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The map label for this gene is ilvE [H]

Identifier: 108760638

GI number: 108760638

Start: 3500690

End: 3501637

Strand: Reverse

Name: ilvE [H]

Synonym: MXAN_2987

Alternate gene names: 108760638

Gene position: 3501637-3500690 (Counterclockwise)

Preceding gene: 108759327

Following gene: 108763215

Centisome position: 38.31

GC content: 65.72

Gene sequence:

>948_bases
ATGAGCTCGACCTCGAGTAGTGGAGTGCGCGCCGAGCAAATCTGGCTCGACGGCCGACTGATGAAATGGGACGAGGGCCA
CGTGCATCTGATGACGCACGCGCTTCACTACGGCCTGGGTGTCTTCGAGGGCATCCGCGCATACAAAACGCATGACGGAC
GGCTGGCCGTCTTCCGGCTGCGTGAGCACGTCCGCCGGCTGCTCGACTCGGCCCACATCATCATGCTGAAGATTCCGTAC
ACCGAGGACGAGCTCTTCGACGCGTGCGTGAATCTGCTCCGCGCGCAGAAGGACCTGTTCGCCAACGGCGCGTACCTGCG
GCCGGTGGCCTTCATGGGCGACGGCGCCATGGGCCTGGGCGCGGTGAACCCCACCCGCACGGCCGTGACGGCCTGGGACT
GGGGCGCGTACCTGGGCGACAAGGGCATCAAGGAAGGTATCCGCGCCAAGGTCAGCTCGTACACGCGCATGCACGTCAAC
GTGAACATGGTGCGCGGGAAGATTACCGGCCAGTACGTCAACTCCATCCTCGCCAAGCGCGAGGCGGTGCTGGCGGGCTA
CGACGAGGCCATCCTCCTGGACATCAGCGGCTTCGTGGCCGAGGCCTCCGGCGAGAACATCTTCCAGGTGAACAAGAAGG
GCATCATCAAGACGCCCCCGCTGTCCGGCCCCATCCTGGACGGCATCACCCGCGACACGGTGCTGCACATCCTGCGCGAC
AGCGGCCGCACGGTGGAGGAGGTCACCTTCACCCGCGACGCGCTCTACATCACCAACGAGATCTTCCTCTGCGGCACGGC
GGCGGAGATCACCCCCGTGCGCGAGGTGGACAACCGCCAGGTGGCTGACGGCAAGCCCGGCCCCATCACCCGGTACGTGC
AGGACATGTACTTCCGCATCGTGCGCGGCCAGGAGCCGCGCTACGCGGATTGGCTCACGTACATCTGA

Upstream 100 bases:

>100_bases
GTGACTGTTTCGGGACGAGAAACACGCTTTGACCTCATAGGTTTCACTGGCTAGAAGGCCCTGGCTGTCCCCCCTCAACA
TCCAGGCGAAGGAACATCGA

Downstream 100 bases:

>100_bases
GCCACCCCGCTTCGCCCCCCTCTTCGGCATGGGAGGGGGGCGGGCAGCCAGGGAAGAGGCCACGTCCCGCGCCCGACCGC
CCATCGAATGGGCTAGAACG

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSSTSSSGVRAEQIWLDGRLMKWDEGHVHLMTHALHYGLGVFEGIRAYKTHDGRLAVFRLREHVRRLLDSAHIIMLKIPY
TEDELFDACVNLLRAQKDLFANGAYLRPVAFMGDGAMGLGAVNPTRTAVTAWDWGAYLGDKGIKEGIRAKVSSYTRMHVN
VNMVRGKITGQYVNSILAKREAVLAGYDEAILLDISGFVAEASGENIFQVNKKGIIKTPPLSGPILDGITRDTVLHILRD
SGRTVEEVTFTRDALYITNEIFLCGTAAEITPVREVDNRQVADGKPGPITRYVQDMYFRIVRGQEPRYADWLTYI

Sequences:

>Translated_315_residues
MSSTSSSGVRAEQIWLDGRLMKWDEGHVHLMTHALHYGLGVFEGIRAYKTHDGRLAVFRLREHVRRLLDSAHIIMLKIPY
TEDELFDACVNLLRAQKDLFANGAYLRPVAFMGDGAMGLGAVNPTRTAVTAWDWGAYLGDKGIKEGIRAKVSSYTRMHVN
VNMVRGKITGQYVNSILAKREAVLAGYDEAILLDISGFVAEASGENIFQVNKKGIIKTPPLSGPILDGITRDTVLHILRD
SGRTVEEVTFTRDALYITNEIFLCGTAAEITPVREVDNRQVADGKPGPITRYVQDMYFRIVRGQEPRYADWLTYI
>Mature_314_residues
SSTSSSGVRAEQIWLDGRLMKWDEGHVHLMTHALHYGLGVFEGIRAYKTHDGRLAVFRLREHVRRLLDSAHIIMLKIPYT
EDELFDACVNLLRAQKDLFANGAYLRPVAFMGDGAMGLGAVNPTRTAVTAWDWGAYLGDKGIKEGIRAKVSSYTRMHVNV
NMVRGKITGQYVNSILAKREAVLAGYDEAILLDISGFVAEASGENIFQVNKKGIIKTPPLSGPILDGITRDTVLHILRDS
GRTVEEVTFTRDALYITNEIFLCGTAAEITPVREVDNRQVADGKPGPITRYVQDMYFRIVRGQEPRYADWLTYI

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=306, Percent_Identity=26.1437908496732, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI258614015, Length=280, Percent_Identity=26.0714285714286, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI48994963, Length=311, Percent_Identity=42.1221864951768, Blast_Score=262, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17565728, Length=291, Percent_Identity=25.7731958762887, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568601, Length=297, Percent_Identity=25.9259259259259, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322608, Length=288, Percent_Identity=28.125, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322002, Length=263, Percent_Identity=27.7566539923954, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 35218; Mature: 35087

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTSSSGVRAEQIWLDGRLMKWDEGHVHLMTHALHYGLGVFEGIRAYKTHDGRLAVFRL
CCCCCCCCCEEEEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHH
REHVRRLLDSAHIIMLKIPYTEDELFDACVNLLRAQKDLFANGAYLRPVAFMGDGAMGLG
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCCCCCC
AVNPTRTAVTAWDWGAYLGDKGIKEGIRAKVSSYTRMHVNVNMVRGKITGQYVNSILAKR
CCCCCCEEEEEECCHHHHCCHHHHHHHHHHHCCEEEEEEEEEEEEEEECHHHHHHHHHHH
EAVLAGYDEAILLDISGFVAEASGENIFQVNKKGIIKTPPLSGPILDGITRDTVLHILRD
HHHHCCCCCEEEEEECCCEEECCCCCEEEECCCCCEECCCCCCCHHCCCHHHHHHHHHHC
SGRTVEEVTFTRDALYITNEIFLCGTAAEITPVREVDNRQVADGKPGPITRYVQDMYFRI
CCCEEHHEEEECCEEEEECEEEEEECCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VRGQEPRYADWLTYI
HCCCCCCHHHHHHCC
>Mature Secondary Structure 
SSTSSSGVRAEQIWLDGRLMKWDEGHVHLMTHALHYGLGVFEGIRAYKTHDGRLAVFRL
CCCCCCCCEEEEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHH
REHVRRLLDSAHIIMLKIPYTEDELFDACVNLLRAQKDLFANGAYLRPVAFMGDGAMGLG
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCCCCCC
AVNPTRTAVTAWDWGAYLGDKGIKEGIRAKVSSYTRMHVNVNMVRGKITGQYVNSILAKR
CCCCCCEEEEEECCHHHHCCHHHHHHHHHHHCCEEEEEEEEEEEEEEECHHHHHHHHHHH
EAVLAGYDEAILLDISGFVAEASGENIFQVNKKGIIKTPPLSGPILDGITRDTVLHILRD
HHHHCCCCCEEEEEECCCEEECCCCCEEEECCCCCEECCCCCCCHHCCCHHHHHHHHHHC
SGRTVEEVTFTRDALYITNEIFLCGTAAEITPVREVDNRQVADGKPGPITRYVQDMYFRI
CCCEEHHEEEECCEEEEECEEEEEECCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VRGQEPRYADWLTYI
HCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]