAPETSLASLGLDSLMALELHG
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHH
RLEEELGVSLPVAFLWQHPTLGTAAAHLVDAWKGSAAPAAPPLKAGSLEGELPLSPGQQR
HHHHHCCCCCCHHHEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LWFLDRLVPESALYNVHFQLRLSGALDVPALERALQGLLSRHAVLRAAFPEVEGQPRQLL
HHHHHHHCCCHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
PPLRPLDVAREDLRALSPAERDARLNQLARAQGEAPFNLSEGLLVRAALVALEDQEHVLL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEE
MTQHHIVTDGWSIGVLARELAALYRAEVAGAAASLGAPALQYVDYARWQRGLGGALDGQR
EEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHH
AYWARKLENLPRLELPTDFPRPREPGFRGALHRFALPAELVDSLKAVGRSEGCTFFVTLA
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEHHHHH
AAWAALLHRYSGQDDFGLGTIFAQRDRAELRDVVGFFASTLVLRADVSGAPRFRELLGRM
HHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
RHTFHEALAHADLPFEEVVGASRAVRGGDNPLFQANLVLESLPPVDMDVPGMQWRPVLPV
HHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCEECCCC
PDGAVEGTAKFDLQLAVVETPRGLEGALEYRSDLFSAETMARLAGHLEALLRGIVAAPDA
CCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RVEDLPLLDEAERRSLLERWNDFTAPLSQDASHCIHAQFREQAARTPDAVAVVAEDGTLT
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
YAELARRASALALHLRGLGVGPEVRVGLCAERSVEMVAGMLGILEAGGAYVPLDPDYPRE
HHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHH
RLTYMLEDSGARVLVTQSHLAGTLPVAGLHTVLLDTAEPYAAMPASPLALGTTPDNAAYV
HHHEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEE
IYTSGSTGRPKGVVVPHGGVANFFAAMDVRVGHSPAGAWLAVTSISFDISVLELLWTLTR
EEECCCCCCCCEEEECCCCHHHHHHHHHEEECCCCCCCEEEEEEECCHHHHHHHHHHHHC
GFKVVVQGEGASLKAPARAAGARKRPMDFSLFYFADDAEVSRGESSYRLLLEGAKFADTH
CCEEEEECCCCCCCCCHHHCCCCCCCCCEEEEEEECCCHHCCCCCCEEEEEECCCCCCCC
GFAAVWTPERHFHAFGGLYPNPSVVGAAVATVTKRVAIRAGSVVLPLHHPVRVAEEWSLV
CEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
DNLSGGRVGISVASGWHANDFVFAPEKYEQRRELMMEGIDTVRRLWRGETVRFPGGGGAQ
HCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCE
VDVKLRPRPVQAELPVWLTAAGNPETFITAGRLGCNILTHLLGQTWEDLEKKLSLYRQAW
EEEEECCCCCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RDAGHAGEGHVTLMLHTFIGEDMAKVREVVEQPFRNYLKSSADLMRGLGSTLGIDMDSAT
HCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
EADLDRLAGHAFDRYFETSGLFGTPRSVRERVGQLYSLGVDEVGCLIDFGIPADTVLASL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCEEEECCCCHHHHHHHC
PLLDEVRQRCVRDSRRAGTAKTIPEQLREHGVTHLQCTPSLARALLSEPESVEALGGLQR
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHHHH
LMVGGEALPGALAASLRKALPESAELLNMYGPTETTIWSSTARVTPEETAAVVSIGTPLL
HHHCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCCCCCHHHHEEEEECCHHHH
RTCLYVLDARMRPAPVGVAGELYIGGAGVVRGYLGRPELTAERFIPDAWAREPGARLYRT
HHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCHHHCCCCHHCCCCCCHHEEC
GDRARWRPDGTMEFLGRVDHQLKVRGFRIEAGEIEAALTAQPSVREAVVVAREDVPGDVR
CCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCEEEECCCCHHHEEEEEECCCCCCEE
LVAYVVPAQGATVEASALRDALAQRLPEHMVPSLVMELPALPLTPNGKVDRRALPTPNVV
EEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
RSAKAAFVAPQGQLEEQIAQVWRSVLRVEQVGVHDNFFDLGGHSLLMVQVHTQLKSVLGQ
HHCHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHCC
DLPLLKLLEHPTISTLARFARQGPAAAQSQVEAAQDRAKRQLESLKRQRQRARK
CCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA