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The map label for this gene is lgrC [H]

Identifier: 108760219

GI number: 108760219

Start: 3254843

End: 3259510

Strand: Reverse

Name: lgrC [H]

Synonym: MXAN_2796

Alternate gene names: 108760219

Gene position: 3259510-3254843 (Counterclockwise)

Preceding gene: 108762113

Following gene: 108760476

Centisome position: 35.66

GC content: 70.12

Gene sequence:

>4668_bases
ATGAGCGCGGCTCCGGAGTCGCCCAACTGTTTCATCATTGGCGAGGGCACCCTCGTCGTTCCCTGTGCACAAGCCCTCAC
CGAGCGCGGCGTCCGGATTCTCGGGCTCGTCACGCGCGAGCCCGCGCTCCAGAAGTGGGCGGAGGAGCAGGGCGTGCCGC
ACGTGCCGCCCGGCGAGCAGGCCCTGCCCTTCCTGTCCCAGGCGCCTTTCGACTGGCTCTTCAGCATCGTCAACCTGAGC
ATGGTGAAGGACGAAATCCTGCGCCTGCCCCGGCGCATGGCCATCAACTTCCATGACGGCCCGCTGCCCCGCTACGCCGG
ACTCAATGTCACGTCGTGGGCGCTGCTGAACCGGGAGCCTCAGCACGGCGTCACGTGGCACGAGATGACGAAGGGCGCGG
ACGAGGGCCGCATCCTCAAGCAGCGCCTCTTCGACATCGCCCCCGGTGAGACGGCCTTCAGCCTCAACGCCCGCTGCTAC
ACGCTGGGCATGGAGACCTTCGCGGAGCTCGCGGAAGAGCTGGTCGCGGGCACGTCCGAGGCGAAGGAGCAGGACTTCGC
GCAGCGCAGCTACTTCGGCCTCGCGCAGCGTCCGGAGGCCGCGGGCGTCGTCGACCTCCACGGAGACGTGGACGTGGCGC
ACGCGCTGGTATCGGCGCTCGACTACGGCGGCTACCCCAACCCGCTGTCCTTCGCGAAGGTCTGGCTGGGCAACGGGCCC
ATCGCCATCTCCGAGGCCCGCCGCGCCGAGCCGGCATCCGAGTCCGCCCCGGGCACCGTGCTCGACATCGAGGGTGACGC
GCTGACGGTGGCGCTCCAGGGCGGAGACCTCACGCTGAAGGGCCCCAAGGGGCTGTGCGGCGCGCCGCTGTCATGGGCCG
ACGTGCTCGGCGCTCGAATGCTTGCCCGGGGTGACGCCCTGCCCGCCGCCGCTCCGGAGCTGCGCGCCCGGCTGACCGAG
GTGGGCACGCAGGCGGGCAAGGCGGAGTCGTTCTTCCTCCGTCGCCTGGAGACGCTCGCGCCACCGGACCTGTCCTTCCT
GGGCGGCAGCTCCAAGGACGTGGGGACGCACACACTGAAGTTCGAGGCCAGCGACCTTACCCCAGGCTGGGTCACGGACC
TGCCTCCCGAGGAGCGGCTGCTCTTCACCGCCATGGCTTTCCTGGCGCGCCTGTCCCCCGAGCCCCGCTTCGACGTCGGC
TACGCGGATGCGTCCACGCGCGCCCACATCGAAGGCGTGGAAGGCTTCTTCGCCTCGCAGCTCCCGCTGCGCATCGAGCT
GCCGATGAAGGATGCGCCGGAGCAGGCCGCGGGTGCCTTCCGCAAGGCGCTGACGCAACTGCGCGACAAGGGCGTGCTCG
CGCGCGACGCCCTGGGCCGCTCCGCGCAGCTCTCCAACCTCCAGCGCCACGGCGGCGAAGTGGCGTATCCCGTCGCGCTG
CGCATCGGAGCGGCGAACCCCGCCGTGGGTGGCGCGGCGCTCGTCATTGACGTGGACGCGCAGGGCCGACACGCCCACCT
GCACTTTGATGCCACGCGCGTGGACAAGGCCCGCGTGGACGACGTGGCGCGGCAGCTCAACGCGTTCCTCGCCTCGCTCC
GGGACGCGCCGGGCAAGGCGGTGGGCGAGCATGACCTGCTGGGCGCGGAGGAGCGCCAGTTGCTGGCCCGGTGGAACGAC
ACGCGGCGGGACTTCCCCCGCGACGCCACCCTGGCCTCGCTCTTCCAGGCCCAGGCGCGGCGCACGCCGGACGACACCGC
GCTCATCTGCCGGGGCACCTCGCTGACCTACCGCGAACTGGACGCGCGCGCCGAGGTGCTCGCACGGCACCTGCGCGGCG
CGGGCGTGGGCCGCGACGTGCGCGTGGGCATCTTCATGGAGCGCTCGCTGGAGATGATGGTGGGCGTGCTGGCCACGCAC
AAGGCGGGCGGCTGCTACGTGCCGTTGGACCCGGCCTATCCCGCCGAGCGCATCGCTTTCATGGAGGAGGACGCGGGCTG
CCACCTGGTGCTCACCCAGGAGCGGCTGCTGTCGCGCGTGCCGTCCGCGGCGAAGGCCGTGCTCGCGGTGGACCAGCAGT
GGGAGCGCATCGCCGCCGCGCCGGAGGCCCAGACGCCGCCGGCCACGCCGGACAGCCTGGCCTACGTCATCTACACCTCG
GGCAGCACGGGCAAGCCCAAGGGGGTGATGATTGAACACCGCAACGTCGTGAACTTCGGCGTTGGCATGGACGAGCGCTT
GGGCACGGAGCGCGGCACCTGGCTGGCGGTGACGAGCCTCAACTTCGACATCTCCGTGCTGGAGCTGCTCTGGACGCTCA
CGCGCGGCTTCACGGTGGTGCTGCACGCGGAGCGGCACGACACGGCGCAGGCCGGCAAGCACGCCTCGCGCGCCATGGAG
TTCAGTCTCTTCTACTTCTCCAGTGATGAAGGCGAGCGTCCCGAGGGACGCTATGACCTGCTCATGGAGAGCGCGCGCTT
CGCGGACACGAACGGCTTCTGCGCCGTGTGGACGCCGGAGCGGCACTTCCACGCGTTCGGCGGACTCTTCCCCAACCCGG
CGGTGACGTCGGCCGCGCTGGCGGCGGTGACGCGCAACGTGCAGCTTCGCGCCGGCAGCCTCGTGTCGCCGCTGCACCCC
ACGCTGCGCATCGCCGAGGACTGGTCCGTGGTGGACAACATCTCCCACGGCCGCGTGGGCATTTCGTTCGCCGCGGGCTG
GCAGCCCAACGACTTCGCGCTGCGTCCGGAGACCTTCCCGGACCGCAAGCGCATCATGTTCCAGCAGATTGAAGACGTGC
GCCGGCTATGGCGTGGCGAGGCGCTGGAGACGAAGAGCGGCACGGGCCACACCGTGAAGCTGCGCACCCTGCCCCGCCCG
GTGCAGAAAGAGCTGCCCATCTGGGTCACCACCGCGGGCAACCCGGAGACCTTCGAGGAAGCGGCGCGCGCGGGCTGCCA
CGTCCTCACCCACCTGCTGGGCCAGTCGGTGGAAGAGGTGGCGCAGAAGATTGCCCTCTACCGGGAGACGTGGGCCAAGG
CCGGCCACCCCGGCAAGGGCACCGTGTCGCTGATGCTGCACACCTTCGTCGGTGACTCCGAGGCTTCCGTGAAGGAGGTC
GTCCGCGAGCCGATGAAGTCGTACCTCAGGTCGTCGGTGGGCCTCATCAAGGAGGCGGCCTGGAGCTTCCCGGCCTTCAA
GGCGCAGACGACGCTGGCCAACGGCAACTTCGGCACCGACCACCTGTCCGCCGAGGAGATGGACGCGCTTCTCGACTTCT
CCTTCGAGCGCTACTTCCAGTCCTCCGGCCTGTTCGGCAGCGTGGATGCGTGCGTCGCGCTCGTGGACCGGCTCAAGGGA
CTGGACGTGGACGAGATTGCCTGCCTCGTGGACTTCGGTGTGCCCACGGAGCTGGTGATGAAGCACCTGCCGCTGCTGGC
CGAGGTGCGCCAGCGCGCCAACTCGGGCGTGGGCCAGCCGGGCGCCGAGCCCGAACTCGACGGCTCCATCCCCGCGCTGA
TGGAGCGTCACGCGGTGACGCATCTCCAGTGCACGCCGTCCCAGGCGAGCATGCTCCTGGCCGAGGAGCGCTCGCGCGAG
GGCCTCAAGCGGCTGAAGAAGATGATGGTGGGCGGCGAGGCCTTCCCCGTCCCGCTGGCGCGACAGCTCTCCGAGACGGT
GTCCGGCGACGTCATCAACATGTACGGCCCCACCGAGACGACCATCTGGTCCTCCACGCACCCGGTGAAGAACGTGGGCG
AAGGCGTCCCTATCGGTACGCCCATCGCGAACACGCAGTTCTACATCCTGGATGCGCAGCAGCGTCCGCTGCCCATTGGC
GCGGCGGGTGAGCTGTACATCGGCGGCGAGGGCGTGGTGCGGGGCTACCACCACCGTCCGGAGCTGGACCGCGAGCGCTT
CGTGCCGGACCCGTTCTCCTCCCAGCCAGGCGCGCAGATGTACCGCACCGGTGATGCCGCGCGGTGGAGGCACGACGGTC
TGGTGGAGTACATCGGCCGGCTGGACCACCAGGTGAAGGTGCGCGGCTTCCGCATCGAGCTGGGCGAAATCGAATCCCGG
CTGGGCGAACACCCCGCGGTGCGGGAGACGGTTGTCATCGTCCGCGAGGACATCCCGGGCGACAAGCGGCTGGTGGCCTA
CCTCATCGCGAAGCCGGGCGAGCCGCCCGCGGCGGACGCGCTGCGCGAGTTTCTGCGCACGAGGCTGCCCGAGTACATGG
TGCCGCAGTCCTTCGTGACGCTGAGCACCTTCCCCCAGACGCCGAACAAGAAGGTGGACCGCAAGGCCCTGCCACCTCCG
GAGCAGGCGCAGGCGCGCGGTGAGCTGGTCCGGCCGGAAGGCGAGACGGAGGCGCTGATTGCCAGCATCTGGCAGGACGT
GCTCAAGCTCGACAAGGTCGGCGTGGAGGACAAATTCGTCGACCTGGGCGGCCACTCGCTGCTGATGGTGCAGGTGCTGG
AGAAGCTCAAGGCCCAGGTGGAGAAACCCCTCACGCTGGTGGACCTGTTCCGCTACCCCACCATCCGCACCCTCTCCGGG
TTCCTGTCGGGTGACAGCGGCGAGGAAGAAGCGCTCAAGGAAGTCGCGGCGCGCGGTGAGGCCCGGGCCGCGGCTCGCCG
GGCGATGCAGCAGCGCCGCCGCCGGTAG

Upstream 100 bases:

>100_bases
GCCGAGCTTTTGAAGCATCCCCCCGCGCTCGCCGACGCCCGGCAGGGCCTGGGCTTGTGAGCGGGGAACACCCGAATCGC
AGCAACGCAGGAGGCACTGA

Downstream 100 bases:

>100_bases
ACGTCCATTGCCGCCGGAGCCGTACGCGTCGACCGGAGCGGTGCGAGGTGTCTCGCGCCGCTCCGGCGGGCCCGCCGTTA
CGCCTTGCCTCGGCGGGCCA

Product: non-ribosomal peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1555; Mature: 1554

Protein sequence:

>1555_residues
MSAAPESPNCFIIGEGTLVVPCAQALTERGVRILGLVTREPALQKWAEEQGVPHVPPGEQALPFLSQAPFDWLFSIVNLS
MVKDEILRLPRRMAINFHDGPLPRYAGLNVTSWALLNREPQHGVTWHEMTKGADEGRILKQRLFDIAPGETAFSLNARCY
TLGMETFAELAEELVAGTSEAKEQDFAQRSYFGLAQRPEAAGVVDLHGDVDVAHALVSALDYGGYPNPLSFAKVWLGNGP
IAISEARRAEPASESAPGTVLDIEGDALTVALQGGDLTLKGPKGLCGAPLSWADVLGARMLARGDALPAAAPELRARLTE
VGTQAGKAESFFLRRLETLAPPDLSFLGGSSKDVGTHTLKFEASDLTPGWVTDLPPEERLLFTAMAFLARLSPEPRFDVG
YADASTRAHIEGVEGFFASQLPLRIELPMKDAPEQAAGAFRKALTQLRDKGVLARDALGRSAQLSNLQRHGGEVAYPVAL
RIGAANPAVGGAALVIDVDAQGRHAHLHFDATRVDKARVDDVARQLNAFLASLRDAPGKAVGEHDLLGAEERQLLARWND
TRRDFPRDATLASLFQAQARRTPDDTALICRGTSLTYRELDARAEVLARHLRGAGVGRDVRVGIFMERSLEMMVGVLATH
KAGGCYVPLDPAYPAERIAFMEEDAGCHLVLTQERLLSRVPSAAKAVLAVDQQWERIAAAPEAQTPPATPDSLAYVIYTS
GSTGKPKGVMIEHRNVVNFGVGMDERLGTERGTWLAVTSLNFDISVLELLWTLTRGFTVVLHAERHDTAQAGKHASRAME
FSLFYFSSDEGERPEGRYDLLMESARFADTNGFCAVWTPERHFHAFGGLFPNPAVTSAALAAVTRNVQLRAGSLVSPLHP
TLRIAEDWSVVDNISHGRVGISFAAGWQPNDFALRPETFPDRKRIMFQQIEDVRRLWRGEALETKSGTGHTVKLRTLPRP
VQKELPIWVTTAGNPETFEEAARAGCHVLTHLLGQSVEEVAQKIALYRETWAKAGHPGKGTVSLMLHTFVGDSEASVKEV
VREPMKSYLRSSVGLIKEAAWSFPAFKAQTTLANGNFGTDHLSAEEMDALLDFSFERYFQSSGLFGSVDACVALVDRLKG
LDVDEIACLVDFGVPTELVMKHLPLLAEVRQRANSGVGQPGAEPELDGSIPALMERHAVTHLQCTPSQASMLLAEERSRE
GLKRLKKMMVGGEAFPVPLARQLSETVSGDVINMYGPTETTIWSSTHPVKNVGEGVPIGTPIANTQFYILDAQQRPLPIG
AAGELYIGGEGVVRGYHHRPELDRERFVPDPFSSQPGAQMYRTGDAARWRHDGLVEYIGRLDHQVKVRGFRIELGEIESR
LGEHPAVRETVVIVREDIPGDKRLVAYLIAKPGEPPAADALREFLRTRLPEYMVPQSFVTLSTFPQTPNKKVDRKALPPP
EQAQARGELVRPEGETEALIASIWQDVLKLDKVGVEDKFVDLGGHSLLMVQVLEKLKAQVEKPLTLVDLFRYPTIRTLSG
FLSGDSGEEEALKEVAARGEARAAARRAMQQRRRR

Sequences:

