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The map label for this gene is cisA [H]

Identifier: 108760467

GI number: 108760467

Start: 2212644

End: 2214191

Strand: Direct

Name: cisA [H]

Synonym: MXAN_1887

Alternate gene names: 108760467

Gene position: 2212644-2214191 (Clockwise)

Preceding gene: 108760217

Following gene: 108761512

Centisome position: 24.21

GC content: 68.41

Gene sequence:

>1548_bases
ATGAGGAAGAGCAAAGCACCGCTCACCGAGGAGAAGCGCTGCGCCGTCTACACGCGCAAGTCCACCGCAGCGGGCCTGGA
GATGGAATTCAACAGCCTCGACGCCCAGCGCGAGTCCTGTGTCGCCTACGTGCAGCGCCAGCCCGGCTGGGTGTTGGTGG
AAGAGAGTTACGACGACGGTGGCTTCACCGGCGCCAACATGGAGCGGCCCGCTTTCCAGCGGCTGCTGCAGGACGTGGAC
GCGAGGCGGGTGGACGTCGTCGTGGTCTACAAGGTGGACCGCCTCTCCCGCAGCCTCCTCGACTTCGCGAAAGTCATGGA
GCGCTTCAATGCGGCGGGCGCCTCCTTCGTCTCGGTGACGCAGAACTTCAGCACGGCGGACGCCATGGGGCGGCTGACGT
TGAACATGCTGATGTCCTTCGCCGAGTTCGAGCGGGAGATGATTTCCGAGCGGACGCGGGACAAGGTGGCCGCCGCGAGG
CGCAAGGGGAAGTGGACGGGAGGACGCGCGCCGCTGGGCTACGAGGTGAAGGACAAGCGCCTCGTGGTGAATGAGTACGA
GGCGGTGGTGGTGCGGGAGGCCTTCGAGTTGTACCTCCAACACCAGCAGGCCTCGGCGGTGGCACGCCTCCTTAATGAGA
CGGGGCGCACGACGAAGCGGTACGAGGCCCAGAGTGGTGCCACGCGCGCGGCTCGGAAGTGGACGACGCAGGATGTGCTG
CGCCTCTTGAGGAGTCCCCTGTACGCAGGCTTCGTGCCGTATGGCGACGAGACGCACCCGGGCGAGCACCCGGCGCTTGT
AGACAGGGCCACCTTCCACCGGGTGCAGGACATGCTGGAGAGCCCCGGCATTCAGTACCACGGGCGTAACCCCGACTACG
TGCTGCGAGGGCTGTTGCGCTGCGGCCTGTGCGGCGAGGCAATGACGCCCGGCAGCACGCGCAAGGGCGAGCGCGAGTAC
CGCTACTACCGCTGCGTCACCCGGGACAAGCAGGGGAAGGAGGGGTGCCGGGCCGCTCCCCTTCCGGCAGCCGCCCTGGA
GGACTTCGTCGTCGCTCAGCTGCGGGAAGTCTCGGTAGGTGACGGCTTCGCTGCCCAGGTGCATGCCCGCCTCACGGCGC
GGCTGGAGGAGAAACACCAGGCCCTGCGCGCCGAGCGCGCGCAGTTGCCGAGGGACTTGGCCAAGCGTGCTGGGGAGTCC
GCGAAGTGGGTGGACTCCCTCTCCAAGTTGGAGGGCCCAGCCCGGCGCCTCGTCGAGGAGAAGCTGACGGCCGCGGAAGA
GGAGGTCGCCGGCATGCGAAAGCGGCTGGCGGAGGTGGAGCGCGCCCTGGACGCCATTGAGGGGGAGAGGGTGGAGGCTG
CGTGGGTGGCCCAGGCCCTGGGGAACTTCGACGCGGTGTGGGACGCCCTCACCTCTACGAATCGGGGGCGCCTGCTGCGG
GCCCTCGTCGGCCGGGTGGTGGTGAACGAGGCGACGGGCAAGGTCGACGTGCATATGGCCCACGTTGGTGAGGCCGCAGT
GACTGGGCGCGAGGAGGTGGCGGCGTGA

Upstream 100 bases:

>100_bases
TGGAGCGGCTGGTGGCCGTCGCGGAGCAGCTCGCCGGGCAGAAGGAGGCCTCGAGCGCCGAGCCGGCACGCCCGACAACG
ACAGCGGGGACGGAGGAACC

Downstream 100 bases:

>100_bases
GCGCGAGCCCCGAGTCTCAGCCGGCGGAGGCGGGCCTCGTCAGCGCGCACTTCCACCGCGTGCGTCGCGCGAAGGTGGTG
CGCCTCCGAGGGGGGGCGCC

Product: resolvase family site-specific recombinase

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MRKSKAPLTEEKRCAVYTRKSTAAGLEMEFNSLDAQRESCVAYVQRQPGWVLVEESYDDGGFTGANMERPAFQRLLQDVD
ARRVDVVVVYKVDRLSRSLLDFAKVMERFNAAGASFVSVTQNFSTADAMGRLTLNMLMSFAEFEREMISERTRDKVAAAR
RKGKWTGGRAPLGYEVKDKRLVVNEYEAVVVREAFELYLQHQQASAVARLLNETGRTTKRYEAQSGATRAARKWTTQDVL
RLLRSPLYAGFVPYGDETHPGEHPALVDRATFHRVQDMLESPGIQYHGRNPDYVLRGLLRCGLCGEAMTPGSTRKGEREY
RYYRCVTRDKQGKEGCRAAPLPAAALEDFVVAQLREVSVGDGFAAQVHARLTARLEEKHQALRAERAQLPRDLAKRAGES
AKWVDSLSKLEGPARRLVEEKLTAAEEEVAGMRKRLAEVERALDAIEGERVEAAWVAQALGNFDAVWDALTSTNRGRLLR
ALVGRVVVNEATGKVDVHMAHVGEAAVTGREEVAA

