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The map label for this gene is yajO [H]

Identifier: 108760229

GI number: 108760229

Start: 2468285

End: 2469403

Strand: Reverse

Name: yajO [H]

Synonym: MXAN_2137

Alternate gene names: 108760229

Gene position: 2469403-2468285 (Counterclockwise)

Preceding gene: 108761710

Following gene: 108757288

Centisome position: 27.02

GC content: 65.86

Gene sequence:

>1119_bases
ATGTCGACGCGAATCATCGATTCCTTGGCGAAGTACCACCTGCTCGGCCAGACGGGCCTTCGGGTGAGCCCGCTGGCATT
GGGCACCATGAACTTCGGTACCGACTGGGGCTGGGGCATCACCAGTGAGGACGCACACCGCTTGCTGACACGCTATCTGG
AAGCGGGCGGTAACTTCATTGATACAGCGGATGCGTACACCTCCGGCTCCAGCGAGCGGATCATCGGCGACTACTTCGCG
AAGCATGGCGGGAGGGAACGGGCGGTCATCGCCACCAAGTTCTCCGCCAACCTGTCTCCGGGGGATCCGAATGCGGGCGG
AAACAGCCGCAAGCACATCTACGCCGCCCTCGAAGGCTCGCTGCGCCGCCTCAAGATGAGCTACGTGGACGTGTACTGGC
TGCACGTATGGGACGGCCTGACACCCGTGGAGGAAGTGATGGGGACGCTGACCGGCCTCGTGCGCGAGGGCAAGGTGCGC
TACATCGGCTTCTCCGACGTGCCTGCCTGGTACTTCGCGCGCGCACAGACATTGGCGGAGCGCAACCACTGGGAAAAGGT
CGCCGCGCTGCAACTGGAGTACTCGCTCGCTGAACGCAATGTCGAGCGCGAGCACCTCCCCGCCGCGCTGGCCATGGGGG
CCGCCCTCACTCCGTGGAGCCCCCTGGCCGGGGGCCTCCTCACCGGGAGGTACACCCGCGACGGAAACCAGCCGAAGGGT
GACGGGCGCGCCCATGCACTGCTCGCCAGCGGAAACCCCGTGGCGGACAAGTTCCTGCAAGAGCGCCCCTGGGCCATTGT
CGAGGAGCTCGTCGCTGTGGCGAAAGAGGTGGAGCGCTCGCCCGCCCAGGTGGCGCTCAACTGGGTGGCGACGCGTCCGG
CCGTCGTGTCCACCATCATCGGCGCGAGCAGGCTGGAGCAGTTGGAGGACAACCTCCATGCGCTGGACTTCAAGCTACCG
CACGAACTCTCCGCGAGACTGGACGCCGCGAGTCGCCCCGAGCTCTTCAATCCGTACGTGTTCTTCGAAAACCCCTTCTT
CACGAAGGGAATGCTCGCGGGCAATACCACGGTGAGCGCGGAGCCGAGCGGGTTCCGGGGACCGCTCCAGCCCCGGTAG

Upstream 100 bases:

>100_bases
CAATCAGGCGCAAGAAGCGGGCTGCCTTCATGCAGGCGCTCTTCTATCCGTAACAGGGCGATGGGGAGCACACCCCATCA
CCACAGATGGAGAGCACCCC

Downstream 100 bases:

>100_bases
ACCATGCAACGGTTTGAGGCAACCCATAGCTGTTTGGGCTGCCAATCCCTTTGCATTGAAAAAGTGTGGGCGTCGCCAGC
GCGGCGCCCGGCTCACGAGG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSTRIIDSLAKYHLLGQTGLRVSPLALGTMNFGTDWGWGITSEDAHRLLTRYLEAGGNFIDTADAYTSGSSERIIGDYFA
KHGGRERAVIATKFSANLSPGDPNAGGNSRKHIYAALEGSLRRLKMSYVDVYWLHVWDGLTPVEEVMGTLTGLVREGKVR
YIGFSDVPAWYFARAQTLAERNHWEKVAALQLEYSLAERNVEREHLPAALAMGAALTPWSPLAGGLLTGRYTRDGNQPKG
DGRAHALLASGNPVADKFLQERPWAIVEELVAVAKEVERSPAQVALNWVATRPAVVSTIIGASRLEQLEDNLHALDFKLP
HELSARLDAASRPELFNPYVFFENPFFTKGMLAGNTTVSAEPSGFRGPLQPR

Sequences:

>Translated_372_residues
MSTRIIDSLAKYHLLGQTGLRVSPLALGTMNFGTDWGWGITSEDAHRLLTRYLEAGGNFIDTADAYTSGSSERIIGDYFA
KHGGRERAVIATKFSANLSPGDPNAGGNSRKHIYAALEGSLRRLKMSYVDVYWLHVWDGLTPVEEVMGTLTGLVREGKVR
YIGFSDVPAWYFARAQTLAERNHWEKVAALQLEYSLAERNVEREHLPAALAMGAALTPWSPLAGGLLTGRYTRDGNQPKG
DGRAHALLASGNPVADKFLQERPWAIVEELVAVAKEVERSPAQVALNWVATRPAVVSTIIGASRLEQLEDNLHALDFKLP
HELSARLDAASRPELFNPYVFFENPFFTKGMLAGNTTVSAEPSGFRGPLQPR
>Mature_371_residues
STRIIDSLAKYHLLGQTGLRVSPLALGTMNFGTDWGWGITSEDAHRLLTRYLEAGGNFIDTADAYTSGSSERIIGDYFAK
HGGRERAVIATKFSANLSPGDPNAGGNSRKHIYAALEGSLRRLKMSYVDVYWLHVWDGLTPVEEVMGTLTGLVREGKVRY
IGFSDVPAWYFARAQTLAERNHWEKVAALQLEYSLAERNVEREHLPAALAMGAALTPWSPLAGGLLTGRYTRDGNQPKGD
GRAHALLASGNPVADKFLQERPWAIVEELVAVAKEVERSPAQVALNWVATRPAVVSTIIGASRLEQLEDNLHALDFKLPH
ELSARLDAASRPELFNPYVFFENPFFTKGMLAGNTTVSAEPSGFRGPLQPR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=335, Percent_Identity=32.8358208955224, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI27436969, Length=327, Percent_Identity=33.0275229357798, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4504825, Length=329, Percent_Identity=32.8267477203647, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI27436971, Length=314, Percent_Identity=33.7579617834395, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI223718702, Length=282, Percent_Identity=34.7517730496454, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI41327764, Length=310, Percent_Identity=33.8709677419355, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI41152114, Length=287, Percent_Identity=33.4494773519164, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI223718708, Length=159, Percent_Identity=36.4779874213836, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081735, Length=338, Percent_Identity=39.0532544378698, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=31.5340909090909, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789375, Length=320, Percent_Identity=34.0625, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=30.2469135802469, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788081, Length=279, Percent_Identity=30.1075268817204, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI48994888, Length=300, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=364, Percent_Identity=31.5934065934066, Blast_Score=169, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6319958, Length=318, Percent_Identity=30.5031446540881, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=29.2834890965732, Blast_Score=145, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6325169, Length=346, Percent_Identity=30.635838150289, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322615, Length=273, Percent_Identity=29.3040293040293, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321052, Length=181, Percent_Identity=33.7016574585635, Blast_Score=109, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24640980, Length=326, Percent_Identity=26.9938650306748, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI45549126, Length=326, Percent_Identity=26.9938650306748, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24646155, Length=162, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40845; Mature: 40713

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRIIDSLAKYHLLGQTGLRVSPLALGTMNFGTDWGWGITSEDAHRLLTRYLEAGGNFI
CCHHHHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
DTADAYTSGSSERIIGDYFAKHGGRERAVIATKFSANLSPGDPNAGGNSRKHIYAALEGS
ECCHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEHHHH
LRRLKMSYVDVYWLHVWDGLTPVEEVMGTLTGLVREGKVRYIGFSDVPAWYFARAQTLAE
HHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
RNHWEKVAALQLEYSLAERNVEREHLPAALAMGAALTPWSPLAGGLLTGRYTRDGNQPKG
HHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCCCCCHHHCCCEECCEECCCCCCCC
DGRAHALLASGNPVADKFLQERPWAIVEELVAVAKEVERSPAQVALNWVATRPAVVSTII
CCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHEEHHHHHCCHHHHHHHH
GASRLEQLEDNLHALDFKLPHELSARLDAASRPELFNPYVFFENPFFTKGMLAGNTTVSA
HHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCEEECCCEECC
EPSGFRGPLQPR
CCCCCCCCCCCC
>Mature Secondary Structure 
STRIIDSLAKYHLLGQTGLRVSPLALGTMNFGTDWGWGITSEDAHRLLTRYLEAGGNFI
CHHHHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
DTADAYTSGSSERIIGDYFAKHGGRERAVIATKFSANLSPGDPNAGGNSRKHIYAALEGS
ECCHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEHHHH
LRRLKMSYVDVYWLHVWDGLTPVEEVMGTLTGLVREGKVRYIGFSDVPAWYFARAQTLAE
HHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
RNHWEKVAALQLEYSLAERNVEREHLPAALAMGAALTPWSPLAGGLLTGRYTRDGNQPKG
HHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCCCCCHHHCCCEECCEECCCCCCCC
DGRAHALLASGNPVADKFLQERPWAIVEELVAVAKEVERSPAQVALNWVATRPAVVSTII
CCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHEEHHHHHCCHHHHHHHH
GASRLEQLEDNLHALDFKLPHELSARLDAASRPELFNPYVFFENPFFTKGMLAGNTTVSA
HHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCEEECCCEECC
EPSGFRGPLQPR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]