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The map label for this gene is soxA [H]

Identifier: 108760497

GI number: 108760497

Start: 4825432

End: 4826832

Strand: Direct

Name: soxA [H]

Synonym: MXAN_3962

Alternate gene names: 108760497

Gene position: 4825432-4826832 (Clockwise)

Preceding gene: 108761382

Following gene: 108762486

Centisome position: 52.8

GC content: 73.23

Gene sequence:

>1401_bases
ATGCCGTCAGAGGCTTTGACCGCCCGGTCCGCGTGGGCCATTTTGGCACACCCTATGCGACGCCTTCCCGACGTACCGCC
GCGCGGCCGGGCCATCACCGTGGACCTCGAGGGCGAGAGCCTCCCCGCCATCGAAGGTGAGCCGGTGGCGTGCTCGCTGA
TTGCCGCGGGTGAGCCCATGCTCGCCCGCTCCATCAAGTACCACCGGCCGCGAGGCCCCTACTGCTTCGCCGGGGCCTGC
TCGCATTGCCTGATGCGGGTGGACGGCGTGCCCAATGTCTACGCGTGCCGCACGCCCGCGCGGGACGGCATGAAGCTGGA
GCGGCAGAACGCCTATCCCTCCGCGAAGGTGGACATCTTCGAGAGCATCGACTGGTTCTTCCCCAAGGGCATGGACCACC
ACGAGATGTTCGCCGGCGTCCCGGTGGCTGAGCAGGTGATGGCCAAGGTGGCGCGGCAGCTCGCGGGGCTGGGCCTGCTG
CCCAAGACGCCCGCACCCGCGACGGCGCCCGCGCGCACGGTGCGCACCCGCGTGGCCGTGGTGGGCGGCGGCGCGGCAGG
ACTGGCGGCGGCGCGCGTGTTGACCGAGCGGGACGTGGGCTTCCTCCTCATCGAGCGGGACGACGCGCTCGGCGGCCGGC
TCGCGAACGGCGCGCCGGAAGCCGGCGGCCCCAGCCTGGACGACATCCACCGCATCTCCCCCAGCAGCGTGCTCACGCGG
GCCACCGCGCTGGGCCTGTATGACGACGAGGCGGGGCGCTTCCTCGCGGTGGGCACCTGGGAGGCGGACGCGCCACGTCT
GGTGAAGGTGTACTCGGAGCGCTTCCTGCTCACGCCCGGCGGCCATCCGCCCACGCTCCCCTTCGAGAACAATGACTTGC
CCGGCGTCTACGCGGGACGCGCGGCCAGCCTGCTGCTGCGCCGCTACGACGTGGCGCCGGAGACAGCGGCGCTGGTGGGC
TGGGGCGCGGAGTTGCACGCGCTGGCGAACCTGCTCCAGGAGCGCGGCACGAAGGTGGTGGCGGTGGTGGACCTGCGGGA
CACGCCGCCGGCGGGCACCCATGCCACGGCGGTGCGAGGCAGCGAGCCCAAGGCCCATGGCCTGCGCGGCGTGAGCGCCT
TCAGCTACACGCGCGAGGGCGGCGGACGCGAAAAGGTGTCGTGTGACGCGGTGCTGGTGTCCGTCCCCGTCAGCCCCAGC
TTCGAGCTGGCGCGGCAGGGCGGCGCGAAGGTGCCGTTCGACGAGAAGCGCGGGCTCTTCGTGGTGGAGACGGACGCGGA
CGGGCGCACCCAGGCGCCGGACGTGTACGCCGCGGGTGACGTCACGGGCGGAGGCACCGCGAAGGACGCGGCGGCGGCCG
GACGGCGCGCGGCCCAGGCGCTGGTGGGAGGGCTGTCATGA

Upstream 100 bases:

>100_bases
GCCCGAGACGGTCCCCTCTCGTTTTACGGTGTGCGCCTTAGCCAAGGTCGGGCGCGCCATCACCGCGCCTATCAGCCAGG
CGTGTTGGGCATGGCGCGTC

Downstream 100 bases:

>100_bases
GCAAGGCGATGATCTGCTCCTGTGAGGACGTCACCGTCGACGACATCCGTCACGCGGTGTCCCGGGGCTTCTGCGACGTG
GAGTCGGTGAAGCGCTACAC

Product: pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MPSEALTARSAWAILAHPMRRLPDVPPRGRAITVDLEGESLPAIEGEPVACSLIAAGEPMLARSIKYHRPRGPYCFAGAC
SHCLMRVDGVPNVYACRTPARDGMKLERQNAYPSAKVDIFESIDWFFPKGMDHHEMFAGVPVAEQVMAKVARQLAGLGLL
PKTPAPATAPARTVRTRVAVVGGGAAGLAAARVLTERDVGFLLIERDDALGGRLANGAPEAGGPSLDDIHRISPSSVLTR
ATALGLYDDEAGRFLAVGTWEADAPRLVKVYSERFLLTPGGHPPTLPFENNDLPGVYAGRAASLLLRRYDVAPETAALVG
WGAELHALANLLQERGTKVVAVVDLRDTPPAGTHATAVRGSEPKAHGLRGVSAFSYTREGGGREKVSCDAVLVSVPVSPS
FELARQGGAKVPFDEKRGLFVVETDADGRTQAPDVYAAGDVTGGGTAKDAAAAGRRAAQALVGGLS

Sequences:

>Translated_466_residues
MPSEALTARSAWAILAHPMRRLPDVPPRGRAITVDLEGESLPAIEGEPVACSLIAAGEPMLARSIKYHRPRGPYCFAGAC
SHCLMRVDGVPNVYACRTPARDGMKLERQNAYPSAKVDIFESIDWFFPKGMDHHEMFAGVPVAEQVMAKVARQLAGLGLL
PKTPAPATAPARTVRTRVAVVGGGAAGLAAARVLTERDVGFLLIERDDALGGRLANGAPEAGGPSLDDIHRISPSSVLTR
ATALGLYDDEAGRFLAVGTWEADAPRLVKVYSERFLLTPGGHPPTLPFENNDLPGVYAGRAASLLLRRYDVAPETAALVG
WGAELHALANLLQERGTKVVAVVDLRDTPPAGTHATAVRGSEPKAHGLRGVSAFSYTREGGGREKVSCDAVLVSVPVSPS
FELARQGGAKVPFDEKRGLFVVETDADGRTQAPDVYAAGDVTGGGTAKDAAAAGRRAAQALVGGLS
>Mature_465_residues
PSEALTARSAWAILAHPMRRLPDVPPRGRAITVDLEGESLPAIEGEPVACSLIAAGEPMLARSIKYHRPRGPYCFAGACS
HCLMRVDGVPNVYACRTPARDGMKLERQNAYPSAKVDIFESIDWFFPKGMDHHEMFAGVPVAEQVMAKVARQLAGLGLLP
KTPAPATAPARTVRTRVAVVGGGAAGLAAARVLTERDVGFLLIERDDALGGRLANGAPEAGGPSLDDIHRISPSSVLTRA
TALGLYDDEAGRFLAVGTWEADAPRLVKVYSERFLLTPGGHPPTLPFENNDLPGVYAGRAASLLLRRYDVAPETAALVGW
GAELHALANLLQERGTKVVAVVDLRDTPPAGTHATAVRGSEPKAHGLRGVSAFSYTREGGGREKVSCDAVLVSVPVSPSF
ELARQGGAKVPFDEKRGLFVVETDADGRTQAPDVYAAGDVTGGGTAKDAAAAGRRAAQALVGGLS

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006277 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C; PF07992 Pyr_redox_2 [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 48919; Mature: 48788

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSEALTARSAWAILAHPMRRLPDVPPRGRAITVDLEGESLPAIEGEPVACSLIAAGEPM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCHH
LARSIKYHRPRGPYCFAGACSHCLMRVDGVPNVYACRTPARDGMKLERQNAYPSAKVDIF
HHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCEEHHH
ESIDWFFPKGMDHHEMFAGVPVAEQVMAKVARQLAGLGLLPKTPAPATAPARTVRTRVAV
HHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEE
VGGGAAGLAAARVLTERDVGFLLIERDDALGGRLANGAPEAGGPSLDDIHRISPSSVLTR
EECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHH
ATALGLYDDEAGRFLAVGTWEADAPRLVKVYSERFLLTPGGHPPTLPFENNDLPGVYAGR
HHHCCCEECCCCCEEEEEECCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHH
AASLLLRRYDVAPETAALVGWGAELHALANLLQERGTKVVAVVDLRDTPPAGTHATAVRG
HHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEECC
SEPKAHGLRGVSAFSYTREGGGREKVSCDAVLVSVPVSPSFELARQGGAKVPFDEKRGLF
CCCHHHCCCCCHHHEECCCCCCCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCEE
VVETDADGRTQAPDVYAAGDVTGGGTAKDAAAAGRRAAQALVGGLS
EEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSEALTARSAWAILAHPMRRLPDVPPRGRAITVDLEGESLPAIEGEPVACSLIAAGEPM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCHH
LARSIKYHRPRGPYCFAGACSHCLMRVDGVPNVYACRTPARDGMKLERQNAYPSAKVDIF
HHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCEEHHH
ESIDWFFPKGMDHHEMFAGVPVAEQVMAKVARQLAGLGLLPKTPAPATAPARTVRTRVAV
HHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEE
VGGGAAGLAAARVLTERDVGFLLIERDDALGGRLANGAPEAGGPSLDDIHRISPSSVLTR
EECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHH
ATALGLYDDEAGRFLAVGTWEADAPRLVKVYSERFLLTPGGHPPTLPFENNDLPGVYAGR
HHHCCCEECCCCCEEEEEECCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHH
AASLLLRRYDVAPETAALVGWGAELHALANLLQERGTKVVAVVDLRDTPPAGTHATAVRG
HHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEECC
SEPKAHGLRGVSAFSYTREGGGREKVSCDAVLVSVPVSPSFELARQGGAKVPFDEKRGLF
CCCHHHCCCCCHHHEECCCCCCCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCEE
VVETDADGRTQAPDVYAAGDVTGGGTAKDAAAAGRRAAQALVGGLS
EEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]