Sequences:

>Translated_515_residues
MRKSKAPLTEEKRCAVYTRKSTAAGLEMEFNSLDAQRESCVAYVQRQPGWVLVEESYDDGGFTGANMERPAFQRLLQDVD
ARRVDVVVVYKVDRLSRSLLDFAKVMERFNAAGASFVSVTQNFSTADAMGRLTLNMLMSFAEFEREMISERTRDKVAAAR
RKGKWTGGRAPLGYEVKDKRLVVNEYEAVVVREAFELYLQHQQASAVARLLNETGRTTKRYEAQSGATRAARKWTTQDVL
RLLRSPLYAGFVPYGDETHPGEHPALVDRATFHRVQDMLESPGIQYHGRNPDYVLRGLLRCGLCGEAMTPGSTRKGEREY
RYYRCVTRDKQGKEGCRAAPLPAAALEDFVVAQLREVSVGDGFAAQVHARLTARLEEKHQALRAERAQLPRDLAKRAGES
AKWVDSLSKLEGPARRLVEEKLTAAEEEVAGMRKRLAEVERALDAIEGERVEAAWVAQALGNFDAVWDALTSTNRGRLLR
ALVGRVVVNEATGKVDVHMAHVGEAAVTGREEVAA
>Mature_515_residues
MRKSKAPLTEEKRCAVYTRKSTAAGLEMEFNSLDAQRESCVAYVQRQPGWVLVEESYDDGGFTGANMERPAFQRLLQDVD
ARRVDVVVVYKVDRLSRSLLDFAKVMERFNAAGASFVSVTQNFSTADAMGRLTLNMLMSFAEFEREMISERTRDKVAAAR
RKGKWTGGRAPLGYEVKDKRLVVNEYEAVVVREAFELYLQHQQASAVARLLNETGRTTKRYEAQSGATRAARKWTTQDVL
RLLRSPLYAGFVPYGDETHPGEHPALVDRATFHRVQDMLESPGIQYHGRNPDYVLRGLLRCGLCGEAMTPGSTRKGEREY
RYYRCVTRDKQGKEGCRAAPLPAAALEDFVVAQLREVSVGDGFAAQVHARLTARLEEKHQALRAERAQLPRDLAKRAGES
AKWVDSLSKLEGPARRLVEEKLTAAEEEVAGMRKRLAEVERALDAIEGERVEAAWVAQALGNFDAVWDALTSTNRGRLLR
ALVGRVVVNEATGKVDVHMAHVGEAAVTGREEVAA

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787404, Length=110, Percent_Identity=37.2727272727273, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 57465; Mature: 57465

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSKAPLTEEKRCAVYTRKSTAAGLEMEFNSLDAQRESCVAYVQRQPGWVLVEESYDDG
CCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GFTGANMERPAFQRLLQDVDARRVDVVVVYKVDRLSRSLLDFAKVMERFNAAGASFVSVT
CCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QNFSTADAMGRLTLNMLMSFAEFEREMISERTRDKVAAARRKGKWTGGRAPLGYEVKDKR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
LVVNEYEAVVVREAFELYLQHQQASAVARLLNETGRTTKRYEAQSGATRAARKWTTQDVL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCHHHHH
RLLRSPLYAGFVPYGDETHPGEHPALVDRATFHRVQDMLESPGIQYHGRNPDYVLRGLLR
HHHHCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHH
CGLCGEAMTPGSTRKGEREYRYYRCVTRDKQGKEGCRAAPLPAAALEDFVVAQLREVSVG
HCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DGFAAQVHARLTARLEEKHQALRAERAQLPRDLAKRAGESAKWVDSLSKLEGPARRLVEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHH
KLTAAEEEVAGMRKRLAEVERALDAIEGERVEAAWVAQALGNFDAVWDALTSTNRGRLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHH
ALVGRVVVNEATGKVDVHMAHVGEAAVTGREEVAA
HHHHHHHHHCCCCCEEEEEECCCCHHHCCHHHHCC
>Mature Secondary Structure
MRKSKAPLTEEKRCAVYTRKSTAAGLEMEFNSLDAQRESCVAYVQRQPGWVLVEESYDDG
CCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GFTGANMERPAFQRLLQDVDARRVDVVVVYKVDRLSRSLLDFAKVMERFNAAGASFVSVT
CCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QNFSTADAMGRLTLNMLMSFAEFEREMISERTRDKVAAARRKGKWTGGRAPLGYEVKDKR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
LVVNEYEAVVVREAFELYLQHQQASAVARLLNETGRTTKRYEAQSGATRAARKWTTQDVL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCHHHHH
RLLRSPLYAGFVPYGDETHPGEHPALVDRATFHRVQDMLESPGIQYHGRNPDYVLRGLLR
HHHHCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHH
CGLCGEAMTPGSTRKGEREYRYYRCVTRDKQGKEGCRAAPLPAAALEDFVVAQLREVSVG
HCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DGFAAQVHARLTARLEEKHQALRAERAQLPRDLAKRAGESAKWVDSLSKLEGPARRLVEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHH
KLTAAEEEVAGMRKRLAEVERALDAIEGERVEAAWVAQALGNFDAVWDALTSTNRGRLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHH
ALVGRVVVNEATGKVDVHMAHVGEAAVTGREEVAA
HHHHHHHHHCCCCCEEEEEECCCCHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]