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The map label for this gene is rsmB [H]

Identifier: 108760453

GI number: 108760453

Start: 1649130

End: 1650446

Strand: Direct

Name: rsmB [H]

Synonym: MXAN_1401

Alternate gene names: 108760453

Gene position: 1649130-1650446 (Clockwise)

Preceding gene: 108760608

Following gene: 108758146

Centisome position: 18.04

GC content: 72.13

Gene sequence:

>1317_bases
ATGAACGCCCGCGCACTCGCCATCCAGGTCCTCGCGCGTGTCCGCGCGACGGATGCCTACCTCAACGTCGTATTGGACAC
GCAGTTGTCCGAGTCGCCGCCGAAGGACCCGCGCGACGCGGCGCTCGTCACCGAGCTGACCTACGGCGCCACCCGGCGGC
AGCTCGCGCTGGACTACGCGATTACCCGCTTCGCCGACCGCAAGCTGGACGCGCTGGAGGACAAGGTGCTGGCGGCCCTC
CGCATCGGCGCCTACCAGATATTCCACACCCGCGTGCCGGCCCGCGCCGCGGTGGCGGAGACGGTGCAGGCGCTGAAGGA
AGTGGGGCTGACGCGCGCGGCGGGCTTCACCAACGCCATCCTCCGCAAGCTGGCGGCCCTGCCCGCGCCGCCGCTGCCGC
CCGCGTCCGACGTGGCATTGCACCTGTCGGTGCGGGAGAGCCATCCCCAGTGGCTGGTGGAGCGTTGGCTGCGCCAGTTC
GGCCGCGAGCGCGCCGAAGCCATGCTGGTGGCCGACAACCAGGCGCCCGCGGTGGTGGTGCGCGCCAACACCGCGAAGGT
GACGCGCGACGCGCTGCTCGCCCAACTCCAGGAGATGGGCGTGGACGCGAAGGCGACCACCGTGTCGCCGGTGGGCATCA
CGCTGCCGTCCGTGGGCCGCGTGGAGGACGTGTACGGCTACGCGGAGGGCCTGTGGCAGGTGCAGGACGAGGCCGCGCAG
CTCGTGGGCGTCTACGGGGCGATTCCGGAGACGGCGCGCGTGCTGGACGCGTGCGCCGCGCCGGGCGGCAAGTCCTGCCA
CCAGGCGCAGTCACATGACGTGGTGGCGGTGGATCTCCACGCGCACAAGCTGCGGAAGATTGAAGCGGAGGCCCGGCGCC
TGGGCCTGCAGCCGCGCCTGAAGGCCTACGCGCACGACGCCGCGGAGCCCTTCCCGGAGGAGTGGGGAGAGTTCCACGCG
TTCCTGGTGGATGCGCCGTGTTCGGGGCTGGGCACGCTGCGCCGCCACCCGGAGCTGCGCTACCGCCGCAAGGAGGAGGA
CATCTCCCGGCTGGCCACGCTCCAGCGGCGCATCCTGGAGAACTGCCAGGATGCGGTGCCGCCCGGGGGGCTGCTCGTGT
ACGCGGTGTGCACCATGGAGCCGCAGGAGGGGCAGGACCAGGTGGAGATGTTCCTGCGCAGCCACCCGGAGTGGACGGCC
GAGCCACCCGTGCTGCCCGGCCTCAAGCTGCCGATGTCCCAGGCGTACCTGCGCACGCTGCCGGGACCGGAGGGCTTCGA
CGGGTTCTTCGCCGCGCGCCTCCGGAAGCTCTACTGA

Upstream 100 bases:

>100_bases
TGCTGGAGGAGAGCCTCCAGAGCCTCACCCTCTCCAACCTGCCCGCGACGCGGCTCTCGGATGAGCAGCTCGTGGACCTC
TTGACCCGGCTCGACGAAGG

Downstream 100 bases:

>100_bases
CGCTCAGGCGTTCTCGGTGGGCGGCGGCACGTTGGAGGCGGCCTTGAACGCCTCCAGCACCGCGGCGGACGCGCGGTCCA
GGTACTTGCCCTTGCGGATG

Product: ribosomal RNA small subunit methyltransferase B

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNARALAIQVLARVRATDAYLNVVLDTQLSESPPKDPRDAALVTELTYGATRRQLALDYAITRFADRKLDALEDKVLAAL
RIGAYQIFHTRVPARAAVAETVQALKEVGLTRAAGFTNAILRKLAALPAPPLPPASDVALHLSVRESHPQWLVERWLRQF
GRERAEAMLVADNQAPAVVVRANTAKVTRDALLAQLQEMGVDAKATTVSPVGITLPSVGRVEDVYGYAEGLWQVQDEAAQ
LVGVYGAIPETARVLDACAAPGGKSCHQAQSHDVVAVDLHAHKLRKIEAEARRLGLQPRLKAYAHDAAEPFPEEWGEFHA
FLVDAPCSGLGTLRRHPELRYRRKEEDISRLATLQRRILENCQDAVPPGGLLVYAVCTMEPQEGQDQVEMFLRSHPEWTA
EPPVLPGLKLPMSQAYLRTLPGPEGFDGFFAARLRKLY

Sequences:

>Translated_438_residues
MNARALAIQVLARVRATDAYLNVVLDTQLSESPPKDPRDAALVTELTYGATRRQLALDYAITRFADRKLDALEDKVLAAL
RIGAYQIFHTRVPARAAVAETVQALKEVGLTRAAGFTNAILRKLAALPAPPLPPASDVALHLSVRESHPQWLVERWLRQF
GRERAEAMLVADNQAPAVVVRANTAKVTRDALLAQLQEMGVDAKATTVSPVGITLPSVGRVEDVYGYAEGLWQVQDEAAQ
LVGVYGAIPETARVLDACAAPGGKSCHQAQSHDVVAVDLHAHKLRKIEAEARRLGLQPRLKAYAHDAAEPFPEEWGEFHA
FLVDAPCSGLGTLRRHPELRYRRKEEDISRLATLQRRILENCQDAVPPGGLLVYAVCTMEPQEGQDQVEMFLRSHPEWTA
EPPVLPGLKLPMSQAYLRTLPGPEGFDGFFAARLRKLY
>Mature_438_residues
MNARALAIQVLARVRATDAYLNVVLDTQLSESPPKDPRDAALVTELTYGATRRQLALDYAITRFADRKLDALEDKVLAAL
RIGAYQIFHTRVPARAAVAETVQALKEVGLTRAAGFTNAILRKLAALPAPPLPPASDVALHLSVRESHPQWLVERWLRQF
GRERAEAMLVADNQAPAVVVRANTAKVTRDALLAQLQEMGVDAKATTVSPVGITLPSVGRVEDVYGYAEGLWQVQDEAAQ
LVGVYGAIPETARVLDACAAPGGKSCHQAQSHDVVAVDLHAHKLRKIEAEARRLGLQPRLKAYAHDAAEPFPEEWGEFHA
FLVDAPCSGLGTLRRHPELRYRRKEEDISRLATLQRRILENCQDAVPPGGLLVYAVCTMEPQEGQDQVEMFLRSHPEWTA
EPPVLPGLKLPMSQAYLRTLPGPEGFDGFFAARLRKLY

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=325, Percent_Identity=27.0769230769231, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI76150623, Length=325, Percent_Identity=27.0769230769231, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI32698918, Length=168, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI2367212, Length=450, Percent_Identity=32.4444444444444, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87081985, Length=221, Percent_Identity=28.0542986425339, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17536757, Length=322, Percent_Identity=28.2608695652174, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324268, Length=315, Percent_Identity=26.984126984127, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI22024126, Length=335, Percent_Identity=27.1641791044776, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356513, Length=220, Percent_Identity=32.2727272727273, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24668781, Length=220, Percent_Identity=32.2727272727273, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 48175; Mature: 48175

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARALAIQVLARVRATDAYLNVVLDTQLSESPPKDPRDAALVTELTYGATRRQLALDYA
CCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
ITRFADRKLDALEDKVLAALRIGAYQIFHTRVPARAAVAETVQALKEVGLTRAAGFTNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCHHHHHH
LRKLAALPAPPLPPASDVALHLSVRESHPQWLVERWLRQFGRERAEAMLVADNQAPAVVV
HHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEE
RANTAKVTRDALLAQLQEMGVDAKATTVSPVGITLPSVGRVEDVYGYAEGLWQVQDEAAQ
ECCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHH
LVGVYGAIPETARVLDACAAPGGKSCHQAQSHDVVAVDLHAHKLRKIEAEARRLGLQPRL
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCHHH
KAYAHDAAEPFPEEWGEFHAFLVDAPCSGLGTLRRHPELRYRRKEEDISRLATLQRRILE
HHHHHHCCCCCHHHHHCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NCQDAVPPGGLLVYAVCTMEPQEGQDQVEMFLRSHPEWTAEPPVLPGLKLPMSQAYLRTL
HHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHC
PGPEGFDGFFAARLRKLY
CCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNARALAIQVLARVRATDAYLNVVLDTQLSESPPKDPRDAALVTELTYGATRRQLALDYA
CCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
ITRFADRKLDALEDKVLAALRIGAYQIFHTRVPARAAVAETVQALKEVGLTRAAGFTNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCHHHHHH
LRKLAALPAPPLPPASDVALHLSVRESHPQWLVERWLRQFGRERAEAMLVADNQAPAVVV
HHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEE
RANTAKVTRDALLAQLQEMGVDAKATTVSPVGITLPSVGRVEDVYGYAEGLWQVQDEAAQ
ECCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHH
LVGVYGAIPETARVLDACAAPGGKSCHQAQSHDVVAVDLHAHKLRKIEAEARRLGLQPRL
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCHHH
KAYAHDAAEPFPEEWGEFHAFLVDAPCSGLGTLRRHPELRYRRKEEDISRLATLQRRILE
HHHHHHCCCCCHHHHHCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NCQDAVPPGGLLVYAVCTMEPQEGQDQVEMFLRSHPEWTAEPPVLPGLKLPMSQAYLRTL
HHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHC
PGPEGFDGFFAARLRKLY
CCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]