>Translated_1555_residues
MSAAPESPNCFIIGEGTLVVPCAQALTERGVRILGLVTREPALQKWAEEQGVPHVPPGEQALPFLSQAPFDWLFSIVNLS
MVKDEILRLPRRMAINFHDGPLPRYAGLNVTSWALLNREPQHGVTWHEMTKGADEGRILKQRLFDIAPGETAFSLNARCY
TLGMETFAELAEELVAGTSEAKEQDFAQRSYFGLAQRPEAAGVVDLHGDVDVAHALVSALDYGGYPNPLSFAKVWLGNGP
IAISEARRAEPASESAPGTVLDIEGDALTVALQGGDLTLKGPKGLCGAPLSWADVLGARMLARGDALPAAAPELRARLTE
VGTQAGKAESFFLRRLETLAPPDLSFLGGSSKDVGTHTLKFEASDLTPGWVTDLPPEERLLFTAMAFLARLSPEPRFDVG
YADASTRAHIEGVEGFFASQLPLRIELPMKDAPEQAAGAFRKALTQLRDKGVLARDALGRSAQLSNLQRHGGEVAYPVAL
RIGAANPAVGGAALVIDVDAQGRHAHLHFDATRVDKARVDDVARQLNAFLASLRDAPGKAVGEHDLLGAEERQLLARWND
TRRDFPRDATLASLFQAQARRTPDDTALICRGTSLTYRELDARAEVLARHLRGAGVGRDVRVGIFMERSLEMMVGVLATH
KAGGCYVPLDPAYPAERIAFMEEDAGCHLVLTQERLLSRVPSAAKAVLAVDQQWERIAAAPEAQTPPATPDSLAYVIYTS
GSTGKPKGVMIEHRNVVNFGVGMDERLGTERGTWLAVTSLNFDISVLELLWTLTRGFTVVLHAERHDTAQAGKHASRAME
FSLFYFSSDEGERPEGRYDLLMESARFADTNGFCAVWTPERHFHAFGGLFPNPAVTSAALAAVTRNVQLRAGSLVSPLHP
TLRIAEDWSVVDNISHGRVGISFAAGWQPNDFALRPETFPDRKRIMFQQIEDVRRLWRGEALETKSGTGHTVKLRTLPRP
VQKELPIWVTTAGNPETFEEAARAGCHVLTHLLGQSVEEVAQKIALYRETWAKAGHPGKGTVSLMLHTFVGDSEASVKEV
VREPMKSYLRSSVGLIKEAAWSFPAFKAQTTLANGNFGTDHLSAEEMDALLDFSFERYFQSSGLFGSVDACVALVDRLKG
LDVDEIACLVDFGVPTELVMKHLPLLAEVRQRANSGVGQPGAEPELDGSIPALMERHAVTHLQCTPSQASMLLAEERSRE
GLKRLKKMMVGGEAFPVPLARQLSETVSGDVINMYGPTETTIWSSTHPVKNVGEGVPIGTPIANTQFYILDAQQRPLPIG
AAGELYIGGEGVVRGYHHRPELDRERFVPDPFSSQPGAQMYRTGDAARWRHDGLVEYIGRLDHQVKVRGFRIELGEIESR
LGEHPAVRETVVIVREDIPGDKRLVAYLIAKPGEPPAADALREFLRTRLPEYMVPQSFVTLSTFPQTPNKKVDRKALPPP
EQAQARGELVRPEGETEALIASIWQDVLKLDKVGVEDKFVDLGGHSLLMVQVLEKLKAQVEKPLTLVDLFRYPTIRTLSG
FLSGDSGEEEALKEVAARGEARAAARRAMQQRRRR
>Mature_1554_residues
SAAPESPNCFIIGEGTLVVPCAQALTERGVRILGLVTREPALQKWAEEQGVPHVPPGEQALPFLSQAPFDWLFSIVNLSM
VKDEILRLPRRMAINFHDGPLPRYAGLNVTSWALLNREPQHGVTWHEMTKGADEGRILKQRLFDIAPGETAFSLNARCYT
LGMETFAELAEELVAGTSEAKEQDFAQRSYFGLAQRPEAAGVVDLHGDVDVAHALVSALDYGGYPNPLSFAKVWLGNGPI
AISEARRAEPASESAPGTVLDIEGDALTVALQGGDLTLKGPKGLCGAPLSWADVLGARMLARGDALPAAAPELRARLTEV
GTQAGKAESFFLRRLETLAPPDLSFLGGSSKDVGTHTLKFEASDLTPGWVTDLPPEERLLFTAMAFLARLSPEPRFDVGY
ADASTRAHIEGVEGFFASQLPLRIELPMKDAPEQAAGAFRKALTQLRDKGVLARDALGRSAQLSNLQRHGGEVAYPVALR
IGAANPAVGGAALVIDVDAQGRHAHLHFDATRVDKARVDDVARQLNAFLASLRDAPGKAVGEHDLLGAEERQLLARWNDT
RRDFPRDATLASLFQAQARRTPDDTALICRGTSLTYRELDARAEVLARHLRGAGVGRDVRVGIFMERSLEMMVGVLATHK
AGGCYVPLDPAYPAERIAFMEEDAGCHLVLTQERLLSRVPSAAKAVLAVDQQWERIAAAPEAQTPPATPDSLAYVIYTSG
STGKPKGVMIEHRNVVNFGVGMDERLGTERGTWLAVTSLNFDISVLELLWTLTRGFTVVLHAERHDTAQAGKHASRAMEF
SLFYFSSDEGERPEGRYDLLMESARFADTNGFCAVWTPERHFHAFGGLFPNPAVTSAALAAVTRNVQLRAGSLVSPLHPT
LRIAEDWSVVDNISHGRVGISFAAGWQPNDFALRPETFPDRKRIMFQQIEDVRRLWRGEALETKSGTGHTVKLRTLPRPV
QKELPIWVTTAGNPETFEEAARAGCHVLTHLLGQSVEEVAQKIALYRETWAKAGHPGKGTVSLMLHTFVGDSEASVKEVV
REPMKSYLRSSVGLIKEAAWSFPAFKAQTTLANGNFGTDHLSAEEMDALLDFSFERYFQSSGLFGSVDACVALVDRLKGL
DVDEIACLVDFGVPTELVMKHLPLLAEVRQRANSGVGQPGAEPELDGSIPALMERHAVTHLQCTPSQASMLLAEERSREG
LKRLKKMMVGGEAFPVPLARQLSETVSGDVINMYGPTETTIWSSTHPVKNVGEGVPIGTPIANTQFYILDAQQRPLPIGA
AGELYIGGEGVVRGYHHRPELDRERFVPDPFSSQPGAQMYRTGDAARWRHDGLVEYIGRLDHQVKVRGFRIELGEIESRL
GEHPAVRETVVIVREDIPGDKRLVAYLIAKPGEPPAADALREFLRTRLPEYMVPQSFVTLSTFPQTPNKKVDRKALPPPE
QAQARGELVRPEGETEALIASIWQDVLKLDKVGVEDKFVDLGGHSLLMVQVLEKLKAQVEKPLTLVDLFRYPTIRTLSGF
LSGDSGEEEALKEVAARGEARAAARRAMQQRRRR

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI38505220, Length=282, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=7e-16,
Organism=Homo sapiens, GI45580730, Length=350, Percent_Identity=24.2857142857143, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI187761345, Length=256, Percent_Identity=24.21875, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI187761343, Length=256, Percent_Identity=24.21875, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI122937307, Length=268, Percent_Identity=24.6268656716418, Blast_Score=72, Evalue=6e-12,
Organism=Homo sapiens, GI28416953, Length=142, Percent_Identity=32.3943661971831, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI42544132, Length=276, Percent_Identity=22.8260869565217, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI156151445, Length=234, Percent_Identity=24.7863247863248, Blast_Score=69, Evalue=4e-11,
Organism=Homo sapiens, GI157311624, Length=275, Percent_Identity=23.2727272727273, Blast_Score=69, Evalue=5e-11,
Organism=Homo sapiens, GI157311622, Length=275, Percent_Identity=23.2727272727273, Blast_Score=69, Evalue=5e-11,
Organism=Escherichia coli, GI1786801, Length=383, Percent_Identity=37.3368146214099, Blast_Score=213, Evalue=7e-56,
Organism=Escherichia coli, GI1786810, Length=286, Percent_Identity=28.3216783216783, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI1788589, Length=301, Percent_Identity=27.5747508305648, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI145693145, Length=277, Percent_Identity=25.2707581227437, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790505, Length=280, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788107, Length=217, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17556356, Length=326, Percent_Identity=28.5276073619632, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=336, Percent_Identity=24.702380952381, Blast_Score=91, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319591, Length=447, Percent_Identity=28.1879194630872, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319699, Length=278, Percent_Identity=24.4604316546763, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648676, Length=329, Percent_Identity=30.0911854103343, Blast_Score=128, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24582852, Length=281, Percent_Identity=26.3345195729537, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581924, Length=275, Percent_Identity=26.5454545454545, Blast_Score=78, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 170024; Mature: 169893

