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The map label for this gene is argB

Identifier: 108760106

GI number: 108760106

Start: 6378867

End: 6379793

Strand: Direct

Name: argB

Synonym: MXAN_5105

Alternate gene names: 108760106

Gene position: 6378867-6379793 (Clockwise)

Preceding gene: 108758773

Following gene: 108759253

Centisome position: 69.79

GC content: 71.31

Gene sequence:

>927_bases
GTGCCCCTTTCGCCCGACCCCTACTCCGCGCTTCGCCACGCGGCGAAGTACGTGCAGCAGTTCCGCCGCAAGACGTTCGT
GGTGAAGCTCGGCGGCGCCATGCTCAGCGACCCGCGTCTGCGCCGCGCCGCCTGCGAGCAGATTGCCCTTCTGTGGACCT
TCTCCATCCGCCCCGTCGTGGTACACGGCGGCGGTCCGGAGCTGGACACGCTGTGTGACGCCCTCCACCTTCCGGTGGAG
AAGGTGGCCGGCCGCCGCGTCACCTCCGCGCCCGTGCTGGACGCGGCGAAGATGGTGCTCGCGGGCAAGCTGCACACGGA
CCTGCTGGCGGACCTCCAGGCGGCGGGCGTGCCCGCGGTGGGCCTGAGCGGCGTGGACGCCGGCCTCATCAAGGCACGCA
AGCGCCCGCCCGTCATGGTGACGGAAGCCGGTGCCACCGAGGGCAAGCTGGTGGACTACGGCCTGGTGGGTGACATCGAG
CAGGTGGACACCCGCGTGGTGGAGCACCTGCGCTCGGCCGACTACGTGCCCGTCATCGCCCCCCTGTCGGGTGGCACGGA
CGGCGCCGTGTACAACACCAACGCGGACACCGTGGCCGCGGCGCTGGCGGTGGCGCTGTCCGCCGAGAAGCTCTTCTTCC
TGGTCCAGGTTCCGGGCCTGCTGAAGAACGTGAGCGACCCGTCGTCGCTCGTCACGCTGGCCAACCTCACGGACCTGGCC
ACCATGGAGAGCACCGGCGCCATCGCGGGCGGCATGAAGCCCAAGGCGCACGCCATCCGCCACGCGCTCGTGGGCGGCGT
GGGCAGCGTGCACCTGGTCAGCGGCGTGCAGCCCAACGCGCTCCTGGAGGAGGTCTTCACCAACGAGGGCAGCGGCACCA
TGGTCGTGCGGGAGAACGCGCAGAAGCCCGCGGGGGCGGTGGGATGA

Upstream 100 bases:

>100_bases
GCCGGCAATCGCTACCACGTCCAGCGGGCGCTGCTGCACTGGATGCGTTCGCGCTGAGCGGCCCCTCCGCATTCTTCCTT
TCCTGACTTCGAGGTCTCAC

Downstream 100 bases:

>100_bases
CGGCGGCGGAGCTGCTCCAGGCGCTGGTGGCCATCCCCAGCGTGTCAGGTGACGAGGGCCGCATCGCGGACACGGTGTCC
GGGTGGGCGGAAGGCTGGGG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPLSPDPYSALRHAAKYVQQFRRKTFVVKLGGAMLSDPRLRRAACEQIALLWTFSIRPVVVHGGGPELDTLCDALHLPVE
KVAGRRVTSAPVLDAAKMVLAGKLHTDLLADLQAAGVPAVGLSGVDAGLIKARKRPPVMVTEAGATEGKLVDYGLVGDIE
QVDTRVVEHLRSADYVPVIAPLSGGTDGAVYNTNADTVAAALAVALSAEKLFFLVQVPGLLKNVSDPSSLVTLANLTDLA
TMESTGAIAGGMKPKAHAIRHALVGGVGSVHLVSGVQPNALLEEVFTNEGSGTMVVRENAQKPAGAVG

Sequences:

>Translated_308_residues
MPLSPDPYSALRHAAKYVQQFRRKTFVVKLGGAMLSDPRLRRAACEQIALLWTFSIRPVVVHGGGPELDTLCDALHLPVE
KVAGRRVTSAPVLDAAKMVLAGKLHTDLLADLQAAGVPAVGLSGVDAGLIKARKRPPVMVTEAGATEGKLVDYGLVGDIE
QVDTRVVEHLRSADYVPVIAPLSGGTDGAVYNTNADTVAAALAVALSAEKLFFLVQVPGLLKNVSDPSSLVTLANLTDLA
TMESTGAIAGGMKPKAHAIRHALVGGVGSVHLVSGVQPNALLEEVFTNEGSGTMVVRENAQKPAGAVG
>Mature_307_residues
PLSPDPYSALRHAAKYVQQFRRKTFVVKLGGAMLSDPRLRRAACEQIALLWTFSIRPVVVHGGGPELDTLCDALHLPVEK
VAGRRVTSAPVLDAAKMVLAGKLHTDLLADLQAAGVPAVGLSGVDAGLIKARKRPPVMVTEAGATEGKLVDYGLVGDIEQ
VDTRVVEHLRSADYVPVIAPLSGGTDGAVYNTNADTVAAALAVALSAEKLFFLVQVPGLLKNVSDPSSLVTLANLTDLAT
MESTGAIAGGMKPKAHAIRHALVGGVGSVHLVSGVQPNALLEEVFTNEGSGTMVVRENAQKPAGAVG

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=293, Percent_Identity=27.3037542662116, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI145693208, Length=234, Percent_Identity=30.3418803418803, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320913, Length=297, Percent_Identity=24.9158249158249, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_MYXXD (Q1D264)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633259.1
- ProteinModelPortal:   Q1D264
- SMR:   Q1D264
- STRING:   Q1D264
- GeneID:   4103487
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_5105
- TIGR:   MXAN_5105
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- BioCyc:   MXAN246197:MXAN_5105-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32008; Mature: 31877

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: BINDING 86-86 BINDING 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSPDPYSALRHAAKYVQQFRRKTFVVKLGGAMLSDPRLRRAACEQIALLWTFSIRPVV
CCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHCCCHHHHHHHHHEEEEEEECCCEEE
VHGGGPELDTLCDALHLPVEKVAGRRVTSAPVLDAAKMVLAGKLHTDLLADLQAAGVPAV
EECCCCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLSGVDAGLIKARKRPPVMVTEAGATEGKLVDYGLVGDIEQVDTRVVEHLRSADYVPVIA
CCCCCCHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
PLSGGTDGAVYNTNADTVAAALAVALSAEKLFFLVQVPGLLKNVSDPSSLVTLANLTDLA
ECCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEEECCHHHHCCCCHHHHEEHHHHHHHH
TMESTGAIAGGMKPKAHAIRHALVGGVGSVHLVSGVQPNALLEEVFTNEGSGTMVVRENA
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCC
QKPAGAVG
CCCCCCCC
>Mature Secondary Structure 
PLSPDPYSALRHAAKYVQQFRRKTFVVKLGGAMLSDPRLRRAACEQIALLWTFSIRPVV
CCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHCCCHHHHHHHHHEEEEEEECCCEEE
VHGGGPELDTLCDALHLPVEKVAGRRVTSAPVLDAAKMVLAGKLHTDLLADLQAAGVPAV
EECCCCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLSGVDAGLIKARKRPPVMVTEAGATEGKLVDYGLVGDIEQVDTRVVEHLRSADYVPVIA
CCCCCCHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
PLSGGTDGAVYNTNADTVAAALAVALSAEKLFFLVQVPGLLKNVSDPSSLVTLANLTDLA
ECCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEEECCHHHHCCCCHHHHEEHHHHHHHH
TMESTGAIAGGMKPKAHAIRHALVGGVGSVHLVSGVQPNALLEEVFTNEGSGTMVVRENA
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCC
QKPAGAVG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA