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The map label for this gene is lytS [H]

Identifier: 108760124

GI number: 108760124

Start: 6354871

End: 6356067

Strand: Direct

Name: lytS [H]

Synonym: MXAN_5082

Alternate gene names: 108760124

Gene position: 6354871-6356067 (Clockwise)

Preceding gene: 108761792

Following gene: 108759263

Centisome position: 69.53

GC content: 71.76

Gene sequence:

>1197_bases
GTGCTTCGGGATGCCGGCTCGCTCGAAACGGGCCGCGCCCATCCACGCCGCCGCCCCAGTGCATACTGCCTGACGACGCC
CATGACGCCCTCTCCGCCCCAGGCCGGCTTCGACTGGAAGTGGCCCCGCATCCGCGCGAAGCCGGCGCTGGCGCTGTTCG
GCTTCTGCCTGCTCATCGGCCTGTGGATGGGGCTCACGCTGTGGCTCACCATCCTCGGGGACGGCGGCACCCTCCCGGGC
TCCCGTCCCTTCCTCTGGGAAATCACCGGGGCGCTCGGCATCTGGGCCGTCTTACCCATCCTCTACACGGCGGTGGTCAA
CGCACCGAGCCCTCGCGTGGGATGGGGGCGCTTCCTGGGCATTCATGCCGTGGCCTTCGTGCTCTTCACCGGCCTGCACA
CCGCGCTGATGGTGGGGACGCGGCAGTTGCTGTACGCGCTGCTCGGCTGGGGCACCTACGACTATGGCGCGCTCGCCTTC
CGCATCCCCATGGAGGCGCAGAAGGACCTCATCTCGTACACGGTCACCGCCACGCTCTGGAGCTTCCTCCAAACCTGGAA
GGAGCGTCAGGCGCGGGCGCTGCGGGAGGCCGCGCTGGAGGCCGAGTTACGAGCGGCCCAACTCCAGTCCCTCACCGGCC
AGCTCCATCCGCACTTCCTCTTCAACGCCCTGAACACCGTCAGCGCGGTGATGTACGAGGACCTCGCGCGCACGGACCGG
CTGCTCAGCGACCTGGGCGGACTGCTGCGCGCCAGCATGGAGCGGCGCGAGGCCACGTGGACGCTGGCCGAGGAGCGAAC
CCAGGCCGCGCGCTTCGTGGCCCTGCTGGCCGCGCGCTTCGGCGAGCGGGTGACGGTGTGCTGGGACGTGGCCCCCGGCC
TGGACGGCGCCCAGGTGCCCTGCTTCGCGCTGCAAGCGCTCGTGGAGAACGCGGTGAAGCACAACCAGGACCGGACAGAG
CCGCTGGAGGTGCGCATCCAGGCCCGGGAGGACGGCAATGGGTGGCGGCTGGAAGTGGAGGACACGGGGCGCGGCTTCGG
CGTGGCCTCGCCCGCGTCCGGCCCCGGCGTGGGCCTGTCGCACCTGGAGCGCATCCTGACGCTGCTCCACGGGGGCCGAG
CGCGGCTGGAGCGGAGCCACGGCCCCGAGGGCGGCGCGCGCGTGTCGCTGTGGCTGCCCCGGGAGACCGCGGCATGA

Upstream 100 bases:

>100_bases
CCGTGGGCCCCTGGGGCCTCTTCCTGGCGGTGCTCACGCTGACGTTCGGTCTCACCTGGGGCCTGTGTGAAGGAGTGGCC
CGGGTGCCCTGGCTGCGAGC

Downstream 100 bases:

>100_bases
CGCGCTTCCAGGTGCTCGTGGCCGATGACGAAGCGCCCGCGCGGGCGAAGGTGAAGCGCCTGCTGGCGGAGGACGCCCGC
TTCGCGCTGGCGGGCGAAGC

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MLRDAGSLETGRAHPRRRPSAYCLTTPMTPSPPQAGFDWKWPRIRAKPALALFGFCLLIGLWMGLTLWLTILGDGGTLPG
SRPFLWEITGALGIWAVLPILYTAVVNAPSPRVGWGRFLGIHAVAFVLFTGLHTALMVGTRQLLYALLGWGTYDYGALAF
RIPMEAQKDLISYTVTATLWSFLQTWKERQARALREAALEAELRAAQLQSLTGQLHPHFLFNALNTVSAVMYEDLARTDR
LLSDLGGLLRASMERREATWTLAEERTQAARFVALLAARFGERVTVCWDVAPGLDGAQVPCFALQALVENAVKHNQDRTE
PLEVRIQAREDGNGWRLEVEDTGRGFGVASPASGPGVGLSHLERILTLLHGGRARLERSHGPEGGARVSLWLPRETAA