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPESPNCFIIGEGTLVVPCAQALTERGVRILGLVTREPALQKWAEEQGVPHVPPGEQ
CCCCCCCCCEEEEECCEEEEHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHH
ALPFLSQAPFDWLFSIVNLSMVKDEILRLPRRMAINFHDGPLPRYAGLNVTSWALLNREP
HCCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCEEEHHCCCCC
QHGVTWHEMTKGADEGRILKQRLFDIAPGETAFSLNARCYTLGMETFAELAEELVAGTSE
CCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEECHHHHHHHHHHHHCCCCH
AKEQDFAQRSYFGLAQRPEAAGVVDLHGDVDVAHALVSALDYGGYPNPLSFAKVWLGNGP
HHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHEEECCCC
IAISEARRAEPASESAPGTVLDIEGDALTVALQGGDLTLKGPKGLCGAPLSWADVLGARM
EEECHHHCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHHHHH
LARGDALPAAAPELRARLTEVGTQAGKAESFFLRRLETLAPPDLSFLGGSSKDVGTHTLK
HHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCEEEE
FEASDLTPGWVTDLPPEERLLFTAMAFLARLSPEPRFDVGYADASTRAHIEGVEGFFASQ
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHCC
LPLRIELPMKDAPEQAAGAFRKALTQLRDKGVLARDALGRSAQLSNLQRHGGEVAYPVAL
CCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEE
RIGAANPAVGGAALVIDVDAQGRHAHLHFDATRVDKARVDDVARQLNAFLASLRDAPGKA
EECCCCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGEHDLLGAEERQLLARWNDTRRDFPRDATLASLFQAQARRTPDDTALICRGTSLTYREL
CCCHHCCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
DARAEVLARHLRGAGVGRDVRVGIFMERSLEMMVGVLATHKAGGCYVPLDPAYPAERIAF
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHE
MEEDAGCHLVLTQERLLSRVPSAAKAVLAVDQQWERIAAAPEAQTPPATPDSLAYVIYTS
EECCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
GSTGKPKGVMIEHRNVVNFGVGMDERLGTERGTWLAVTSLNFDISVLELLWTLTRGFTVV
CCCCCCCCEEEECCCEEEECCCCHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEE
LHAERHDTAQAGKHASRAMEFSLFYFSSDEGERPEGRYDLLMESARFADTNGFCAVWTPE
EEECCCCHHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCC
RHFHAFGGLFPNPAVTSAALAAVTRNVQLRAGSLVSPLHPTLRIAEDWSVVDNISHGRVG
HHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEEECCHHHHHCCCCCCEE
ISFAAGWQPNDFALRPETFPDRKRIMFQQIEDVRRLWRGEALETKSGTGHTVKLRTLPRP
EEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
VQKELPIWVTTAGNPETFEEAARAGCHVLTHLLGQSVEEVAQKIALYRETWAKAGHPGKG
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TVSLMLHTFVGDSEASVKEVVREPMKSYLRSSVGLIKEAAWSFPAFKAQTTLANGNFGTD
CCEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
HLSAEEMDALLDFSFERYFQSSGLFGSVDACVALVDRLKGLDVDEIACLVDFGVPTELVM
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHEEEECCCCHHHHH
KHLPLLAEVRQRANSGVGQPGAEPELDGSIPALMERHAVTHLQCTPSQASMLLAEERSRE
HHCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHH
GLKRLKKMMVGGEAFPVPLARQLSETVSGDVINMYGPTETTIWSSTHPVKNVGEGVPIGT
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEECCCCCHHHHCCCCCCCC
PIANTQFYILDAQQRPLPIGAAGELYIGGEGVVRGYHHRPELDRERFVPDPFSSQPGAQM
CCCCCEEEEEECCCCCCCCCCCCEEEECCCHHCCCCCCCCCCCHHHCCCCCCCCCCCCHH
YRTGDAARWRHDGLVEYIGRLDHQVKVRGFRIELGEIESRLGEHPAVRETVVIVREDIPG
HCCCCCHHHHHCCHHHHHHHCCCEEEEEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCCC
DKRLVAYLIAKPGEPPAADALREFLRTRLPEYMVPQSFVTLSTFPQTPNKKVDRKALPPP
CHHEEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
EQAQARGELVRPEGETEALIASIWQDVLKLDKVGVEDKFVDLGGHSLLMVQVLEKLKAQV
HHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHH
EKPLTLVDLFRYPTIRTLSGFLSGDSGEEEALKEVAARGEARAAARRAMQQRRRR
HCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAAPESPNCFIIGEGTLVVPCAQALTERGVRILGLVTREPALQKWAEEQGVPHVPPGEQ
CCCCCCCCEEEEECCEEEEHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHH
ALPFLSQAPFDWLFSIVNLSMVKDEILRLPRRMAINFHDGPLPRYAGLNVTSWALLNREP
HCCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCEEEHHCCCCC
QHGVTWHEMTKGADEGRILKQRLFDIAPGETAFSLNARCYTLGMETFAELAEELVAGTSE
CCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEECHHHHHHHHHHHHCCCCH
AKEQDFAQRSYFGLAQRPEAAGVVDLHGDVDVAHALVSALDYGGYPNPLSFAKVWLGNGP
HHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHEEECCCC
IAISEARRAEPASESAPGTVLDIEGDALTVALQGGDLTLKGPKGLCGAPLSWADVLGARM
EEECHHHCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHHHHH
LARGDALPAAAPELRARLTEVGTQAGKAESFFLRRLETLAPPDLSFLGGSSKDVGTHTLK
HHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCEEEE
FEASDLTPGWVTDLPPEERLLFTAMAFLARLSPEPRFDVGYADASTRAHIEGVEGFFASQ
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHCC
LPLRIELPMKDAPEQAAGAFRKALTQLRDKGVLARDALGRSAQLSNLQRHGGEVAYPVAL
CCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEE
RIGAANPAVGGAALVIDVDAQGRHAHLHFDATRVDKARVDDVARQLNAFLASLRDAPGKA
EECCCCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGEHDLLGAEERQLLARWNDTRRDFPRDATLASLFQAQARRTPDDTALICRGTSLTYREL
CCCHHCCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
DARAEVLARHLRGAGVGRDVRVGIFMERSLEMMVGVLATHKAGGCYVPLDPAYPAERIAF
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHE
MEEDAGCHLVLTQERLLSRVPSAAKAVLAVDQQWERIAAAPEAQTPPATPDSLAYVIYTS
EECCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
GSTGKPKGVMIEHRNVVNFGVGMDERLGTERGTWLAVTSLNFDISVLELLWTLTRGFTVV
CCCCCCCCEEEECCCEEEECCCCHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEE
LHAERHDTAQAGKHASRAMEFSLFYFSSDEGERPEGRYDLLMESARFADTNGFCAVWTPE
EEECCCCHHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCC
RHFHAFGGLFPNPAVTSAALAAVTRNVQLRAGSLVSPLHPTLRIAEDWSVVDNISHGRVG
HHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEEECCHHHHHCCCCCCEE
ISFAAGWQPNDFALRPETFPDRKRIMFQQIEDVRRLWRGEALETKSGTGHTVKLRTLPRP
EEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
VQKELPIWVTTAGNPETFEEAARAGCHVLTHLLGQSVEEVAQKIALYRETWAKAGHPGKG
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TVSLMLHTFVGDSEASVKEVVREPMKSYLRSSVGLIKEAAWSFPAFKAQTTLANGNFGTD
CCEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
HLSAEEMDALLDFSFERYFQSSGLFGSVDACVALVDRLKGLDVDEIACLVDFGVPTELVM
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHEEEECCCCHHHHH
KHLPLLAEVRQRANSGVGQPGAEPELDGSIPALMERHAVTHLQCTPSQASMLLAEERSRE
HHCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHH
GLKRLKKMMVGGEAFPVPLARQLSETVSGDVINMYGPTETTIWSSTHPVKNVGEGVPIGT
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEECCCCCHHHHCCCCCCCC
PIANTQFYILDAQQRPLPIGAAGELYIGGEGVVRGYHHRPELDRERFVPDPFSSQPGAQM
CCCCCEEEEEECCCCCCCCCCCCEEEECCCHHCCCCCCCCCCCHHHCCCCCCCCCCCCHH
YRTGDAARWRHDGLVEYIGRLDHQVKVRGFRIELGEIESRLGEHPAVRETVVIVREDIPG
HCCCCCHHHHHCCHHHHHHHCCCEEEEEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCCC
DKRLVAYLIAKPGEPPAADALREFLRTRLPEYMVPQSFVTLSTFPQTPNKKVDRKALPPP
CHHEEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
EQAQARGELVRPEGETEALIASIWQDVLKLDKVGVEDKFVDLGGHSLLMVQVLEKLKAQV
HHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHH
EKPLTLVDLFRYPTIRTLSGFLSGDSGEEEALKEVAARGEARAAARRAMQQRRRR
HCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA