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The map label for this gene is nodV [H]

Identifier: 108760350

GI number: 108760350

Start: 5501650

End: 5503497

Strand: Reverse

Name: nodV [H]

Synonym: MXAN_4444

Alternate gene names: 108760350

Gene position: 5503497-5501650 (Counterclockwise)

Preceding gene: 108763603

Following gene: 108761498

Centisome position: 60.21

GC content: 71.16

Gene sequence:

>1848_bases
ATGAGGCTCTACCAGCAACTCGTCCTGTTCATGCTCGCCGCGACGGTGCTTCCCCTGGCCGCGGTCGGCTTCCTGTTGCT
TTCGCGCGCAGAGGCCGAGCTGGCCGCCCGAATCGACGCGGAGCAGCGCGCGCAGGCGGTCGCCACCGCCGAGTCCGTGG
GCGCCACCATGATGGAGGTGGTGGACGCGCTGGCCCGCTCGGCGGAGCTCATCGACTGGCAGGCCGCGAGCGACGCGGAG
ACGCAGGGCGCGCTGCGGCTGCTTTACGGCCAGTCTCCCGCGGTGAGCGCGGTGCTGAAGCTGGACGCGGAGGGCCGTCC
ACTGGGCGCGCCCGTCTTCCGTGCGCAGGCCATCGACGGGCACCCGGCCTTCTCTCTGGAGTCCCTGGACCGGCTGGTGC
GCTCCATTCCCGTGCAGACGCTGCGAGGCGGCGGCAAGGGCCAGGCGGCGCTGGGCAGCGCGTACGTGCACTCGGACGAG
GGGCGCTCGGCGGTCGCCGTGGCGGTGAAGCTGGCGGAAGGCGAGGGCGCGCCCTTCGCCGTCGCCGAGGTCGTGCTCCA
TCCGCTGGAGGCGGTGCTGCGCAGGCGCCTGGGCGAAGGGCTGGGCCGCATCGACCTGGTGGACGAGGAGCGGCGCGTGC
TCGCCAGCACCGCGTCGGAGCGCCGGGGGCAGGCACTGGCGCCGGAGCTGAGCGCGCACCTGTTGGCCCCGGCGCTGCCG
CTGACGGAGCTGGTGCGCAGCTTCCGCGTGGAGTCACCGGCCCGGCGGGTCAGCGTGGCGCGCGTGCCCCATGGCATGCG
CTTCGACGTGCTGGTGGAAGTGGATGAGTCCACCGCGTTGGCGCCCGTGCACGGCATGCGGCGCACGGTGTTGCTGTCCA
TTGGCGCCACCTTCCTGGTGCTGCTCGGGCTGGGAGCCCTCTTCACGCGCCGCCTCAACGTGCGGCTGGCGGAGGTGGTG
CGCGGCGCTGAGGCCTACGGGCGTGGCGAGCTGGACACGCGCTTGAAGGTCTCCGGCCAGGATGAACTGAGCGAGCTGGC
CACCACCTTCAACCGCATGGGCGAGGAGCTGGAGGCGGCGCGTGCCCGGATGCTGCGCTGGAACGACGATTTGCGCGTTC
GCGTGGAGGAGGCCACCGCGGACTTGAAGGCGGCCCAGGCGCAGTTGGTGGAGGCGCAGAAGCTGGCCGCGGTGGGGCAG
CTCGGCGCGGGCGTGGCGCACGAAATCAACAACCCGCTGGCGGGCATCCTCGGCAACGTGCAGTTGCTGATGCTCGACCG
AGGCGCCGCCGACCCGGACTTGGAGTCGCTGCGGAAAATCGAGCAGAGCGCCAAGCGCTGCAAGGAAATCACCCAGAACC
TGCTGCGCTTCTCCCAGCAGCGCGAGCGCGCGGAGCTGCGGCCGGTGGACCTCAACGCGGTGGTGCGTGACGCGCTCAGC
CTCACGGAGCACCAGCTTCGCGGCGATGGCGTGGCGCTCACCAGCGTGCTGGGAGACGGGCTCGCGCGAGTGCGTGCCGA
CCCGGGGCACTTGTCGCAGGTGGTGCTGGCGCTGGTGTCCAACGCGCGCACCGCGATGCTGAATTCACCCGAGAAGCGGC
TCACCCTGCGCACGGGCGAAGTCGGCGGCTTCGGCTTCCTGGAGGTGGAGGACACGGGGAAGGGGATTGCCCCCAACGTC
CGCTCCCGCATCTTCGAGCCCTTCTTCACGACGAAGGACGTGTGGTCCAACGTGGGGTTGGGGCTCAGCGTGGCCTGGCG
TGTGGTGACGGAAGCGGGCGGGAGCATCGAAGTCCGCTCGGAAGTCGAGCAGGGCAGTTGCTTCACCGTGAAGCTGCCGA
AGGCGTGA

Upstream 100 bases:

>100_bases
TGGCGCGGCGCGCCGCGGACATGAAGAAGCGCGCCAAGGCGATTGCGGGCTCTGTCTTCCTGCGCAGTGACCAGGAGCGG
GTGGTACGCTCCGTGGCCGG

Downstream 100 bases:

>100_bases
GGCCCCTTGGGGGGCCTGTGATAGCTAACGAGGCTGCCCATGGCTGATTCCCGCCCATCGCGCCGTCAGGCGCCTTTCTT
CATTGGCCTCGTGCTGATTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MRLYQQLVLFMLAATVLPLAAVGFLLLSRAEAELAARIDAEQRAQAVATAESVGATMMEVVDALARSAELIDWQAASDAE
TQGALRLLYGQSPAVSAVLKLDAEGRPLGAPVFRAQAIDGHPAFSLESLDRLVRSIPVQTLRGGGKGQAALGSAYVHSDE
GRSAVAVAVKLAEGEGAPFAVAEVVLHPLEAVLRRRLGEGLGRIDLVDEERRVLASTASERRGQALAPELSAHLLAPALP
LTELVRSFRVESPARRVSVARVPHGMRFDVLVEVDESTALAPVHGMRRTVLLSIGATFLVLLGLGALFTRRLNVRLAEVV
RGAEAYGRGELDTRLKVSGQDELSELATTFNRMGEELEAARARMLRWNDDLRVRVEEATADLKAAQAQLVEAQKLAAVGQ
LGAGVAHEINNPLAGILGNVQLLMLDRGAADPDLESLRKIEQSAKRCKEITQNLLRFSQQRERAELRPVDLNAVVRDALS
LTEHQLRGDGVALTSVLGDGLARVRADPGHLSQVVLALVSNARTAMLNSPEKRLTLRTGEVGGFGFLEVEDTGKGIAPNV
RSRIFEPFFTTKDVWSNVGLGLSVAWRVVTEAGGSIEVRSEVEQGSCFTVKLPKA

Sequences:

>Translated_615_residues
MRLYQQLVLFMLAATVLPLAAVGFLLLSRAEAELAARIDAEQRAQAVATAESVGATMMEVVDALARSAELIDWQAASDAE
TQGALRLLYGQSPAVSAVLKLDAEGRPLGAPVFRAQAIDGHPAFSLESLDRLVRSIPVQTLRGGGKGQAALGSAYVHSDE
GRSAVAVAVKLAEGEGAPFAVAEVVLHPLEAVLRRRLGEGLGRIDLVDEERRVLASTASERRGQALAPELSAHLLAPALP
LTELVRSFRVESPARRVSVARVPHGMRFDVLVEVDESTALAPVHGMRRTVLLSIGATFLVLLGLGALFTRRLNVRLAEVV
RGAEAYGRGELDTRLKVSGQDELSELATTFNRMGEELEAARARMLRWNDDLRVRVEEATADLKAAQAQLVEAQKLAAVGQ
LGAGVAHEINNPLAGILGNVQLLMLDRGAADPDLESLRKIEQSAKRCKEITQNLLRFSQQRERAELRPVDLNAVVRDALS
LTEHQLRGDGVALTSVLGDGLARVRADPGHLSQVVLALVSNARTAMLNSPEKRLTLRTGEVGGFGFLEVEDTGKGIAPNV
RSRIFEPFFTTKDVWSNVGLGLSVAWRVVTEAGGSIEVRSEVEQGSCFTVKLPKA
>Mature_615_residues
MRLYQQLVLFMLAATVLPLAAVGFLLLSRAEAELAARIDAEQRAQAVATAESVGATMMEVVDALARSAELIDWQAASDAE
TQGALRLLYGQSPAVSAVLKLDAEGRPLGAPVFRAQAIDGHPAFSLESLDRLVRSIPVQTLRGGGKGQAALGSAYVHSDE
GRSAVAVAVKLAEGEGAPFAVAEVVLHPLEAVLRRRLGEGLGRIDLVDEERRVLASTASERRGQALAPELSAHLLAPALP
LTELVRSFRVESPARRVSVARVPHGMRFDVLVEVDESTALAPVHGMRRTVLLSIGATFLVLLGLGALFTRRLNVRLAEVV
RGAEAYGRGELDTRLKVSGQDELSELATTFNRMGEELEAARARMLRWNDDLRVRVEEATADLKAAQAQLVEAQKLAAVGQ
LGAGVAHEINNPLAGILGNVQLLMLDRGAADPDLESLRKIEQSAKRCKEITQNLLRFSQQRERAELRPVDLNAVVRDALS
LTEHQLRGDGVALTSVLGDGLARVRADPGHLSQVVLALVSNARTAMLNSPEKRLTLRTGEVGGFGFLEVEDTGKGIAPNV
RSRIFEPFFTTKDVWSNVGLGLSVAWRVVTEAGGSIEVRSEVEQGSCFTVKLPKA

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=34.9344978165939, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788549, Length=307, Percent_Identity=31.5960912052117, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI87081816, Length=346, Percent_Identity=27.7456647398844, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1789149, Length=344, Percent_Identity=27.6162790697674, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=30.8641975308642, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI48994928, Length=222, Percent_Identity=27.9279279279279, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=320, Percent_Identity=22.5, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66016; Mature: 66016

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYQQLVLFMLAATVLPLAAVGFLLLSRAEAELAARIDAEQRAQAVATAESVGATMMEV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VDALARSAELIDWQAASDAETQGALRLLYGQSPAVSAVLKLDAEGRPLGAPVFRAQAIDG
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHEEECCCCCCCCCCHHEEEECCC
HPAFSLESLDRLVRSIPVQTLRGGGKGQAALGSAYVHSDEGRSAVAVAVKLAEGEGAPFA
CCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHCCCEEECCCCCCEEEEEEEEECCCCCCHH
VAEVVLHPLEAVLRRRLGEGLGRIDLVDEERRVLASTASERRGQALAPELSAHLLAPALP
HHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
LTELVRSFRVESPARRVSVARVPHGMRFDVLVEVDESTALAPVHGMRRTVLLSIGATFLV
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
LLGLGALFTRRLNVRLAEVVRGAEAYGRGELDTRLKVSGQDELSELATTFNRMGEELEAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
RARMLRWNDDLRVRVEEATADLKAAQAQLVEAQKLAAVGQLGAGVAHEINNPLAGILGNV
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCE
QLLMLDRGAADPDLESLRKIEQSAKRCKEITQNLLRFSQQRERAELRPVDLNAVVRDALS
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTEHQLRGDGVALTSVLGDGLARVRADPGHLSQVVLALVSNARTAMLNSPEKRLTLRTGE
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCHHEEEEECC
VGGFGFLEVEDTGKGIAPNVRSRIFEPFFTTKDVWSNVGLGLSVAWRVVTEAGGSIEVRS
CCCEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEEE
EVEQGSCFTVKLPKA
CCCCCCEEEEECCCC
>Mature Secondary Structure
MRLYQQLVLFMLAATVLPLAAVGFLLLSRAEAELAARIDAEQRAQAVATAESVGATMMEV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VDALARSAELIDWQAASDAETQGALRLLYGQSPAVSAVLKLDAEGRPLGAPVFRAQAIDG
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHEEECCCCCCCCCCHHEEEECCC
HPAFSLESLDRLVRSIPVQTLRGGGKGQAALGSAYVHSDEGRSAVAVAVKLAEGEGAPFA
CCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHCCCEEECCCCCCEEEEEEEEECCCCCCHH
VAEVVLHPLEAVLRRRLGEGLGRIDLVDEERRVLASTASERRGQALAPELSAHLLAPALP
HHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
LTELVRSFRVESPARRVSVARVPHGMRFDVLVEVDESTALAPVHGMRRTVLLSIGATFLV
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
LLGLGALFTRRLNVRLAEVVRGAEAYGRGELDTRLKVSGQDELSELATTFNRMGEELEAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
RARMLRWNDDLRVRVEEATADLKAAQAQLVEAQKLAAVGQLGAGVAHEINNPLAGILGNV
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCE
QLLMLDRGAADPDLESLRKIEQSAKRCKEITQNLLRFSQQRERAELRPVDLNAVVRDALS
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTEHQLRGDGVALTSVLGDGLARVRADPGHLSQVVLALVSNARTAMLNSPEKRLTLRTGE
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCHHEEEEECC
VGGFGFLEVEDTGKGIAPNVRSRIFEPFFTTKDVWSNVGLGLSVAWRVVTEAGGSIEVRS
CCCEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEEE
EVEQGSCFTVKLPKA
CCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]