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The map label for this gene is algB [H]

Identifier: 108760019

GI number: 108760019

Start: 207019

End: 208380

Strand: Reverse

Name: algB [H]

Synonym: MXAN_0172

Alternate gene names: 108760019

Gene position: 208380-207019 (Counterclockwise)

Preceding gene: 108758771

Following gene: 108760816

Centisome position: 2.28

GC content: 70.93

Gene sequence:

>1362_bases
ATGGACATTGGTGAGCGCCCCATGCGGGTGCTGGTGGTGGACGACGAGCGGAACATCCGCCACACCCTGCGCGTGTGCCT
GGAGGGCTTCGGCTGTGAGGTCCGCGAGGCGGCCACCCCCGAGGCCGCGCTGGCCGCGCTGGCGCAAGGCCCCGCCGACC
TGGCCTTCGTCGACCTGCGGCTCGGCACGGCCAGCGGAATGGAGCTGTTGCCGCGCCTCCTGGCCGAGTCGCCCCACCTG
GACGTCGTGCTCATCACCGCCTACGCCACGTTCGACACGGCGGTGGAGGCGATGCGACGCGGGGCACGGGACTATCTGCC
CAAGCCCTTCACGCCCGCGCAGATTCGCCACGCGGTGGAGAAGGCGCGGCGGCACCAGGAGCTGGCATCGCAGTTGGAGA
ACCTGGAGGGGCAGCTTTCCCAGGCGGTGCCGGAGGCCACGTTGGAGACAGCCTCGCCCGCGATGCACGCGGCCATCGGG
CTGTTGACGCGCGCGGCGGCGTCCGACGCGGCGGTGCTGCTGCGGGGAGAGAGTGGCACCGGCAAGGGGGTGCTCGCCCG
CGCGCTGCATTCGATGAGTGCTCGGCGGCGCCGGCCTTTCGTCACCGTCAACTGTCCCACGCTGTCCGAGCAACTGCTGG
CCAGCGAGCTGTTCGGCCACGTGCGCGGCGCGTTCACCGGCGCGGTGAAGGACCAGCCAGGACGCGTGGAGGCGGCGGAA
GGGGGCACGCTGTTCCTGGATGAAATCGCGGAGATGAGTCCGGGGCTCCAGGCGCAACTGCTGCGCTTCCTCCAGGAGAA
GCAGTTCGAACGGCTGGGCGAGGGACGCACGCGCAAGGCGGACGTGCGGGTGGTGGCGGCGACGAATCGGGACCTGGAGA
AGGACGTGGCCGAGGGGCGCTTCCGGGAGGACCTGCTCTACCGGCTGAACGTCATCGAGGTGAAGCTGCCGTCGCTGCGA
GAGCGGCCGGAGGACCTGCTTTCGCTGGCCCGGCGCTTCGTCTCCTTCTTCGCTCGCGCGGCGCAGCGCCCACCGCCGGA
GCTGTCGCCCGCGACGGAGAAGATGCTGTTGGCCTATGGGTGGCCGGGCAACGTGCGCGAGCTGCGGAATGCAATGGAGC
GAGCGCTCATCGTCTGGCCCGCGGAGGTGCTGGAGCCGCAGGCGTTCCCCGACCGCATCGCCGCGGCGGGGAGTCCGGTG
ATGACCCTGGGCGGGCCGCACACGTTGGAGGACATCGAGCGCGAGCACGTGCTGCGCGTCATGGCCTCGGCGCCCACGTT
GGATGAGGCAGCGCGGGTGCTGGGCATCGACGCGTCCACGCTGTGGCGGAAGCGGAAGAAGTACGAGTCGGGCGAGGGCT
GA

Upstream 100 bases:

>100_bases
GAGGCAACCGCCAACAAGCCGGGCGGCCATTGCGTGAGCTCCCGCACGCCGCGCGGGAGTCTGACCGCGCGCTGGCGCGG
ATTGCTCCTAGGATGAAGTC

Downstream 100 bases:

>100_bases
GCACGGGCCTGGGAGCGCCCGTGGTGTTCCACGGGAGCAGAGCGGGCAGGGCTTCTCCTCGTGCCTGGAGCGGTGATTGC
GACGTCCTGCGAGCATGCGG

Product: sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDIGERPMRVLVVDDERNIRHTLRVCLEGFGCEVREAATPEAALAALAQGPADLAFVDLRLGTASGMELLPRLLAESPHL
DVVLITAYATFDTAVEAMRRGARDYLPKPFTPAQIRHAVEKARRHQELASQLENLEGQLSQAVPEATLETASPAMHAAIG
LLTRAAASDAAVLLRGESGTGKGVLARALHSMSARRRRPFVTVNCPTLSEQLLASELFGHVRGAFTGAVKDQPGRVEAAE
GGTLFLDEIAEMSPGLQAQLLRFLQEKQFERLGEGRTRKADVRVVAATNRDLEKDVAEGRFREDLLYRLNVIEVKLPSLR
ERPEDLLSLARRFVSFFARAAQRPPPELSPATEKMLLAYGWPGNVRELRNAMERALIVWPAEVLEPQAFPDRIAAAGSPV
MTLGGPHTLEDIEREHVLRVMASAPTLDEAARVLGIDASTLWRKRKKYESGEG

Sequences:

>Translated_453_residues
MDIGERPMRVLVVDDERNIRHTLRVCLEGFGCEVREAATPEAALAALAQGPADLAFVDLRLGTASGMELLPRLLAESPHL
DVVLITAYATFDTAVEAMRRGARDYLPKPFTPAQIRHAVEKARRHQELASQLENLEGQLSQAVPEATLETASPAMHAAIG
LLTRAAASDAAVLLRGESGTGKGVLARALHSMSARRRRPFVTVNCPTLSEQLLASELFGHVRGAFTGAVKDQPGRVEAAE
GGTLFLDEIAEMSPGLQAQLLRFLQEKQFERLGEGRTRKADVRVVAATNRDLEKDVAEGRFREDLLYRLNVIEVKLPSLR
ERPEDLLSLARRFVSFFARAAQRPPPELSPATEKMLLAYGWPGNVRELRNAMERALIVWPAEVLEPQAFPDRIAAAGSPV
MTLGGPHTLEDIEREHVLRVMASAPTLDEAARVLGIDASTLWRKRKKYESGEG
>Mature_453_residues
MDIGERPMRVLVVDDERNIRHTLRVCLEGFGCEVREAATPEAALAALAQGPADLAFVDLRLGTASGMELLPRLLAESPHL
DVVLITAYATFDTAVEAMRRGARDYLPKPFTPAQIRHAVEKARRHQELASQLENLEGQLSQAVPEATLETASPAMHAAIG
LLTRAAASDAAVLLRGESGTGKGVLARALHSMSARRRRPFVTVNCPTLSEQLLASELFGHVRGAFTGAVKDQPGRVEAAE
GGTLFLDEIAEMSPGLQAQLLRFLQEKQFERLGEGRTRKADVRVVAATNRDLEKDVAEGRFREDLLYRLNVIEVKLPSLR
ERPEDLLSLARRFVSFFARAAQRPPPELSPATEKMLLAYGWPGNVRELRNAMERALIVWPAEVLEPQAFPDRIAAAGSPV
MTLGGPHTLEDIEREHVLRVMASAPTLDEAARVLGIDASTLWRKRKKYESGEG

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=449, Percent_Identity=40.3118040089087, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1790437, Length=443, Percent_Identity=39.7291196388262, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI1790299, Length=467, Percent_Identity=39.4004282655246, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1788905, Length=385, Percent_Identity=39.4805194805195, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1789233, Length=373, Percent_Identity=37.2654155495979, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI87082117, Length=227, Percent_Identity=50.2202643171806, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789087, Length=329, Percent_Identity=41.0334346504559, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=40.625, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1787583, Length=336, Percent_Identity=36.6071428571429, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1786524, Length=318, Percent_Identity=40.251572327044, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87081872, Length=216, Percent_Identity=46.7592592592593, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1789828, Length=207, Percent_Identity=40.5797101449275, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87081858, Length=351, Percent_Identity=29.9145299145299, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1787375, Length=129, Percent_Identity=34.1085271317829, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49728; Mature: 49728

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIGERPMRVLVVDDERNIRHTLRVCLEGFGCEVREAATPEAALAALAQGPADLAFVDLR
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCEEEEEEE
LGTASGMELLPRLLAESPHLDVVLITAYATFDTAVEAMRRGARDYLPKPFTPAQIRHAVE
ECCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHH
KARRHQELASQLENLEGQLSQAVPEATLETASPAMHAAIGLLTRAAASDAAVLLRGESGT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
GKGVLARALHSMSARRRRPFVTVNCPTLSEQLLASELFGHVRGAFTGAVKDQPGRVEAAE
CHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GGTLFLDEIAEMSPGLQAQLLRFLQEKQFERLGEGRTRKADVRVVAATNRDLEKDVAEGR
CCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHCCH
FREDLLYRLNVIEVKLPSLRERPEDLLSLARRFVSFFARAAQRPPPELSPATEKMLLAYG
HHHHHHHHHHHEEEECCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEC
WPGNVRELRNAMERALIVWPAEVLEPQAFPDRIAAAGSPVMTLGGPHTLEDIEREHVLRV
CCCCHHHHHHHHHHHEEECCHHHHCCCCCHHHHHHCCCCEEECCCCCCHHHHHHHHHHHH
MASAPTLDEAARVLGIDASTLWRKRKKYESGEG
HHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDIGERPMRVLVVDDERNIRHTLRVCLEGFGCEVREAATPEAALAALAQGPADLAFVDLR
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCEEEEEEE
LGTASGMELLPRLLAESPHLDVVLITAYATFDTAVEAMRRGARDYLPKPFTPAQIRHAVE
ECCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHH
KARRHQELASQLENLEGQLSQAVPEATLETASPAMHAAIGLLTRAAASDAAVLLRGESGT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
GKGVLARALHSMSARRRRPFVTVNCPTLSEQLLASELFGHVRGAFTGAVKDQPGRVEAAE
CHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GGTLFLDEIAEMSPGLQAQLLRFLQEKQFERLGEGRTRKADVRVVAATNRDLEKDVAEGR
CCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHCCH
FREDLLYRLNVIEVKLPSLRERPEDLLSLARRFVSFFARAAQRPPPELSPATEKMLLAYG
HHHHHHHHHHHEEEECCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEC
WPGNVRELRNAMERALIVWPAEVLEPQAFPDRIAAAGSPVMTLGGPHTLEDIEREHVLRV
CCCCHHHHHHHHHHHEEECCHHHHCCCCCHHHHHHCCCCEEECCCCCCHHHHHHHHHHHH
MASAPTLDEAARVLGIDASTLWRKRKKYESGEG
HHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1899859; 1738315; 10984043; 9473053 [H]