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The map label for this gene is 108760201

Identifier: 108760201

GI number: 108760201

Start: 6745078

End: 6747069

Strand: Direct

Name: 108760201

Synonym: MXAN_5417

Alternate gene names: NA

Gene position: 6745078-6747069 (Clockwise)

Preceding gene: 108762795

Following gene: 108761234

Centisome position: 73.8

GC content: 71.64

Gene sequence:

>1992_bases
ATGTGGAAACTCCATCTCGTCCCGCTTCTGTGTCTGCTCACCACCACTACCAGTTGCACCGAGCCGCCCGCTCCCCTCGC
CCATGCGGTCCCGCGCCAGCGTCCCATTGCGAACCGATACATCGTCGTGCTCCGCCCGGAGGCCCGCGCCGCATCCCAGG
GGCCCCAGAAGACGCGGGAGCACGTGTCGAACCTCGCCAAGACGCATGGCGCGAAGGTGCTCCACACCTATGCGCATGCG
CTCCAGGGCTTCTCGGCGGAGCTGGACGACGCGCGCTTGGAGGCGCTGCGCGCCGACGAGCGCGTGGCCTTCATCGAGCA
GGATGCATGGGTGCGCCCGCTCGTCACGGCGGAGACGGTGGCGTGGGGCCTGGACCGCGTGGACCAGGAGGACCTGCCCC
TGGATGGTCTCTATCGCCCGGCGCTGAGCGGCGCGGGTGTCCACGCGTACGTGCTCGACACGGGCATCCGCTCCACGCAT
GCCGAGTTCCAGGGACGCCTGGGCGAGGGCTTCGACGCGGTGGACCCCGACGGTGGCGCGGAGGACTGCGACGGGCACGG
CACCCACGTCGCGGGCATCCTCGGTGGCACGACCTGGGGCGTGGCCCGGGCCGTGACGCTGCATCCCGTGCGCATCCTGA
ACTGTGACGGAGAAGGCCCCCTGTCGGGCATCATCGCCGGCATCGACTGGGTCGCCGCCCATCACCAGTCCCCCGCGGTC
GCCAACCTGAGCATCGGGCTGGAGGTCTCCGAGGCGCTGGACCAGGCGGTCCGCAACGTCGTGGCCGCCGGCGTCACCGC
CGTGGTGGCCGCGGGCAACTTCGGCGTCAGCGCGTGCGACGAGTCTCCTGCTCGCGCGGCGGAAGCCCTCACCGTGGGCG
CCACCAACGTGGAGGACTCCCGCGCGTCATTCTCGAATCACGGCCCCTGCGTCGACCTGTACGCGCCGGGCGAGGACATT
CGCTCCGCCGGCATCGCCAACGACACGGCAAGCGAGGTCTTCTCCGGTACCTCCATGGCCACCCCTCACGTCGCCGGCGC
CGCCGCGCTCTACCTGGAGATCCACCCCACCGCCACCCCGGCCCAGGTGATGGACGCGCTCGCGGGCGCCGCCATCTCGG
GCCGCGTGAAGAACGCCGGGCCGGGCTCCCCCGACCTGCTGCTCCAGGCGGGCTTCCGCCGCTCGACGGGGGACGTCCAC
CGCCCCTGGGCACACGTCGCAACGCCCTTCCCCTGGAGCACCGTGCGCGCCACCTCACGTGTGCGGGTGCTCGCCTGGGA
CGATGCGGCGGTCCGGCGCGTGGACCTCTGGGTCAACGGCCTCCTGCGCGCCAGTGACGACACCCACCCCTTCGAGCTCG
ACTGGGACACCCGGGAAGAGCTCAACGGCCCGGCCACCCTGGAGGTCCGCGCCTACGACACCGCGCTCAAGGCCTGGCGC
GCCGCGCCCATGACGGTGACGGTGCGCAACCCCGACATCGCCGACTTCGATTCGACGCTCCAGGCGCCCCGCTGCGCCAC
CCTCGCGTTCGCGTGCGACACCGGCGTGCTCGTGCGCGGCATGGGCACCGTGGGGCCAGAGCGCCATGCGCCCAACACGC
TCGGCGCGAGCTGTGCGGATGGCATCGATGGCACCTACCTCATCACCGCGACGCTGGAGGGGCTGCGCGTCTCCAGCCAG
GACGGCGGCCCTCTCACCGCCGGCAAGCCGGTGAAACTCACCGCGACCGCCTTCGGCTTCTTGCCCTTCCTGGAAGCGGT
GGACCTCTTCCATGCGCCCGACGCGCGCAGCCCCCAATGGACACATGTCGCCCGGCTCCCGCTCGAAGAGACAGGGGCGC
AGGAGCTATCCACCACCTTCACGCTGCCAGAGGGAGGGCTCCAGGCGATTCGCGGCATCCTCGGCACCCATCCCACCCCG
GTCAGCTGCGCCCCGGGAGCCTGGACAGACCACGACGACCTCGTCTTCCCCGTGGCCCCCTCGAGTCGCTGA

Upstream 100 bases:

>100_bases
AATCCCGACACCCGTGGCGTCCAAGCGGGCGCACCATGACGCCGCCCTCGCACAGGCATGACGCCTCCGCGAGAGGCGTC
CCACCTCAGGCCCACGCCCC

Downstream 100 bases:

>100_bases
AGGCCCACGGCAGCGCGCCGTTGTCGCCAGTGGGAGCGCGTCGTGTCCCCGCGTCGCGGGAAGCGTGAGCTTGCGAGGCC
CCGGGCTCAGATGTAGCCAC

Product: S8A family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MWKLHLVPLLCLLTTTTSCTEPPAPLAHAVPRQRPIANRYIVVLRPEARAASQGPQKTREHVSNLAKTHGAKVLHTYAHA
LQGFSAELDDARLEALRADERVAFIEQDAWVRPLVTAETVAWGLDRVDQEDLPLDGLYRPALSGAGVHAYVLDTGIRSTH
AEFQGRLGEGFDAVDPDGGAEDCDGHGTHVAGILGGTTWGVARAVTLHPVRILNCDGEGPLSGIIAGIDWVAAHHQSPAV
ANLSIGLEVSEALDQAVRNVVAAGVTAVVAAGNFGVSACDESPARAAEALTVGATNVEDSRASFSNHGPCVDLYAPGEDI
RSAGIANDTASEVFSGTSMATPHVAGAAALYLEIHPTATPAQVMDALAGAAISGRVKNAGPGSPDLLLQAGFRRSTGDVH
RPWAHVATPFPWSTVRATSRVRVLAWDDAAVRRVDLWVNGLLRASDDTHPFELDWDTREELNGPATLEVRAYDTALKAWR
AAPMTVTVRNPDIADFDSTLQAPRCATLAFACDTGVLVRGMGTVGPERHAPNTLGASCADGIDGTYLITATLEGLRVSSQ
DGGPLTAGKPVKLTATAFGFLPFLEAVDLFHAPDARSPQWTHVARLPLEETGAQELSTTFTLPEGGLQAIRGILGTHPTP
VSCAPGAWTDHDDLVFPVAPSSR

Sequences:

>Translated_663_residues
MWKLHLVPLLCLLTTTTSCTEPPAPLAHAVPRQRPIANRYIVVLRPEARAASQGPQKTREHVSNLAKTHGAKVLHTYAHA
LQGFSAELDDARLEALRADERVAFIEQDAWVRPLVTAETVAWGLDRVDQEDLPLDGLYRPALSGAGVHAYVLDTGIRSTH
AEFQGRLGEGFDAVDPDGGAEDCDGHGTHVAGILGGTTWGVARAVTLHPVRILNCDGEGPLSGIIAGIDWVAAHHQSPAV
ANLSIGLEVSEALDQAVRNVVAAGVTAVVAAGNFGVSACDESPARAAEALTVGATNVEDSRASFSNHGPCVDLYAPGEDI
RSAGIANDTASEVFSGTSMATPHVAGAAALYLEIHPTATPAQVMDALAGAAISGRVKNAGPGSPDLLLQAGFRRSTGDVH
RPWAHVATPFPWSTVRATSRVRVLAWDDAAVRRVDLWVNGLLRASDDTHPFELDWDTREELNGPATLEVRAYDTALKAWR
AAPMTVTVRNPDIADFDSTLQAPRCATLAFACDTGVLVRGMGTVGPERHAPNTLGASCADGIDGTYLITATLEGLRVSSQ
DGGPLTAGKPVKLTATAFGFLPFLEAVDLFHAPDARSPQWTHVARLPLEETGAQELSTTFTLPEGGLQAIRGILGTHPTP
VSCAPGAWTDHDDLVFPVAPSSR
>Mature_663_residues
MWKLHLVPLLCLLTTTTSCTEPPAPLAHAVPRQRPIANRYIVVLRPEARAASQGPQKTREHVSNLAKTHGAKVLHTYAHA
LQGFSAELDDARLEALRADERVAFIEQDAWVRPLVTAETVAWGLDRVDQEDLPLDGLYRPALSGAGVHAYVLDTGIRSTH
AEFQGRLGEGFDAVDPDGGAEDCDGHGTHVAGILGGTTWGVARAVTLHPVRILNCDGEGPLSGIIAGIDWVAAHHQSPAV
ANLSIGLEVSEALDQAVRNVVAAGVTAVVAAGNFGVSACDESPARAAEALTVGATNVEDSRASFSNHGPCVDLYAPGEDI
RSAGIANDTASEVFSGTSMATPHVAGAAALYLEIHPTATPAQVMDALAGAAISGRVKNAGPGSPDLLLQAGFRRSTGDVH
RPWAHVATPFPWSTVRATSRVRVLAWDDAAVRRVDLWVNGLLRASDDTHPFELDWDTREELNGPATLEVRAYDTALKAWR
AAPMTVTVRNPDIADFDSTLQAPRCATLAFACDTGVLVRGMGTVGPERHAPNTLGASCADGIDGTYLITATLEGLRVSSQ
DGGPLTAGKPVKLTATAFGFLPFLEAVDLFHAPDARSPQWTHVARLPLEETGAQELSTTFTLPEGGLQAIRGILGTHPTP
VSCAPGAWTDHDDLVFPVAPSSR

Specific function: Serine proteinase with preferred activity for amino acids with aromatic side groups at the P1' side of the scissible bond [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI31317307, Length=343, Percent_Identity=35.5685131195335, Blast_Score=169, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324576, Length=338, Percent_Identity=36.3905325443787, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320775, Length=411, Percent_Identity=30.6569343065693, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319893, Length=268, Percent_Identity=36.5671641791045, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 69881; Mature: 69881

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKLHLVPLLCLLTTTTSCTEPPAPLAHAVPRQRPIANRYIVVLRPEARAASQGPQKTRE
CCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
HVSNLAKTHGAKVLHTYAHALQGFSAELDDARLEALRADERVAFIEQDAWVRPLVTAETV
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
AWGLDRVDQEDLPLDGLYRPALSGAGVHAYVLDTGIRSTHAEFQGRLGEGFDAVDPDGGA
HHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCC
EDCDGHGTHVAGILGGTTWGVARAVTLHPVRILNCDGEGPLSGIIAGIDWVAAHHQSPAV
CCCCCCCCEEEEECCCCHHHHHEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCE
ANLSIGLEVSEALDQAVRNVVAAGVTAVVAAGNFGVSACDESPARAAEALTVGATNVEDS
EEEEECCCHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCCHHHHHHEEEECCCCCCHH
RASFSNHGPCVDLYAPGEDIRSAGIANDTASEVFSGTSMATPHVAGAAALYLEIHPTATP
HHCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEECCCCH
AQVMDALAGAAISGRVKNAGPGSPDLLLQAGFRRSTGDVHRPWAHVATPFPWSTVRATSR
HHHHHHHHCCHHCCCCCCCCCCCHHHHEECCCCCCCCCCCCCHHHCCCCCCCHHHHHCCE
VRVLAWDDAAVRRVDLWVNGLLRASDDTHPFELDWDTREELNGPATLEVRAYDTALKAWR
EEEEEECCHHHHHHHHHHHHHEECCCCCCCEEECCCCHHHCCCCEEEEEEEHHHHHHHHC
AAPMTVTVRNPDIADFDSTLQAPRCATLAFACDTGVLVRGMGTVGPERHAPNTLGASCAD
CCCEEEEECCCCCCCCHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCHHCC
GIDGTYLITATLEGLRVSSQDGGPLTAGKPVKLTATAFGFLPFLEAVDLFHAPDARSPQW
CCCCCEEEEEEECCEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC
THVARLPLEETGAQELSTTFTLPEGGLQAIRGILGTHPTPVSCAPGAWTDHDDLVFPVAP
CEEEECCHHHCCCHHHHEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
SSR
CCC
>Mature Secondary Structure
MWKLHLVPLLCLLTTTTSCTEPPAPLAHAVPRQRPIANRYIVVLRPEARAASQGPQKTRE
CCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
HVSNLAKTHGAKVLHTYAHALQGFSAELDDARLEALRADERVAFIEQDAWVRPLVTAETV
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
AWGLDRVDQEDLPLDGLYRPALSGAGVHAYVLDTGIRSTHAEFQGRLGEGFDAVDPDGGA
HHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCC
EDCDGHGTHVAGILGGTTWGVARAVTLHPVRILNCDGEGPLSGIIAGIDWVAAHHQSPAV
CCCCCCCCEEEEECCCCHHHHHEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCE
ANLSIGLEVSEALDQAVRNVVAAGVTAVVAAGNFGVSACDESPARAAEALTVGATNVEDS
EEEEECCCHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCCHHHHHHEEEECCCCCCHH
RASFSNHGPCVDLYAPGEDIRSAGIANDTASEVFSGTSMATPHVAGAAALYLEIHPTATP
HHCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEECCCCH
AQVMDALAGAAISGRVKNAGPGSPDLLLQAGFRRSTGDVHRPWAHVATPFPWSTVRATSR
HHHHHHHHCCHHCCCCCCCCCCCHHHHEECCCCCCCCCCCCCHHHCCCCCCCHHHHHCCE
VRVLAWDDAAVRRVDLWVNGLLRASDDTHPFELDWDTREELNGPATLEVRAYDTALKAWR
EEEEEECCHHHHHHHHHHHHHEECCCCCCCEEECCCCHHHCCCCEEEEEEEHHHHHHHHC
AAPMTVTVRNPDIADFDSTLQAPRCATLAFACDTGVLVRGMGTVGPERHAPNTLGASCAD
CCCEEEEECCCCCCCCHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCHHCC
GIDGTYLITATLEGLRVSSQDGGPLTAGKPVKLTATAFGFLPFLEAVDLFHAPDARSPQW
CCCCCEEEEEEECCEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC
THVARLPLEETGAQELSTTFTLPEGGLQAIRGILGTHPTPVSCAPGAWTDHDDLVFPVAP
CEEEECCHHHCCCHHHHEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
SSR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7551039; 1499549 [H]