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The map label for this gene is xerC

Identifier: 108760213

GI number: 108760213

Start: 3535483

End: 3536385

Strand: Direct

Name: xerC

Synonym: MXAN_3010

Alternate gene names: 108760213

Gene position: 3535483-3536385 (Clockwise)

Preceding gene: 108757715

Following gene: 108759779

Centisome position: 38.68

GC content: 66.56

Gene sequence:

>903_bases
ATGACGAGCCTGTCGCCGCTGCTGGAGAAGTTCCGCGCCCACCTGGAGGACGAGAAGGGCTCGTCCCCGCACACGGTGCG
CAACTACCTCATCGACCTGGTGGACTTCGAGCGCTACCTGGTGGAGCGAATGAAGCTGTCGCTCCTGTCGGGGACGCACG
CGGCGATTCGTGGCTACCTGGGCACGTTGAGCACGGACCACGCCCCGGCGAGCCGGGCGCGGCGGCTGGCGAGCATCAAG
TCGTTCTACAAGTACCTCGTTCGGCAGAAGCTGTTGCCCGCGAGCCCCGCGAAGCTGGTGAAGAGCCCGAAGCTGCCGAA
GACGCTGCCCAAGGTGCTGCCGGTGGAGGAGGTTTTCGCCATCCTGGACATGCCCGACGTGAAGACGGTGCTCGGGCTGC
GGGACAGGGCGATTCTGGAGCTGCTCTACGGCGGCGGCCTGCGTATCAGTGAGTTGTGCGGGTTGGACCTGCTGGACATC
GACCGCAGCGGGCGAATCGTCAGGGTGATGGGCAAGGGGAGCAAGGAGCGGCTCGTGCCCGTGAACGCGCAGTCCATCCG
AGCGTTGGAGGCGTACCTCGCACGGCGGGGGGAGCTGCTGGCCACGATTCGGAAGGACCAGGCGCCAGAGGCGATGTTCC
TCAACTTCCGGGGAGGACGCCTGACGCCGAGGAGCATCGCGCGGCACCTGGATACATACGTGCTGAAGTGCGCGCTGACG
CGGAAGGTGAGCCCGCATGCCATGCGTCACTCCTTCGCCACGCACCTGCTGGGCGGGGGCGCGGACATCCGCAGCATCCA
GGAGCTGCTGGGCCATTCAAGCTTGTCCACCACGCAGCGGTATACCCAGGTGACGTGGGAGCAGCTCCAGCAGGTCTACG
ACTCCGCGCATCCGCGGGCGTGA

Upstream 100 bases:

>100_bases
CGGCTCCGGCGGCGGCAGCGCCTGCCGCGGCTCCGGCCAAGGCGCCGTAGGCCCACCGCGAATCTTGCCAGGATTTCTCC
GGCCCGTAGGCTCGTCCTCG

Downstream 100 bases:

>100_bases
GTGCTCGGCGACCAGGCGACGCCGCGTGACGGGGACCGTAATTGCCATCGCGAACCTGTCCTGTGTTGCGCCCGTCCTCG
CCGCGCTCTGCCTCGTCCAT

Product: phage integrase family site specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTSLSPLLEKFRAHLEDEKGSSPHTVRNYLIDLVDFERYLVERMKLSLLSGTHAAIRGYLGTLSTDHAPASRARRLASIK
SFYKYLVRQKLLPASPAKLVKSPKLPKTLPKVLPVEEVFAILDMPDVKTVLGLRDRAILELLYGGGLRISELCGLDLLDI
DRSGRIVRVMGKGSKERLVPVNAQSIRALEAYLARRGELLATIRKDQAPEAMFLNFRGGRLTPRSIARHLDTYVLKCALT
RKVSPHAMRHSFATHLLGGGADIRSIQELLGHSSLSTTQRYTQVTWEQLQQVYDSAHPRA

Sequences:

>Translated_300_residues
MTSLSPLLEKFRAHLEDEKGSSPHTVRNYLIDLVDFERYLVERMKLSLLSGTHAAIRGYLGTLSTDHAPASRARRLASIK
SFYKYLVRQKLLPASPAKLVKSPKLPKTLPKVLPVEEVFAILDMPDVKTVLGLRDRAILELLYGGGLRISELCGLDLLDI
DRSGRIVRVMGKGSKERLVPVNAQSIRALEAYLARRGELLATIRKDQAPEAMFLNFRGGRLTPRSIARHLDTYVLKCALT
RKVSPHAMRHSFATHLLGGGADIRSIQELLGHSSLSTTQRYTQVTWEQLQQVYDSAHPRA
>Mature_299_residues
TSLSPLLEKFRAHLEDEKGSSPHTVRNYLIDLVDFERYLVERMKLSLLSGTHAAIRGYLGTLSTDHAPASRARRLASIKS
FYKYLVRQKLLPASPAKLVKSPKLPKTLPKVLPVEEVFAILDMPDVKTVLGLRDRAILELLYGGGLRISELCGLDLLDID
RSGRIVRVMGKGSKERLVPVNAQSIRALEAYLARRGELLATIRKDQAPEAMFLNFRGGRLTPRSIARHLDTYVLKCALTR
KVSPHAMRHSFATHLLGGGADIRSIQELLGHSSLSTTQRYTQVTWEQLQQVYDSAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=305, Percent_Identity=39.672131147541, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=39.8648648648649, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1790768, Length=153, Percent_Identity=32.6797385620915, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_MYXXA (P59818)

Other databases:

- EMBL:   AY204472
- ProteinModelPortal:   P59818
- SMR:   P59818
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 33583; Mature: 33451

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: ACT_SITE 148-148 ACT_SITE 172-172 ACT_SITE 246-246 ACT_SITE 249-249 ACT_SITE 272-272 ACT_SITE 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLSPLLEKFRAHLEDEKGSSPHTVRNYLIDLVDFERYLVERMKLSLLSGTHAAIRGYL
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GTLSTDHAPASRARRLASIKSFYKYLVRQKLLPASPAKLVKSPKLPKTLPKVLPVEEVFA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHCCHHHHHH
ILDMPDVKTVLGLRDRAILELLYGGGLRISELCGLDLLDIDRSGRIVRVMGKGSKERLVP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEECCCCCEEEEECCCCCCCEEC
VNAQSIRALEAYLARRGELLATIRKDQAPEAMFLNFRGGRLTPRSIARHLDTYVLKCALT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
RKVSPHAMRHSFATHLLGGGADIRSIQELLGHSSLSTTQRYTQVTWEQLQQVYDSAHPRA
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSLSPLLEKFRAHLEDEKGSSPHTVRNYLIDLVDFERYLVERMKLSLLSGTHAAIRGYL
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GTLSTDHAPASRARRLASIKSFYKYLVRQKLLPASPAKLVKSPKLPKTLPKVLPVEEVFA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHCCHHHHHH
ILDMPDVKTVLGLRDRAILELLYGGGLRISELCGLDLLDIDRSGRIVRVMGKGSKERLVP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEECCCCCEEEEECCCCCCCEEC
VNAQSIRALEAYLARRGELLATIRKDQAPEAMFLNFRGGRLTPRSIARHLDTYVLKCALT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
RKVSPHAMRHSFATHLLGGGADIRSIQELLGHSSLSTTQRYTQVTWEQLQQVYDSAHPRA
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12828649