Sequences:

>Translated_398_residues
MLRDAGSLETGRAHPRRRPSAYCLTTPMTPSPPQAGFDWKWPRIRAKPALALFGFCLLIGLWMGLTLWLTILGDGGTLPG
SRPFLWEITGALGIWAVLPILYTAVVNAPSPRVGWGRFLGIHAVAFVLFTGLHTALMVGTRQLLYALLGWGTYDYGALAF
RIPMEAQKDLISYTVTATLWSFLQTWKERQARALREAALEAELRAAQLQSLTGQLHPHFLFNALNTVSAVMYEDLARTDR
LLSDLGGLLRASMERREATWTLAEERTQAARFVALLAARFGERVTVCWDVAPGLDGAQVPCFALQALVENAVKHNQDRTE
PLEVRIQAREDGNGWRLEVEDTGRGFGVASPASGPGVGLSHLERILTLLHGGRARLERSHGPEGGARVSLWLPRETAA
>Mature_398_residues
MLRDAGSLETGRAHPRRRPSAYCLTTPMTPSPPQAGFDWKWPRIRAKPALALFGFCLLIGLWMGLTLWLTILGDGGTLPG
SRPFLWEITGALGIWAVLPILYTAVVNAPSPRVGWGRFLGIHAVAFVLFTGLHTALMVGTRQLLYALLGWGTYDYGALAF
RIPMEAQKDLISYTVTATLWSFLQTWKERQARALREAALEAELRAAQLQSLTGQLHPHFLFNALNTVSAVMYEDLARTDR
LLSDLGGLLRASMERREATWTLAEERTQAARFVALLAARFGERVTVCWDVAPGLDGAQVPCFALQALVENAVKHNQDRTE
PLEVRIQAREDGNGWRLEVEDTGRGFGVASPASGPGVGLSHLERILTLLHGGRARLERSHGPEGGARVSLWLPRETAA

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=195, Percent_Identity=32.3076923076923, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788723, Length=218, Percent_Identity=30.7339449541284, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43791; Mature: 43791

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRDAGSLETGRAHPRRRPSAYCLTTPMTPSPPQAGFDWKWPRIRAKPALALFGFCLLIG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LWMGLTLWLTILGDGGTLPGSRPFLWEITGALGIWAVLPILYTAVVNAPSPRVGWGRFLG
HHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IHAVAFVLFTGLHTALMVGTRQLLYALLGWGTYDYGALAFRIPMEAQKDLISYTVTATLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
SFLQTWKERQARALREAALEAELRAAQLQSLTGQLHPHFLFNALNTVSAVMYEDLARTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLSDLGGLLRASMERREATWTLAEERTQAARFVALLAARFGERVTVCWDVAPGLDGAQVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCH
CFALQALVENAVKHNQDRTEPLEVRIQAREDGNGWRLEVEDTGRGFGVASPASGPGVGLS
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHH
HLERILTLLHGGRARLERSHGPEGGARVSLWLPRETAA
HHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MLRDAGSLETGRAHPRRRPSAYCLTTPMTPSPPQAGFDWKWPRIRAKPALALFGFCLLIG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LWMGLTLWLTILGDGGTLPGSRPFLWEITGALGIWAVLPILYTAVVNAPSPRVGWGRFLG
HHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IHAVAFVLFTGLHTALMVGTRQLLYALLGWGTYDYGALAFRIPMEAQKDLISYTVTATLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
SFLQTWKERQARALREAALEAELRAAQLQSLTGQLHPHFLFNALNTVSAVMYEDLARTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLSDLGGLLRASMERREATWTLAEERTQAARFVALLAARFGERVTVCWDVAPGLDGAQVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCH
CFALQALVENAVKHNQDRTEPLEVRIQAREDGNGWRLEVEDTGRGFGVASPASGPGVGLS
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHH
HLERILTLLHGGRARLERSHGPEGGARVSLWLPRETAA
HHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA